iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Opu-083697

Ensembl Protein ID

OPUNC03G28840.1

UniProt Accession

A0A0E0KI53; A0A0E0KI53_ORYPU

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OPUNC03G28840	OPUNC03G28840.1	OPUNC03G28840.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.70e-39	131.1	50	86
UBD/Beta-Prp	2.00e-76	257.9	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhaTQPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********6449********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           t +++++++++ + f+p +++++++  +g ++ wd+++g+ll ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++t  c+ tl+gh d++
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGVVQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYI 96
           67889999************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......................... 166
           ++++f+ +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                         
   Q: 97   RTVQFHHECPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIsalrkksvspaddilrltqmntdlf 189
           *********************************.**************************************************7777777777 PP
   S: 167  ..ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
               + + + l+g h++ v++ sf+++ + +vsg++d++vk+w +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ 
   Q: 190  ggVDAVVKYVLEG-HDRGVNWASFHPTLPLIVSGADDRQVKIWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTG 282
           6444444444466.********************************777668****************************************** PP
   S: 257  lktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++t+ +++++++  ++ +++ n l++g  ds   ++kl++++p
   Q: 283  IQTFRREHDRFWILSA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ****************.6666655555.689999999988765 PP

Organism

Oryza punctata

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GVVQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHHECPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACCA AGTTCGAGAC GAAGAGCAAC CGGGTGAAGG GTCTGAGCTT CCACCCGCGG 60
CGGCCATGGA TCCTTGCCAG CCTCCACAGC GGGGTGGTCC AGATGTGGGA CTACCGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001758	Ailuropoda melanoleuca	54.38	0.00e+00	1344.00
IUUC-Apl-003385	Anas platyrhynchos	49.58	0.00e+00	1025.00
IUUC-Afu-008964	Aspergillus fumigatus	47.29	0.00e+00	1122.00
IUUC-Cja-019107	Callithrix jacchus	53.32	0.00e+00	1326.00
IUUC-Cfa-020675	Canis familiaris	54.05	0.00e+00	1316.00
IUUC-Csa-023523	Chlorocebus sabaeus	55.01	0.00e+00	1361.00
IUUC-Eca-033773	Equus caballus	54.04	0.00e+00	1313.00
IUUC-Eeu-034874	Erinaceus europaeus	41.92	0.00e+00	657.00
IUUC-Gac-041318	Gasterosteus aculeatus	53.52	0.00e+00	1328.00
IUUC-Gma-043894	Glycine max	77.46	0.00e+00	1974.00
IUUC-Ggo-045029	Gorilla gorilla	54.62	0.00e+00	1350.00
IUUC-Hsa-046078	Homo sapiens	54.54	0.00e+00	1349.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	46.43	0.00e+00	747.00
IUUC-Kpa-049256	Komagataella pastoris	44.81	0.00e+00	1058.00
IUUC-Mcc-055836	Macaca mulatta	54.55	0.00e+00	1347.00
IUUC-Meu-056238	Macropus eugenii	57.10	0.00e+00	778.00
IUUC-Mtr-058248	Medicago truncatula	77.13	0.00e+00	1964.00
IUUC-Mdo-062594	Monodelphis domestica	55.02	0.00e+00	1379.00
IUUC-Mpu-066701	Mustela putorius furo	54.41	0.00e+00	1343.00
IUUC-Nfi-068270	Neosartorya fischeri	54.93	0.00e+00	966.00
IUUC-Opr-070952	Ochotona princeps	42.21	0.00e+00	651.00
IUUC-Ocu-074211	Oryctolagus cuniculus	54.85	0.00e+00	1350.00
IUUC-Oin-080029	Oryza indica	97.78	0.00e+00	2336.00
IUUC-Olo-080895	Oryza longistaminata	99.02	0.00e+00	1692.00
IUUC-Oga-087991	Otolemur garnettii	52.12	0.00e+00	1261.00
IUUC-Oar-089590	Ovis aries	54.77	0.00e+00	1353.00
IUUC-Ptr-090808	Pan troglodytes	54.62	0.00e+00	1351.00
IUUC-Psi-093044	Pelodiscus sinensis	54.13	0.00e+00	887.00
IUUC-Pfo-097493	Poecilia formosa	54.08	0.00e+00	1321.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	39.46	0.00e+00	724.00
IUUC-Sha-107301	Sarcophilus harrisii	53.97	0.00e+00	1335.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	46.42	0.00e+00	1111.00
IUUC-Sar-113313	Sorex araneus	41.98	0.00e+00	633.00
IUUC-Ssc-115933	Sus scrofa	54.93	0.00e+00	1353.00
IUUC-Tgu-117109	Taeniopygia guttata	44.44	1.00e-107	382.00
IUUC-Tru-117772	Takifugu rubripes	53.53	0.00e+00	1299.00
IUUC-Ttr-128217	Tursiops truncatus	52.59	0.00e+00	1282.00
IUUC-Xma-133138	Xiphophorus maculatus	54.08	0.00e+00	1322.00
IUUC-Yli-134399	Yarrowia lipolytica	49.25	0.00e+00	838.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence