iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055146

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase RNF128

Genbank Nucleotide ID

JSUE03046441

Gene Name

RNF128; EGK_20792

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021412.3	ENSMMUT00000030141.3	ENSMMUP00000028207.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.66	0.00e+00	812.00	IUUC-Hsa-046745
E3 activity/RING/RING	96.26	0.00e+00	803.00	IUUC-Mmu-064235

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MGPPPRAGVS CRGGCGSSRL LAWCFLLALS PQAPGSRGAE AVWTAYLNVS WRVPHTGVNR 60
TVWELSEEGV YGQDSPLEPV SGVLVPPDGP GALNACNPHT NFTVPTVWGS TVQVSWLALI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGTAGCTG AGAGCGCTGG AGCTTCGAGG AGCTGCATCT GCGGCAACCT GTGTGCTGAC 60
GCTACGTGCC TCCTGGCTCC GACCTAGCTC GCAGCTCCCC AGTCTCACTC CATTCCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0005770--C:late endosome
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042036--P:negative regulation of cytokine biosynthetic process
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000408	Aegilops tauschii	48.21	2.00e-12	66.20
IUUC-Aml-001674	Ailuropoda melanoleuca	96.75	0.00e+00	832.00
IUUC-Apl-003776	Anas platyrhynchos	67.22	5.00e-108	384.00
IUUC-Aca-004318	Anolis carolinensis	69.07	8.00e-119	420.00
IUUC-Ame-011286	Astyanax mexicanus	46.44	2.00e-84	306.00
IUUC-Bta-013454	Bos taurus	94.66	0.00e+00	816.00
IUUC-Bci-013726	Botrytis cinerea	54.00	1.00e-12	68.20
IUUC-Cja-019864	Callithrix jacchus	99.07	0.00e+00	850.00
IUUC-Cfa-020185	Canis familiaris	96.52	0.00e+00	827.00
IUUC-Cpo-022417	Cavia porcellus	53.87	6.00e-87	313.00
IUUC-Csa-023224	Chlorocebus sabaeus	99.53	0.00e+00	824.00
IUUC-Cho-024710	Choloepus hoffmanni	80.40	8.00e-148	516.00
IUUC-Cne-026951	Cryptococcus neoformans	34.69	7.00e-11	61.60
IUUC-Dre-028249	Danio rerio	53.02	2.00e-89	322.00
IUUC-Dno-029216	Dasypus novemcinctus	95.94	4.00e-136	477.00
IUUC-Dor-030487	Dipodomys ordii	83.50	0.00e+00	670.00
IUUC-Dse-031357	Dothistroma septosporum	45.21	1.00e-12	67.40
IUUC-Ete-032376	Echinops telfairi	96.39	4.00e-138	483.00
IUUC-Eca-034264	Equus caballus	96.52	0.00e+00	829.00
IUUC-Eeu-034606	Erinaceus europaeus	92.13	5.00e-128	451.00
IUUC-Fca-036503	Felis catus	96.52	0.00e+00	828.00
IUUC-Fal-036671	Ficedula albicollis	60.59	1.00e-112	400.00
IUUC-Gmo-039483	Gadus morhua	47.94	6.00e-82	297.00
IUUC-Gga-040248	Gallus gallus	67.40	2.00e-133	468.00
IUUC-Ggo-045319	Gorilla gorilla	51.37	2.00e-92	332.00
IUUC-Hsa-046745	Homo sapiens	97.66	0.00e+00	839.00
IUUC-Itr-048362	Ictidomys tridecemlineatus	97.20	0.00e+00	836.00
IUUC-Kpa-049143	Komagataella pastoris	49.02	3.00e-11	63.20
IUUC-Lch-050549	Latimeria chalumnae	57.53	3.00e-121	428.00
IUUC-Loc-051929	Lepisosteus oculatus	56.25	6.00e-97	347.00
IUUC-Laf-054197	Loxodonta africana	95.13	0.00e+00	790.00
IUUC-Meu-056649	Macropus eugenii	75.98	1.00e-163	568.00
IUUC-Mtr-057787	Medicago truncatula	47.17	3.00e-11	62.00
IUUC-Mga-059520	Meleagris gallopavo	66.49	2.00e-133	468.00
IUUC-Mmr-061502	Microcebus murinus	96.96	0.00e+00	805.00
IUUC-Mdo-062875	Monodelphis domestica	65.21	7.00e-124	437.00
IUUC-Mmu-064235	Mus musculus	96.26	0.00e+00	829.00
IUUC-Mpu-066452	Mustela putorius furo	91.52	9.00e-171	592.00
IUUC-Mlu-067189	Myotis lucifugus	95.13	0.00e+00	803.00
IUUC-Nle-070026	Nomascus leucogenys	98.60	0.00e+00	820.00
IUUC-Opr-070435	Ochotona princeps	72.18	1.00e-96	345.00
IUUC-Oan-073238	Ornithorhynchus anatinus	74.83	2.00e-117	415.00
IUUC-Ocu-074960	Oryctolagus cuniculus	96.73	0.00e+00	795.00
IUUC-Ola-086348	Oryzias latipes	47.39	7.00e-78	283.00
IUUC-Oga-088543	Otolemur garnettii	95.33	0.00e+00	822.00
IUUC-Oar-089599	Ovis aries	94.66	0.00e+00	815.00
IUUC-Ptr-091576	Pan troglodytes	94.04	1.00e-171	595.00
IUUC-Pan-091690	Papio anubis	99.77	0.00e+00	825.00
IUUC-Psi-093642	Pelodiscus sinensis	76.69	4.00e-105	374.00
IUUC-Pfo-096270	Poecilia formosa	45.95	4.00e-77	281.00
IUUC-Pab-097965	Pongo abelii	98.13	0.00e+00	814.00
IUUC-Pva-102991	Pteropus vampyrus	84.97	4.00e-175	607.00
IUUC-Rno-105667	Rattus norvegicus	96.26	0.00e+00	831.00
IUUC-Sha-107293	Sarcophilus harrisii	77.48	8.00e-156	543.00
IUUC-Ssl-108451	Sclerotinia sclerotiorum	54.00	1.00e-12	67.80
IUUC-Sar-113682	Sorex araneus	95.86	6.00e-144	502.00
IUUC-Ssc-115583	Sus scrofa	96.52	0.00e+00	827.00
IUUC-Tgu-117406	Taeniopygia guttata	58.33	1.00e-81	296.00
IUUC-Tru-118147	Takifugu rubripes	46.08	9.00e-74	270.00
IUUC-Tsy-118918	Tarsius syrichta	95.79	0.00e+00	772.00
IUUC-Tni-120865	Tetraodon nigroviridis	46.15	4.00e-69	254.00
IUUC-Tbe-127498	Tupaia belangeri	53.33	9.00e-107	380.00
IUUC-Ttr-128640	Tursiops truncatus	96.52	0.00e+00	803.00
IUUC-Vpa-130536	Vicugna pacos	88.19	0.00e+00	733.00
IUUC-Xma-133114	Xiphophorus maculatus	48.47	2.00e-78	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence