iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116814

Ensembl Protein ID

ENSTGUP00000012565.1

UniProt Accession

H0ZPN3; H0ZPN3_TAEGU

Genbank Protein ID

ENSTGUP00000012565

Protein Name

Autophagy protein 5

Genbank Nucleotide ID

ABQF01000469

Gene Name

ATG5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000012200.1	ENSTGUT00000012704.1	ENSTGUP00000012565.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	22.97	2.00e-11	64.30	IUUC-Sce-106216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Functional Description
(View)

Involved in autophagic vesicle formation.

Protein Sequence
(Fasta)

MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RISYLTLVTD KVKKHFQKVM 60
RQEEVSEIWF EYEGTPLKWH YPIGLLFDLH ASNTALPWSI TVHFKNFPEK DLLHCHSKDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGATG ACAAAGATGT ACTTCGAGAT GTGTGGTTTG GGCGAATACC GACCTGTTTC 60
ACTCTGTATC AGGATGAGAT AACTGAAAGG GAAGCTGAAC CCTACTATGT GAGTATGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0001974--P:blood vessel remodeling
GO:0019725--P:cellular homeostasis
GO:0071500--P:cellular response to nitrosative stress
GO:0009267--P:cellular response to starvation
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

KEGG

tgu:100227318

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000583	Aegilops tauschii	32.16	7.00e-23	102.00
IUUC-Aml-002403	Ailuropoda melanoleuca	88.45	5.00e-147	512.00
IUUC-Atr-002645	Amborella trichopoda	25.82	2.00e-21	95.90
IUUC-Apl-003611	Anas platyrhynchos	97.82	9.00e-164	568.00
IUUC-Aca-004411	Anolis carolinensis	90.29	5.00e-151	526.00
IUUC-Aly-005636	Arabidopsis lyrata	26.36	1.00e-25	109.00
IUUC-Ath-006959	Arabidopsis thaliana	26.67	1.00e-25	109.00
IUUC-Ago-007978	Ashbya gossypii	26.19	2.00e-06	45.80
IUUC-Acl-008328	Aspergillus clavatus	25.00	5.00e-21	94.40
IUUC-Afl-008638	Aspergillus flavus	25.56	2.00e-27	115.00
IUUC-Afu-009042	Aspergillus fumigatus	27.80	3.00e-30	124.00
IUUC-Ani-009364	Aspergillus nidulans	30.05	2.00e-24	105.00
IUUC-Aor-009889	Aspergillus oryzae	25.56	2.00e-27	115.00
IUUC-Ate-010511	Aspergillus terreus	34.41	8.00e-11	58.20
IUUC-Ame-011644	Astyanax mexicanus	84.81	2.00e-37	145.00
IUUC-Bgr-012153	Blumeria graminis	28.15	9.00e-18	83.60
IUUC-Bta-012360	Bos taurus	93.08	2.00e-84	303.00
IUUC-Bci-013723	Botrytis cinerea	24.91	2.00e-15	75.90
IUUC-Bdi-014520	Brachypodium distachyon	20.67	4.00e-19	88.20
IUUC-Bol-016053	Brassica oleracea	25.97	5.00e-28	117.00
IUUC-Bra-017072	Brassica rapa	26.65	2.00e-28	119.00
IUUC-Cel-018529	Caenorhabditis elegans	34.80	3.00e-37	147.00
IUUC-Cja-019569	Callithrix jacchus	89.45	6.00e-149	519.00
IUUC-Cfa-020473	Canis familiaris	89.82	4.00e-149	520.00
IUUC-Cpo-021421	Cavia porcellus	88.00	1.00e-146	511.00
IUUC-Cre-022862	Chlamydomonas reinhardtii	30.52	4.00e-17	80.90
IUUC-Csa-024197	Chlorocebus sabaeus	89.45	7.00e-149	518.00
IUUC-Cho-024521	Choloepus hoffmanni	86.19	3.00e-122	430.00
IUUC-Cin-025119	Ciona intestinalis	45.28	7.00e-66	243.00
IUUC-Csv-026192	Ciona savignyi	45.52	2.00e-66	244.00
IUUC-Cgl-026686	Colletotrichum gloeosporioides	23.36	4.00e-10	58.20
IUUC-Dre-028466	Danio rerio	80.00	3.00e-134	470.00
IUUC-Dse-031228	Dothistroma septosporum	27.12	3.00e-31	128.00
IUUC-Dme-031703	Drosophila melanogaster	47.97	2.00e-73	268.00
IUUC-Ete-032482	Echinops telfairi	85.77	7.00e-123	432.00
IUUC-Eca-034036	Equus caballus	88.73	2.00e-148	517.00
IUUC-Eeu-035235	Erinaceus europaeus	91.19	4.00e-83	300.00
IUUC-Fca-036263	Felis catus	89.82	2.00e-149	521.00
IUUC-Fal-037064	Ficedula albicollis	99.27	1.00e-164	571.00
IUUC-Fox-037813	Fusarium oxysporum	25.44	1.00e-16	79.30
IUUC-Fso-038139	Fusarium solani	25.61	1.00e-17	82.80
IUUC-Gmo-039509	Gadus morhua	82.43	1.00e-112	397.00
IUUC-Ggr-040111	Gaeumannomyces graminis	24.61	1.00e-13	69.70
IUUC-Gga-040517	Gallus gallus	97.82	4.00e-163	566.00
IUUC-Gac-042270	Gasterosteus aculeatus	72.00	7.00e-116	409.00
IUUC-Gma-044400	Glycine max	36.14	8.00e-23	100.00
IUUC-Ggo-045048	Gorilla gorilla	89.09	3.00e-147	513.00
IUUC-Hsa-046744	Homo sapiens	89.82	1.00e-148	518.00
IUUC-Kpa-049174	Komagataella pastoris	23.00	1.00e-13	70.10
IUUC-Lch-049475	Latimeria chalumnae	86.91	9.00e-147	511.00
IUUC-Lpe-051283	Leersia perrieri	32.62	3.00e-21	97.10
IUUC-Loc-052446	Lepisosteus oculatus	82.55	3.00e-141	493.00
IUUC-Lma-053278	Leptosphaeria maculans	27.19	1.00e-31	129.00
IUUC-Laf-054020	Loxodonta africana	88.45	4.00e-147	513.00
IUUC-Mcc-055176	Macaca mulatta	89.82	1.00e-148	518.00
IUUC-Mor-057164	Magnaporthe oryzae	25.00	7.00e-17	80.90
IUUC-Mpo-057428	Magnaporthe poae	26.73	4.00e-14	71.20
IUUC-Mtr-058424	Medicago truncatula	35.09	2.00e-22	99.00
IUUC-Mla-058872	Melampsora laricipopulina	29.41	4.00e-31	128.00
IUUC-Mga-059859	Meleagris gallopavo	97.82	4.00e-163	566.00
IUUC-Mmr-061482	Microcebus murinus	90.18	2.00e-149	520.00
IUUC-Mdo-062371	Monodelphis domestica	91.27	5.00e-154	536.00
IUUC-Mmu-063139	Mus musculus	88.73	4.00e-149	520.00
IUUC-Mac-065332	Musa acuminata	32.28	2.00e-24	105.00
IUUC-Mpu-066783	Mustela putorius furo	89.09	3.00e-148	516.00
IUUC-Mlu-068165	Myotis lucifugus	88.09	3.00e-145	506.00
IUUC-Nfi-068578	Neosartorya fischeri	27.16	5.00e-30	124.00
IUUC-Ncr-068636	Neurospora crassa	24.23	3.00e-12	65.90
IUUC-Nle-069740	Nomascus leucogenys	89.45	1.00e-148	518.00
IUUC-Opr-070802	Ochotona princeps	91.82	3.00e-82	297.00
IUUC-Ont-072222	Oreochromis niloticus	80.07	2.00e-135	474.00
IUUC-Oan-072760	Ornithorhynchus anatinus	90.86	2.00e-108	384.00
IUUC-Ocu-074844	Oryctolagus cuniculus	86.05	1.00e-89	321.00
IUUC-Oba-075834	Oryza barthii	31.07	2.00e-22	99.40
IUUC-Obr-076230	Oryza brachyantha	28.85	3.00e-12	65.50
IUUC-Ogl-077554	Oryza glaberrima	31.07	3.00e-22	99.00
IUUC-Ogu-078687	Oryza glumaepatula	30.62	1.00e-22	100.00
IUUC-Oin-079677	Oryza indica	24.63	3.00e-23	102.00
IUUC-Olo-081078	Oryza longistaminata	33.33	1.00e-22	100.00
IUUC-Ome-081548	Oryza meridionalis	32.18	9.00e-25	108.00
IUUC-Oni-082050	Oryza nivara	31.64	5.00e-23	101.00
IUUC-Opu-083609	Oryza punctata	31.46	5.00e-23	101.00
IUUC-Oru-085057	Oryza rufipogon	31.64	8.00e-23	100.00
IUUC-Osa-085917	Oryza sativa	31.64	9.00e-23	100.00
IUUC-Ola-087032	Oryzias latipes	78.99	8.00e-133	465.00
IUUC-Oga-088468	Otolemur garnettii	88.81	2.00e-150	523.00
IUUC-Oar-089751	Ovis aries	89.45	4.00e-149	519.00
IUUC-Ptr-091064	Pan troglodytes	89.82	1.00e-148	518.00
IUUC-Pan-092505	Papio anubis	88.81	5.00e-147	512.00
IUUC-Psi-093086	Pelodiscus sinensis	91.67	3.00e-155	540.00
IUUC-Pno-094825	Phaeosphaeria nodorum	27.40	8.00e-28	117.00
IUUC-Ppa-095419	Physcomitrella patens	31.93	6.00e-24	104.00
IUUC-Pfo-096224	Poecilia formosa	78.26	3.00e-132	463.00
IUUC-Pab-098501	Pongo abelii	89.09	1.00e-147	514.00
IUUC-Pop-099243	Populus trichocarpa	26.44	8.00e-24	103.00
IUUC-Ppe-101255	Prunus persica	25.79	1.00e-26	113.00
IUUC-Pva-102828	Pteropus vampyrus	88.73	2.00e-147	514.00
IUUC-Pgr-103672	Puccinia graminis	28.38	9.00e-27	114.00
IUUC-Ptt-104013	Puccinia triticina	26.52	2.00e-23	102.00
IUUC-Pyt-104615	Pyrenophora triticirepentis	28.34	6.00e-31	127.00
IUUC-Rno-106089	Rattus norvegicus	84.90	1.00e-126	444.00
IUUC-Sce-106216	Saccharomyces cerevisiae	22.97	6.00e-12	64.30
IUUC-Sha-106484	Sarcophilus harrisii	90.18	8.00e-153	531.00
IUUC-Sja-107699	Schizosaccharomyces japonicus	28.36	6.00e-28	117.00
IUUC-Spo-108177	Schizosaccharomyces pombe	27.71	2.00e-22	98.60
IUUC-Ssl-108475	Sclerotinia sclerotiorum	25.95	2.00e-16	79.00
IUUC-Smo-109473	Selaginella moellendorffii	25.38	5.00e-21	94.40
IUUC-Sit-110736	Setaria italica	33.16	3.00e-27	115.00
IUUC-Sly-111657	Solanum lycopersicum	35.98	8.00e-26	110.00
IUUC-Sar-113050	Sorex araneus	74.06	8.00e-100	355.00
IUUC-Sbi-114258	Sorghum bicolor	31.50	4.00e-25	108.00
IUUC-Sre-114902	Sporisorium reilianum	31.19	4.00e-24	105.00
IUUC-Ssc-116166	Sus scrofa	85.09	1.00e-141	494.00
IUUC-Tru-118172	Takifugu rubripes	78.99	5.00e-133	466.00
IUUC-Tsy-119010	Tarsius syrichta	77.82	2.00e-126	444.00
IUUC-Tni-120397	Tetraodon nigroviridis	82.41	4.00e-101	359.00
IUUC-Tca-121283	Theobroma cacao	32.47	6.00e-24	104.00
IUUC-Tvi-122545	Trichoderma virens	22.68	9.00e-14	70.10
IUUC-Tae-122685	Triticum aestivum	31.58	3.00e-23	101.00
IUUC-Tur-126407	Triticum urartu	32.89	7.00e-23	100.00
IUUC-Tme-126913	Tuber melanosporum	31.58	2.00e-40	158.00
IUUC-Tbe-127738	Tupaia belangeri	80.10	3.00e-95	340.00
IUUC-Ttr-128528	Tursiops truncatus	89.45	1.00e-148	518.00
IUUC-Uma-129625	Ustilago maydis	28.57	1.00e-22	100.00
IUUC-Vda-129906	Verticillium dahliae	22.31	9.00e-11	60.10
IUUC-Vpa-130223	Vicugna pacos	88.36	6.00e-143	499.00
IUUC-Vvi-131617	Vitis vinifera	34.76	7.00e-24	104.00
IUUC-Xtr-132288	Xenopus tropicalis	86.91	3.00e-147	513.00
IUUC-Xma-134214	Xiphophorus maculatus	83.42	4.00e-99	353.00
IUUC-Yli-134377	Yarrowia lipolytica	22.39	1.00e-09	56.20
IUUC-Zma-135108	Zea mays	34.03	2.00e-22	99.40

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence