iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117546

UUCD1 version

UUC-TaR-00334

Ensembl Protein ID

ENSTRUP00000017014.1

UniProt Accession

H2SX76; H2SX76_TAKRU

Protein Name

Uncharacterized protein

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006927.1	ENSTRUT00000017087.1	ENSTRUP00000017014.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.60e-17	64.1	29	92
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-12	46.3	128	158

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D++l v+ + f+ah+ivLaa+S++F a+f++el e+  k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 29   CDITLRVESTDFPAHRIVLAACSDYFCAMFTSELAEKG-KPFVDIQGLTAGTMEILLDFVYTETV 92
           8***********************************98.***********************875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++fA++++c +L++aa+ f +khF
   Q: 128  PSNCLGIRDFAETHNCLELMQAAELFSQKHF 158
           89***************************** PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MAPKDIMTNS HAKSILNAMN SLRKSNTLCD ITLRVESTDF PAHRIVLAAC SDYFCAMFTS 60
ELAEKGKPFV DIQGLTAGTM EILLDFVYTE TVLVTVENVQ ELLPAACLLQ LKGVKRACCD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCTA AAGATATAAT GACTAATTCC CACGCCAAAT CCATCCTTAA CGCCATGAAT 60
TCACTCCGCA AAAGCAACAC ACTCTGCGAC ATCACTCTGA GGGTGGAGAG CACAGATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	90.18	0.00e+00	1047.00
IUUC-Apl-003339	Anas platyrhynchos	89.60	0.00e+00	969.00
IUUC-Aca-004418	Anolis carolinensis	89.36	0.00e+00	1053.00
IUUC-Ath-007066	Arabidopsis thaliana	31.47	1.00e-38	154.00
IUUC-Ame-011906	Astyanax mexicanus	80.63	0.00e+00	919.00
IUUC-Bta-012979	Bos taurus	88.48	0.00e+00	1043.00
IUUC-Cja-019582	Callithrix jacchus	90.25	0.00e+00	1063.00
IUUC-Cfa-020716	Canis familiaris	90.60	0.00e+00	1066.00
IUUC-Cpo-022013	Cavia porcellus	90.43	0.00e+00	1065.00
IUUC-Cre-022752	Chlamydomonas reinhardtii	27.73	1.00e-14	76.30
IUUC-Csa-023424	Chlorocebus sabaeus	90.44	0.00e+00	986.00
IUUC-Cho-024586	Choloepus hoffmanni	74.47	0.00e+00	835.00
IUUC-Dre-028344	Danio rerio	94.82	3.00e-177	613.00
IUUC-Dno-028854	Dasypus novemcinctus	90.60	0.00e+00	1066.00
IUUC-Dor-030403	Dipodomys ordii	90.43	0.00e+00	1063.00
IUUC-Ete-032963	Echinops telfairi	88.67	0.00e+00	920.00
IUUC-Eca-033282	Equus caballus	90.78	0.00e+00	1068.00
IUUC-Eeu-034933	Erinaceus europaeus	90.59	9.00e-135	473.00
IUUC-Fca-035487	Felis catus	90.60	0.00e+00	1066.00
IUUC-Fal-037059	Ficedula albicollis	89.68	0.00e+00	1048.00
IUUC-Gmo-039564	Gadus morhua	96.10	0.00e+00	1138.00
IUUC-Gga-040629	Gallus gallus	89.50	0.00e+00	1053.00
IUUC-Gac-042526	Gasterosteus aculeatus	97.34	0.00e+00	1145.00
IUUC-Ggo-044839	Gorilla gorilla	90.43	0.00e+00	1065.00
IUUC-Hsa-046742	Homo sapiens	90.43	0.00e+00	1065.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	90.43	0.00e+00	1064.00
IUUC-Lch-049540	Latimeria chalumnae	88.83	0.00e+00	1063.00
IUUC-Loc-051923	Lepisosteus oculatus	91.31	0.00e+00	1067.00
IUUC-Laf-054370	Loxodonta africana	90.25	0.00e+00	1065.00
IUUC-Mcc-054852	Macaca mulatta	90.43	0.00e+00	1065.00
IUUC-Mga-059486	Meleagris gallopavo	87.87	0.00e+00	954.00
IUUC-Mmr-061777	Microcebus murinus	90.60	0.00e+00	1064.00
IUUC-Mdo-061990	Monodelphis domestica	90.07	0.00e+00	1059.00
IUUC-Mmu-064053	Mus musculus	90.43	0.00e+00	1065.00
IUUC-Mpu-066623	Mustela putorius furo	77.99	0.00e+00	750.00
IUUC-Mlu-067648	Myotis lucifugus	90.07	0.00e+00	1081.00
IUUC-Nle-069714	Nomascus leucogenys	90.25	0.00e+00	1063.00
IUUC-Opr-071143	Ochotona princeps	84.22	0.00e+00	969.00
IUUC-Ont-071848	Oreochromis niloticus	98.05	0.00e+00	1156.00
IUUC-Oan-073041	Ornithorhynchus anatinus	87.77	3.00e-148	517.00
IUUC-Ocu-074379	Oryctolagus cuniculus	90.07	0.00e+00	1062.00
IUUC-Ogl-077595	Oryza glaberrima	31.62	3.00e-34	140.00
IUUC-Oin-079973	Oryza indica	32.05	9.00e-34	138.00
IUUC-Osa-085891	Oryza sativa	32.05	2.00e-35	144.00
IUUC-Ola-087469	Oryzias latipes	98.05	0.00e+00	1156.00
IUUC-Oar-090144	Ovis aries	89.72	0.00e+00	1056.00
IUUC-Ptr-091406	Pan troglodytes	90.43	0.00e+00	1065.00
IUUC-Pan-092762	Papio anubis	89.38	0.00e+00	1045.00
IUUC-Psi-093391	Pelodiscus sinensis	89.36	0.00e+00	1056.00
IUUC-Pma-094134	Petromyzon marinus	72.60	0.00e+00	806.00
IUUC-Pfo-096404	Poecilia formosa	98.40	0.00e+00	1157.00
IUUC-Pab-098425	Pongo abelii	89.72	0.00e+00	1055.00
IUUC-Pca-101093	Procavia capensis	89.66	6.00e-158	550.00
IUUC-Pva-102239	Pteropus vampyrus	80.85	0.00e+00	944.00
IUUC-Rno-104921	Rattus norvegicus	90.43	0.00e+00	1066.00
IUUC-Sha-106625	Sarcophilus harrisii	90.78	0.00e+00	1067.00
IUUC-Sar-113468	Sorex araneus	79.90	0.00e+00	657.00
IUUC-Ssc-116106	Sus scrofa	90.43	0.00e+00	1063.00
IUUC-Tgu-117402	Taeniopygia guttata	61.50	0.00e+00	632.00
IUUC-Tsy-118802	Tarsius syrichta	81.56	0.00e+00	925.00
IUUC-Tni-119999	Tetraodon nigroviridis	99.11	0.00e+00	1152.00
IUUC-Tbe-127987	Tupaia belangeri	90.65	0.00e+00	890.00
IUUC-Ttr-128613	Tursiops truncatus	84.19	0.00e+00	969.00
IUUC-Xtr-132401	Xenopus tropicalis	87.70	2.00e-166	577.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence