iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093907

Ensembl Protein ID

ENSPSIP00000020027.1

UniProt Accession

K7GIB6; K7GIB6_PELSI

Genbank Protein ID

ENSPSIP00000020027

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01141119

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000017741.1	ENSPSIT00000020121.1	ENSPSIP00000020027.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.90e-29	98.7	602	639
UBD/Beta-Prp	9.10e-45	153.1	458	674

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d vt+la  ++  +l sGs+D++i++W+l + ++++
   Q: 602  HLDAVTSLAVdPNgLYLMSGSHDCSIRLWNLESKTCIQ 639
           99*********77799***************9999987 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc.vhtlk.....ghedsvlslsfspsgdklvsGshdrtirvwdletg 126
           l   ++gh+++v+ + +s   + l+++s D+ti++w  s   + + +++     g  +sv ++s++p  +++v+        ++++et+
   Q: 458  LRGAFEGHTDAVWGLVYSGAHQRLLSCSADGTIRLWKTSEIAPaLNIFNdnkemGIPSSVDLVSSDP--SHMVASFTSGHTCLFNMETR 544
           344569******************************7774444044444544666666777777777..44444444455567****** PP
   S: 127  qclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           q + +        ++++  +n vv+hp+  + ++++ Dr ++++d +tgkl++ +   h d+v+sl++d+ng +l+sgs+d +++lw+l
   Q: 545  QQILTlesnidNTANTSCQINRVVSHPTLPISITAHEDRHIKFYDNNTGKLIHAMVA-HLDAVTSLAVDPNGLYLMSGSHDCSIRLWNL 632
           ****99999776666667789999***99**************************98.******************************* PP
   S: 210  qtgecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 633  ESKTCIQEFTAHRkkfdESIHDVAFHPSKCYIASAGADALAK 674
           *************9999999****************997655 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MLEYALKQER AKYHKLKYGT ELNQGDMKPP NYDSDEGNDT EVQPQQNSQL IWKQGRQLLR 60
QYLQEVGYTD TILDVKSKRV RALLGLSNDA SDRENDKNQE SMVNGTEVEI KENAMIGKPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAATGAGCA GGCTGGGGAT GCAGGGTTTT GGTGGGGGGT CCGTGAGAGG GTGGGGTCTG 60
GGCATGATGA GGTGGGGGGC ACTCACTTTC GTATCACGTT GCAGGCACTG TGTAACATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	87.74	0.00e+00	1140.00
IUUC-Apl-003927	Anas platyrhynchos	91.59	0.00e+00	1115.00
IUUC-Aca-004933	Anolis carolinensis	83.99	0.00e+00	1135.00
IUUC-Ame-010997	Astyanax mexicanus	74.20	0.00e+00	942.00
IUUC-Bgr-012143	Blumeria graminis	25.11	1.00e-35	144.00
IUUC-Bta-013077	Bos taurus	88.18	0.00e+00	1141.00
IUUC-Cja-018973	Callithrix jacchus	88.63	0.00e+00	1145.00
IUUC-Cfa-020988	Canis familiaris	84.34	0.00e+00	1083.00
IUUC-Cpo-022496	Cavia porcellus	87.59	0.00e+00	1147.00
IUUC-Csa-023829	Chlorocebus sabaeus	88.33	0.00e+00	1143.00
IUUC-Dre-028560	Danio rerio	69.32	0.00e+00	855.00
IUUC-Dno-029742	Dasypus novemcinctus	82.13	0.00e+00	1082.00
IUUC-Dor-030721	Dipodomys ordii	79.17	0.00e+00	1014.00
IUUC-Dse-031486	Dothistroma septosporum	28.05	5.00e-38	152.00
IUUC-Eca-033760	Equus caballus	87.89	0.00e+00	1135.00
IUUC-Eeu-034953	Erinaceus europaeus	89.58	0.00e+00	711.00
IUUC-Fca-036530	Felis catus	87.44	0.00e+00	1138.00
IUUC-Fal-037353	Ficedula albicollis	85.79	0.00e+00	930.00
IUUC-Gmo-039094	Gadus morhua	70.15	3.00e-161	561.00
IUUC-Gga-040132	Gallus gallus	91.73	0.00e+00	1116.00
IUUC-Gac-041713	Gasterosteus aculeatus	73.70	0.00e+00	925.00
IUUC-Ggo-045455	Gorilla gorilla	78.27	0.00e+00	958.00
IUUC-Hsa-046415	Homo sapiens	88.18	0.00e+00	1142.00
IUUC-Lch-050475	Latimeria chalumnae	83.95	0.00e+00	1070.00
IUUC-Loc-051859	Lepisosteus oculatus	79.33	0.00e+00	1019.00
IUUC-Laf-053537	Loxodonta africana	88.33	0.00e+00	1158.00
IUUC-Mcc-055817	Macaca mulatta	88.33	0.00e+00	1143.00
IUUC-Meu-055946	Macropus eugenii	63.61	0.00e+00	723.00
IUUC-Mla-058988	Melampsora laricipopulina	35.33	3.00e-64	240.00
IUUC-Mga-059694	Meleagris gallopavo	91.29	0.00e+00	1110.00
IUUC-Mmr-060768	Microcebus murinus	88.18	0.00e+00	1142.00
IUUC-Mdo-061901	Monodelphis domestica	83.14	0.00e+00	1118.00
IUUC-Mmu-064154	Mus musculus	86.12	0.00e+00	1124.00
IUUC-Mpu-065827	Mustela putorius furo	82.44	0.00e+00	1129.00
IUUC-Mlu-067102	Myotis lucifugus	87.59	0.00e+00	1133.00
IUUC-Ncr-068831	Neurospora crassa	39.60	6.00e-22	99.40
IUUC-Nle-070008	Nomascus leucogenys	88.63	0.00e+00	1145.00
IUUC-Ont-072025	Oreochromis niloticus	74.09	0.00e+00	918.00
IUUC-Oan-072950	Ornithorhynchus anatinus	89.22	0.00e+00	1149.00
IUUC-Ocu-074316	Oryctolagus cuniculus	88.05	0.00e+00	1129.00
IUUC-Ola-087279	Oryzias latipes	71.47	0.00e+00	891.00
IUUC-Oga-088284	Otolemur garnettii	87.59	0.00e+00	1139.00
IUUC-Oar-090304	Ovis aries	88.33	0.00e+00	1144.00
IUUC-Ptr-091052	Pan troglodytes	88.33	0.00e+00	1144.00
IUUC-Pan-092270	Papio anubis	84.83	0.00e+00	1107.00
IUUC-Pfo-097042	Poecilia formosa	72.82	0.00e+00	994.00
IUUC-Pab-098110	Pongo abelii	88.33	0.00e+00	1144.00
IUUC-Pca-100266	Procavia capensis	74.91	0.00e+00	770.00
IUUC-Pva-102824	Pteropus vampyrus	86.12	0.00e+00	1095.00
IUUC-Pgr-103483	Puccinia graminis	37.57	1.00e-57	218.00
IUUC-Rno-105638	Rattus norvegicus	87.30	0.00e+00	1137.00
IUUC-Sha-107004	Sarcophilus harrisii	83.53	0.00e+00	1040.00
IUUC-Ssc-115280	Sus scrofa	88.48	0.00e+00	1147.00
IUUC-Tgu-116759	Taeniopygia guttata	91.73	0.00e+00	1131.00
IUUC-Tru-117944	Takifugu rubripes	74.38	0.00e+00	927.00
IUUC-Tsy-119405	Tarsius syrichta	77.70	0.00e+00	949.00
IUUC-Tni-120571	Tetraodon nigroviridis	73.44	0.00e+00	927.00
IUUC-Vpa-130294	Vicugna pacos	87.74	0.00e+00	1127.00
IUUC-Xtr-132253	Xenopus tropicalis	70.00	0.00e+00	767.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence