iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026107

UUCD1 version

UUC-CiS-00018

Ensembl Protein ID

ENSCSAVP00000017640.1

UniProt Accession

H2ZJ74; H2ZJ74_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000010386.1	ENSCSAVT00000017831.1	ENSCSAVP00000017639.1
ENSCSAVG00000010386.1	ENSCSAVT00000017832.1	ENSCSAVP00000017640.1
ENSCSAVG00000010386.1	ENSCSAVT00000017833.1	ENSCSAVP00000017641.1
ENSCSAVG00000010386.1	ENSCSAVT00000017834.1	ENSCSAVP00000017642.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	3.30e-201	670.2	19	639

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlrkifay 89
           l++a+++i+++++   ++eely+++y+++l+k+g+klY+ l+ev++e++ +v+ ++ +s ++++L+++n +W ++++ ++++r+i++y
   Q: 19   LKKAIQEIQKKNNGGLSFEELYRNAYTMVLHKHGEKLYTGLHEVVTEHLMKVRGDILHSLNNNFLQVLNSAWDDHQTCMVMIRDILMY 106
           799************************************************************************************* PP
   S: 90   ldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakflea 175
           +dr+yv++ ++v +v++L+l+++r++++++  i++ ++ +ll+l+++eR ge+vdr  +++ + +l+ Lsln + +y++ FE+ fle+
   Q: 107  MDRVYVSQ-NNVDSVYNLGLKIFRDQVIRQkdIREFIQYTLLELVAKERRGEVVDRGAVRNTCMMLMTLSLNGRDVYEQEFEKGFLEQ 193
           ********.*******************9888******************************************************** PP
   S: 176  tqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll....aelvallrdkktedlsrmy 259
           +++fy++es++fl en+ ++Ylkkvear++ee era++yl++ste ++++v+e+eli+ h++ ++    ++ v +l+++ ++dl rmy
   Q: 194  SSNFYQMESHKFLVENSASQYLKKVEARIEEEAERARHYLDPSTEPEIIAVLERELIQRHMKIVVemenSGAVYMLQHDIKDDLLRMY 281
           ****************************************************************9999999***************** PP
   S: 260  kLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaak 347
           +L+ rv++g e+l+++l+++++eqgka++++  + k+p++y++ ll+lk++++++ +++F+nd+ F k + ++fe fvn n     +k
   Q: 282  QLFVRVPQGFETLRDCLSAYLREQGKAVVEDGGQ-KTPVDYIQALLDLKDRMDDFHKHSFKNDPLFKKMICSDFEWFVNLN-----PK 363
           **************************99997665.5569******************************************.....** PP
   S: 348  spEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLe 435
           spE+l+ +iD++L+k++k+l e+e+e  ldk + +f++++ekdvFe+yYk+hL +RLl++ks s+++E+++i+kLk+ecg++ftskLe
   Q: 364  SPEYLSLFIDDKLKKGIKMLSEQEVEVVLDKTMALFRFLQEKDVFERYYKQHLGRRLLTNKSISDDSEKNMITKLKNECGCQFTSKLE 451
           **************************************************************************************** PP
   S: 436  rMfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelk 523
           +Mf+d++vS ++n++Fk   ++ + s+ ++l+v+vL++g+Wpt+++t++++LPa  +++++ f++fYl khsgR+L++qh+ g a+++
   Q: 452  GMFKDMHVSATTNEDFK---KHVQSSAVFDLTVQVLTTGCWPTQASTPTCNLPAAPRHAFDVFRRFYLGKHSGRQLTLQHHRGAADMN 536
           *****************...66667899************************************************************ PP
   S: 524  ael....................kkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkepes 589
           a +                    ++++++lqVstfQm+vL++fn++ek+ +ee++++te+p++eL r+lqsL+++k  ++vl+kep++
   Q: 537  ASFystpkqsvategeatssskpSARRHILQVSTFQMVVLMLFNDREKWLFEEIQQETEIPAKELSRALQSLACGKanQRVLHKEPKG 624
           ***99999999999888887777777**************************************************99********** PP
   S: 590  keieeedlfsvNqef 604
           keie++++f+vN++f
   Q: 625  KEIEKGNVFIVNDNF 639
           *************99 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

FGFQMTIDEK YVANIWDLLK KAIQEIQKKN NGGLSFEELY RNAYTMVLHK HGEKLYTGLH 60
EVVTEHLMKV RGDILHSLNN NFLQVLNSAW DDHQTCMVMI RDILMYMDRV YVSQNNVDSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTGCGTAT GTAATATAAA AGTTAGCAGA TATTTAGACT GTTTTTTTGT GTGTTTGTTT 60
TGCAAAATGT CGCGCCTTTC ACAACCAACA AAGAAAGACA CAAAAATGAG AATACGAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000335	Aegilops tauschii	44.07	5.00e-179	619.00
IUUC-Aml-002278	Ailuropoda melanoleuca	71.01	0.00e+00	1065.00
IUUC-Atr-002616	Amborella trichopoda	51.01	0.00e+00	723.00
IUUC-Apl-004172	Anas platyrhynchos	71.39	0.00e+00	1066.00
IUUC-Aca-004309	Anolis carolinensis	71.24	0.00e+00	1068.00
IUUC-Aly-005566	Arabidopsis lyrata	50.40	0.00e+00	711.00
IUUC-Ath-007587	Arabidopsis thaliana	50.40	0.00e+00	710.00
IUUC-Ago-007795	Ashbya gossypii	24.83	8.00e-40	157.00
IUUC-Acl-008317	Aspergillus clavatus	36.26	2.00e-131	461.00
IUUC-Afl-008727	Aspergillus flavus	35.80	8.00e-133	466.00
IUUC-Afu-008879	Aspergillus fumigatus	37.38	2.00e-122	431.00
IUUC-Ani-009393	Aspergillus nidulans	34.97	4.00e-122	430.00
IUUC-Ang-009626	Aspergillus niger	36.04	3.00e-127	447.00
IUUC-Aor-010207	Aspergillus oryzae	35.80	2.00e-132	464.00
IUUC-Ate-010305	Aspergillus terreus	36.70	2.00e-131	461.00
IUUC-Ame-011805	Astyanax mexicanus	71.64	0.00e+00	1064.00
IUUC-Bgr-012098	Blumeria graminis	32.93	7.00e-106	376.00
IUUC-Bta-013445	Bos taurus	71.24	0.00e+00	1068.00
IUUC-Bci-013612	Botrytis cinerea	36.42	3.00e-128	451.00
IUUC-Bdi-014269	Brachypodium distachyon	50.07	0.00e+00	678.00
IUUC-Bol-015350	Brassica oleracea	51.08	0.00e+00	716.00
IUUC-Bra-016763	Brassica rapa	51.08	0.00e+00	717.00
IUUC-Cel-018641	Caenorhabditis elegans	46.73	0.00e+00	668.00
IUUC-Cja-019175	Callithrix jacchus	71.24	0.00e+00	1067.00
IUUC-Cfa-020905	Canis familiaris	71.33	0.00e+00	1068.00
IUUC-Cpo-021293	Cavia porcellus	71.33	0.00e+00	1067.00
IUUC-Cre-022776	Chlamydomonas reinhardtii	47.34	0.00e+00	638.00
IUUC-Csa-023800	Chlorocebus sabaeus	71.24	0.00e+00	1066.00
IUUC-Cho-024839	Choloepus hoffmanni	68.91	0.00e+00	921.00
IUUC-Cin-025201	Ciona intestinalis	91.44	0.00e+00	1268.00
IUUC-Cgl-026630	Colletotrichum gloeosporioides	34.62	1.00e-111	395.00
IUUC-Cne-027048	Cryptococcus neoformans	35.72	1.00e-115	409.00
IUUC-Cme-027254	Cyanidioschyzon merolae	30.85	2.00e-89	322.00
IUUC-Dre-028793	Danio rerio	71.64	0.00e+00	1063.00
IUUC-Dno-029784	Dasypus novemcinctus	71.24	0.00e+00	1068.00
IUUC-Dor-030682	Dipodomys ordii	65.37	0.00e+00	932.00
IUUC-Dse-031326	Dothistroma septosporum	35.95	8.00e-118	416.00
IUUC-Dme-032112	Drosophila melanogaster	61.82	0.00e+00	919.00
IUUC-Ete-032347	Echinops telfairi	59.17	0.00e+00	818.00
IUUC-Eca-033560	Equus caballus	71.52	0.00e+00	1066.00
IUUC-Eeu-034502	Erinaceus europaeus	68.33	0.00e+00	918.00
IUUC-Fca-035544	Felis catus	71.39	0.00e+00	1066.00
IUUC-Fal-036751	Ficedula albicollis	71.39	0.00e+00	1066.00
IUUC-Fox-037857	Fusarium oxysporum	34.77	1.00e-120	426.00
IUUC-Fso-038163	Fusarium solani	35.26	3.00e-122	431.00
IUUC-Gmo-038830	Gadus morhua	70.84	0.00e+00	1057.00
IUUC-Ggr-039999	Gaeumannomyces graminis	40.48	4.00e-83	301.00
IUUC-Gga-040329	Gallus gallus	71.37	0.00e+00	1069.00
IUUC-Gac-041510	Gasterosteus aculeatus	70.94	0.00e+00	1065.00
IUUC-Gma-043659	Glycine max	51.92	0.00e+00	707.00
IUUC-Ggo-044903	Gorilla gorilla	71.30	0.00e+00	1058.00
IUUC-Hsa-046000	Homo sapiens	71.24	0.00e+00	1066.00
IUUC-Hvu-047831	Hordeum vulgare	50.07	0.00e+00	638.00
IUUC-Itr-049067	Ictidomys tridecemlineatus	71.81	0.00e+00	682.00
IUUC-Kpa-049372	Komagataella pastoris	32.77	8.00e-106	376.00
IUUC-Lch-050458	Latimeria chalumnae	71.47	0.00e+00	1067.00
IUUC-Lpe-051396	Leersia perrieri	50.47	0.00e+00	700.00
IUUC-Loc-052186	Lepisosteus oculatus	71.64	0.00e+00	1071.00
IUUC-Lma-053030	Leptosphaeria maculans	36.62	5.00e-128	450.00
IUUC-Laf-053684	Loxodonta africana	71.39	0.00e+00	1066.00
IUUC-Mcc-055770	Macaca mulatta	71.24	0.00e+00	1066.00
IUUC-Meu-056852	Macropus eugenii	72.55	5.00e-162	563.00
IUUC-Mor-057273	Magnaporthe oryzae	34.35	8.00e-119	419.00
IUUC-Mpo-057403	Magnaporthe poae	33.85	2.00e-114	405.00
IUUC-Mtr-058317	Medicago truncatula	50.40	0.00e+00	702.00
IUUC-Mla-059055	Melampsora laricipopulina	37.64	2.00e-130	458.00
IUUC-Mga-060076	Meleagris gallopavo	70.72	0.00e+00	1051.00
IUUC-Mvi-060470	Microbotryum violaceum	34.22	5.00e-131	460.00
IUUC-Mmr-060976	Microcebus murinus	71.24	0.00e+00	1068.00
IUUC-Mdo-062741	Monodelphis domestica	71.24	0.00e+00	1068.00
IUUC-Mmu-063905	Mus musculus	71.24	0.00e+00	1068.00
IUUC-Mac-064718	Musa acuminata	49.20	0.00e+00	679.00
IUUC-Mpu-066356	Mustela putorius furo	71.39	0.00e+00	1066.00
IUUC-Mlu-067768	Myotis lucifugus	71.01	0.00e+00	1064.00
IUUC-Nfi-068285	Neosartorya fischeri	36.72	9.00e-134	469.00
IUUC-Ncr-068883	Neurospora crassa	35.52	2.00e-120	425.00
IUUC-Nle-069638	Nomascus leucogenys	71.33	0.00e+00	1063.00
IUUC-Opr-070333	Ochotona princeps	70.75	0.00e+00	765.00
IUUC-Ont-071601	Oreochromis niloticus	71.50	0.00e+00	1096.00
IUUC-Oan-073281	Ornithorhynchus anatinus	69.16	0.00e+00	884.00
IUUC-Ocu-074504	Oryctolagus cuniculus	71.28	0.00e+00	1069.00
IUUC-Oba-075332	Oryza barthii	50.47	0.00e+00	694.00
IUUC-Obr-076790	Oryza brachyantha	48.25	0.00e+00	666.00
IUUC-Ogl-077655	Oryza glaberrima	50.47	0.00e+00	702.00
IUUC-Ogu-078458	Oryza glumaepatula	50.47	0.00e+00	693.00
IUUC-Oin-079567	Oryza indica	50.34	0.00e+00	700.00
IUUC-Olo-080930	Oryza longistaminata	50.74	0.00e+00	702.00
IUUC-Ome-081353	Oryza meridionalis	50.47	0.00e+00	701.00
IUUC-Oni-082378	Oryza nivara	50.47	0.00e+00	702.00
IUUC-Opu-084055	Oryza punctata	50.47	0.00e+00	702.00
IUUC-Oru-084202	Oryza rufipogon	50.47	0.00e+00	694.00
IUUC-Osa-085290	Oryza sativa	50.47	0.00e+00	702.00
IUUC-Ola-087562	Oryzias latipes	71.64	0.00e+00	1070.00
IUUC-Olu-087866	Ostreococcus lucimarinus	37.10	4.00e-132	463.00
IUUC-Oga-088833	Otolemur garnettii	71.39	0.00e+00	1066.00
IUUC-Oar-089958	Ovis aries	71.39	0.00e+00	1066.00
IUUC-Ptr-091013	Pan troglodytes	71.24	0.00e+00	1066.00
IUUC-Pan-091796	Papio anubis	70.92	0.00e+00	1058.00
IUUC-Psi-093564	Pelodiscus sinensis	70.32	0.00e+00	1036.00
IUUC-Pno-094939	Phaeosphaeria nodorum	37.35	6.00e-125	440.00
IUUC-Ppa-095920	Physcomitrella patens	49.46	0.00e+00	706.00
IUUC-Pfo-096588	Poecilia formosa	70.57	0.00e+00	1051.00
IUUC-Pab-098164	Pongo abelii	71.24	0.00e+00	1066.00
IUUC-Pop-099497	Populus trichocarpa	51.34	0.00e+00	728.00
IUUC-Pca-100702	Procavia capensis	70.02	7.00e-176	609.00
IUUC-Ppe-101971	Prunus persica	50.87	0.00e+00	693.00
IUUC-Pva-103129	Pteropus vampyrus	71.37	0.00e+00	1068.00
IUUC-Pgr-103684	Puccinia graminis	36.36	4.00e-106	377.00
IUUC-Ptt-103961	Puccinia triticina	36.41	9.00e-107	379.00
IUUC-Pte-104325	Pyrenophora teres	37.08	9.00e-126	442.00
IUUC-Pyt-104746	Pyrenophora triticirepentis	36.18	2.00e-123	434.00
IUUC-Rno-105935	Rattus norvegicus	71.39	0.00e+00	1067.00
IUUC-Sha-106569	Sarcophilus harrisii	69.78	0.00e+00	952.00
IUUC-Sja-107676	Schizosaccharomyces japonicus	38.97	2.00e-148	517.00
IUUC-Spo-108135	Schizosaccharomyces pombe	38.22	1.00e-132	465.00
IUUC-Smo-109555	Selaginella moellendorffii	51.55	0.00e+00	733.00
IUUC-Sit-110763	Setaria italica	50.60	0.00e+00	697.00
IUUC-Sly-111090	Solanum lycopersicum	49.93	0.00e+00	717.00
IUUC-Stu-112351	Solanum tuberosum	50.20	0.00e+00	721.00
IUUC-Sar-113144	Sorex araneus	70.93	0.00e+00	775.00
IUUC-Sbi-114690	Sorghum bicolor	50.47	0.00e+00	704.00
IUUC-Sre-115005	Sporisorium reilianum	38.62	1.00e-129	455.00
IUUC-Ssc-116053	Sus scrofa	69.93	0.00e+00	783.00
IUUC-Tgu-116523	Taeniopygia guttata	71.39	0.00e+00	1066.00
IUUC-Tru-118189	Takifugu rubripes	68.71	0.00e+00	995.00
IUUC-Tsy-118962	Tarsius syrichta	66.98	0.00e+00	963.00
IUUC-Tni-120614	Tetraodon nigroviridis	49.06	0.00e+00	711.00
IUUC-Tca-121282	Theobroma cacao	51.48	0.00e+00	724.00
IUUC-Tre-122201	Trichoderma reesei	35.96	5.00e-122	430.00
IUUC-Tvi-122321	Trichoderma virens	35.83	1.00e-118	419.00
IUUC-Tae-124292	Triticum aestivum	50.07	0.00e+00	674.00
IUUC-Tur-126800	Triticum urartu	50.07	0.00e+00	673.00
IUUC-Tme-127053	Tuber melanosporum	38.78	3.00e-144	504.00
IUUC-Tbe-127427	Tupaia belangeri	59.29	0.00e+00	769.00
IUUC-Ttr-128662	Tursiops truncatus	70.19	0.00e+00	1036.00
IUUC-Uma-129597	Ustilago maydis	37.83	7.00e-129	453.00
IUUC-Vda-129726	Verticillium dahliae	33.25	8.00e-114	402.00
IUUC-Vpa-130809	Vicugna pacos	70.16	2.00e-141	494.00
IUUC-Vvi-131194	Vitis vinifera	50.27	0.00e+00	711.00
IUUC-Xtr-131887	Xenopus tropicalis	71.05	0.00e+00	1061.00
IUUC-Xma-133517	Xiphophorus maculatus	71.50	0.00e+00	1068.00
IUUC-Yli-134576	Yarrowia lipolytica	33.89	1.00e-102	365.00
IUUC-Zma-135030	Zea mays	50.60	0.00e+00	710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence