iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065800

Ensembl Protein ID

ENSMPUP00000002242.1

UniProt Accession

M3XT42; M3XT42_MUSPF

Genbank Protein ID

ENSMPUP00000002242

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01040863

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000002266.1	ENSMPUT00000002288.1	ENSMPUP00000002242.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-17	62.8	69	134
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-09	36.7	168	199

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 69   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVKFVYSSRLTL 134
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 168  PSNCLAVRAFAESHNRIDLMDMADQYACEHFT 199
           89*****************************7 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MLQMASESVN AKQARNHCTK VKRQQHQQIK NRSSISDGDG EDSFIFEANE AWKDFHGSLL 60
RFYENGELCD VTLKVGSKLI SCHKLVLACV IPYFRAMFLS EMAEAKQTLI EIRDFDGDAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCAGAGCA CGCGGGCAAA GTGACAGGAA TAGAAACGGA AGTCTTCTCC CTCCCCCCCA 60
TTTTAAAAAA GATATAATCC CAAGGAACAC TCAGCGCGCG GGAGGGGGAG TTGATGGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	99.52	0.00e+00	1262.00
IUUC-Atr-002726	Amborella trichopoda	35.48	3.00e-43	170.00
IUUC-Apl-003978	Anas platyrhynchos	88.87	0.00e+00	1157.00
IUUC-Aca-004958	Anolis carolinensis	84.68	0.00e+00	1078.00
IUUC-Ame-011139	Astyanax mexicanus	81.42	0.00e+00	1066.00
IUUC-Bta-013142	Bos taurus	96.45	0.00e+00	1224.00
IUUC-Bdi-014143	Brachypodium distachyon	39.17	3.00e-43	169.00
IUUC-Cel-018551	Caenorhabditis elegans	42.45	4.00e-130	458.00
IUUC-Cja-019650	Callithrix jacchus	96.94	0.00e+00	1258.00
IUUC-Cfa-021046	Canis familiaris	98.71	0.00e+00	1249.00
IUUC-Cpo-022445	Cavia porcellus	93.70	0.00e+00	1166.00
IUUC-Csa-023642	Chlorocebus sabaeus	97.58	0.00e+00	1264.00
IUUC-Cho-025012	Choloepus hoffmanni	79.55	0.00e+00	890.00
IUUC-Dre-027723	Danio rerio	81.94	0.00e+00	1057.00
IUUC-Dno-028964	Dasypus novemcinctus	96.88	0.00e+00	1031.00
IUUC-Dor-030899	Dipodomys ordii	82.78	4.00e-136	478.00
IUUC-Ete-032815	Echinops telfairi	92.73	0.00e+00	1209.00
IUUC-Eca-034162	Equus caballus	97.25	0.00e+00	1214.00
IUUC-Eeu-034660	Erinaceus europaeus	94.67	0.00e+00	1201.00
IUUC-Fca-035659	Felis catus	98.87	0.00e+00	1256.00
IUUC-Fal-037619	Ficedula albicollis	90.47	0.00e+00	1172.00
IUUC-Fox-037999	Fusarium oxysporum	31.17	3.00e-08	52.00
IUUC-Gmo-038546	Gadus morhua	84.25	0.00e+00	1050.00
IUUC-Ggr-040041	Gaeumannomyces graminis	30.82	5.00e-07	48.50
IUUC-Gga-040770	Gallus gallus	90.00	0.00e+00	1135.00
IUUC-Gac-042557	Gasterosteus aculeatus	77.92	0.00e+00	1038.00
IUUC-Gma-043533	Glycine max	31.23	6.00e-38	152.00
IUUC-Ggo-044741	Gorilla gorilla	97.26	0.00e+00	1263.00
IUUC-Hsa-046025	Homo sapiens	97.10	0.00e+00	1261.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	97.81	0.00e+00	1105.00
IUUC-Loc-052834	Lepisosteus oculatus	82.88	0.00e+00	1008.00
IUUC-Laf-054513	Loxodonta africana	96.45	0.00e+00	1227.00
IUUC-Mcc-054707	Macaca mulatta	97.42	0.00e+00	1260.00
IUUC-Meu-056779	Macropus eugenii	90.19	0.00e+00	1163.00
IUUC-Mga-059676	Meleagris gallopavo	89.84	0.00e+00	1135.00
IUUC-Mmr-061359	Microcebus murinus	95.65	0.00e+00	1207.00
IUUC-Mdo-062527	Monodelphis domestica	89.14	0.00e+00	1159.00
IUUC-Mmu-063112	Mus musculus	92.21	0.00e+00	1208.00
IUUC-Mac-064682	Musa acuminata	36.36	2.00e-42	167.00
IUUC-Mlu-067536	Myotis lucifugus	95.77	0.00e+00	1175.00
IUUC-Nle-069397	Nomascus leucogenys	97.26	0.00e+00	1261.00
IUUC-Opr-070599	Ochotona princeps	95.69	0.00e+00	1026.00
IUUC-Ont-072580	Oreochromis niloticus	81.38	0.00e+00	1056.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.76	0.00e+00	1179.00
IUUC-Ocu-074026	Oryctolagus cuniculus	96.61	0.00e+00	1211.00
IUUC-Obr-076181	Oryza brachyantha	32.03	4.00e-36	146.00
IUUC-Ola-086776	Oryzias latipes	80.07	0.00e+00	1010.00
IUUC-Oga-088651	Otolemur garnettii	96.46	0.00e+00	1219.00
IUUC-Oar-089567	Ovis aries	95.32	0.00e+00	1199.00
IUUC-Ptr-091564	Pan troglodytes	97.26	0.00e+00	1263.00
IUUC-Pan-092578	Papio anubis	97.58	0.00e+00	1264.00
IUUC-Psi-093635	Pelodiscus sinensis	89.09	0.00e+00	1105.00
IUUC-Pma-094660	Petromyzon marinus	61.82	0.00e+00	761.00
IUUC-Pfo-097507	Poecilia formosa	79.83	0.00e+00	982.00
IUUC-Pab-098025	Pongo abelii	97.26	0.00e+00	1263.00
IUUC-Pca-101046	Procavia capensis	86.58	0.00e+00	630.00
IUUC-Ppe-101154	Prunus persica	33.33	4.00e-39	156.00
IUUC-Pva-102359	Pteropus vampyrus	97.27	0.00e+00	903.00
IUUC-Rno-105750	Rattus norvegicus	92.91	0.00e+00	1186.00
IUUC-Sha-107513	Sarcophilus harrisii	92.26	0.00e+00	1198.00
IUUC-Sly-111482	Solanum lycopersicum	31.91	1.00e-41	164.00
IUUC-Stu-112032	Solanum tuberosum	33.07	3.00e-43	169.00
IUUC-Sar-113616	Sorex araneus	71.33	9.00e-119	420.00
IUUC-Ssc-116205	Sus scrofa	97.27	0.00e+00	1041.00
IUUC-Tgu-117435	Taeniopygia guttata	90.63	0.00e+00	1165.00
IUUC-Tru-118709	Takifugu rubripes	81.09	0.00e+00	1054.00
IUUC-Tsy-119466	Tarsius syrichta	98.18	0.00e+00	1104.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.79	0.00e+00	1047.00
IUUC-Tca-121074	Theobroma cacao	28.91	6.00e-36	145.00
IUUC-Tae-124761	Triticum aestivum	34.80	5.00e-39	156.00
IUUC-Tbe-127704	Tupaia belangeri	96.53	0.00e+00	1065.00
IUUC-Ttr-128892	Tursiops truncatus	97.41	0.00e+00	923.00
IUUC-Vpa-130545	Vicugna pacos	97.65	0.00e+00	1047.00
IUUC-Xtr-132289	Xenopus tropicalis	83.99	0.00e+00	1035.00
IUUC-Xma-133419	Xiphophorus maculatus	83.46	0.00e+00	949.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence