iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125122

Ensembl Protein ID

TRIAE_CS42_2DL_TGACv1_158727_AA0524990.1

UniProt Accession

A0A1D5UKQ7; A0A1D5UKQ7_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_2DL_TGACv1_158727_AA0524990	TRIAE_CS42_2DL_TGACv1_158727_AA0524990.1	TRIAE_CS42_2DL_TGACv1_158727_AA0524990.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-23	82.1	291	323
E3 adaptor/Cullin RING/APC_C/CDC20	6.80e-123	412.5	156	465
UBD/Beta-Prp	1.30e-52	181.5	207	474

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           gH+ +v++l++  s++ l+sG++D+ +++WD++
   Q: 291  GHSQEVCGLKWsgSGRQLASGGNDNLLHIWDVS 323
           8**********976699**************86 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtll 69
           ++ ldap+l dd+ylnLldW+s nvl++aLg++vylw+a++g+ s+l  + e++  vtsvsw ++g+ +
   Q: 156  DRTLDAPDLVDDYYLNLLDWGSANVLSIALGNTVYLWDAASGSTSELVTVdEDDGPVTSVSWAPDGQNI 224
           689***********************************************455557************* PP
   S: 70   avGtkkgeveiyDveekkkvrtl.tghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqaha 137
           a+G ++++v+i+D ++++ +rtl   h +rvg+L+Wn+ +l++G+ dg+i+ +dvr++++ ++t+++h+
   Q: 225  AIGLNSSAVQIWDSSSNRLLRTLqGAHESRVGSLAWNKSILTAGGMDGKIVNNDVRIRDHAVQTYRGHS 293
           ***********************556999**************************************** PP
   S: 138  qevCGlkwnedaklLasGGnDnsvsvwdassse.........PlkkfkehkaavkaiawsPwqkslLas 197
           qevCGlkw+ ++++LasGGnDn +++wd s  +          l+++++h+aavka+aw+P+q++lLas
   Q: 294  QEVCGLKWSGSGRQLASGGNDNLLHIWDVSMASsaqsagrtqWLHRMEDHSAAVKALAWCPFQSNLLAS 362
           ****************************9876666788887788999********************** PP
   S: 198  GGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           GGG++Drcikfwnt tga+l+++dtgsqvc llw k+ +el+s+hGf++n++tlwkyps++k+ael+gh
   Q: 363  GGGANDRCIKFWNTHTGACLNSVDTGSQVCALLWNKNDRELLSSHGFTQNQLTLWKYPSMAKMAELNGH 431
           ********************************************************************* PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdkk 300
           ++Rvl +a spdg ++++aa+Detlrfw++f   
   Q: 432  TSRVLFMAQSPDGCTVASAAADETLRFWNVFPDA 465
           *******************************765 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrt 75
           ++++++t+v ++pd++ +a g  ++ +++wd ++  llr+l   he+ v ++ ++++  il  g+ D+ 
   Q: 207  EDDGPVTSVSWAPDGQNIAIGLNSSAVQIWDSSSNRLLRTLqGAHESRVGSLAWNKS--ILTAGGMDGK 273
           5799*************************************778*************..********** PP
   S: 76   ikvwdls.tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........tlsg 135
           i  +d++     v+t++gh+++v+ l++s sg  l+sG++d+ +++wd++  +  ++          + 
   Q: 274  IVNNDVRiRDHAVQTYRGHSQEVCGLKWSGSGRQLASGGNDNLLHIWDVSMASSAQSagrtqwlhRMED 342
           *999*9967789******************************************9999****9999999 PP
   S: 136  hdgvvncvvvhpdg.nllvsGs..lDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvs..gs 199
           h+++v  +++ p++ nll+sG+  +Dr++++W+  tg +l        ++v  l +++n +el+s  g 
   Q: 343  HSAAVKALAWCPFQsNLLASGGgaNDRCIKFWNTHTGACLNSVD--TGSQVCALLWNKNDRELLSshGF 409
           ********************74339******************5..589999999********994456 PP
   S: 200  ldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           + ++++lw + +   + +lnght+ v+ ++ sp++  ++s+++D+++r+W++  + + ++++ ++
   Q: 410  TQNQLTLWKYPSMAKMAELNGHTSRVLFMAQSPDGCTVASAAADETLRFWNVFPDAPKSAVKEKA 474
           89************************************************998888888777665 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MDAGSDLMSP EKSGRRGARP PLREAGATPS MPPLQEPGSR PRPYMPSLCS TPRNPAVKCY 60
GDRFIPDRSA MDMDMAHYLL TEPRKDRKNG ATPSPGKETY RKLLAEKLLN NRTRILAFRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACGGCTATA TTTTTTTACA CCCTTCCATC TTTGCCTCCC TCCTCCCCCC TGCCGCACCA 60
CTATTTCCAC CCCACGGATC CGCCAAGAAC TCCCCACCCC GCCCCGCACA GAACCAACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000194	Aegilops tauschii	96.78	0.00e+00	964.00
IUUC-Aca-004920	Anolis carolinensis	43.38	4.00e-103	369.00
IUUC-Fal-037558	Ficedula albicollis	47.04	5.00e-108	385.00
IUUC-Hvu-047227	Hordeum vulgare	92.17	0.00e+00	883.00
IUUC-Ont-071660	Oreochromis niloticus	44.73	6.00e-96	345.00
IUUC-Ola-086907	Oryzias latipes	46.34	3.00e-97	349.00
IUUC-Pma-094187	Petromyzon marinus	46.46	2.00e-99	356.00
IUUC-Tgu-117100	Taeniopygia guttata	47.04	5.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence