iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019282

UUCD1 version

UUC-CaJ-00623

Ensembl Protein ID

ENSCJAP00000020758.2

UniProt Accession

F7GVV3; F7GVV3_CALJA

Genbank Protein ID

JAB36373.1; JAB43997.1

Protein Name

Aurora kinase A

Genbank Nucleotide ID

ACFV01140926; GAMP01008758

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000011266.2	ENSCJAT00000021941.2	ENSCJAP00000020758.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	96.03	0.00e+00	771.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MDRSKENCIS GPVKAVAPVG VPKRVLVTQQ FPCQNPLPAN SGQAQRVLCP SNSSQRVPLQ 60
AQKLVSNHKP VQKQKQLQAT SVPHPVCRPL SNTQKSKQPQ SSAPENNPEE ELASKQKNEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAAGGCAGC CTCTCTCCAG TGCAGGCCAA TCGGCTTTCT GGTTAGAGGG TTTAACTCCT 60
ATTTAAAAAG AAGAACCTTT GAATTCTAAC GGCTAAGCTC TTGGAAGAAT CGCGTCCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

KEGG

cjc:100398107

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.44	6.00e-103	366.00
IUUC-Aml-001426	Ailuropoda melanoleuca	90.96	0.00e+00	723.00
IUUC-Atr-002453	Amborella trichopoda	63.89	1.00e-107	382.00
IUUC-Apl-003626	Anas platyrhynchos	70.68	1.00e-153	535.00
IUUC-Aca-004602	Anolis carolinensis	65.75	2.00e-146	512.00
IUUC-Aly-005878	Arabidopsis lyrata	64.31	1.00e-104	372.00
IUUC-Ath-007117	Arabidopsis thaliana	65.06	3.00e-105	374.00
IUUC-Acl-008199	Aspergillus clavatus	55.05	7.00e-87	313.00
IUUC-Afl-008419	Aspergillus flavus	55.84	3.00e-86	311.00
IUUC-Afu-008751	Aspergillus fumigatus	50.00	7.00e-87	313.00
IUUC-Ani-009181	Aspergillus nidulans	50.32	7.00e-90	323.00
IUUC-Ang-009787	Aspergillus niger	51.76	3.00e-88	318.00
IUUC-Aor-009980	Aspergillus oryzae	55.84	3.00e-86	311.00
IUUC-Ate-010286	Aspergillus terreus	49.70	2.00e-86	312.00
IUUC-Ame-010849	Astyanax mexicanus	70.85	9.00e-128	449.00
IUUC-Bgr-012110	Blumeria graminis	58.80	7.00e-89	320.00
IUUC-Bta-013474	Bos taurus	88.59	0.00e+00	719.00
IUUC-Bci-013756	Botrytis cinerea	57.86	2.00e-94	338.00
IUUC-Bdi-014257	Brachypodium distachyon	63.25	2.00e-104	371.00
IUUC-Bol-016310	Brassica oleracea	61.54	2.00e-102	365.00
IUUC-Bra-017438	Brassica rapa	61.54	6.00e-104	370.00
IUUC-Cel-018157	Caenorhabditis elegans	57.09	5.00e-101	360.00
IUUC-Cfa-020162	Canis familiaris	89.41	0.00e+00	716.00
IUUC-Cpo-021764	Cavia porcellus	83.70	0.00e+00	665.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	67.29	5.00e-108	383.00
IUUC-Csa-023694	Chlorocebus sabaeus	95.04	0.00e+00	714.00
IUUC-Cho-024350	Choloepus hoffmanni	95.92	9.00e-113	399.00
IUUC-Cin-025542	Ciona intestinalis	72.73	3.00e-117	414.00
IUUC-Csv-025873	Ciona savignyi	65.20	1.00e-117	415.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	54.35	1.00e-81	296.00
IUUC-Cne-026928	Cryptococcus neoformans	59.48	1.00e-94	340.00
IUUC-Cme-027336	Cyanidioschyzon merolae	61.01	2.00e-119	422.00
IUUC-Dre-028198	Danio rerio	62.30	3.00e-130	458.00
IUUC-Dno-029928	Dasypus novemcinctus	85.01	0.00e+00	638.00
IUUC-Dor-030238	Dipodomys ordii	78.91	0.00e+00	633.00
IUUC-Dse-031266	Dothistroma septosporum	49.72	3.00e-93	335.00
IUUC-Dme-032007	Drosophila melanogaster	61.45	4.00e-100	358.00
IUUC-Ete-032911	Echinops telfairi	66.23	1.00e-130	459.00
IUUC-Eca-033749	Equus caballus	90.96	0.00e+00	713.00
IUUC-Eeu-035170	Erinaceus europaeus	86.42	0.00e+00	707.00
IUUC-Fca-035498	Felis catus	89.95	0.00e+00	707.00
IUUC-Fal-037397	Ficedula albicollis	64.22	7.00e-147	513.00
IUUC-Fox-037747	Fusarium oxysporum	54.17	1.00e-91	330.00
IUUC-Fso-038429	Fusarium solani	52.87	8.00e-91	327.00
IUUC-Gmo-039378	Gadus morhua	74.36	2.00e-124	439.00
IUUC-Ggr-039939	Gaeumannomyces graminis	57.59	6.00e-96	344.00
IUUC-Gga-040187	Gallus gallus	70.00	4.00e-151	527.00
IUUC-Gac-042223	Gasterosteus aculeatus	70.13	4.00e-129	454.00
IUUC-Gma-042870	Glycine max	62.59	6.00e-99	353.00
IUUC-Ggo-045617	Gorilla gorilla	95.78	0.00e+00	796.00
IUUC-Hsa-046968	Homo sapiens	96.03	0.00e+00	798.00
IUUC-Hvu-047072	Hordeum vulgare	54.85	1.00e-80	292.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	77.81	2.00e-176	611.00
IUUC-Kpa-049093	Komagataella pastoris	55.56	5.00e-76	277.00
IUUC-Lch-050346	Latimeria chalumnae	66.34	9.00e-146	509.00
IUUC-Lpe-051466	Leersia perrieri	63.73	8.00e-105	373.00
IUUC-Lma-053006	Leptosphaeria maculans	56.07	4.00e-89	321.00
IUUC-Laf-053422	Loxodonta africana	84.90	0.00e+00	694.00
IUUC-Mcc-055245	Macaca mulatta	94.95	0.00e+00	706.00
IUUC-Mor-056952	Magnaporthe oryzae	56.88	2.00e-91	328.00
IUUC-Mpo-057605	Magnaporthe poae	56.85	8.00e-97	347.00
IUUC-Mtr-057726	Medicago truncatula	63.64	3.00e-104	371.00
IUUC-Mla-059174	Melampsora laricipopulina	62.93	4.00e-98	351.00
IUUC-Mga-059562	Meleagris gallopavo	61.35	3.00e-117	415.00
IUUC-Mvi-060305	Microbotryum violaceum	61.60	1.00e-93	336.00
IUUC-Mmr-061588	Microcebus murinus	89.05	0.00e+00	738.00
IUUC-Mdo-061914	Monodelphis domestica	77.32	5.00e-174	603.00
IUUC-Mmu-063288	Mus musculus	82.34	0.00e+00	654.00
IUUC-Mac-064969	Musa acuminata	63.99	7.00e-106	376.00
IUUC-Mpu-066855	Mustela putorius furo	89.41	0.00e+00	709.00
IUUC-Mlu-068046	Myotis lucifugus	88.89	0.00e+00	700.00
IUUC-Nfi-068527	Neosartorya fischeri	52.09	6.00e-87	314.00
IUUC-Ncr-068678	Neurospora crassa	57.80	8.00e-94	337.00
IUUC-Nle-069848	Nomascus leucogenys	95.53	0.00e+00	793.00
IUUC-Opr-070589	Ochotona princeps	81.14	0.00e+00	632.00
IUUC-Ont-071733	Oreochromis niloticus	61.15	1.00e-123	436.00
IUUC-Oan-073399	Ornithorhynchus anatinus	87.12	6.00e-154	536.00
IUUC-Ocu-074063	Oryctolagus cuniculus	87.06	0.00e+00	716.00
IUUC-Oba-075264	Oryza barthii	63.99	7.00e-105	373.00
IUUC-Obr-076048	Oryza brachyantha	63.29	5.00e-104	370.00
IUUC-Ogl-077637	Oryza glaberrima	66.04	2.00e-103	368.00
IUUC-Ogu-078830	Oryza glumaepatula	63.99	4.00e-105	374.00
IUUC-Oin-079150	Oryza indica	63.99	3.00e-105	374.00
IUUC-Olo-080398	Oryza longistaminata	57.68	2.00e-82	298.00
IUUC-Ome-081544	Oryza meridionalis	55.15	9.00e-90	323.00
IUUC-Oni-082250	Oryza nivara	63.99	3.00e-105	374.00
IUUC-Opu-083638	Oryza punctata	64.34	9.00e-106	376.00
IUUC-Oru-084981	Oryza rufipogon	63.99	2.00e-105	375.00
IUUC-Osa-085961	Oryza sativa	63.99	2.00e-105	375.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.58	8.00e-112	396.00
IUUC-Oga-088891	Otolemur garnettii	89.09	0.00e+00	709.00
IUUC-Oar-090021	Ovis aries	88.34	0.00e+00	696.00
IUUC-Ptr-091458	Pan troglodytes	96.28	0.00e+00	799.00
IUUC-Pan-092546	Papio anubis	94.79	0.00e+00	716.00
IUUC-Psi-093280	Pelodiscus sinensis	74.06	2.00e-160	558.00
IUUC-Pma-094298	Petromyzon marinus	76.60	2.00e-120	425.00
IUUC-Pno-094847	Phaeosphaeria nodorum	56.74	7.00e-89	320.00
IUUC-Ppa-095855	Physcomitrella patens	65.93	9.00e-108	382.00
IUUC-Pfo-096428	Poecilia formosa	61.19	2.00e-127	448.00
IUUC-Pab-098696	Pongo abelii	95.30	0.00e+00	782.00
IUUC-Pop-099405	Populus trichocarpa	61.89	9.00e-106	376.00
IUUC-Pca-100740	Procavia capensis	80.20	0.00e+00	657.00
IUUC-Ppe-101854	Prunus persica	63.51	2.00e-106	378.00
IUUC-Pva-103212	Pteropus vampyrus	88.37	0.00e+00	694.00
IUUC-Pgr-103474	Puccinia graminis	62.88	4.00e-98	351.00
IUUC-Ptt-103933	Puccinia triticina	48.65	3.00e-61	228.00
IUUC-Pte-104089	Pyrenophora teres	56.18	2.00e-89	322.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	56.18	3.00e-89	322.00
IUUC-Rno-105057	Rattus norvegicus	84.08	0.00e+00	669.00
IUUC-Sha-107137	Sarcophilus harrisii	78.81	2.00e-176	612.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	59.56	4.00e-98	350.00
IUUC-Spo-108078	Schizosaccharomyces pombe	60.73	7.00e-101	360.00
IUUC-Smo-109288	Selaginella moellendorffii	63.99	1.00e-107	382.00
IUUC-Sit-110246	Setaria italica	63.64	2.00e-105	374.00
IUUC-Sly-111379	Solanum lycopersicum	64.36	9.00e-106	376.00
IUUC-Stu-112777	Solanum tuberosum	61.54	5.00e-106	377.00
IUUC-Sbi-114325	Sorghum bicolor	64.16	1.00e-104	372.00
IUUC-Sre-115203	Sporisorium reilianum	58.65	1.00e-80	293.00
IUUC-Ssc-115361	Sus scrofa	88.06	0.00e+00	716.00
IUUC-Tgu-116967	Taeniopygia guttata	71.43	5.00e-147	513.00
IUUC-Tru-117570	Takifugu rubripes	61.08	1.00e-135	476.00
IUUC-Tsy-119280	Tarsius syrichta	70.32	1.00e-149	522.00
IUUC-Tni-120721	Tetraodon nigroviridis	60.14	3.00e-134	471.00
IUUC-Tca-121494	Theobroma cacao	61.97	3.00e-105	374.00
IUUC-Tre-121869	Trichoderma reesei	54.46	2.00e-94	338.00
IUUC-Tvi-122510	Trichoderma virens	55.56	7.00e-94	337.00
IUUC-Tae-123071	Triticum aestivum	63.44	6.00e-103	366.00
IUUC-Tur-126240	Triticum urartu	63.44	2.00e-102	365.00
IUUC-Tme-126921	Tuber melanosporum	60.36	8.00e-96	343.00
IUUC-Tbe-127872	Tupaia belangeri	83.42	0.00e+00	640.00
IUUC-Ttr-129134	Tursiops truncatus	88.89	0.00e+00	677.00
IUUC-Uma-129412	Ustilago maydis	59.25	9.00e-80	290.00
IUUC-Vda-130003	Verticillium dahliae	56.34	4.00e-92	331.00
IUUC-Vvi-131272	Vitis vinifera	63.29	6.00e-106	376.00
IUUC-Xtr-132019	Xenopus tropicalis	64.53	2.00e-147	515.00
IUUC-Xma-134203	Xiphophorus maculatus	60.45	5.00e-133	467.00
IUUC-Yli-134503	Yarrowia lipolytica	48.86	5.00e-86	310.00
IUUC-Zma-135232	Zea mays	63.29	9.00e-105	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence