iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012715

Ensembl Protein ID

ENSBTAP00000021259.3

UniProt Accession

Q2KIC2; ETV1_BOVIN

Genbank Protein ID

AAI12693.1

Protein Name

ETS translocation variant 1

Genbank Nucleotide ID

BC112692

Gene Name

ETV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000015981.3	ENSBTAT00000021259.3	ENSBTAP00000021259.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/DCX/DDB1	26.37	7.80e-02	33.50	IUUC-Sce-106248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Functional Description
(View)

Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.

Protein Sequence
(Fasta)

MDGFYDQQVP YMVTNNQRGR NCNEKPTNVR KRKFINRDLA HDSEELFQDL SQLQETWLAE 60
AQVPDNDEQF VPDYQAESLA FHGLPLKIKK EPHSPCSELG SACSQEQPFK FSYGEKCLYN 120

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Nucleotide Sequence
(Fasta)

AGAGGCGCTT TCGGCTTCCA AGGGGGAAGT GCTGGGCAAT AATTAATGTT TTTATTAAAA 60
TTGGAGGGAA TTTTTTGCAG CCGTTCGCCT AGCGTGGCTT TCAGGTGGGT CTTTCCGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation

Interpro

IPR000418--Ets_dom
IPR006715--ETS_PEA3_N
IPR032928--ETS_V1
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS00345--ETS_DOMAIN_1
PS00346--ETS_DOMAIN_2
PS50061--ETS_DOMAIN_3

Pfam

PF00178--Ets
PF04621--ETS_PEA3_N

PRINTS

PR00454--ETSDOMAIN

SMART

SM00413--ETS

Gene Ontology

GO:0005634--C:nucleus
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0007411--P:axon guidance
GO:0030154--P:cell differentiation
GO:0007638--P:mechanosensory behavior
GO:0007517--P:muscle organ development
GO:0048935--P:peripheral nervous system neuron development
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

bta:540846

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001295	Ailuropoda melanoleuca	99.16	0.00e+00	956.00
IUUC-Apl-003730	Anas platyrhynchos	95.39	0.00e+00	925.00
IUUC-Cfa-020291	Canis familiaris	99.16	0.00e+00	956.00
IUUC-Cpo-021597	Cavia porcellus	97.90	0.00e+00	944.00
IUUC-Csa-023507	Chlorocebus sabaeus	98.32	0.00e+00	947.00
IUUC-Dno-029500	Dasypus novemcinctus	97.69	0.00e+00	939.00
IUUC-Eca-033486	Equus caballus	98.74	0.00e+00	947.00
IUUC-Eeu-034839	Erinaceus europaeus	92.47	0.00e+00	881.00
IUUC-Fal-037436	Ficedula albicollis	95.39	0.00e+00	925.00
IUUC-Gga-040301	Gallus gallus	95.18	0.00e+00	923.00
IUUC-Mga-059333	Meleagris gallopavo	95.18	0.00e+00	923.00
IUUC-Mlu-067954	Myotis lucifugus	97.90	0.00e+00	943.00
IUUC-Oga-088263	Otolemur garnettii	92.72	0.00e+00	882.00
IUUC-Oar-090302	Ovis aries	98.96	0.00e+00	956.00
IUUC-Ptr-090472	Pan troglodytes	98.32	0.00e+00	947.00
IUUC-Pan-091878	Papio anubis	97.51	0.00e+00	941.00
IUUC-Pab-097577	Pongo abelii	98.32	0.00e+00	947.00
IUUC-Pva-102919	Pteropus vampyrus	95.74	0.00e+00	902.00
IUUC-Rno-105702	Rattus norvegicus	97.48	0.00e+00	941.00
IUUC-Sce-106248	Saccharomyces cerevisiae	26.37	8.40e-02	33.50
IUUC-Ssc-115379	Sus scrofa	98.95	0.00e+00	952.00
IUUC-Tgu-116895	Taeniopygia guttata	94.56	0.00e+00	913.00
IUUC-Ttr-128445	Tursiops truncatus	85.28	0.00e+00	800.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence