iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068093

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02005597

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000029988.1	ENSMLUT00000030330.1	ENSMLUP00000019790.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.20e-09	35.9	10	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +       +   s  f+CP+Cr
   Q: 10   CPICCSLFDD-PRVLPCSHNFCKKCLEGIlegtGRNSLWRSSPFKCPTCR 58
           ********99.**************955555554444559999******8 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MELLEEDLTC PICCSLFDDP RVLPCSHNFC KKCLEGILEG TGRNSLWRSS PFKCPTCRKE 60
TSASGVNSLQ VNYSLKGIVE KYNKIKISPK MPVCKGHLGQ PLNIFCLTDM QLICGICATR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCTGC TTGAAGAAGA TCTTACGTGC CCAATCTGTT GCAGTCTGTT TGATGATCCT 60
CGAGTTTTGC CTTGCTCTCA CAACTTTTGC AAAAAATGCT TAGAAGGGAT CTTAGAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	95.09	0.00e+00	739.00
IUUC-Apl-004168	Anas platyrhynchos	75.31	4.00e-179	620.00
IUUC-Aca-004395	Anolis carolinensis	68.95	8.00e-165	573.00
IUUC-Ame-011325	Astyanax mexicanus	46.75	6.00e-68	251.00
IUUC-Bta-012613	Bos taurus	92.38	0.00e+00	717.00
IUUC-Cja-018856	Callithrix jacchus	91.89	0.00e+00	773.00
IUUC-Cfa-021019	Canis familiaris	93.37	0.00e+00	727.00
IUUC-Cpo-021845	Cavia porcellus	90.66	0.00e+00	707.00
IUUC-Csa-023380	Chlorocebus sabaeus	92.14	0.00e+00	724.00
IUUC-Cho-024733	Choloepus hoffmanni	82.81	2.00e-88	319.00
IUUC-Dre-028675	Danio rerio	59.20	3.00e-107	382.00
IUUC-Dno-030018	Dasypus novemcinctus	90.20	0.00e+00	723.00
IUUC-Dor-030599	Dipodomys ordii	89.14	1.00e-127	448.00
IUUC-Ete-033134	Echinops telfairi	87.25	0.00e+00	707.00
IUUC-Eca-033931	Equus caballus	94.84	0.00e+00	723.00
IUUC-Eeu-034903	Erinaceus europaeus	90.91	0.00e+00	705.00
IUUC-Fca-035642	Felis catus	94.10	0.00e+00	724.00
IUUC-Fal-037108	Ficedula albicollis	75.74	0.00e+00	632.00
IUUC-Gga-040903	Gallus gallus	74.50	1.00e-178	618.00
IUUC-Ggo-044635	Gorilla gorilla	91.65	0.00e+00	722.00
IUUC-Hsa-046345	Homo sapiens	91.40	0.00e+00	721.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	89.76	0.00e+00	688.00
IUUC-Lch-050599	Latimeria chalumnae	62.09	6.00e-142	496.00
IUUC-Loc-052378	Lepisosteus oculatus	63.28	8.00e-117	413.00
IUUC-Laf-053332	Loxodonta africana	90.93	0.00e+00	709.00
IUUC-Mcc-054705	Macaca mulatta	91.63	0.00e+00	729.00
IUUC-Meu-056825	Macropus eugenii	83.82	0.00e+00	704.00
IUUC-Mga-059528	Meleagris gallopavo	74.51	0.00e+00	629.00
IUUC-Mmr-060688	Microcebus murinus	93.12	0.00e+00	717.00
IUUC-Mdo-061882	Monodelphis domestica	83.82	0.00e+00	712.00
IUUC-Mmu-064352	Mus musculus	88.21	0.00e+00	729.00
IUUC-Mpu-066712	Mustela putorius furo	94.72	0.00e+00	679.00
IUUC-Nle-069310	Nomascus leucogenys	91.65	0.00e+00	718.00
IUUC-Ont-071759	Oreochromis niloticus	59.34	9.00e-110	390.00
IUUC-Oan-073673	Ornithorhynchus anatinus	79.17	0.00e+00	674.00
IUUC-Ocu-074192	Oryctolagus cuniculus	91.40	0.00e+00	721.00
IUUC-Ola-087424	Oryzias latipes	59.34	1.00e-108	386.00
IUUC-Oga-088808	Otolemur garnettii	92.38	0.00e+00	722.00
IUUC-Oar-089553	Ovis aries	92.38	0.00e+00	716.00
IUUC-Ptr-090518	Pan troglodytes	91.15	0.00e+00	718.00
IUUC-Pan-092781	Papio anubis	91.38	0.00e+00	726.00
IUUC-Psi-093914	Pelodiscus sinensis	74.33	8.00e-180	622.00
IUUC-Pfo-096346	Poecilia formosa	47.80	1.00e-107	382.00
IUUC-Pca-100914	Procavia capensis	87.99	0.00e+00	716.00
IUUC-Pva-102728	Pteropus vampyrus	95.58	0.00e+00	733.00
IUUC-Rno-105922	Rattus norvegicus	87.71	0.00e+00	668.00
IUUC-Sha-107124	Sarcophilus harrisii	83.82	0.00e+00	716.00
IUUC-Sar-113607	Sorex araneus	88.21	0.00e+00	682.00
IUUC-Ssc-116355	Sus scrofa	93.86	0.00e+00	724.00
IUUC-Tgu-116476	Taeniopygia guttata	75.25	0.00e+00	628.00
IUUC-Tru-118737	Takifugu rubripes	59.67	1.00e-111	395.00
IUUC-Tsy-118908	Tarsius syrichta	92.38	0.00e+00	738.00
IUUC-Tbe-127258	Tupaia belangeri	95.09	0.00e+00	732.00
IUUC-Vpa-130138	Vicugna pacos	92.38	0.00e+00	721.00
IUUC-Xtr-132100	Xenopus tropicalis	58.29	1.00e-132	466.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence