iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011330

Ensembl Protein ID

ENSAMXP00000005462.1

UniProt Accession

W5KD01; W5KD01_ASTMX

Genbank Protein ID

ENSAMXP00000005462

Protein Name

Anaphase-promoting complex subunit 10

Genbank Nucleotide ID

APWO01029428

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000005332.1	ENSAMXT00000005462.1	ENSAMXP00000005462.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	91.16	3.00e-79	291.00	IUUC-Hsa-046971
E3 adaptor/Cullin RING/APC_C/APC_C	35.07	4.00e-20	92.00	IUUC-Sce-106448

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Astyanax mexicanus

Functional Description
(View)

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

Protein Sequence
(Fasta)

MLCFSLLLDS LVISVPLSLC LFLCVLIGFG VDQLRDDNLE TYWQSDGSQP HLVNIQFRRK 60
TTVKMLCIYA DYKSDESYTP SKISVRVGNN FHNLLEIRQL EMVEPSGWIH IPLLDLVNNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCTAGCTA AATGTGTGAC TATAATATCA ATCCCCAAAT AAACTAAATG ATAGCACAGT 60
TGAGGTAAAT NTCCATTATT CCATTAATCC ATTATTCCTG GTATAATTCT TCAGTATTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0472--Membrane
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR016901--APC10
IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like

PROSITE

PS51284--DOC

Pfam

PF03256--ANAPC10

SMART

SM01337--APC10

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0016021--C:integral component of membrane
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000560	Aegilops tauschii	55.95	4.00e-21	93.60
IUUC-Aml-001522	Ailuropoda melanoleuca	91.16	2.00e-80	291.00
IUUC-Atr-002797	Amborella trichopoda	57.72	2.00e-45	175.00
IUUC-Apl-004185	Anas platyrhynchos	92.52	2.00e-81	294.00
IUUC-Aca-004900	Anolis carolinensis	91.84	1.00e-80	291.00
IUUC-Aly-005760	Arabidopsis lyrata	54.36	2.00e-40	158.00
IUUC-Ath-007516	Arabidopsis thaliana	54.36	2.00e-40	158.00
IUUC-Ago-007889	Ashbya gossypii	30.32	7.00e-20	90.50
IUUC-Acl-008130	Aspergillus clavatus	40.70	7.00e-15	75.10
IUUC-Afl-008640	Aspergillus flavus	39.53	6.00e-14	72.00
IUUC-Afu-009101	Aspergillus fumigatus	40.70	3.00e-14	73.20
IUUC-Ani-009484	Aspergillus nidulans	39.53	3.00e-14	73.20
IUUC-Ang-009847	Aspergillus niger	37.21	3.00e-13	69.70
IUUC-Aor-010077	Aspergillus oryzae	39.53	6.00e-14	72.00
IUUC-Ate-010544	Aspergillus terreus	37.08	4.00e-14	72.40
IUUC-Bgr-011978	Blumeria graminis	41.04	7.00e-30	123.00
IUUC-Bta-013351	Bos taurus	91.16	2.00e-80	291.00
IUUC-Bci-013611	Botrytis cinerea	44.09	4.00e-29	121.00
IUUC-Bdi-014443	Brachypodium distachyon	55.03	8.00e-42	163.00
IUUC-Bol-015534	Brassica oleracea	56.67	3.00e-46	177.00
IUUC-Bra-017298	Brassica rapa	56.67	3.00e-46	177.00
IUUC-Cel-018170	Caenorhabditis elegans	47.97	1.00e-33	135.00
IUUC-Cja-019877	Callithrix jacchus	91.16	2.00e-80	291.00
IUUC-Cfa-020698	Canis familiaris	91.16	2.00e-80	291.00
IUUC-Cpo-022007	Cavia porcellus	90.48	8.00e-80	289.00
IUUC-Cre-023013	Chlamydomonas reinhardtii	51.68	2.00e-42	164.00
IUUC-Csa-023980	Chlorocebus sabaeus	91.16	2.00e-80	291.00
IUUC-Cho-024703	Choloepus hoffmanni	91.61	2.00e-78	283.00
IUUC-Cin-025346	Ciona intestinalis	55.48	1.00e-49	189.00
IUUC-Csv-026225	Ciona savignyi	53.69	9.00e-44	169.00
IUUC-Cgl-026544	Colletotrichum gloeosporioides	42.06	2.00e-29	122.00
IUUC-Cne-027042	Cryptococcus neoformans	41.67	1.00e-30	125.00
IUUC-Cme-027223	Cyanidioschyzon merolae	47.67	3.00e-21	96.30
IUUC-Dre-027804	Danio rerio	97.96	1.00e-85	308.00
IUUC-Dno-029995	Dasypus novemcinctus	91.16	2.00e-80	291.00
IUUC-Dor-030429	Dipodomys ordii	91.16	7.00e-81	292.00
IUUC-Dse-031499	Dothistroma septosporum	34.97	3.00e-24	105.00
IUUC-Dme-031675	Drosophila melanogaster	55.70	5.00e-48	183.00
IUUC-Ete-032499	Echinops telfairi	91.16	1.00e-80	291.00
IUUC-Eca-034281	Equus caballus	91.16	2.00e-80	291.00
IUUC-Eeu-034913	Erinaceus europaeus	96.47	5.00e-47	179.00
IUUC-Fca-036364	Felis catus	91.16	2.00e-80	291.00
IUUC-Fal-037041	Ficedula albicollis	92.52	2.00e-81	294.00
IUUC-Fox-037777	Fusarium oxysporum	37.31	4.00e-29	122.00
IUUC-Fso-038311	Fusarium solani	39.10	1.00e-28	121.00
IUUC-Gmo-039318	Gadus morhua	93.10	3.00e-62	229.00
IUUC-Ggr-039935	Gaeumannomyces graminis	40.29	1.00e-25	110.00
IUUC-Gga-041006	Gallus gallus	91.84	2.00e-81	294.00
IUUC-Gac-042367	Gasterosteus aculeatus	93.92	8.00e-81	292.00
IUUC-Gma-043650	Glycine max	55.03	3.00e-46	177.00
IUUC-Ggo-045044	Gorilla gorilla	91.16	2.00e-80	291.00
IUUC-Hsa-046971	Homo sapiens	91.16	2.00e-80	291.00
IUUC-Hvu-047485	Hordeum vulgare	55.56	5.00e-12	62.00
IUUC-Itr-048324	Ictidomys tridecemlineatus	97.18	3.00e-38	149.00
IUUC-Kpa-049293	Komagataella pastoris	43.44	1.00e-28	119.00
IUUC-Lch-049462	Latimeria chalumnae	88.44	2.00e-78	283.00
IUUC-Lpe-050846	Leersia perrieri	55.03	1.00e-40	159.00
IUUC-Loc-052857	Lepisosteus oculatus	97.28	1.00e-85	308.00
IUUC-Lma-052974	Leptosphaeria maculans	39.02	1.00e-13	71.20
IUUC-Laf-053536	Loxodonta africana	91.16	2.00e-80	291.00
IUUC-Mcc-054806	Macaca mulatta	91.16	2.00e-80	291.00
IUUC-Meu-056282	Macropus eugenii	88.16	1.00e-37	148.00
IUUC-Mor-057080	Magnaporthe oryzae	40.29	2.00e-25	109.00
IUUC-Mpo-057503	Magnaporthe poae	40.48	3.00e-25	108.00
IUUC-Mtr-057837	Medicago truncatula	57.33	5.00e-47	180.00
IUUC-Mla-059010	Melampsora laricipopulina	46.34	3.00e-26	110.00
IUUC-Mga-059728	Meleagris gallopavo	92.52	2.00e-81	294.00
IUUC-Mvi-060224	Microbotryum violaceum	38.82	4.00e-33	134.00
IUUC-Mdo-062602	Monodelphis domestica	92.52	3.00e-81	293.00
IUUC-Mmu-063528	Mus musculus	91.16	1.00e-80	291.00
IUUC-Mac-065629	Musa acuminata	54.30	2.00e-40	158.00
IUUC-Mpu-066046	Mustela putorius furo	91.16	2.00e-80	291.00
IUUC-Mlu-068107	Myotis lucifugus	91.16	2.00e-80	291.00
IUUC-Nfi-068426	Neosartorya fischeri	40.70	4.00e-14	72.80
IUUC-Ncr-068810	Neurospora crassa	38.89	1.00e-25	110.00
IUUC-Nle-069550	Nomascus leucogenys	91.16	2.00e-80	291.00
IUUC-Opr-071205	Ochotona princeps	91.16	3.00e-80	290.00
IUUC-Ont-071625	Oreochromis niloticus	91.84	9.00e-80	288.00
IUUC-Oan-073396	Ornithorhynchus anatinus	92.52	2.00e-81	294.00
IUUC-Ocu-074136	Oryctolagus cuniculus	90.48	4.00e-80	290.00
IUUC-Oba-075504	Oryza barthii	55.70	6.00e-41	160.00
IUUC-Obr-076300	Oryza brachyantha	56.38	6.00e-43	166.00
IUUC-Ogl-077163	Oryza glaberrima	55.70	6.00e-41	160.00
IUUC-Ogu-078459	Oryza glumaepatula	55.70	6.00e-41	160.00
IUUC-Oin-079095	Oryza indica	48.54	2.00e-37	149.00
IUUC-Olo-080226	Oryza longistaminata	48.54	3.00e-38	154.00
IUUC-Ome-081690	Oryza meridionalis	55.70	6.00e-41	160.00
IUUC-Oni-082984	Oryza nivara	55.70	6.00e-41	160.00
IUUC-Opu-083753	Oryza punctata	56.38	9.00e-46	176.00
IUUC-Oru-084459	Oryza rufipogon	55.70	6.00e-41	160.00
IUUC-Osa-085969	Oryza sativa	55.70	6.00e-41	160.00
IUUC-Ola-087291	Oryzias latipes	93.92	6.00e-81	292.00
IUUC-Olu-087704	Ostreococcus lucimarinus	48.59	2.00e-37	149.00
IUUC-Oga-088086	Otolemur garnettii	91.16	2.00e-80	291.00
IUUC-Oar-089191	Ovis aries	91.16	2.00e-80	291.00
IUUC-Ptr-091583	Pan troglodytes	91.16	2.00e-80	291.00
IUUC-Pan-092440	Papio anubis	91.16	2.00e-80	291.00
IUUC-Psi-093158	Pelodiscus sinensis	92.52	3.00e-81	293.00
IUUC-Pma-094382	Petromyzon marinus	71.05	7.00e-31	124.00
IUUC-Pno-094776	Phaeosphaeria nodorum	37.80	3.00e-13	69.70
IUUC-Ppa-095243	Physcomitrella patens	51.91	4.00e-37	148.00
IUUC-Pfo-096853	Poecilia formosa	93.92	8.00e-81	292.00
IUUC-Pab-098464	Pongo abelii	91.10	1.00e-79	288.00
IUUC-Pop-099055	Populus trichocarpa	54.19	5.00e-42	163.00
IUUC-Pca-100402	Procavia capensis	90.41	1.00e-78	284.00
IUUC-Ppe-101826	Prunus persica	52.98	7.00e-40	156.00
IUUC-Pva-102272	Pteropus vampyrus	91.16	2.00e-80	291.00
IUUC-Pgr-103519	Puccinia graminis	38.46	3.00e-27	114.00
IUUC-Ptt-103904	Puccinia triticina	33.68	3.00e-12	64.30
IUUC-Pte-104017	Pyrenophora teres	40.24	3.00e-14	72.80
IUUC-Pyt-104453	Pyrenophora triticirepentis	40.24	7.00e-14	71.20
IUUC-Rno-105561	Rattus norvegicus	91.16	1.00e-80	291.00
IUUC-Sce-106448	Saccharomyces cerevisiae	35.07	2.00e-20	92.00
IUUC-Sha-106901	Sarcophilus harrisii	92.52	3.00e-81	293.00
IUUC-Sja-107924	Schizosaccharomyces japonicus	43.24	3.00e-35	140.00
IUUC-Spo-108082	Schizosaccharomyces pombe	43.94	1.00e-33	135.00
IUUC-Ssl-108422	Sclerotinia sclerotiorum	44.09	3.00e-29	122.00
IUUC-Smo-109182	Selaginella moellendorffii	56.38	7.00e-47	179.00
IUUC-Sit-110292	Setaria italica	55.03	6.00e-42	163.00
IUUC-Sly-111772	Solanum lycopersicum	54.30	7.00e-38	149.00
IUUC-Stu-112789	Solanum tuberosum	54.97	2.00e-38	151.00
IUUC-Sar-113731	Sorex araneus	74.14	7.00e-46	176.00
IUUC-Sbi-114468	Sorghum bicolor	56.38	9.00e-47	179.00
IUUC-Sre-115201	Sporisorium reilianum	38.64	5.00e-30	124.00
IUUC-Ssc-115318	Sus scrofa	91.16	2.00e-80	291.00
IUUC-Tgu-116782	Taeniopygia guttata	93.20	1.00e-81	295.00
IUUC-Tru-117918	Takifugu rubripes	93.24	2.00e-80	291.00
IUUC-Tni-120731	Tetraodon nigroviridis	93.24	1.00e-80	291.00
IUUC-Tca-121546	Theobroma cacao	54.97	5.00e-41	160.00
IUUC-Tre-122092	Trichoderma reesei	41.60	3.00e-29	120.00
IUUC-Tvi-122416	Trichoderma virens	41.27	7.00e-29	121.00
IUUC-Tae-123195	Triticum aestivum	56.38	3.00e-43	167.00
IUUC-Tur-126519	Triticum urartu	55.03	2.00e-41	161.00
IUUC-Tme-127131	Tuber melanosporum	45.24	9.00e-34	136.00
IUUC-Tbe-128098	Tupaia belangeri	97.18	3.00e-38	149.00
IUUC-Ttr-128765	Tursiops truncatus	77.55	1.00e-65	242.00
IUUC-Uma-129533	Ustilago maydis	35.56	4.00e-27	115.00
IUUC-Vda-129741	Verticillium dahliae	40.48	3.00e-29	122.00
IUUC-Vpa-130667	Vicugna pacos	91.16	2.00e-80	291.00
IUUC-Vvi-131400	Vitis vinifera	54.97	3.00e-45	174.00
IUUC-Xtr-132526	Xenopus tropicalis	90.48	2.00e-79	288.00
IUUC-Xma-133326	Xiphophorus maculatus	93.92	8.00e-81	292.00
IUUC-Yli-134645	Yarrowia lipolytica	44.35	2.00e-33	134.00
IUUC-Zma-134968	Zea mays	57.05	5.00e-44	170.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence