iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tur-126016

Ensembl Protein ID

TRIUR3_10283-P1

UniProt Accession

M7YPQ2; M7YPQ2_TRIUA

Genbank Protein ID

EMS49387.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KD243776

Gene Name

TRIUR3_10283

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIUR3_10283	TRIUR3_10283-T1	TRIUR3_10283-P1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-30	102.2	47	83
UBD/Beta-Prp	3.10e-60	204.6	25	279

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH d ++ ++f ++ + +vs+sdD ti+vW++ + ++
   Q: 47   GHLDYIRTVQFhDEhPWIVSASDDQTIRVWNWQSRTC 83
           8**********866899**************988776 PP

UBD/Beta-Prp

   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrl 163
           +s+D+ ikvw+++t  c+ tl+gh d++++++f+ +  ++vs+s+d+tirvw++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+
   Q: 25   SSDDYKIKVWNYKTHRCLFTLHGHLDYIRTVQFHDEHPWIVSASDDQTIRVWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRV 117
           6889*********************************************************.******************************** PP
   S: 164  Wdl..........................ktgkllrtl.......tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnght 222
           Wd+                                           +gh++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh 
   Q: 118  WDIgalrkkssspaddimrltqmntdlfgG-------IdavvkyvLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHM 204
           ************999999666655555553.......04444445555********************************777668******** PP
   S: 223  dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +nv++v f+ +++++vs s+D+sir+Wd ++++ ++t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 205  NNVSCVLFHAKQDIIVSNSEDKSIRVWDATKRTGIQTFRREHDRFWVLAA-HPEMNLLAAG-HDSGMIVFKLERERP 279
           **************************************************.6666655555.689999999988765 PP

Organism

Triticum urartu

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MARPGWGTPW CLVGTGGPPP VGLCSSDDYK IKVWNYKTHR CLFTLHGHLD YIRTVQFHDE 60
HPWIVSASDD QTIRVWNWQS RTCVAVLTGH NHYVMCASFH PKEDLVVSAS LDQTVRVWDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACGCC CAGGGTGGGG CACGCCTTGG TGCCTTGTGG GCACAGGTGG TCCCCCTCCA 60
GTGGGTCTTT GCTCCAGTAT GTTTTATATA TTCCATAAAA AAATTCTAAA AAGTTTCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000201	Aegilops tauschii	99.31	0.00e+00	2319.00
IUUC-Apl-003385	Anas platyrhynchos	49.72	0.00e+00	1029.00
IUUC-Ame-011229	Astyanax mexicanus	51.62	0.00e+00	1182.00
IUUC-Bdi-014214	Brachypodium distachyon	94.38	0.00e+00	2226.00
IUUC-Cho-024704	Choloepus hoffmanni	42.41	6.00e-168	584.00
IUUC-Cme-027222	Cyanidioschyzon merolae	42.65	4.00e-146	512.00
IUUC-Dme-031945	Drosophila melanogaster	50.04	0.00e+00	1111.00
IUUC-Eeu-034874	Erinaceus europaeus	41.99	0.00e+00	654.00
IUUC-Hvu-047556	Hordeum vulgare	98.61	0.00e+00	2322.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	45.93	0.00e+00	752.00
IUUC-Mvi-060336	Microbotryum violaceum	49.49	0.00e+00	1092.00
IUUC-Opr-070952	Ochotona princeps	41.97	0.00e+00	648.00
IUUC-Sar-113313	Sorex araneus	41.98	0.00e+00	635.00
IUUC-Tgu-117109	Taeniopygia guttata	50.00	7.00e-103	366.00
IUUC-Tca-121545	Theobroma cacao	77.01	0.00e+00	1862.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence