iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117594

Ensembl Protein ID

ENSTRUP00000007128.1

UniProt Accession

H2S406; H2S406_TAKRU

Protein Name

Tyrosine-protein kinase

Gene Name

yes1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000003054.1	ENSTRUT00000007173.1	ENSTRUP00000007128.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-14	55.5	104	159

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L+++kGd  ++i  ++++++W+++ + ++g+ G +P+n+v+ ++
   Q: 104  FVALYDYEARTSDDLSFTKGDRFQII--NNTEGDWWEARSITTGRTGYIPSNYVAPAD 159
           679***********************..8999**********************9875 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MGCIKSKEEK GPTMKYRPEN SMMADPNATA ASQTGHYGPD PTQLQQNQVP SSSSGNVGVN 60
FNHSITPFGG SSSAMTPFGG VSSSFTGPVS NSFSGAVSSG VTFFVALYDY EARTSDDLSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGATGCA TAAAGAGCAA GGAGGAAAAA GGCCCCACTA TGAAGTACCG TCCAGAGAAC 60
TCCATGATGG CAGACCCCAA CGCCACCGCC GCCTCTCAGA CGGGTCATTA CGGGCCGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

tru:101078472

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	84.99	0.00e+00	945.00
IUUC-Aca-004255	Anolis carolinensis	85.48	0.00e+00	971.00
IUUC-Bta-013503	Bos taurus	84.39	0.00e+00	932.00
IUUC-Cja-019694	Callithrix jacchus	84.60	0.00e+00	936.00
IUUC-Cfa-020402	Canis familiaris	85.33	0.00e+00	952.00
IUUC-Cpo-022506	Cavia porcellus	84.60	0.00e+00	940.00
IUUC-Csa-023713	Chlorocebus sabaeus	85.14	0.00e+00	939.00
IUUC-Dno-029897	Dasypus novemcinctus	83.13	0.00e+00	823.00
IUUC-Eca-034157	Equus caballus	84.96	0.00e+00	949.00
IUUC-Fca-036233	Felis catus	85.14	0.00e+00	971.00
IUUC-Fal-037461	Ficedula albicollis	85.51	0.00e+00	975.00
IUUC-Gac-041435	Gasterosteus aculeatus	90.58	0.00e+00	971.00
IUUC-Hsa-047010	Homo sapiens	85.33	0.00e+00	954.00
IUUC-Lch-050239	Latimeria chalumnae	85.69	0.00e+00	983.00
IUUC-Laf-053517	Loxodonta africana	83.70	0.00e+00	927.00
IUUC-Mcc-055626	Macaca mulatta	85.14	0.00e+00	939.00
IUUC-Meu-056155	Macropus eugenii	76.05	0.00e+00	722.00
IUUC-Mmr-061652	Microcebus murinus	83.15	0.00e+00	936.00
IUUC-Mdo-062963	Monodelphis domestica	83.88	0.00e+00	941.00
IUUC-Mmu-064128	Mus musculus	84.60	0.00e+00	954.00
IUUC-Mpu-065906	Mustela putorius furo	84.96	0.00e+00	949.00
IUUC-Mlu-067035	Myotis lucifugus	84.32	0.00e+00	940.00
IUUC-Nle-069041	Nomascus leucogenys	81.34	0.00e+00	896.00
IUUC-Opr-070299	Ochotona princeps	76.77	0.00e+00	832.00
IUUC-Ont-072127	Oreochromis niloticus	90.74	0.00e+00	983.00
IUUC-Oan-072997	Ornithorhynchus anatinus	92.59	0.00e+00	902.00
IUUC-Ocu-074171	Oryctolagus cuniculus	84.24	0.00e+00	945.00
IUUC-Ola-086619	Oryzias latipes	90.04	0.00e+00	1045.00
IUUC-Oga-087957	Otolemur garnettii	82.97	0.00e+00	931.00
IUUC-Oar-089670	Ovis aries	83.12	0.00e+00	939.00
IUUC-Ptr-091352	Pan troglodytes	85.33	0.00e+00	954.00
IUUC-Pan-092202	Papio anubis	85.14	0.00e+00	939.00
IUUC-Pfo-096137	Poecilia formosa	90.22	0.00e+00	1027.00
IUUC-Pab-098301	Pongo abelii	90.14	0.00e+00	902.00
IUUC-Pop-099554	Populus trichocarpa	31.51	2.00e-23	104.00
IUUC-Pva-102592	Pteropus vampyrus	79.53	0.00e+00	888.00
IUUC-Rno-105544	Rattus norvegicus	82.97	0.00e+00	932.00
IUUC-Sar-113364	Sorex araneus	80.76	0.00e+00	876.00
IUUC-Tgu-117380	Taeniopygia guttata	85.51	0.00e+00	975.00
IUUC-Tni-120433	Tetraodon nigroviridis	97.29	0.00e+00	1108.00
IUUC-Tae-122931	Triticum aestivum	33.33	2.00e-18	87.80
IUUC-Ttr-128893	Tursiops truncatus	84.96	0.00e+00	950.00
IUUC-Vpa-130060	Vicugna pacos	83.70	0.00e+00	935.00
IUUC-Xtr-132322	Xenopus tropicalis	84.96	0.00e+00	963.00
IUUC-Xma-134012	Xiphophorus maculatus	90.04	0.00e+00	1055.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence