iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssl-108418

Ensembl Protein ID

EDN93719

UniProt Accession

A7EW77; ATG18_SCLS1

Genbank Protein ID

EDN93719.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

CH476633

Gene Name

atg18; SS1G_09586

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SS1G_09586	EDN93719	EDN93719

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-08	33.3	184	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlrtgvll 36
           H ++ +c+a+ +d tll+++s  gt i+v+++ +g +l
   Q: 184  HRAPLSCIALnNDgTLLATASETGTiIRVFSVPDGQKL 221
           999********999***********999***9999776 PP

Organism

Sclerotinia sclerotiorum

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MNYVTFNQDY TCLAVGTAKG FRIYHTDPFS KIFTGDNENV TIIEMLFSTS LVAIKQSPRH 60
IVIQNTKRGT VICELTFPSA VLAVRLNRKR FAVLLEEEIY LYDIQNMGLL YTISTSANPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATTATG TTACGTTCAA CCAGGACTAC ACCTGCCTGG CAGTTGGTTG GTGTTCTATC 60
TGATCCAATT TCGGGATGTA CTAATGCCTC TTCATCAGGG ACTGCCAAAG GCTTTCGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

KEGG

ssl:SS1G_09586

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	28.81	1.00e-42	164.00
IUUC-Aml-001842	Ailuropoda melanoleuca	35.45	8.00e-64	235.00
IUUC-Atr-002710	Amborella trichopoda	33.74	4.00e-42	162.00
IUUC-Apl-003390	Anas platyrhynchos	35.52	2.00e-64	237.00
IUUC-Aca-004975	Anolis carolinensis	35.80	1.00e-67	248.00
IUUC-Aly-006440	Arabidopsis lyrata	35.21	6.00e-38	149.00
IUUC-Ath-007423	Arabidopsis thaliana	35.05	1.00e-38	151.00
IUUC-Ago-007948	Ashbya gossypii	30.63	4.00e-54	203.00
IUUC-Acl-008148	Aspergillus clavatus	59.71	5.00e-136	475.00
IUUC-Afl-008562	Aspergillus flavus	59.62	3.00e-132	462.00
IUUC-Afu-008936	Aspergillus fumigatus	61.56	4.00e-137	478.00
IUUC-Ani-009254	Aspergillus nidulans	59.06	2.00e-137	479.00
IUUC-Ang-009798	Aspergillus niger	59.95	2.00e-132	463.00
IUUC-Aor-010066	Aspergillus oryzae	59.62	3.00e-132	462.00
IUUC-Ate-010266	Aspergillus terreus	60.10	4.00e-139	485.00
IUUC-Ame-010727	Astyanax mexicanus	36.28	1.00e-68	251.00
IUUC-Bta-012655	Bos taurus	36.10	4.00e-68	249.00
IUUC-Bci-013627	Botrytis cinerea	94.69	0.00e+00	770.00
IUUC-Bdi-014739	Brachypodium distachyon	28.57	3.00e-42	163.00
IUUC-Bol-015492	Brassica oleracea	29.13	2.00e-43	167.00
IUUC-Bra-017242	Brassica rapa	36.36	7.00e-37	145.00
IUUC-Cel-018503	Caenorhabditis elegans	30.56	9.00e-47	178.00
IUUC-Cja-018829	Callithrix jacchus	34.10	2.00e-60	224.00
IUUC-Cfa-020858	Canis familiaris	35.45	2.00e-63	234.00
IUUC-Cpo-022235	Cavia porcellus	35.08	5.00e-65	239.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	34.07	2.00e-39	154.00
IUUC-Csa-023963	Chlorocebus sabaeus	34.72	1.00e-61	228.00
IUUC-Cho-024328	Choloepus hoffmanni	36.39	2.00e-62	230.00
IUUC-Cin-025343	Ciona intestinalis	35.25	8.00e-58	215.00
IUUC-Csv-025920	Ciona savignyi	35.22	9.00e-64	234.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	83.01	9.00e-66	241.00
IUUC-Cne-026947	Cryptococcus neoformans	47.99	2.00e-95	340.00
IUUC-Dre-027490	Danio rerio	36.52	5.00e-69	252.00
IUUC-Dno-030057	Dasypus novemcinctus	35.70	5.00e-65	239.00
IUUC-Dor-030472	Dipodomys ordii	34.69	2.00e-59	221.00
IUUC-Dse-031215	Dothistroma septosporum	45.41	4.00e-107	379.00
IUUC-Dme-031881	Drosophila melanogaster	34.44	5.00e-30	122.00
IUUC-Ete-032276	Echinops telfairi	33.97	1.00e-53	201.00
IUUC-Eca-034362	Equus caballus	35.45	8.00e-65	238.00
IUUC-Eeu-034479	Erinaceus europaeus	33.72	7.00e-22	94.70
IUUC-Fca-036230	Felis catus	35.54	2.00e-64	237.00
IUUC-Fal-036782	Ficedula albicollis	35.70	2.00e-64	237.00
IUUC-Fox-037797	Fusarium oxysporum	68.18	1.00e-147	513.00
IUUC-Fso-038174	Fusarium solani	67.43	4.00e-146	508.00
IUUC-Gmo-039706	Gadus morhua	33.97	7.00e-57	212.00
IUUC-Ggr-040113	Gaeumannomyces graminis	63.11	2.00e-156	542.00
IUUC-Gga-040690	Gallus gallus	35.87	9.00e-68	248.00
IUUC-Gac-041360	Gasterosteus aculeatus	35.56	4.00e-67	246.00
IUUC-Gma-043876	Glycine max	40.29	9.00e-49	184.00
IUUC-Ggo-045610	Gorilla gorilla	30.32	1.00e-31	128.00
IUUC-Hsa-046782	Homo sapiens	34.72	1.00e-61	228.00
IUUC-Hvu-047851	Hordeum vulgare	28.81	1.00e-42	165.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	33.64	7.00e-62	229.00
IUUC-Kpa-049378	Komagataella pastoris	48.40	5.00e-75	273.00
IUUC-Lch-050413	Latimeria chalumnae	36.27	4.00e-63	233.00
IUUC-Lpe-051205	Leersia perrieri	29.59	8.00e-46	175.00
IUUC-Loc-052379	Lepisosteus oculatus	33.08	1.00e-33	134.00
IUUC-Lma-052948	Leptosphaeria maculans	57.35	5.00e-136	475.00
IUUC-Laf-054007	Loxodonta africana	35.80	7.00e-68	248.00
IUUC-Mcc-055304	Macaca mulatta	32.55	3.00e-31	126.00
IUUC-Meu-056020	Macropus eugenii	29.15	5.00e-25	105.00
IUUC-Mor-057125	Magnaporthe oryzae	65.79	6.00e-166	574.00
IUUC-Mpo-057416	Magnaporthe poae	28.78	2.00e-26	111.00
IUUC-Mtr-058536	Medicago truncatula	30.79	9.00e-46	175.00
IUUC-Mla-058885	Melampsora laricipopulina	35.00	2.00e-14	70.10
IUUC-Mga-059795	Meleagris gallopavo	35.52	2.00e-64	237.00
IUUC-Mvi-060219	Microbotryum violaceum	48.71	6.00e-99	352.00
IUUC-Mmr-061096	Microcebus murinus	35.75	7.00e-65	239.00
IUUC-Mdo-062881	Monodelphis domestica	35.48	4.00e-67	246.00
IUUC-Mmu-063787	Mus musculus	35.63	5.00e-68	249.00
IUUC-Mac-064838	Musa acuminata	35.84	2.00e-45	174.00
IUUC-Mpu-066019	Mustela putorius furo	32.95	1.00e-57	214.00
IUUC-Mlu-068016	Myotis lucifugus	36.34	1.00e-68	251.00
IUUC-Nfi-068424	Neosartorya fischeri	62.35	3.00e-138	482.00
IUUC-Ncr-068833	Neurospora crassa	65.64	8.00e-152	527.00
IUUC-Nle-069047	Nomascus leucogenys	33.46	7.00e-37	145.00
IUUC-Opr-070933	Ochotona princeps	33.13	3.00e-43	167.00
IUUC-Ont-072495	Oreochromis niloticus	36.04	9.00e-68	248.00
IUUC-Oan-073084	Ornithorhynchus anatinus	36.36	2.00e-62	231.00
IUUC-Ocu-074689	Oryctolagus cuniculus	34.61	9.00e-64	235.00
IUUC-Oba-075827	Oryza barthii	30.31	1.00e-45	175.00
IUUC-Obr-076476	Oryza brachyantha	29.83	5.00e-45	172.00
IUUC-Ogl-077630	Oryza glaberrima	30.31	1.00e-45	175.00
IUUC-Ogu-078126	Oryza glumaepatula	30.07	3.00e-45	173.00
IUUC-Oin-080115	Oryza indica	30.31	1.00e-45	175.00
IUUC-Olo-080657	Oryza longistaminata	31.28	3.00e-44	171.00
IUUC-Ome-081702	Oryza meridionalis	35.06	2.00e-42	164.00
IUUC-Oni-082884	Oryza nivara	30.31	2.00e-44	172.00
IUUC-Opu-083460	Oryza punctata	30.31	2.00e-44	171.00
IUUC-Oru-084193	Oryza rufipogon	30.31	1.00e-45	175.00
IUUC-Osa-085948	Oryza sativa	30.31	1.00e-45	175.00
IUUC-Ola-086628	Oryzias latipes	34.93	5.00e-39	152.00
IUUC-Olu-087808	Ostreococcus lucimarinus	28.17	1.00e-40	158.00
IUUC-Oga-088894	Otolemur garnettii	33.87	4.00e-62	229.00
IUUC-Oar-089850	Ovis aries	35.52	1.00e-64	238.00
IUUC-Ptr-090456	Pan troglodytes	34.72	1.00e-61	228.00
IUUC-Pan-092111	Papio anubis	35.32	2.00e-65	240.00
IUUC-Psi-094095	Pelodiscus sinensis	35.77	6.00e-65	238.00
IUUC-Pma-094403	Petromyzon marinus	30.50	2.00e-30	124.00
IUUC-Pno-095015	Phaeosphaeria nodorum	56.77	2.00e-129	452.00
IUUC-Ppa-095480	Physcomitrella patens	33.49	1.00e-45	174.00
IUUC-Pfo-096987	Poecilia formosa	36.28	3.00e-68	249.00
IUUC-Pab-097754	Pongo abelii	34.72	1.00e-61	228.00
IUUC-Pop-099157	Populus trichocarpa	30.05	1.00e-42	164.00
IUUC-Pca-100176	Procavia capensis	27.34	3.00e-23	100.00
IUUC-Ppe-101963	Prunus persica	36.70	3.00e-36	143.00
IUUC-Pva-103047	Pteropus vampyrus	34.32	2.00e-64	237.00
IUUC-Pgr-103258	Puccinia graminis	24.41	3.00e-15	74.70
IUUC-Ptt-103915	Puccinia triticina	24.91	8.00e-19	86.30
IUUC-Pte-104139	Pyrenophora teres	55.98	2.00e-127	446.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	55.34	3.00e-127	446.00
IUUC-Rno-105990	Rattus norvegicus	35.87	3.00e-68	249.00
IUUC-Sce-106327	Saccharomyces cerevisiae	33.60	7.00e-77	278.00
IUUC-Sha-106581	Sarcophilus harrisii	35.45	1.00e-64	238.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	41.45	4.00e-80	289.00
IUUC-Spo-108068	Schizosaccharomyces pombe	49.40	3.00e-64	236.00
IUUC-Smo-108755	Selaginella moellendorffii	32.78	1.00e-52	198.00
IUUC-Sit-110095	Setaria italica	29.83	1.00e-43	168.00
IUUC-Sly-111030	Solanum lycopersicum	29.18	2.00e-42	164.00
IUUC-Stu-111954	Solanum tuberosum	29.11	3.00e-38	150.00
IUUC-Sar-113276	Sorex araneus	33.72	8.00e-22	94.70
IUUC-Sbi-114020	Sorghum bicolor	29.36	9.00e-43	165.00
IUUC-Sre-115219	Sporisorium reilianum	46.78	8.00e-102	361.00
IUUC-Ssc-116360	Sus scrofa	36.34	1.00e-68	251.00
IUUC-Tgu-116951	Taeniopygia guttata	35.52	2.00e-64	237.00
IUUC-Tru-117889	Takifugu rubripes	34.56	5.00e-64	236.00
IUUC-Tsy-119533	Tarsius syrichta	43.04	1.00e-18	84.00
IUUC-Tni-119984	Tetraodon nigroviridis	29.54	3.00e-31	127.00
IUUC-Tca-121732	Theobroma cacao	31.33	4.00e-36	143.00
IUUC-Tre-121895	Trichoderma reesei	69.34	8.00e-167	577.00
IUUC-Tvi-122311	Trichoderma virens	66.00	9.00e-168	580.00
IUUC-Tae-123911	Triticum aestivum	28.81	3.00e-43	166.00
IUUC-Tur-126757	Triticum urartu	28.81	4.00e-43	166.00
IUUC-Ttr-128940	Tursiops truncatus	32.61	4.00e-28	115.00
IUUC-Uma-129438	Ustilago maydis	49.30	1.00e-93	334.00
IUUC-Vda-129782	Verticillium dahliae	62.94	4.00e-118	415.00
IUUC-Vvi-131674	Vitis vinifera	31.28	4.00e-46	176.00
IUUC-Xtr-131806	Xenopus tropicalis	34.56	2.00e-37	147.00
IUUC-Xma-133370	Xiphophorus maculatus	36.28	3.00e-68	249.00
IUUC-Yli-134337	Yarrowia lipolytica	49.53	8.00e-103	364.00
IUUC-Zma-135902	Zea mays	30.00	1.00e-37	148.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence