iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119921

UUCD1 version

UUC-TeN-01134

Ensembl Protein ID

ENSTNIP00000007622.1

UniProt Accession

H3CH94; H3CH94_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000004957.1	ENSTNIT00000000776.1	ENSTNIP00000003712.1
ENSTNIG00000004957.1	ENSTNIT00000007782.1	ENSTNIP00000007622.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-114	382.5	535	1255

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++l+  ++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 535  TGLVNLGNTCFMNSVIQSLSNTRELRDYFLDrAFEGEINCSNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 621
           7******************************8999**************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++   dea++++k++n+s+i+dlFqgq+ks+++c+ c +vs +++pfl
   Q: 622  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDgrlDEVVADEAWQRHKMRNDSFIVDLFQGQFKSKLVCPMCSKVSITFDPFL 708
           ********************************99982222344555***************************************** PP
   S: 171  dlslpvpgkeetkke........................................................................ 185
           +l++p+p+k++                                                                            
   Q: 709  YLPVPLPQKQKVLSVyyfakephkkpikfsvsvskenshtaevlesisrsvrvkaenlrlaevgknrfqrmflpshsldtvsssdml 795
           **********76444************************************************************************ PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 796  fcfellskemakekvvllrvqqklqvpnipiskcaaclkpptseedklkrctrcyrvgycnqvcqrthwpnhkslcrpntenvglpf 882
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 883  lvsvpesrlcysrlsqllegysrfsvdvfqppfhsgrtspdsrcagdlpvlpagcpepgrpsdqalcsssagsadpepdgpslqpgq 969
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 970  qqcaqasappageqfssvsccsfdphseketscektvrpeaavtgyqqpsevssahasqffislldsnnkeqrldekedalanlped 1056
           *************************************************************************************** PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                     +l++cL+ ftk+e l  e+++yc+kc++++ea+k+l l++lP+vL
   Q: 1057 atlelvwknnerlkeyvlvsskdldyeedpsslsetaraghfTLEQCLNLFTKPEVLAPEEAWYCPKCQQHREASKQLLLWRLPNVL 1143
           *************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk........Wll 308
           i++LkRfsf++  +++ kin+ v+fp++ Ldls+fc+  +++  ++  Y+L+av++H+G++ +GHY+ay++  ++k        W l
   Q: 1144 IIQLKRFSFRSFIWRD-KINDMVDFPIRnLDLSRFCIGMKDEM-QQPVYDLYAVINHYGGMIGGHYTAYARLPSDKnsqrsdvgWRL 1228
           ************8886.*********************77776.59*************************9444444567788*** PP
   S: 309  fdDskVtevkeeevleetgstaYvlfYkrr 338
           fdDs+Vt v+e++v++   + aYvlfY+rr
   Q: 1229 FDDSTVTMVEESQVVT---RYAYVLFYRRR 1255
           ****************...********996 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

QRAGRRRSGP PRGVPAEASS KKKQKDRANQ ESREAKRAVA VVDAVIAEVR KDVFVDWKQN 60
VNEVTVRLRC GDGIQRKEDV STSFTDKSCH VSFPDGRQWS CQLQEEIEAS CSRVQYREKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCGCGCTG GGCGGCGACG CAGCGGCCCA CCGCGGGGGG TCCCAGCAGA GGCGAGGTCA 60
TGGCAGGGAG GCGGCCTCCG ATCTGTCCTC CTGCAGCAGT AAAAAGAAGC AGAAAGACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND

PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2

Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0046872--F:metal ion binding
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001999	Ailuropoda melanoleuca	68.69	0.00e+00	1344.00
IUUC-Apl-003368	Anas platyrhynchos	60.55	0.00e+00	1429.00
IUUC-Aca-004267	Anolis carolinensis	69.77	0.00e+00	1339.00
IUUC-Ame-010970	Astyanax mexicanus	76.53	0.00e+00	1474.00
IUUC-Bta-012905	Bos taurus	69.39	0.00e+00	1315.00
IUUC-Cel-018257	Caenorhabditis elegans	43.66	4.00e-95	343.00
IUUC-Cja-018789	Callithrix jacchus	67.36	0.00e+00	1350.00
IUUC-Cfa-021004	Canis familiaris	68.90	0.00e+00	1317.00
IUUC-Cpo-021529	Cavia porcellus	58.32	0.00e+00	1399.00
IUUC-Csa-024035	Chlorocebus sabaeus	70.47	0.00e+00	1353.00
IUUC-Cho-025036	Choloepus hoffmanni	68.45	1.00e-174	607.00
IUUC-Cin-025451	Ciona intestinalis	40.53	5.00e-86	312.00
IUUC-Dre-028556	Danio rerio	71.32	0.00e+00	1479.00
IUUC-Dno-029240	Dasypus novemcinctus	56.71	0.00e+00	1293.00
IUUC-Dor-030495	Dipodomys ordii	64.49	0.00e+00	846.00
IUUC-Ete-032741	Echinops telfairi	68.86	0.00e+00	1321.00
IUUC-Eca-033661	Equus caballus	66.51	0.00e+00	1346.00
IUUC-Eeu-034648	Erinaceus europaeus	73.47	5.00e-160	558.00
IUUC-Fca-035646	Felis catus	70.47	0.00e+00	1312.00
IUUC-Fal-037094	Ficedula albicollis	65.53	0.00e+00	1391.00
IUUC-Gmo-038869	Gadus morhua	74.57	0.00e+00	1434.00
IUUC-Gga-041170	Gallus gallus	65.62	0.00e+00	1376.00
IUUC-Gac-041901	Gasterosteus aculeatus	78.57	0.00e+00	1563.00
IUUC-Ggo-044708	Gorilla gorilla	66.23	0.00e+00	1355.00
IUUC-Hsa-046791	Homo sapiens	66.42	0.00e+00	1346.00
IUUC-Itr-048892	Ictidomys tridecemlineatus	58.87	0.00e+00	1355.00
IUUC-Lch-050456	Latimeria chalumnae	59.96	0.00e+00	1070.00
IUUC-Loc-052861	Lepisosteus oculatus	60.51	0.00e+00	1190.00
IUUC-Laf-053788	Loxodonta africana	66.67	0.00e+00	1331.00
IUUC-Mcc-055693	Macaca mulatta	70.26	0.00e+00	1346.00
IUUC-Meu-055921	Macropus eugenii	69.79	0.00e+00	1146.00
IUUC-Mga-059879	Meleagris gallopavo	58.70	0.00e+00	1456.00
IUUC-Mmr-060802	Microcebus murinus	58.73	0.00e+00	1409.00
IUUC-Mdo-061856	Monodelphis domestica	66.54	0.00e+00	1320.00
IUUC-Mmu-063874	Mus musculus	58.75	0.00e+00	1432.00
IUUC-Mpu-066166	Mustela putorius furo	69.29	0.00e+00	1312.00
IUUC-Nle-070161	Nomascus leucogenys	66.57	0.00e+00	1348.00
IUUC-Opr-071015	Ochotona princeps	69.95	0.00e+00	1303.00
IUUC-Ont-072308	Oreochromis niloticus	82.96	0.00e+00	1691.00
IUUC-Oan-072723	Ornithorhynchus anatinus	62.91	0.00e+00	1315.00
IUUC-Ocu-073938	Oryctolagus cuniculus	70.05	0.00e+00	1315.00
IUUC-Ola-086375	Oryzias latipes	82.71	0.00e+00	1608.00
IUUC-Oga-088297	Otolemur garnettii	66.95	0.00e+00	1333.00
IUUC-Oar-089675	Ovis aries	68.93	0.00e+00	1179.00
IUUC-Ptr-091621	Pan troglodytes	66.32	0.00e+00	1343.00
IUUC-Pan-092118	Papio anubis	70.47	0.00e+00	1353.00
IUUC-Pma-094154	Petromyzon marinus	49.76	3.00e-110	392.00
IUUC-Pfo-097246	Poecilia formosa	73.64	0.00e+00	1751.00
IUUC-Pab-098551	Pongo abelii	66.38	0.00e+00	1329.00
IUUC-Pca-100158	Procavia capensis	63.88	0.00e+00	1248.00
IUUC-Pva-103160	Pteropus vampyrus	58.26	0.00e+00	1408.00
IUUC-Rno-105355	Rattus norvegicus	57.64	0.00e+00	1417.00
IUUC-Sha-107057	Sarcophilus harrisii	71.31	0.00e+00	1333.00
IUUC-Sar-113011	Sorex araneus	60.96	0.00e+00	953.00
IUUC-Ssc-115761	Sus scrofa	60.67	0.00e+00	1387.00
IUUC-Tgu-116956	Taeniopygia guttata	58.49	0.00e+00	769.00
IUUC-Tru-118739	Takifugu rubripes	88.45	0.00e+00	1837.00
IUUC-Tsy-118827	Tarsius syrichta	75.16	0.00e+00	656.00
IUUC-Tbe-128017	Tupaia belangeri	63.79	0.00e+00	1280.00
IUUC-Ttr-128869	Tursiops truncatus	58.17	0.00e+00	1404.00
IUUC-Vpa-130427	Vicugna pacos	63.40	4.00e-173	602.00
IUUC-Xtr-132734	Xenopus tropicalis	69.95	0.00e+00	1352.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence