iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003975

Ensembl Protein ID

ENSAPLP00000006821.1

UniProt Accession

U3IHU9; U3IHU9_ANAPL

Genbank Protein ID

ENSAPLP00000006821

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

ADON01142523

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000007171.1	ENSAPLT00000007471.1	ENSAPLP00000006821.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-07	30.9	202	227

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 12   sd..tllvsGsdDgtikvWDlrtgvl 35
           ++  +ll+s+s+Dgt+++W +++g+ 
   Q: 202  PNypDLLLSASGDGTLRLWHYKSGDE 227
           333589**************999976 PP

Organism

Anas platyrhynchos

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

LISIKLVAPC KACLYVWFCS GGFTLLFFFF TRREGDLFVY DCSDAEQKAV EEKRQDGQPT 60
DKGSDDILAF AFSPSGDYFV LTDDNKRLIL FRTKPSWECI SIRSVNRRCT SLVITAAEDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTATTTCCA TCAAGCTCGT GGCACCTTGC AAAGCCTGTC TATATGTTAG GACAAACACA 60
ATGACAACTC CTCGAGCCTG CTCAAGCACG ACAGCAGCTC ACACATGAAG GGGAAGGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	26.34	1.00e-09	57.40
IUUC-Aca-005170	Anolis carolinensis	67.48	3.00e-127	447.00
IUUC-Aly-005769	Arabidopsis lyrata	32.13	2.00e-28	119.00
IUUC-Ath-006733	Arabidopsis thaliana	31.05	6.00e-27	114.00
IUUC-Acl-008151	Aspergillus clavatus	26.48	5.00e-12	65.50
IUUC-Afl-008518	Aspergillus flavus	44.09	2.00e-12	66.20
IUUC-Afu-009102	Aspergillus fumigatus	29.75	2.00e-12	67.00
IUUC-Ani-009442	Aspergillus nidulans	26.94	9.00e-13	67.80
IUUC-Aor-010133	Aspergillus oryzae	28.19	6.00e-15	75.10
IUUC-Ate-010465	Aspergillus terreus	28.70	1.00e-13	70.90
IUUC-Ame-010613	Astyanax mexicanus	44.33	4.00e-91	327.00
IUUC-Bgr-012067	Blumeria graminis	39.53	2.00e-14	73.60
IUUC-Bta-012788	Bos taurus	58.89	1.00e-120	425.00
IUUC-Bdi-014458	Brachypodium distachyon	31.05	1.00e-18	87.40
IUUC-Bol-016398	Brassica oleracea	32.92	2.00e-26	112.00
IUUC-Bra-016644	Brassica rapa	36.32	9.00e-24	105.00
IUUC-Cpo-021963	Cavia porcellus	58.33	3.00e-117	414.00
IUUC-Csa-024148	Chlorocebus sabaeus	60.18	2.00e-105	375.00
IUUC-Cne-026834	Cryptococcus neoformans	38.46	4.00e-18	85.90
IUUC-Dre-028427	Danio rerio	45.80	9.00e-95	340.00
IUUC-Dno-028881	Dasypus novemcinctus	51.73	1.00e-110	392.00
IUUC-Dor-030522	Dipodomys ordii	58.21	4.00e-121	427.00
IUUC-Dme-032136	Drosophila melanogaster	41.07	1.00e-25	110.00
IUUC-Fca-035833	Felis catus	59.40	2.00e-126	444.00
IUUC-Fal-037497	Ficedula albicollis	82.07	3.00e-171	593.00
IUUC-Gga-040547	Gallus gallus	84.74	0.00e+00	629.00
IUUC-Gac-041761	Gasterosteus aculeatus	44.02	4.00e-80	291.00
IUUC-Gma-043722	Glycine max	31.16	7.00e-24	104.00
IUUC-Ggo-045340	Gorilla gorilla	59.59	1.00e-111	395.00
IUUC-Hsa-046403	Homo sapiens	60.18	1.00e-112	399.00
IUUC-Hvu-047643	Hordeum vulgare	29.28	6.00e-20	91.70
IUUC-Itr-048103	Ictidomys tridecemlineatus	58.70	1.00e-121	429.00
IUUC-Kpa-049283	Komagataella pastoris	30.93	4.00e-19	88.60
IUUC-Lch-050682	Latimeria chalumnae	58.45	4.00e-119	421.00
IUUC-Lpe-050712	Leersia perrieri	29.51	3.00e-24	105.00
IUUC-Loc-052599	Lepisosteus oculatus	54.62	5.00e-113	400.00
IUUC-Laf-054390	Loxodonta africana	59.73	5.00e-125	440.00
IUUC-Mcc-054747	Macaca mulatta	60.47	1.00e-113	402.00
IUUC-Mtr-058600	Medicago truncatula	33.33	6.00e-28	117.00
IUUC-Mla-059129	Melampsora laricipopulina	26.99	6.00e-12	64.30
IUUC-Mga-059876	Meleagris gallopavo	85.83	0.00e+00	633.00
IUUC-Mvi-060359	Microbotryum violaceum	31.06	1.00e-11	64.70
IUUC-Mmr-061518	Microcebus murinus	58.77	6.00e-119	420.00
IUUC-Mac-065625	Musa acuminata	30.65	3.00e-22	99.40
IUUC-Nfi-068402	Neosartorya fischeri	28.40	1.00e-11	64.30
IUUC-Nle-069914	Nomascus leucogenys	58.11	2.00e-106	378.00
IUUC-Ont-071555	Oreochromis niloticus	46.74	5.00e-84	304.00
IUUC-Oan-072951	Ornithorhynchus anatinus	61.08	3.00e-132	464.00
IUUC-Ocu-074679	Oryctolagus cuniculus	58.31	3.00e-116	411.00
IUUC-Oba-075355	Oryza barthii	28.51	2.00e-15	77.00
IUUC-Obr-076769	Oryza brachyantha	32.93	2.00e-25	109.00
IUUC-Ogl-077168	Oryza glaberrima	30.91	6.00e-26	111.00
IUUC-Ogu-078275	Oryza glumaepatula	28.10	3.00e-15	76.30
IUUC-Oin-079207	Oryza indica	30.91	6.00e-26	111.00
IUUC-Oni-082437	Oryza nivara	26.55	1.00e-14	73.90
IUUC-Opu-084031	Oryza punctata	30.91	3.00e-24	105.00
IUUC-Oru-084380	Oryza rufipogon	28.10	7.00e-15	75.10
IUUC-Osa-085327	Oryza sativa	30.55	4.00e-25	108.00
IUUC-Ola-086716	Oryzias latipes	40.69	5.00e-71	261.00
IUUC-Olu-087708	Ostreococcus lucimarinus	26.50	4.00e-15	75.50
IUUC-Oar-090239	Ovis aries	58.89	2.00e-122	431.00
IUUC-Ptr-090851	Pan troglodytes	59.59	5.00e-112	397.00
IUUC-Pan-092558	Papio anubis	60.12	1.00e-104	372.00
IUUC-Psi-093792	Pelodiscus sinensis	75.29	1.00e-158	551.00
IUUC-Ppa-095757	Physcomitrella patens	37.78	5.00e-20	92.00
IUUC-Pfo-096465	Poecilia formosa	43.57	3.00e-87	314.00
IUUC-Pab-097722	Pongo abelii	58.65	9.00e-116	409.00
IUUC-Pop-098979	Populus trichocarpa	34.76	2.00e-18	86.30
IUUC-Pca-100753	Procavia capensis	57.35	5.00e-88	317.00
IUUC-Ppe-101515	Prunus persica	30.36	9.00e-20	90.90
IUUC-Sja-107780	Schizosaccharomyces japonicus	28.72	5.00e-13	68.60
IUUC-Spo-108251	Schizosaccharomyces pombe	29.84	5.00e-11	61.60
IUUC-Smo-108938	Selaginella moellendorffii	35.35	2.00e-19	90.10
IUUC-Sit-110020	Setaria italica	31.33	1.00e-22	100.00
IUUC-Sly-111543	Solanum lycopersicum	27.89	2.00e-23	103.00
IUUC-Stu-111925	Solanum tuberosum	27.30	4.00e-22	98.60
IUUC-Sbi-114061	Sorghum bicolor	32.02	6.00e-25	108.00
IUUC-Tgu-117321	Taeniopygia guttata	81.42	8.00e-160	555.00
IUUC-Tru-118454	Takifugu rubripes	45.48	2.00e-82	298.00
IUUC-Tni-119894	Tetraodon nigroviridis	42.90	4.00e-75	274.00
IUUC-Tca-121746	Theobroma cacao	32.74	2.00e-21	96.30
IUUC-Tae-124459	Triticum aestivum	29.71	3.00e-20	92.40
IUUC-Tur-126254	Triticum urartu	25.00	7.00e-12	64.30
IUUC-Tbe-127683	Tupaia belangeri	70.24	3.00e-32	132.00
IUUC-Ttr-129056	Tursiops truncatus	57.18	1.00e-115	409.00
IUUC-Vvi-131428	Vitis vinifera	31.17	1.00e-21	97.10
IUUC-Xma-133605	Xiphophorus maculatus	44.92	2.00e-89	322.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence