iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011954

Ensembl Protein ID

ENSAMXP00000003172.1

UniProt Accession

W5K6G1; W5K6G1_ASTMX

Genbank Protein ID

ENSAMXP00000003172

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01091316

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002975.1	ENSAMXT00000003172.1	ENSAMXP00000003172.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.10e-15	55.2	58	112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +  ++lydye+ +d++L +kkGd+++++   +++++W+++ +  +gk+G++P+n+v+k
   Q: 58   NIAIALYDYEGLHDGDLGFKKGDKLKIL---QESGEWWRAMSLSSGKEGFIPSNYVAK 112
           67799***********************...99***********************86 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGCVGTKPEQ DSGGKAVGGD DSGNRGQTAH YVKDPTTGTK ANRTVSSPPP SNTDGGENIA 60
IALYDYEGLH DGDLGFKKGD KLKILQESGE WWRAMSLSSG KEGFIPSNYV AKDTLQTEDW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTGTAGAG GGGGGGAACA GGCGGATGTT CGTGACTCGG CGCAGATGAT TGCCCTCGGC 60
CTCAGTAGCC GCTTAACTTC CTCTTCAGCA GCTCGCTCTC ACTGTACATC TTCTCACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	75.00	0.00e+00	789.00
IUUC-Apl-003285	Anas platyrhynchos	74.80	0.00e+00	789.00
IUUC-Aca-004724	Anolis carolinensis	74.85	0.00e+00	769.00
IUUC-Bta-013060	Bos taurus	75.89	0.00e+00	800.00
IUUC-Cja-019817	Callithrix jacchus	74.36	0.00e+00	785.00
IUUC-Cfa-020511	Canis familiaris	75.49	0.00e+00	794.00
IUUC-Cpo-022538	Cavia porcellus	75.30	0.00e+00	792.00
IUUC-Csa-024143	Chlorocebus sabaeus	75.49	0.00e+00	795.00
IUUC-Dre-028157	Danio rerio	89.26	0.00e+00	947.00
IUUC-Dno-029761	Dasypus novemcinctus	75.10	0.00e+00	804.00
IUUC-Dor-030892	Dipodomys ordii	65.67	0.00e+00	684.00
IUUC-Eca-034090	Equus caballus	74.70	0.00e+00	780.00
IUUC-Fca-035937	Felis catus	74.31	0.00e+00	757.00
IUUC-Fal-036624	Ficedula albicollis	74.46	0.00e+00	791.00
IUUC-Gmo-039009	Gadus morhua	80.52	0.00e+00	849.00
IUUC-Gga-040296	Gallus gallus	72.17	0.00e+00	769.00
IUUC-Gac-042362	Gasterosteus aculeatus	83.79	0.00e+00	882.00
IUUC-Ggo-044570	Gorilla gorilla	75.35	0.00e+00	794.00
IUUC-Hsa-046378	Homo sapiens	75.74	0.00e+00	799.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	74.11	0.00e+00	786.00
IUUC-Loc-052904	Lepisosteus oculatus	84.42	0.00e+00	906.00
IUUC-Laf-053654	Loxodonta africana	75.35	0.00e+00	796.00
IUUC-Mcc-055317	Macaca mulatta	75.69	0.00e+00	801.00
IUUC-Meu-056879	Macropus eugenii	69.48	0.00e+00	676.00
IUUC-Mga-060194	Meleagris gallopavo	76.12	0.00e+00	734.00
IUUC-Mmr-061510	Microcebus murinus	75.35	0.00e+00	791.00
IUUC-Mdo-062035	Monodelphis domestica	74.41	0.00e+00	790.00
IUUC-Mmu-064037	Mus musculus	74.70	0.00e+00	790.00
IUUC-Mpu-066874	Mustela putorius furo	75.35	0.00e+00	791.00
IUUC-Mlu-068202	Myotis lucifugus	72.53	0.00e+00	760.00
IUUC-Nle-069222	Nomascus leucogenys	76.09	0.00e+00	797.00
IUUC-Opr-070705	Ochotona princeps	74.95	0.00e+00	787.00
IUUC-Ont-072347	Oreochromis niloticus	90.83	0.00e+00	845.00
IUUC-Ocu-074490	Oryctolagus cuniculus	74.11	0.00e+00	785.00
IUUC-Ola-086521	Oryzias latipes	89.51	0.00e+00	863.00
IUUC-Oga-088153	Otolemur garnettii	75.10	0.00e+00	794.00
IUUC-Oar-090184	Ovis aries	75.25	0.00e+00	791.00
IUUC-Ptr-090505	Pan troglodytes	71.79	0.00e+00	743.00
IUUC-Pan-092260	Papio anubis	75.69	0.00e+00	801.00
IUUC-Pma-094311	Petromyzon marinus	73.26	0.00e+00	707.00
IUUC-Pfo-096566	Poecilia formosa	85.60	0.00e+00	918.00
IUUC-Pva-103021	Pteropus vampyrus	76.33	0.00e+00	799.00
IUUC-Rno-105309	Rattus norvegicus	74.11	0.00e+00	788.00
IUUC-Sha-107099	Sarcophilus harrisii	73.19	0.00e+00	777.00
IUUC-Ssc-115624	Sus scrofa	69.34	0.00e+00	690.00
IUUC-Tgu-116912	Taeniopygia guttata	74.46	0.00e+00	785.00
IUUC-Tru-118449	Takifugu rubripes	86.97	0.00e+00	825.00
IUUC-Tbe-128144	Tupaia belangeri	72.65	0.00e+00	679.00
IUUC-Xtr-132224	Xenopus tropicalis	66.88	0.00e+00	687.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence