iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000005724.1	ENSLOCT00000006915.1	ENSLOCP00000006907.1
ENSLOCG00000005724.1	ENSLOCT00000006935.1	ENSLOCP00000006927.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-81	272.6	448	891

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++ +   ++++         +l+ +lq+lf+ l +s++ a+sp ++l a  ++   f+   q
   Q: 448  TGLVNLGNTCYMNSVIQALFMASDFRRAVMS--LKNCDL-------LPLMGNLQRLFAFLEHSQRPAISPDSFLVA--SIPAWFTPGTQ 525
           7******************************..555554.......59************************9854..5666799**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           qD++E+l++lld+l+ee k++++k++ ++                 ++n +li+++F+g++ ++i+cl+c+n+s ree  +dlsl++p 
   Q: 526  QDCSEYLKYLLDRLHEEEKRSHQKTRGSLA--------------GSEENGTLIKKMFGGKMVTRIRCLRCQNISRREEALTDLSLALPP 600
           ******************776666666664..............455899**************************************8 PP
   S: 179  keetkke.................................................................................. 185
            +++  e                                                                                  
   Q: 601  PDHSP-Ersfiispsppvvevigpsslspsktqsqtllspkrnkklekpeehgvrvvpvetigdidkavpldsneevdsksfshgtsge 688
           88654.358******************************************************************************** PP
   S: 186  .........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
                    s+ d+++ f ++e+l+genky+c++c ++q+aek +++++ P++Lil L Rfsf+  +++r+ki ++v++pl L++   +
   Q: 689  pisgseaslSVPDLINFFLSPEMLTGENKYHCQRCSSLQNAEKVVEVTEGPHYLILTLLRFSFDVVTMRRKKILDNVSIPLVLKIPIRV 777
           *************************************************************************************9877 PP
   S: 266  tspeekqke................kkkYeLiavvvHsG.slssGHYvayvkn......................ekgkWllfdDskVt 315
           ts++ +++e                + +Y+L +vvvHsG s++sGHY++y+++                       +++W+lf+D++V+
   Q: 778  TSKDPASAEagklypesstegsayvSMTYDLGSVVVHSGlSSESGHYYCYAREcdygnlekqsntgahissqqptAENQWFLFNDTRVS 866
           7756665557888888888889999***********************************9999999999988888999********** PP
   S: 316  evkeeevleetg....staYvlfYk 336
            ++ e+v + t     +taYv+fY+
   Q: 867  FSSFESVSNVTTyfpkDTAYVMFYR 891
           *********999************8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MNMDKILEAV MMSPHSRAVK EGMVRRVIGS APQPLDRAQC MAMFDVATKL FLLGESQFKQ 60
DVGREVLEAF AQHHQQDFEE FFNVRFILDL LQEGYASLGK RSPQIFDYLQ VGLRYIIESP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAATACAGTA GTGGTGTCAC GGTGTTATTA TGTCACTTGC GAAGCGCACC AGAAAGAACG 60
AGGCGGCAGA GGAGAAGTGA GAAAGAGACG GGGAGTGGGG AGGAGAGCCT GGAGCGAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004121	Anas platyrhynchos	59.80	0.00e+00	1046.00
IUUC-Aca-005070	Anolis carolinensis	55.95	0.00e+00	720.00
IUUC-Csa-023167	Chlorocebus sabaeus	56.50	0.00e+00	664.00
IUUC-Csv-026333	Ciona savignyi	45.24	1.00e-34	139.00
IUUC-Dor-030538	Dipodomys ordii	57.46	1.00e-168	587.00
IUUC-Fal-037625	Ficedula albicollis	58.89	0.00e+00	1068.00
IUUC-Gga-040767	Gallus gallus	60.12	0.00e+00	1097.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	51.85	0.00e+00	857.00
IUUC-Lch-049513	Latimeria chalumnae	56.03	0.00e+00	1015.00
IUUC-Laf-053999	Loxodonta africana	52.01	0.00e+00	862.00
IUUC-Meu-056906	Macropus eugenii	59.04	0.00e+00	780.00
IUUC-Mga-059595	Meleagris gallopavo	58.92	0.00e+00	1068.00
IUUC-Mdo-062167	Monodelphis domestica	57.11	0.00e+00	1018.00
IUUC-Opr-070454	Ochotona princeps	49.86	1.00e-78	288.00
IUUC-Oga-088593	Otolemur garnettii	51.53	0.00e+00	838.00
IUUC-Pan-092168	Papio anubis	56.84	0.00e+00	663.00
IUUC-Psi-093707	Pelodiscus sinensis	59.37	0.00e+00	1074.00
IUUC-Sha-106686	Sarcophilus harrisii	58.67	0.00e+00	769.00
IUUC-Tgu-117024	Taeniopygia guttata	58.87	0.00e+00	1080.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence