iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118581

UUCD1 version

UUC-TaR-00709

Ensembl Protein ID

ENSTRUP00000033727.1

UniProt Accession

H2U9W1; H2U9W1_TAKRU

Protein Name

Uncharacterized protein

Gene Name

tbl1xr1a; LOC101072205

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000013251.1	ENSTRUT00000033853.1	ENSTRUP00000033727.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-52	174.6	348	386
UBD/Beta-Prp	1.30e-65	222.8	163	332

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+++++ ++ +ll+s+sdD t+k+W+++++ +++
   Q: 348  GHTNEVNAIKWdPTgNLLASCSDDMTLKIWSMKQDSCVH 386
           8***********778********************9986 PP

UBD/Beta-Prp

   S: 87   vhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.............tlsghdgvvncvvvhpdgnllvsGslDrtvr 162
            ++l+ghe++v  ++++p +d l+sGs d+t+r+w+l++++ +++              + + ++ v+++ ++++g ll++Gs+D++ r
   Q: 163  AMVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSSSSStqlvlrhcireggQDVPSNKDVTSLDWNSEGTLLATGSYDGFAR 251
           5899***************************************999************89999999*********************** PP
   S: 163  lWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsi 246
           +W  k g+l  tl + h++++  l+++++g++++s++ d+t ++wd +tge  +++  h+++ ++v+    ++ ++s+s D  i
   Q: 252  IW-TKDGNLASTLGQ-HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCI 332
           **.88********76.***************************************************88.77778888888776 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV 60
EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKMAQQQAAG AAPASATGGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCATTA GCAGTGATGA GGTCAACTTC CTGGTCTACA GATACCTACA GGAGTCAGGT 60
ATTCCCTTCA CGTCTATTAG ACTTATGTCT CAACTGTTCA ATAATTCTAT GATCATAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

tru:101072205

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	60.00	3.00e-54	203.00
IUUC-Aml-001717	Ailuropoda melanoleuca	92.82	0.00e+00	930.00
IUUC-Apl-003708	Anas platyrhynchos	95.15	0.00e+00	890.00
IUUC-Aca-004611	Anolis carolinensis	94.95	0.00e+00	927.00
IUUC-Bta-012418	Bos taurus	92.43	0.00e+00	949.00
IUUC-Cja-018832	Callithrix jacchus	92.82	0.00e+00	931.00
IUUC-Cfa-020029	Canis familiaris	92.62	0.00e+00	929.00
IUUC-Cpo-022080	Cavia porcellus	90.31	0.00e+00	886.00
IUUC-Csa-024075	Chlorocebus sabaeus	92.82	0.00e+00	929.00
IUUC-Cho-024872	Choloepus hoffmanni	90.21	1.00e-104	373.00
IUUC-Cin-025704	Ciona intestinalis	72.12	0.00e+00	788.00
IUUC-Dre-028075	Danio rerio	95.92	0.00e+00	931.00
IUUC-Dno-029196	Dasypus novemcinctus	92.82	0.00e+00	931.00
IUUC-Dor-030732	Dipodomys ordii	96.43	0.00e+00	709.00
IUUC-Eeu-034952	Erinaceus europaeus	82.97	0.00e+00	805.00
IUUC-Fca-035734	Felis catus	92.62	0.00e+00	930.00
IUUC-Fal-037185	Ficedula albicollis	95.34	0.00e+00	930.00
IUUC-Gga-041161	Gallus gallus	95.53	0.00e+00	931.00
IUUC-Gac-041844	Gasterosteus aculeatus	97.86	0.00e+00	969.00
IUUC-Ggo-044882	Gorilla gorilla	92.82	0.00e+00	929.00
IUUC-Hsa-046488	Homo sapiens	92.82	0.00e+00	929.00
IUUC-Itr-047958	Ictidomys tridecemlineatus	97.54	0.00e+00	719.00
IUUC-Lch-050672	Latimeria chalumnae	94.56	0.00e+00	961.00
IUUC-Loc-052030	Lepisosteus oculatus	94.40	0.00e+00	953.00
IUUC-Laf-054280	Loxodonta africana	94.56	0.00e+00	949.00
IUUC-Mcc-055203	Macaca mulatta	92.82	0.00e+00	928.00
IUUC-Meu-056563	Macropus eugenii	97.06	1.00e-133	469.00
IUUC-Mga-059660	Meleagris gallopavo	95.53	0.00e+00	931.00
IUUC-Mmr-060925	Microcebus murinus	91.63	0.00e+00	890.00
IUUC-Mdo-062078	Monodelphis domestica	94.76	0.00e+00	932.00
IUUC-Mmu-063603	Mus musculus	92.43	0.00e+00	931.00
IUUC-Mpu-066741	Mustela putorius furo	92.62	0.00e+00	929.00
IUUC-Mlu-068152	Myotis lucifugus	92.62	0.00e+00	923.00
IUUC-Nle-069229	Nomascus leucogenys	92.82	0.00e+00	929.00
IUUC-Opr-070277	Ochotona princeps	84.45	0.00e+00	783.00
IUUC-Ont-072623	Oreochromis niloticus	97.48	0.00e+00	967.00
IUUC-Ocu-074280	Oryctolagus cuniculus	91.03	0.00e+00	920.00
IUUC-Ola-087365	Oryzias latipes	97.48	0.00e+00	964.00
IUUC-Oga-088357	Otolemur garnettii	91.46	0.00e+00	879.00
IUUC-Oar-089214	Ovis aries	92.62	0.00e+00	952.00
IUUC-Ptr-091532	Pan troglodytes	92.82	0.00e+00	929.00
IUUC-Pan-091927	Papio anubis	92.82	0.00e+00	929.00
IUUC-Psi-093941	Pelodiscus sinensis	90.15	0.00e+00	917.00
IUUC-Pma-094105	Petromyzon marinus	65.31	2.00e-100	358.00
IUUC-Pfo-096158	Poecilia formosa	97.67	0.00e+00	966.00
IUUC-Pab-098705	Pongo abelii	92.82	0.00e+00	929.00
IUUC-Pca-100256	Procavia capensis	94.51	0.00e+00	915.00
IUUC-Pva-102616	Pteropus vampyrus	92.72	0.00e+00	911.00
IUUC-Rno-105411	Rattus norvegicus	92.43	0.00e+00	929.00
IUUC-Sce-106132	Saccharomyces cerevisiae	24.73	3.00e-41	162.00
IUUC-Sha-106636	Sarcophilus harrisii	94.95	0.00e+00	932.00
IUUC-Smo-109301	Selaginella moellendorffii	63.76	6.00e-142	497.00
IUUC-Sly-111042	Solanum lycopersicum	50.39	1.00e-150	526.00
IUUC-Sar-112971	Sorex araneus	84.74	0.00e+00	847.00
IUUC-Sre-115175	Sporisorium reilianum	38.59	1.00e-58	221.00
IUUC-Ssc-115695	Sus scrofa	90.87	0.00e+00	908.00
IUUC-Tgu-117009	Taeniopygia guttata	95.46	0.00e+00	914.00
IUUC-Tsy-119424	Tarsius syrichta	75.59	0.00e+00	705.00
IUUC-Tni-119986	Tetraodon nigroviridis	99.61	0.00e+00	985.00
IUUC-Tbe-127665	Tupaia belangeri	79.77	0.00e+00	799.00
IUUC-Uma-129469	Ustilago maydis	42.75	4.00e-58	219.00
IUUC-Vpa-130768	Vicugna pacos	92.35	0.00e+00	915.00
IUUC-Xtr-132842	Xenopus tropicalis	90.67	0.00e+00	889.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence