iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000003581.3	ENSCAFT00000046528.1	ENSCAFP00000041316.1
ENSCAFG00000003581.3	ENSCAFT00000005752.3	ENSCAFP00000005324.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.80e-08	34.7	98	149

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek.slveCekCrewfHpaClkls.veeelpnsekwiCpkCr 52
            C +C  ++++   +++ C kC   +H++C+ +   + ++p  ++w+C++C 
   Q: 98   KCNICLGKTSGPLnEILICGKCGLGYHQQCHIPRaGSADRPLLTPWFCRRCI 149
           5999*99888764589*****************977778888888******6 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MENHTLDPGT RDSYGATSHL PNKGALAKAK NNFKDLMSKL TEGQYVLCRW TDGLYYLGKI 60
KRVSSSKQSC LVTFEDNSKY WVLWKDIQHA GVPGEEPKCN ICLGKTSGPL NEILICGKCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAATC ACACTCTGGA CCCAGGGACT CGGGACTCCT ATGGTGCCAC CAGCCACCTC 60
CCCAACAAGG GGGCCCTGGC AAAAGCCAAG AACAACTTCA AAGACCTGAT GTCCAAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025894--Mtf2_C_dom
IPR002999--Tudor
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1

Pfam

PF14061--Mtf2_C
PF00628--PHD

SMART

SM00249--PHD
SM00333--TUDOR

Gene Ontology

GO:0035098--C:ESC/E(Z) complex
GO:0008270--F:zinc ion binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0061087--P:positive regulation of histone H3-K27 methylation
GO:0048863--P:stem cell differentiation
GO:0019827--P:stem cell population maintenance

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002293	Ailuropoda melanoleuca	77.87	0.00e+00	793.00
IUUC-Apl-003282	Anas platyrhynchos	58.91	3.00e-116	412.00
IUUC-Cme-027282	Cyanidioschyzon merolae	48.39	2.50e-01	29.30
IUUC-Dre-028079	Danio rerio	53.08	7.00e-153	533.00
IUUC-Ete-032758	Echinops telfairi	69.31	0.00e+00	651.00
IUUC-Gmo-039321	Gadus morhua	46.70	1.00e-114	407.00
IUUC-Gac-042130	Gasterosteus aculeatus	46.22	5.00e-113	401.00
IUUC-Itr-048903	Ictidomys tridecemlineatus	71.27	5.00e-170	590.00
IUUC-Lch-050049	Latimeria chalumnae	60.79	1.00e-167	582.00
IUUC-Loc-052034	Lepisosteus oculatus	56.57	3.00e-155	541.00
IUUC-Mga-059421	Meleagris gallopavo	63.59	2.00e-169	589.00
IUUC-Mdo-062362	Monodelphis domestica	67.69	0.00e+00	696.00
IUUC-Mpu-065837	Mustela putorius furo	77.93	0.00e+00	800.00
IUUC-Oan-073043	Ornithorhynchus anatinus	73.33	2.00e-98	352.00
IUUC-Oga-089023	Otolemur garnettii	77.41	0.00e+00	795.00
IUUC-Pva-103007	Pteropus vampyrus	75.10	0.00e+00	647.00
IUUC-Ssc-116063	Sus scrofa	68.35	7.00e-121	426.00
IUUC-Tni-120027	Tetraodon nigroviridis	45.07	1.00e-114	407.00
IUUC-Ttr-128678	Tursiops truncatus	70.60	0.00e+00	665.00
IUUC-Vpa-130085	Vicugna pacos	72.79	1.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence