iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	88.41	6.00e-119	423.00	IUUC-Cpo-021870
E3 adaptor/Cullin RING/SCF/F-box	92.24	7.00e-125	444.00	IUUC-Hsa-045945
E3 adaptor/Cullin RING/SCF/F-box	96.51	3.00e-128	455.00	IUUC-Mmu-064264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDGDGDPESV SHPEEASPEE QPEEAGAEAS AEEEQPREEE EEETEAVEYL AELPEPLLLR 60
VLAELPATEL VQACRLVCLR WKELVDGAPL WLLKCQQEGL VPEGSADDER DHWQQFYFLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGCTCCA GGACTCGCCA CCCGCAGCGC TCAGGCTCCA CTCTCGTCAG CGCCGCAGCG 60
ATGGATGGAG ATGGTGATCC AGGTATCCGC TGCTGGCCCC GCTAGATACA GACCCGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007397--F-box-assoc_dom
IPR001810--F-box_dom
IPR008979--Galactose-bd-like

PROSITE

PS51114--FBA
PS50181--FBOX

Pfam

PF00646--F-box
PF04300--FBA

SMART

SM01198--FBA

Gene Ontology

GO:0005829--C:cytosol
GO:0043197--C:dendritic spine
GO:0070062--C:extracellular exosome
GO:0019005--C:SCF ubiquitin ligase complex
GO:0001540--F:beta-amyloid binding
GO:0030246--F:carbohydrate binding
GO:0006516--P:glycoprotein catabolic process
GO:0008285--P:negative regulation of cell proliferation
GO:0016567--P:protein ubiquitination
GO:0031396--P:regulation of protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001683	Ailuropoda melanoleuca	82.94	6.00e-123	433.00
IUUC-Apl-003298	Anas platyrhynchos	67.36	1.00e-96	345.00
IUUC-Aca-005151	Anolis carolinensis	64.44	2.00e-87	315.00
IUUC-Ame-011216	Astyanax mexicanus	50.46	7.00e-56	209.00
IUUC-Bta-013523	Bos taurus	82.94	5.00e-127	446.00
IUUC-Cja-019449	Callithrix jacchus	92.92	2.00e-123	434.00
IUUC-Cfa-021011	Canis familiaris	90.83	2.00e-127	447.00
IUUC-Cpo-021870	Cavia porcellus	82.33	1.00e-122	432.00
IUUC-Csa-024225	Chlorocebus sabaeus	92.48	2.00e-123	434.00
IUUC-Dno-029067	Dasypus novemcinctus	89.67	9.00e-95	339.00
IUUC-Dor-030945	Dipodomys ordii	91.34	1.00e-123	435.00
IUUC-Ete-032537	Echinops telfairi	89.82	3.00e-113	401.00
IUUC-Eca-033888	Equus caballus	92.04	4.00e-122	430.00
IUUC-Eeu-034498	Erinaceus europaeus	89.26	1.00e-75	275.00
IUUC-Fca-035793	Felis catus	85.91	1.00e-119	422.00
IUUC-Fal-037415	Ficedula albicollis	67.78	1.00e-91	328.00
IUUC-Gmo-039430	Gadus morhua	56.07	6.00e-47	179.00
IUUC-Gga-040818	Gallus gallus	68.20	4.00e-98	350.00
IUUC-Ggo-045653	Gorilla gorilla	92.92	4.00e-117	414.00
IUUC-Hsa-045945	Homo sapiens	92.48	7.00e-117	413.00
IUUC-Itr-048593	Ictidomys tridecemlineatus	94.74	1.00e-125	442.00
IUUC-Lch-049839	Latimeria chalumnae	52.72	2.00e-77	281.00
IUUC-Laf-053956	Loxodonta africana	78.22	5.00e-123	433.00
IUUC-Mcc-054799	Macaca mulatta	92.92	1.00e-123	436.00
IUUC-Mtr-057935	Medicago truncatula	27.94	2.40e-01	29.60
IUUC-Mga-059915	Meleagris gallopavo	68.20	2.00e-98	351.00
IUUC-Mdo-062296	Monodelphis domestica	71.13	3.00e-101	360.00
IUUC-Mmu-064264	Mus musculus	96.51	2.00e-129	454.00
IUUC-Mpu-066032	Mustela putorius furo	90.04	6.00e-123	433.00
IUUC-Mlu-066950	Myotis lucifugus	73.00	1.00e-111	395.00
IUUC-Nle-069626	Nomascus leucogenys	92.14	1.00e-122	432.00
IUUC-Opr-070783	Ochotona princeps	91.81	6.00e-125	439.00
IUUC-Oan-073742	Ornithorhynchus anatinus	73.11	7.00e-92	329.00
IUUC-Oga-088822	Otolemur garnettii	90.79	4.00e-120	424.00
IUUC-Oar-089801	Ovis aries	90.48	3.00e-123	434.00
IUUC-Ptr-091637	Pan troglodytes	92.48	7.00e-117	413.00
IUUC-Pan-092330	Papio anubis	92.92	9.00e-124	436.00
IUUC-Psi-093974	Pelodiscus sinensis	66.53	2.00e-95	341.00
IUUC-Ppa-095869	Physcomitrella patens	21.86	1.00e-12	67.40
IUUC-Pab-097688	Pongo abelii	93.36	7.00e-124	436.00
IUUC-Pca-100828	Procavia capensis	93.29	2.00e-79	288.00
IUUC-Pva-102795	Pteropus vampyrus	91.70	2.00e-123	434.00
IUUC-Smo-108894	Selaginella moellendorffii	20.92	3.00e-08	52.40
IUUC-Stu-112556	Solanum tuberosum	34.04	3.70e-02	31.60
IUUC-Ssc-115796	Sus scrofa	90.43	2.00e-122	431.00
IUUC-Tgu-116848	Taeniopygia guttata	67.36	2.00e-89	321.00
IUUC-Tre-121870	Trichoderma reesei	50.00	4.40e-01	29.30
IUUC-Tvi-122582	Trichoderma virens	25.00	6.10e-01	28.10
IUUC-Tbe-127621	Tupaia belangeri	90.30	2.00e-84	305.00
IUUC-Ttr-128809	Tursiops truncatus	87.28	8.00e-109	386.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence