iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086943

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04070646

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000001926.1	ENSORLT00000002404.1	ENSORLP00000002403.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-55	181.9	39	78
UBD/Beta-Prp	2.00e-130	434.7	656	914

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           gHt ++ cl f  d  +l+s + D  +t+ +W++r+g+ l
   Q: 39   GHTHGIACLTFsADgQRLASVGLDakNTVCIWEWRRGKIL 78
           8***********5569******9999**********9987 PP

UBD/Beta-Prp

   S: 46   rsl.sgheaevtavkfspdgkilvtg..seDrtikvwdlstgkcvhtlkg.hedsvlslsfspsgdklvs..Gshdrtirvwdletgqc 128
           +++  gh++ + +++++p +++ +tg  ++D +i+vwd++t kc++ lkg h++ v++l+fs++g++lvs   ++d  i +wd++ g++
   Q: 656  QRFyLGHDDDILSLSIHPLKDFAATGqvGRDPAIHVWDIQTLKCLSLLKGfHQRGVCALDFSADGKSLVSvgLDDDHSIILWDWKRGEK 744
           455589***************9998733689******************769999***********999944478899999******** PP
   S: 129  leetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl....tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtg 212
           l  t +gh++ + +v+ +p   + lv+ +  + +++W+ + g l+ +     ++g ++   s+ + +n   + sg+  g+v +w   + 
   Q: 745  LA-TARGHKEKIFVVKCNPMLmDKLVTVGI-KHIKFWQHAGGGLIFKRgafrSSGRHETMMSVCYGRNEALVFSGAATGDVYIWK--EP 829
           *9.****************99988888877.679*****9999999888887555777777788********************5..69 PP
   S: 213  ecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn...............ssvisvavlsfgdnvlvlgsed 286
             ++t+++h+ +v  +  +  d+ +v+g++Dg++ +Wd   + +lkt++ ++                s+ +   + +g+ +++ g+++
   Q: 830  LLLKTVKAHDGPVFAMFSL--DKGFVTGGKDGVVALWDDMFDRCLKTYAIKRaalspaskglllednPSIRA---ITLGHGHILVGTKN 913
           99***********988888..9****************999*****99988866666666666643222222...23466666666666 PP
   S: 287  s 287
           +
   Q: 914  G 914
           5 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

SLALHPERSL VATGQVGKDP YVCVWDSFTV QTVSLLRDGH THGIACLTFS ADGQRLASVG 60
LDAKNTVCIW EWRRGKILAS ATGHSDRIFD ICWDPFQQDR LVSCGVKHIK FWALCGNALT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCTGGCCT TGCATCCAGA GCGTTCCCTG GTGGCGACGG GTCAGGTGGG GAAGGATCCT 60
TACGTGTGCG TCTGGGACTC CTTCACCGTC CAGACCGTGT CTCTGCTGCG GGATGGACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	79.07	0.00e+00	3120.00
IUUC-Apl-003604	Anas platyrhynchos	78.32	0.00e+00	3068.00
IUUC-Aca-004572	Anolis carolinensis	75.71	0.00e+00	3006.00
IUUC-Ame-010713	Astyanax mexicanus	75.40	0.00e+00	2981.00
IUUC-Bta-012812	Bos taurus	78.80	0.00e+00	3109.00
IUUC-Cja-019191	Callithrix jacchus	78.65	0.00e+00	3106.00
IUUC-Cfa-020041	Canis familiaris	79.10	0.00e+00	2891.00
IUUC-Csa-023689	Chlorocebus sabaeus	78.27	0.00e+00	3094.00
IUUC-Cho-025038	Choloepus hoffmanni	77.55	0.00e+00	1219.00
IUUC-Dno-029982	Dasypus novemcinctus	77.62	0.00e+00	3060.00
IUUC-Eca-034161	Equus caballus	77.37	0.00e+00	3046.00
IUUC-Eeu-035180	Erinaceus europaeus	57.60	0.00e+00	1114.00
IUUC-Fca-036307	Felis catus	79.17	0.00e+00	3121.00
IUUC-Fal-037332	Ficedula albicollis	78.20	0.00e+00	3067.00
IUUC-Gmo-039057	Gadus morhua	72.19	0.00e+00	2790.00
IUUC-Gac-042040	Gasterosteus aculeatus	85.10	0.00e+00	3164.00
IUUC-Ggo-045107	Gorilla gorilla	78.75	0.00e+00	3107.00
IUUC-Hsa-046482	Homo sapiens	78.91	0.00e+00	3108.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	77.34	0.00e+00	3099.00
IUUC-Loc-052642	Lepisosteus oculatus	81.33	0.00e+00	3178.00
IUUC-Laf-053649	Loxodonta africana	78.69	0.00e+00	3069.00
IUUC-Mga-059202	Meleagris gallopavo	77.90	0.00e+00	3079.00
IUUC-Mmr-060729	Microcebus murinus	78.66	0.00e+00	3105.00
IUUC-Mdo-062462	Monodelphis domestica	78.75	0.00e+00	3112.00
IUUC-Mmu-063865	Mus musculus	78.28	0.00e+00	3121.00
IUUC-Mpu-066724	Mustela putorius furo	78.91	0.00e+00	3116.00
IUUC-Mlu-067816	Myotis lucifugus	78.78	0.00e+00	3109.00
IUUC-Opr-070213	Ochotona princeps	77.60	0.00e+00	1682.00
IUUC-Ont-071928	Oreochromis niloticus	89.77	0.00e+00	3486.00
IUUC-Oan-073563	Ornithorhynchus anatinus	78.40	0.00e+00	3087.00
IUUC-Ocu-074531	Oryctolagus cuniculus	79.01	0.00e+00	3118.00
IUUC-Olu-087860	Ostreococcus lucimarinus	38.63	1.00e-118	420.00
IUUC-Oga-088665	Otolemur garnettii	78.33	0.00e+00	3085.00
IUUC-Oar-090429	Ovis aries	79.01	0.00e+00	3118.00
IUUC-Psi-093281	Pelodiscus sinensis	77.43	0.00e+00	3014.00
IUUC-Pma-094424	Petromyzon marinus	66.32	1.00e-117	415.00
IUUC-Pfo-096687	Poecilia formosa	83.39	0.00e+00	3174.00
IUUC-Rno-105002	Rattus norvegicus	78.49	0.00e+00	3134.00
IUUC-Sha-107105	Sarcophilus harrisii	76.34	0.00e+00	2999.00
IUUC-Ssc-116282	Sus scrofa	79.33	0.00e+00	3124.00
IUUC-Tgu-116807	Taeniopygia guttata	78.86	0.00e+00	3090.00
IUUC-Tru-118040	Takifugu rubripes	76.19	0.00e+00	3005.00
IUUC-Tni-120118	Tetraodon nigroviridis	73.86	0.00e+00	2977.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence