• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
UUCD2 ID IUUC-Xtr-132219
UUCD1 version UUC-XeT-00031
Ensembl Protein ID ENSXETP00000058410.1
UniProt Accession B1H1E4; ARI1_XENTR
Genbank Protein ID AAI60576.1
Protein Name E3 ubiquitin-protein ligase arih1; Protein ariadne-1 homolog; RING-type E3 ubiquitin transferase arih1
Genbank Nucleotide ID BC160576
Gene Name arih1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000032729.1 ENSXETT00000063196.1 ENSXETP00000058410.1
Status
Classification
Family E-Value Score Start End
E3 activity/RBR 9.40e-55 186.2 158 347
Active Site
Position(s) Description Evidence
329 N/A {ECO:0000250|UniProtKB:Q9Y4X5}
Domain Profile

   E3 activity/RBR
   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelk.ikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalk 89
           C++C+l+++++ +t  leC h+fC++C+++yl++k i+eg+ ++iscpa+ c   ++++++++l+++++++ +y++l ++++ve+++ lk
   Q: 158  CQICYLNYPNSYFTG-LECGHKFCMQCWSEYLTTKiIEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLK 246
           **********99985.5**************66652799999************************************************ PP
   S: 90   wcpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnh 179
           wcpapdC++vv ++   +++ v+c kcg++fC++C e+wH++++Ck+lk++ +k++   +++e++++++an+k+CpkC+v+iek++gCnh
   Q: 247  WCPAPDCHHVVKVQYP-DAKPVRC-KCGRQFCFNCGENWHDPVKCKWLKKWIKKCD---DDSETSNWIAANTKECPKCHVTIEKDGGCNH 331
           ***************7.9999999.9******************************...99***************************** PP
   S: 180  mtC..akCkaefCwlC 193
           m C  ++CkaefCw+C
   Q: 332  MVCrnQNCKAEFCWVC 347
           ***9999********* PP
   
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 ube2l3. Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets. The initial ubiquitin is then elongated. E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes.
 E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 ube2l3. Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets. The initial ubiquitin is then elongated. E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes.
Protein Sequence
(Fasta)
MDSDEGYNYE FDDEEECSED SGADEHEDDL ELGEVELVEA GLSGSERAGI CGEGGGSALG 60
PGPGGEEEED YRYEVLTAEQ ILQHMVECIR EVNEVIQNPA TITRILLSHF NWDKEKLMER 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132219|E3,RBR;E3,RING|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCCCCAGTA CCGGAACCGG GGGAGGGGGG GTCGTCCGGG AGCTGAACAC CAAGAACACT 60
TGGAACAGTG CAGCGTGTGC GTGAGGAGGA GGAGCGGTCA CTTGACCCAC GGGGGCGCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132219|E3,RBR;E3,RING|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF01485--IBR
SMART

SM00647--IBR
Gene Ontology

GO:0005737--C:cytoplasm
GO:0097413--C:Lewy body
GO:0016604--C:nuclear body
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG xtr:100144731
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000970 Aegilops tauschii 29.54 3.00e-55 209.00
IUUC-Aml-001385 Ailuropoda melanoleuca 99.13 0.00e+00 921.00
IUUC-Atr-002480 Amborella trichopoda 31.85 4.00e-65 242.00
IUUC-Apl-004184 Anas platyrhynchos 97.51 0.00e+00 871.00
IUUC-Aca-004976 Anolis carolinensis 98.62 0.00e+00 872.00
IUUC-Aly-005807 Arabidopsis lyrata 32.74 6.00e-65 241.00
IUUC-Ath-007166 Arabidopsis thaliana 33.04 4.00e-65 242.00
IUUC-Ago-007926 Ashbya gossypii 29.65 1.00e-55 211.00
IUUC-Acl-008252 Aspergillus clavatus 42.30 3.00e-104 372.00
IUUC-Afl-008468 Aspergillus flavus 42.95 1.00e-105 376.00
IUUC-Afu-009062 Aspergillus fumigatus 44.52 3.00e-106 379.00
IUUC-Ani-009219 Aspergillus nidulans 42.73 3.00e-106 378.00
IUUC-Ang-009538 Aspergillus niger 43.29 3.00e-98 352.00
IUUC-Aor-010009 Aspergillus oryzae 42.95 7.00e-105 374.00
IUUC-Ate-010497 Aspergillus terreus 44.25 2.00e-98 353.00
IUUC-Ame-011264 Astyanax mexicanus 93.80 0.00e+00 976.00
IUUC-Bgr-012016 Blumeria graminis 41.34 3.00e-102 365.00
IUUC-Bta-013518 Bos taurus 99.13 0.00e+00 924.00
IUUC-Bci-013819 Botrytis cinerea 42.46 4.00e-107 381.00
IUUC-Bdi-014685 Brachypodium distachyon 32.81 1.00e-67 250.00
IUUC-Bol-016087 Brassica oleracea 31.94 5.00e-61 228.00
IUUC-Bra-017944 Brassica rapa 33.10 4.00e-56 212.00
IUUC-Cel-018521 Caenorhabditis elegans 55.04 7.00e-138 483.00
IUUC-Cja-019869 Callithrix jacchus 91.58 0.00e+00 830.00
IUUC-Cfa-020812 Canis familiaris 98.91 0.00e+00 918.00
IUUC-Cpo-021627 Cavia porcellus 99.13 0.00e+00 924.00
IUUC-Cre-022815 Chlamydomonas reinhardtii 30.73 5.00e-52 198.00
IUUC-Csa-023034 Chlorocebus sabaeus 99.07 0.00e+00 868.00
IUUC-Cho-024444 Choloepus hoffmanni 96.52 0.00e+00 892.00
IUUC-Cin-025135 Ciona intestinalis 68.91 0.00e+00 681.00
IUUC-Csv-026243 Ciona savignyi 62.78 0.00e+00 665.00
IUUC-Cgl-026434 Colletotrichum gloeosporioides 42.40 9.00e-107 380.00
IUUC-Cne-026861 Cryptococcus neoformans 41.98 2.00e-101 362.00
IUUC-Dre-027785 Danio rerio 94.23 0.00e+00 980.00
IUUC-Dno-029205 Dasypus novemcinctus 99.13 0.00e+00 924.00
IUUC-Dor-030769 Dipodomys ordii 81.25 0.00e+00 717.00
IUUC-Dse-031171 Dothistroma septosporum 42.46 1.00e-104 373.00
IUUC-Dme-031903 Drosophila melanogaster 70.65 0.00e+00 698.00
IUUC-Ete-032929 Echinops telfairi 83.33 2.00e-132 464.00
IUUC-Eca-033431 Equus caballus 98.88 0.00e+00 890.00
IUUC-Eeu-034838 Erinaceus europaeus 85.42 0.00e+00 748.00
IUUC-Fca-035882 Felis catus 95.16 0.00e+00 784.00
IUUC-Fal-037068 Ficedula albicollis 98.65 0.00e+00 889.00
IUUC-Fox-037790 Fusarium oxysporum 50.73 3.00e-77 281.00
IUUC-Fso-038125 Fusarium solani 42.25 2.00e-105 375.00
IUUC-Gmo-038703 Gadus morhua 93.41 0.00e+00 961.00
IUUC-Ggr-039722 Gaeumannomyces graminis 41.76 1.00e-104 373.00
IUUC-Gga-040319 Gallus gallus 99.14 0.00e+00 692.00
IUUC-Gac-041708 Gasterosteus aculeatus 93.40 0.00e+00 949.00
IUUC-Gma-043188 Glycine max 32.81 2.00e-59 223.00
IUUC-Ggo-045178 Gorilla gorilla 99.13 0.00e+00 924.00
IUUC-Hsa-045718 Homo sapiens 99.13 0.00e+00 924.00
IUUC-Hvu-047322 Hordeum vulgare 31.99 3.00e-58 219.00
IUUC-Itr-048934 Ictidomys tridecemlineatus 99.36 5.00e-177 613.00
IUUC-Kpa-049350 Komagataella pastoris 31.73 8.00e-64 237.00
IUUC-Lpe-051110 Leersia perrieri 33.41 2.00e-68 253.00
IUUC-Loc-052442 Lepisosteus oculatus 95.60 0.00e+00 987.00
IUUC-Lma-053253 Leptosphaeria maculans 43.16 4.00e-111 395.00
IUUC-Laf-054351 Loxodonta africana 99.07 0.00e+00 868.00
IUUC-Mcc-054670 Macaca mulatta 95.65 0.00e+00 913.00
IUUC-Meu-056335 Macropus eugenii 91.40 9.00e-142 496.00
IUUC-Mor-057179 Magnaporthe oryzae 42.22 3.00e-105 375.00
IUUC-Mpo-057553 Magnaporthe poae 41.54 1.00e-103 370.00
IUUC-Mtr-058263 Medicago truncatula 31.88 4.00e-58 218.00
IUUC-Mla-058889 Melampsora laricipopulina 36.76 6.00e-78 284.00
IUUC-Mga-059385 Meleagris gallopavo 97.31 0.00e+00 877.00
IUUC-Mvi-060517 Microbotryum violaceum 40.52 2.00e-104 372.00
IUUC-Mmr-061439 Microcebus murinus 92.44 0.00e+00 839.00
IUUC-Mdo-062890 Monodelphis domestica 98.91 0.00e+00 923.00
IUUC-Mmu-063433 Mus musculus 99.13 0.00e+00 924.00
IUUC-Mac-065341 Musa acuminata 33.96 2.00e-64 239.00
IUUC-Mpu-066288 Mustela putorius furo 99.13 0.00e+00 924.00
IUUC-Mlu-067187 Myotis lucifugus 99.13 0.00e+00 919.00
IUUC-Nfi-068339 Neosartorya fischeri 44.30 1.00e-105 377.00
IUUC-Ncr-068947 Neurospora crassa 43.32 2.00e-102 365.00
IUUC-Nle-069263 Nomascus leucogenys 99.13 0.00e+00 924.00
IUUC-Opr-071000 Ochotona princeps 98.83 1.00e-96 346.00
IUUC-Ont-072309 Oreochromis niloticus 93.41 0.00e+00 947.00
IUUC-Oan-073731 Ornithorhynchus anatinus 99.03 0.00e+00 827.00
IUUC-Ocu-074000 Oryctolagus cuniculus 97.29 0.00e+00 871.00
IUUC-Oba-075628 Oryza barthii 32.06 3.00e-62 232.00
IUUC-Obr-076492 Oryza brachyantha 32.96 8.00e-69 254.00
IUUC-Ogl-077447 Oryza glaberrima 33.41 3.00e-69 256.00
IUUC-Ogu-078881 Oryza glumaepatula 33.41 3.00e-69 256.00
IUUC-Oin-079573 Oryza indica 33.41 3.00e-67 249.00
IUUC-Olo-080774 Oryza longistaminata 33.41 7.00e-70 258.00
IUUC-Ome-081275 Oryza meridionalis 32.05 9.00e-62 231.00
IUUC-Oni-082267 Oryza nivara 32.05 9.00e-62 231.00
IUUC-Opu-084135 Oryza punctata 33.41 3.00e-69 256.00
IUUC-Oru-084849 Oryza rufipogon 33.41 4.00e-69 255.00
IUUC-Osa-085435 Oryza sativa 33.41 5.00e-69 255.00
IUUC-Ola-086792 Oryzias latipes 96.96 0.00e+00 942.00
IUUC-Olu-087826 Ostreococcus lucimarinus 32.90 3.00e-50 192.00
IUUC-Oga-088706 Otolemur garnettii 99.13 0.00e+00 924.00
IUUC-Oar-089354 Ovis aries 98.91 0.00e+00 924.00
IUUC-Ptr-091287 Pan troglodytes 99.13 0.00e+00 924.00
IUUC-Pan-091701 Papio anubis 99.07 0.00e+00 867.00
IUUC-Psi-093814 Pelodiscus sinensis 99.07 0.00e+00 868.00
IUUC-Pno-095124 Phaeosphaeria nodorum 35.71 2.00e-78 286.00
IUUC-Ppa-095545 Physcomitrella patens 32.21 3.00e-61 229.00
IUUC-Pfo-096449 Poecilia formosa 92.70 0.00e+00 947.00
IUUC-Pab-098132 Pongo abelii 99.13 0.00e+00 924.00
IUUC-Pop-099139 Populus trichocarpa 32.48 3.00e-64 239.00
IUUC-Pca-100303 Procavia capensis 99.09 0.00e+00 649.00
IUUC-Ppe-101740 Prunus persica 32.74 1.00e-59 224.00
IUUC-Pva-102457 Pteropus vampyrus 99.13 0.00e+00 924.00
IUUC-Pgr-103443 Puccinia graminis 42.53 1.00e-103 370.00
IUUC-Ptt-103795 Puccinia triticina 39.88 1.00e-92 333.00
IUUC-Pte-104022 Pyrenophora teres 41.18 1.00e-101 363.00
IUUC-Pyt-104643 Pyrenophora triticirepentis 42.80 2.00e-109 389.00
IUUC-Rno-106083 Rattus norvegicus 99.13 0.00e+00 924.00
IUUC-Sce-106154 Saccharomyces cerevisiae 29.82 1.00e-64 240.00
IUUC-Sha-106765 Sarcophilus harrisii 96.85 0.00e+00 877.00
IUUC-Sja-107977 Schizosaccharomyces japonicus 43.68 2.00e-98 353.00
IUUC-Spo-108222 Schizosaccharomyces pombe 44.73 1.00e-110 393.00
IUUC-Smo-108845 Selaginella moellendorffii 32.48 4.00e-59 222.00
IUUC-Sit-110348 Setaria italica 32.37 3.00e-65 243.00
IUUC-Sly-111454 Solanum lycopersicum 32.79 2.00e-61 229.00
IUUC-Stu-112533 Solanum tuberosum 32.08 2.00e-59 223.00
IUUC-Sar-113023 Sorex araneus 98.84 0.00e+00 862.00
IUUC-Sbi-114262 Sorghum bicolor 33.04 1.00e-66 247.00
IUUC-Sre-115120 Sporisorium reilianum 43.83 7.00e-110 390.00
IUUC-Ssc-115667 Sus scrofa 88.92 1.00e-180 625.00
IUUC-Tgu-117273 Taeniopygia guttata 98.62 0.00e+00 868.00
IUUC-Tru-118338 Takifugu rubripes 91.39 0.00e+00 950.00
IUUC-Tsy-119096 Tarsius syrichta 90.74 0.00e+00 773.00
IUUC-Tni-120238 Tetraodon nigroviridis 91.90 0.00e+00 946.00
IUUC-Tca-121037 Theobroma cacao 33.11 3.00e-66 245.00
IUUC-Tre-121902 Trichoderma reesei 42.11 6.00e-103 367.00
IUUC-Tvi-122474 Trichoderma virens 41.19 2.00e-103 369.00
IUUC-Tae-124132 Triticum aestivum 33.33 4.00e-68 252.00
IUUC-Tur-126320 Triticum urartu 30.99 1.00e-55 210.00
IUUC-Tme-127089 Tuber melanosporum 42.92 1.00e-103 370.00
IUUC-Tbe-127409 Tupaia belangeri 92.17 4.00e-121 427.00
IUUC-Ttr-128909 Tursiops truncatus 89.98 0.00e+00 809.00
IUUC-Uma-129487 Ustilago maydis 42.49 2.00e-110 392.00
IUUC-Vda-129939 Verticillium dahliae 41.97 7.00e-105 374.00
IUUC-Vpa-130259 Vicugna pacos 95.87 0.00e+00 882.00
IUUC-Vvi-131463 Vitis vinifera 32.29 2.00e-58 220.00
IUUC-Xma-133423 Xiphophorus maculatus 92.70 0.00e+00 947.00
IUUC-Yli-134622 Yarrowia lipolytica 35.65 3.00e-73 268.00
IUUC-Zma-135131 Zea mays 33.33 3.00e-67 249.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved