iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052326

Ensembl Protein ID

ENSLOCP00000020707.1

UniProt Accession

W5NJ98; W5NJ98_LEPOC

Genbank Protein ID

ENSLOCP00000020707

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01033797

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000016755.1	ENSLOCT00000020743.1	ENSLOCP00000020707.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-13	50.2	50	107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            + v++++d++++n+ +L ++kGd+++v+   ++ ++W+ +++  +g +G +P  +v++l+
   Q: 50   SNIVIAQHDFQPVNEHDLAFQKGDKLTVL---QEKGDWWLAKSLVSGNEGYIPRTYVARLD 107
           6899*************************...78899*********************996 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGCICSSRKP DKDTADHWGK ENGHIDNSFP LRGPLAPPND HRLGSPDHDS NIVIAQHDFQ 60
PVNEHDLAFQ KGDKLTVLQE KGDWWLAKSL VSGNEGYIPR TYVARLDTLE VERWFFKNLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATGAATGTT GCCTAAGCTC TCTATCAGAC AGATGTCATC AGGAAGCTAA AGCAACCGGC 60
TACAGAGAGT TGTGTGTGTG AGACTGAGGA AGAGAAAAAC ACAGAGAGCA CAGCTCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	72.23	0.00e+00	712.00
IUUC-Apl-003307	Anas platyrhynchos	75.23	0.00e+00	723.00
IUUC-Ame-010642	Astyanax mexicanus	75.05	0.00e+00	791.00
IUUC-Bta-012400	Bos taurus	73.50	0.00e+00	707.00
IUUC-Cfa-021056	Canis familiaris	71.58	0.00e+00	706.00
IUUC-Cpo-021779	Cavia porcellus	73.11	0.00e+00	714.00
IUUC-Csa-023557	Chlorocebus sabaeus	71.96	0.00e+00	711.00
IUUC-Dre-027517	Danio rerio	75.56	0.00e+00	799.00
IUUC-Eca-034218	Equus caballus	71.49	0.00e+00	704.00
IUUC-Eeu-035095	Erinaceus europaeus	50.99	2.00e-143	501.00
IUUC-Fca-036015	Felis catus	71.15	0.00e+00	700.00
IUUC-Fal-036946	Ficedula albicollis	74.55	0.00e+00	717.00
IUUC-Gmo-038861	Gadus morhua	75.28	0.00e+00	713.00
IUUC-Gga-040822	Gallus gallus	74.78	0.00e+00	728.00
IUUC-Gac-041860	Gasterosteus aculeatus	69.88	0.00e+00	722.00
IUUC-Hsa-046719	Homo sapiens	71.52	0.00e+00	703.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	74.16	0.00e+00	703.00
IUUC-Lch-050114	Latimeria chalumnae	75.84	0.00e+00	730.00
IUUC-Laf-053387	Loxodonta africana	70.72	0.00e+00	698.00
IUUC-Mcc-055026	Macaca mulatta	72.17	0.00e+00	713.00
IUUC-Mga-059427	Meleagris gallopavo	74.33	0.00e+00	716.00
IUUC-Mmr-061660	Microcebus murinus	73.48	0.00e+00	707.00
IUUC-Mdo-062318	Monodelphis domestica	65.81	0.00e+00	703.00
IUUC-Mmu-063325	Mus musculus	72.08	0.00e+00	711.00
IUUC-Mpu-066582	Mustela putorius furo	71.37	0.00e+00	707.00
IUUC-Nle-069624	Nomascus leucogenys	73.54	0.00e+00	707.00
IUUC-Ont-072266	Oreochromis niloticus	74.00	0.00e+00	776.00
IUUC-Ocu-073907	Oryctolagus cuniculus	72.73	0.00e+00	711.00
IUUC-Ola-086668	Oryzias latipes	76.91	0.00e+00	740.00
IUUC-Oga-088057	Otolemur garnettii	73.09	0.00e+00	701.00
IUUC-Pan-092173	Papio anubis	73.26	0.00e+00	707.00
IUUC-Psi-093895	Pelodiscus sinensis	74.72	0.00e+00	721.00
IUUC-Pfo-096608	Poecilia formosa	72.46	0.00e+00	764.00
IUUC-Pab-097598	Pongo abelii	73.87	0.00e+00	707.00
IUUC-Pva-102135	Pteropus vampyrus	71.80	0.00e+00	709.00
IUUC-Rno-104891	Rattus norvegicus	71.90	0.00e+00	710.00
IUUC-Sha-107192	Sarcophilus harrisii	73.39	0.00e+00	713.00
IUUC-Ssc-115696	Sus scrofa	67.59	0.00e+00	713.00
IUUC-Tgu-117056	Taeniopygia guttata	74.72	0.00e+00	717.00
IUUC-Tru-117621	Takifugu rubripes	69.28	0.00e+00	724.00
IUUC-Ttr-128457	Tursiops truncatus	67.66	0.00e+00	710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence