iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028169

Ensembl Protein ID

ENSDARP00000056641.3

UniProt Accession

Q6P135; TMUB1_DANRE

Genbank Protein ID

AAH65312.1

Protein Name

Transmembrane and ubiquitin-like domain-containing protein 1

Genbank Nucleotide ID

BC065312

Gene Name

tmub1; zgc:77146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000038787.3	ENSDART00000056642.3	ENSDARP00000056641.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	1.10e-09	38.9	149	218

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 1    vqvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllek 72
           +++++k l+++e t +vnp+dt++ +K+     +  +++q+rLiy+G++L +d +tLa+++l d+s++h+  +
   Q: 149  MVLRLKFLNDTERTAQVNPQDTIGYIKRTY---FAGQEHQVRLIYQGQLLqDDSQTLASLNLADNSVLHCHIS 218
           5677888889999999************44...455578***********9******************9865 PP

Organism

Danio rerio

Functional Description
(View)

May contribute to the regulation of translation during cell-cycle progression. May contribute to the regulation of cell proliferation (By similarity). The membrane form is involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. May be involved in centrosome assembly.

Protein Sequence
(Fasta)

MALIEGVGDE VTLLFGVVFL VLVLVLAWAS THTVEPPEHL LSPSPGASPS TETDSQEPLP 60
PGNTDSSPGG VRDEDDKSEP GTEAGAAGQS ADGSRAGGGD GGLLDDAGLG SDGLRHRESA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGAATTTT TTTTTAAACC GGAAGTCGCC GTTGTGGCAT CGTTCTCTCC TGCCAGTGAT 60
CAGGAAGCGC AGACGTTAAA CGGTGCGAAT CATGGACCAT CATACGATGT GAAATGTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF00240--ubiquitin

SMART

SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus

KEGG

dre:406589

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004375	Anolis carolinensis	44.37	2.00e-42	166.00
IUUC-Cel-018429	Caenorhabditis elegans	44.44	4.00e-13	70.10
IUUC-Cin-025480	Ciona intestinalis	29.24	1.00e-13	70.50
IUUC-Csv-025923	Ciona savignyi	27.95	6.00e-16	78.20
IUUC-Fal-037183	Ficedula albicollis	56.78	1.00e-14	72.00
IUUC-Gmo-038613	Gadus morhua	72.93	2.00e-72	265.00
IUUC-Gga-040627	Gallus gallus	69.18	4.00e-46	177.00
IUUC-Gac-041487	Gasterosteus aculeatus	56.46	3.00e-62	231.00
IUUC-Lch-049467	Latimeria chalumnae	56.51	1.00e-81	296.00
IUUC-Loc-051998	Lepisosteus oculatus	64.29	4.00e-87	314.00
IUUC-Mga-059568	Meleagris gallopavo	70.50	2.00e-46	178.00
IUUC-Opr-070539	Ochotona princeps	54.62	5.00e-24	103.00
IUUC-Ont-072413	Oreochromis niloticus	83.44	9.00e-60	223.00
IUUC-Ola-087411	Oryzias latipes	59.25	2.00e-68	251.00
IUUC-Pma-094352	Petromyzon marinus	55.19	7.00e-34	137.00
IUUC-Ssc-116410	Sus scrofa	41.45	5.00e-32	131.00
IUUC-Tgu-117495	Taeniopygia guttata	58.90	9.00e-27	112.00
IUUC-Tru-118609	Takifugu rubripes	81.21	3.00e-60	224.00
IUUC-Tni-120885	Tetraodon nigroviridis	81.33	2.00e-61	228.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence