iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006664

UUCD1 version

UUC-ArT-00131

Ensembl Protein ID

AT1G49540.2

UniProt Accession

F4I1S7; O22044; Q0WVT2; Q9XIC1; ELP2_ARATH

Genbank Protein ID

AAD43147.1; AEE32440.1; BAE98766.1; BAA23158.1

Protein Name

Elongator complex protein 2; Elongator component 2; Protein GREEN NPR1 SEEDLING ON SA MEDIUM 1

Genbank Nucleotide ID

AC007504; CP002684; AK226658; AB000835

Gene Name

ELP2; GNS1; At1g49540; F13F21.2; F14J22.24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G49540	AT1G49540.2	AT1G49540.2
AT1G49540	AT1G49540.1	AT1G49540.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-46	153.2	221	261
UBD/Beta-Prp	4.60e-59	200.9	39	260

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..........sdtl...lvsGsdDgtikvWDl 30
           gHtd++++l+f          +      lvs+s D++i++W l
   Q: 221  GHTDWIRSLDFslplhtteeiP--NsimLVSSSQDKVIRIWKL 261
           8***********9997666554..04459************96 PP

UBD/Beta-Prp

   S: 74   rtikvwdlstgkcvhtlkghedsvlslsfsp...........sgdklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvv..hpdgnl 151
           +++ v+ ++t +++ tl gh++sv ++++ p           ++++l+sG++d +i +w+l+t    ++       +ls ++gv++++++  ++++ +
   Q: 39   NAVAVFCPKTAQILTTLPGHKASVNCTHWLPtskfafkakklDRQYLLSGDSDGIIILWELSTLNNDQQwrhvlqlPLSHKKGVTCITAYmvSETDAM 136
           67889999******************8888887777777877789****************999988889999**888888877777765214666** PP
   S: 152  lvsGslDrtvrlWdl.....ktgkllrtl....tgghtdsvysls.....fdsngkelvsgsldgtvklwdlq.tgec..vrtlnghtdnvksvrfs. 231
           ++s+s D++v++Wd+     +++++           +t+++  ls      ++ ++ l+ g+ld+++kl++ + tg+   v +l+ghtd+++s++fs 
   Q: 137  FASASSDGVVNVWDVsfpsqPSEECKVVCldsiCV-DTKAIVTLSlaelpQNPGRFALALGGLDNKIKLYSGErTGKFtsVCELKGHTDWIRSLDFSl 233
           ******************99444444444344255.9999999997776677777*****************9866666699**************** PP
   S: 232  ........pnderlvsgssDgsiriWd 250
                   pn+  lvs s+D++iriW 
   Q: 234  plhtteeiPNSIMLVSSSQDKVIRIWK 260
           **999*999*****************3 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (By similarity). Promotes organs development by modulating cell division rate. Prevents abscisic acid (ABA) signaling leading to stomatal closure and seedling growth inhibition. Involved in oxidative stress signaling. Prevents anthocyanins accumulation. Accelerator of defense gene induction required for rapid defense gene induction, and for the establishment of both basal and effector-triggered immunity (ETI), in a NPR1-independent manner, but is not required for systemic acquired resistance (SAR) establishment.

Protein Sequence
(Fasta)

MSENTKVEAK RVFIGAGCNR VVNNVSWGAS GLVSFGAQNA VAVFCPKTAQ ILTTLPGHKA 60
SVNCTHWLPT SKFAFKAKKL DRQYLLSGDS DGIIILWELS TLNNDQQWRH VLQLPLSHKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTCCCTG AATCTTAAGA ATTACTAATT CCCGGCGAGT TTTCCCGGCG GCGGCTAGAT 60
AATACTGGTT TCTGCCAGCA AGATCGAAGG AGATAAACTT CGTAATCAAA AAGTCTCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0938--Abscisic acid signaling pathway
KW-0012--Acyltransferase
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033588--C:Elongator holoenzyme complex
GO:0005634--C:nucleus
GO:0016746--F:transferase activity, transferring acyl groups
GO:0009738--P:abscisic acid-activated signaling pathway
GO:0006952--P:defense response
GO:0031538--P:negative regulation of anthocyanin metabolic process
GO:0008284--P:positive regulation of cell proliferation
GO:0031349--P:positive regulation of defense response
GO:2000024--P:regulation of leaf development
GO:0006355--P:regulation of transcription, DNA-templated
GO:0009737--P:response to abscisic acid
GO:0006979--P:response to oxidative stress
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT1G49540

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000056	Aegilops tauschii	59.05	0.00e+00	938.00
IUUC-Aml-002049	Ailuropoda melanoleuca	34.73	3.00e-103	369.00
IUUC-Atr-002456	Amborella trichopoda	57.55	0.00e+00	947.00
IUUC-Apl-004053	Anas platyrhynchos	36.84	2.00e-122	432.00
IUUC-Aca-004535	Anolis carolinensis	32.85	5.00e-110	391.00
IUUC-Aly-005746	Arabidopsis lyrata	95.70	0.00e+00	1589.00
IUUC-Ago-007971	Ashbya gossypii	28.11	3.00e-81	296.00
IUUC-Acl-008173	Aspergillus clavatus	32.21	5.00e-99	354.00
IUUC-Afl-008665	Aspergillus flavus	27.10	1.00e-36	147.00
IUUC-Afu-008976	Aspergillus fumigatus	30.52	5.00e-90	325.00
IUUC-Ani-009284	Aspergillus nidulans	30.53	1.00e-96	347.00
IUUC-Ang-009809	Aspergillus niger	30.57	3.00e-96	345.00
IUUC-Aor-009959	Aspergillus oryzae	31.38	2.00e-96	346.00
IUUC-Ate-010442	Aspergillus terreus	30.32	5.00e-95	341.00
IUUC-Ame-011409	Astyanax mexicanus	35.04	6.00e-119	421.00
IUUC-Bgr-012137	Blumeria graminis	32.60	6.00e-104	371.00
IUUC-Bta-012892	Bos taurus	35.44	1.00e-121	430.00
IUUC-Bci-013944	Botrytis cinerea	29.86	4.00e-94	338.00
IUUC-Bdi-014512	Brachypodium distachyon	59.69	0.00e+00	995.00
IUUC-Bol-015741	Brassica oleracea	89.77	0.00e+00	1516.00
IUUC-Bra-017367	Brassica rapa	89.42	0.00e+00	1503.00
IUUC-Cel-018712	Caenorhabditis elegans	32.61	2.00e-69	256.00
IUUC-Cja-018865	Callithrix jacchus	31.72	8.00e-109	387.00
IUUC-Cfa-021006	Canis familiaris	35.62	1.00e-120	426.00
IUUC-Cpo-021370	Cavia porcellus	35.08	1.00e-118	420.00
IUUC-Csa-023845	Chlorocebus sabaeus	34.78	2.00e-117	416.00
IUUC-Cho-024640	Choloepus hoffmanni	35.12	1.00e-75	277.00
IUUC-Cin-025772	Ciona intestinalis	32.93	3.00e-99	355.00
IUUC-Csv-025891	Ciona savignyi	33.69	3.00e-106	379.00
IUUC-Cgl-026443	Colletotrichum gloeosporioides	31.03	1.00e-93	337.00
IUUC-Cne-027081	Cryptococcus neoformans	30.64	4.00e-90	325.00
IUUC-Cme-027225	Cyanidioschyzon merolae	26.06	5.00e-48	185.00
IUUC-Dre-028250	Danio rerio	36.55	2.00e-119	422.00
IUUC-Dno-028847	Dasypus novemcinctus	35.15	9.00e-119	420.00
IUUC-Dor-030351	Dipodomys ordii	33.92	2.00e-113	402.00
IUUC-Dse-031317	Dothistroma septosporum	32.36	2.00e-89	322.00
IUUC-Dme-032019	Drosophila melanogaster	33.60	2.00e-124	439.00
IUUC-Ete-033194	Echinops telfairi	34.42	1.00e-67	250.00
IUUC-Eca-033779	Equus caballus	35.64	3.00e-121	429.00
IUUC-Eeu-034790	Erinaceus europaeus	33.91	3.00e-68	252.00
IUUC-Fca-036090	Felis catus	36.38	3.00e-116	412.00
IUUC-Fal-037663	Ficedula albicollis	38.22	5.00e-112	397.00
IUUC-Fox-037828	Fusarium oxysporum	31.52	4.00e-104	371.00
IUUC-Fso-038462	Fusarium solani	33.05	3.00e-104	372.00
IUUC-Gmo-039450	Gadus morhua	34.34	3.00e-123	435.00
IUUC-Ggr-040023	Gaeumannomyces graminis	29.53	2.00e-93	336.00
IUUC-Gga-040480	Gallus gallus	37.02	1.00e-132	467.00
IUUC-Gac-041544	Gasterosteus aculeatus	35.97	5.00e-127	447.00
IUUC-Gma-044048	Glycine max	65.52	0.00e+00	1130.00
IUUC-Ggo-045381	Gorilla gorilla	32.58	2.00e-107	382.00
IUUC-Hsa-046096	Homo sapiens	31.57	5.00e-110	391.00
IUUC-Hvu-047494	Hordeum vulgare	60.02	0.00e+00	1006.00
IUUC-Itr-048823	Ictidomys tridecemlineatus	32.33	7.00e-87	314.00
IUUC-Kpa-049241	Komagataella pastoris	30.85	4.00e-84	305.00
IUUC-Lch-050512	Latimeria chalumnae	38.77	8.00e-118	417.00
IUUC-Lpe-051448	Leersia perrieri	58.18	0.00e+00	975.00
IUUC-Loc-051882	Lepisosteus oculatus	35.55	5.00e-134	471.00
IUUC-Lma-053023	Leptosphaeria maculans	31.58	1.00e-97	350.00
IUUC-Laf-054519	Loxodonta africana	34.93	2.00e-119	422.00
IUUC-Mcc-055580	Macaca mulatta	33.05	2.00e-110	392.00
IUUC-Meu-056606	Macropus eugenii	45.06	9.00e-36	144.00
IUUC-Mor-057109	Magnaporthe oryzae	32.47	5.00e-107	381.00
IUUC-Mpo-057297	Magnaporthe poae	29.63	4.00e-92	332.00
IUUC-Mtr-058348	Medicago truncatula	64.45	0.00e+00	1097.00
IUUC-Mla-059159	Melampsora laricipopulina	28.64	5.00e-79	288.00
IUUC-Mga-059778	Meleagris gallopavo	36.25	1.00e-78	286.00
IUUC-Mvi-060447	Microbotryum violaceum	31.73	9.00e-97	347.00
IUUC-Mmr-061139	Microcebus murinus	33.30	7.00e-110	390.00
IUUC-Mdo-061866	Monodelphis domestica	34.63	1.00e-126	446.00
IUUC-Mmu-063390	Mus musculus	34.87	1.00e-117	416.00
IUUC-Mac-064693	Musa acuminata	62.22	0.00e+00	1052.00
IUUC-Mpu-066547	Mustela putorius furo	35.57	2.00e-113	402.00
IUUC-Mlu-067156	Myotis lucifugus	35.94	2.00e-122	432.00
IUUC-Nfi-068616	Neosartorya fischeri	31.40	4.00e-92	332.00
IUUC-Ncr-068915	Neurospora crassa	29.74	3.00e-91	329.00
IUUC-Nle-069958	Nomascus leucogenys	34.47	2.00e-112	399.00
IUUC-Opr-071093	Ochotona princeps	34.16	1.00e-54	207.00
IUUC-Ont-072178	Oreochromis niloticus	34.94	2.00e-124	439.00
IUUC-Oan-073667	Ornithorhynchus anatinus	34.49	2.00e-114	405.00
IUUC-Ocu-074662	Oryctolagus cuniculus	34.30	4.00e-119	421.00
IUUC-Oba-075577	Oryza barthii	59.64	0.00e+00	1004.00
IUUC-Obr-076566	Oryza brachyantha	60.24	0.00e+00	1002.00
IUUC-Ogl-077054	Oryza glaberrima	59.52	0.00e+00	1007.00
IUUC-Ogu-078846	Oryza glumaepatula	59.64	0.00e+00	1006.00
IUUC-Oin-079084	Oryza indica	59.16	0.00e+00	995.00
IUUC-Olo-080933	Oryza longistaminata	56.09	0.00e+00	880.00
IUUC-Ome-081500	Oryza meridionalis	57.09	0.00e+00	933.00
IUUC-Oni-082352	Oryza nivara	59.04	0.00e+00	992.00
IUUC-Opu-084116	Oryza punctata	58.00	0.00e+00	976.00
IUUC-Oru-085249	Oryza rufipogon	59.16	0.00e+00	995.00
IUUC-Osa-086270	Oryza sativa	59.16	0.00e+00	995.00
IUUC-Ola-086625	Oryzias latipes	33.57	3.00e-102	365.00
IUUC-Olu-087638	Ostreococcus lucimarinus	33.71	2.00e-93	335.00
IUUC-Oga-088634	Otolemur garnettii	34.59	5.00e-95	341.00
IUUC-Oar-089475	Ovis aries	35.62	3.00e-120	426.00
IUUC-Ptr-091131	Pan troglodytes	34.20	6.00e-117	414.00
IUUC-Pan-092869	Papio anubis	35.00	1.00e-116	413.00
IUUC-Psi-093146	Pelodiscus sinensis	37.37	1.00e-112	399.00
IUUC-Pma-094479	Petromyzon marinus	38.70	3.00e-106	379.00
IUUC-Pno-095061	Phaeosphaeria nodorum	28.03	6.00e-57	214.00
IUUC-Ppa-095618	Physcomitrella patens	47.56	0.00e+00	759.00
IUUC-Pfo-096816	Poecilia formosa	36.23	4.00e-130	458.00
IUUC-Pab-097548	Pongo abelii	34.17	2.00e-116	412.00
IUUC-Pop-099643	Populus trichocarpa	68.47	0.00e+00	1164.00
IUUC-Pca-100983	Procavia capensis	34.51	7.00e-58	218.00
IUUC-Ppe-101301	Prunus persica	67.07	0.00e+00	1126.00
IUUC-Pva-102460	Pteropus vampyrus	35.14	7.00e-115	407.00
IUUC-Pgr-103507	Puccinia graminis	29.95	1.00e-87	317.00
IUUC-Ptt-103892	Puccinia triticina	30.38	2.00e-78	286.00
IUUC-Pte-104283	Pyrenophora teres	31.05	1.00e-94	340.00
IUUC-Pyt-104465	Pyrenophora triticirepentis	31.11	2.00e-94	340.00
IUUC-Rno-105842	Rattus norvegicus	35.42	8.00e-121	427.00
IUUC-Sce-106459	Saccharomyces cerevisiae	28.25	2.00e-79	289.00
IUUC-Sha-106586	Sarcophilus harrisii	30.80	6.00e-74	271.00
IUUC-Sja-107868	Schizosaccharomyces japonicus	31.04	1.00e-89	323.00
IUUC-Spo-108302	Schizosaccharomyces pombe	29.91	2.00e-89	323.00
IUUC-Smo-108861	Selaginella moellendorffii	47.85	0.00e+00	760.00
IUUC-Sit-109915	Setaria italica	59.72	0.00e+00	1015.00
IUUC-Sly-111714	Solanum lycopersicum	65.99	0.00e+00	1119.00
IUUC-Stu-112631	Solanum tuberosum	66.51	0.00e+00	1137.00
IUUC-Sar-113200	Sorex araneus	32.65	1.00e-94	340.00
IUUC-Sbi-114582	Sorghum bicolor	59.62	0.00e+00	1013.00
IUUC-Sre-115001	Sporisorium reilianum	26.68	1.00e-40	161.00
IUUC-Ssc-115519	Sus scrofa	35.81	2.00e-124	439.00
IUUC-Tgu-116987	Taeniopygia guttata	36.31	4.00e-121	428.00
IUUC-Tru-118476	Takifugu rubripes	34.74	2.00e-117	416.00
IUUC-Tsy-119230	Tarsius syrichta	34.13	4.00e-46	179.00
IUUC-Tni-120448	Tetraodon nigroviridis	32.65	1.00e-44	174.00
IUUC-Tca-121650	Theobroma cacao	68.28	0.00e+00	1182.00
IUUC-Tre-122086	Trichoderma reesei	32.14	1.00e-94	340.00
IUUC-Tvi-122397	Trichoderma virens	31.57	5.00e-88	318.00
IUUC-Tae-123972	Triticum aestivum	59.93	0.00e+00	1004.00
IUUC-Tur-126578	Triticum urartu	59.81	0.00e+00	1001.00
IUUC-Tme-126927	Tuber melanosporum	30.79	1.00e-92	333.00
IUUC-Tbe-127922	Tupaia belangeri	39.82	4.00e-39	155.00
IUUC-Ttr-128918	Tursiops truncatus	35.67	4.00e-121	428.00
IUUC-Uma-129474	Ustilago maydis	25.80	9.00e-41	162.00
IUUC-Vda-129944	Verticillium dahliae	31.00	3.00e-93	335.00
IUUC-Vpa-130693	Vicugna pacos	37.64	5.00e-117	414.00
IUUC-Vvi-130949	Vitis vinifera	67.70	0.00e+00	1164.00
IUUC-Xtr-132639	Xenopus tropicalis	32.45	4.00e-116	412.00
IUUC-Xma-134223	Xiphophorus maculatus	37.03	3.00e-80	291.00
IUUC-Yli-134601	Yarrowia lipolytica	32.06	6.00e-89	321.00
IUUC-Zma-135952	Zea mays	60.12	0.00e+00	1010.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence