iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054170

Ensembl Protein ID

ENSLAFP00000024936.1

UniProt Accession

G3UAS8; G3UAS8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

NACC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000004000.2	ENSLAFT00000028522.1	ENSLAFP00000024936.1
ENSLAFG00000004000.2	ENSLAFT00000004000.2	ENSLAFP00000003338.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.60e-16	58.6	30	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv +vv+g+ f+ah++vLaasS +F++lf+++     sk+  e+ + v p +f+++l+F+Ytgkl++
   Q: 30   CDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGN-----SKSAFELPGtVPPACFQQILSFCYTGKLTM 92
           8*****************************774.....46778***88*****************986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS 60
GNSKSAFELP GTVPPACFQQ ILSFCYTGKL TMAASEQLVV MYTAGFLQIQ HIVERGTDLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGA TGCTGCATAT CGAGATCCCC AACTTTGGGA ACACTGTGCT GGGCTGCCTG 60
AACGAGCAGC GCCTCCTGGG CCTCTACTGC GATGTGTCCA TCGTGGTCAA GGGCCAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018379--BEN_domain
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS51457--BEN
PS50097--BTB

Pfam

PF10523--BEN
PF00651--BTB

SMART

SM01025--BEN
SM00225--BTB

Gene Ontology

GO:0005739--C:mitochondrion
GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0016581--C:NuRD complex
GO:0004407--F:histone deacetylase activity
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076--F:transcription factor activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0034629--P:cellular protein complex localization
GO:0008285--P:negative regulation of cell proliferation
GO:1900477--P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001902	Ailuropoda melanoleuca	85.71	0.00e+00	763.00
IUUC-Apl-004203	Anas platyrhynchos	77.40	0.00e+00	886.00
IUUC-Ame-011263	Astyanax mexicanus	50.64	4.00e-74	272.00
IUUC-Bta-012908	Bos taurus	89.96	0.00e+00	891.00
IUUC-Cja-019140	Callithrix jacchus	87.39	0.00e+00	951.00
IUUC-Cfa-020493	Canis familiaris	83.85	2.00e-146	511.00
IUUC-Cpo-022399	Cavia porcellus	86.81	0.00e+00	962.00
IUUC-Csa-024135	Chlorocebus sabaeus	85.91	0.00e+00	929.00
IUUC-Dre-027761	Danio rerio	60.00	2.00e-72	266.00
IUUC-Dno-029271	Dasypus novemcinctus	76.65	0.00e+00	731.00
IUUC-Ete-032427	Echinops telfairi	85.16	0.00e+00	879.00
IUUC-Eca-033986	Equus caballus	87.54	0.00e+00	947.00
IUUC-Eeu-035211	Erinaceus europaeus	86.20	0.00e+00	933.00
IUUC-Fca-035733	Felis catus	86.07	0.00e+00	825.00
IUUC-Fal-037348	Ficedula albicollis	79.83	0.00e+00	892.00
IUUC-Fox-037719	Fusarium oxysporum	32.84	2.00e-07	50.10
IUUC-Gmo-039529	Gadus morhua	72.73	3.00e-78	285.00
IUUC-Gga-040405	Gallus gallus	80.10	0.00e+00	915.00
IUUC-Gac-041308	Gasterosteus aculeatus	63.21	2.00e-157	548.00
IUUC-Ggo-044687	Gorilla gorilla	69.08	0.00e+00	693.00
IUUC-Hsa-045955	Homo sapiens	87.86	0.00e+00	914.00
IUUC-Itr-048872	Ictidomys tridecemlineatus	89.17	0.00e+00	927.00
IUUC-Lch-049615	Latimeria chalumnae	71.95	0.00e+00	835.00
IUUC-Loc-051881	Lepisosteus oculatus	66.15	0.00e+00	640.00
IUUC-Lma-053325	Leptosphaeria maculans	36.84	8.00e-07	47.40
IUUC-Mga-059627	Meleagris gallopavo	79.76	0.00e+00	908.00
IUUC-Mdo-063014	Monodelphis domestica	81.56	8.00e-159	553.00
IUUC-Mmu-063897	Mus musculus	86.24	0.00e+00	971.00
IUUC-Mpu-066806	Mustela putorius furo	86.41	0.00e+00	848.00
IUUC-Nle-069114	Nomascus leucogenys	85.09	0.00e+00	832.00
IUUC-Opr-071127	Ochotona princeps	95.35	6.00e-72	265.00
IUUC-Ont-071693	Oreochromis niloticus	71.74	2.00e-90	326.00
IUUC-Oan-073510	Ornithorhynchus anatinus	82.55	0.00e+00	936.00
IUUC-Ola-086572	Oryzias latipes	60.93	9.00e-168	583.00
IUUC-Oga-088653	Otolemur garnettii	85.21	0.00e+00	932.00
IUUC-Oar-089811	Ovis aries	86.33	0.00e+00	741.00
IUUC-Ptr-090703	Pan troglodytes	89.27	0.00e+00	904.00
IUUC-Pan-092388	Papio anubis	87.17	0.00e+00	937.00
IUUC-Psi-093786	Pelodiscus sinensis	80.44	0.00e+00	921.00
IUUC-Pno-095029	Phaeosphaeria nodorum	29.11	1.00e-05	43.10
IUUC-Pfo-096554	Poecilia formosa	59.40	5.00e-163	567.00
IUUC-Pca-101090	Procavia capensis	90.91	0.00e+00	944.00
IUUC-Ppe-101171	Prunus persica	39.19	3.00e-06	47.00
IUUC-Pva-102843	Pteropus vampyrus	85.19	0.00e+00	905.00
IUUC-Rno-105139	Rattus norvegicus	85.91	0.00e+00	969.00
IUUC-Sha-107545	Sarcophilus harrisii	83.00	0.00e+00	931.00
IUUC-Tgu-117401	Taeniopygia guttata	79.93	0.00e+00	903.00
IUUC-Tru-118080	Takifugu rubripes	63.83	6.00e-151	526.00
IUUC-Tni-120321	Tetraodon nigroviridis	60.42	2.00e-153	535.00
IUUC-Ttr-128369	Tursiops truncatus	88.15	0.00e+00	662.00
IUUC-Xtr-131793	Xenopus tropicalis	75.98	7.00e-157	546.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence