iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011861

Ensembl Protein ID

ENSAMXP00000022180.1

UniProt Accession

W5LQ83; W5LQ83_ASTMX

Genbank Protein ID

ENSAMXP00000022180

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01103256

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000021535.1	ENSAMXT00000022180.1	ENSAMXP00000022180.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	6.70e-226	752.0	19	657

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk............................vgaklYkklkevleefikqvkkkveese 61
           lr++++++++++s+ k++y+elyt+vyn+c+s                             vg +lYk+lke+l+++++++ k+ e+ +
   Q: 19   LRAGIQQVYTRQSMaKSRYMELYTHVYNYCTSVhqsnqtrgagvppakpskksptpggaqfVGLELYKRLKEFLKNYLTNLLKDGEDLM 107
           7899***************************9999****************************************************** PP
   S: 62   deqlLktynreWekfreqlkvlrkifayldrtyvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrl 145
           de++Lk+y+++We++r ++kvl+ i+ayl+r++v++     +k ++e+++Lal +wr++++++++k++++++lklie+eR+ge++++rl
   Q: 108  DESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRecdegRKGIYEIYSLALVTWRECLFRPLNKQVTNAVLKLIERERNGETINTRL 196
           ************************************999999999******************************************** PP
   S: 146  lsgvveslveLslnk.........laiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLle 225
           +sgvv+s+veL+ln+         l++yke FE +fl  t++fy++es+eflq+n v+eY+kk+earl ee++r++ yl+est+++L++
   Q: 197  ISGVVQSYVELGLNEddafakgptLSVYKEYFETQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELAR 285
           ***************************************************************************************** PP
   S: 226  vvekeliakhlesllaelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklq 312
           ++e++li+khle +++e+++ll+ +k+edl+rmy+L+sr+++gl el k le+hi++qg+aa++     + +dpk+yV+++l++++k++
   Q: 286  KCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRITDGLGELKKLLETHIHNQGLAAIEkcGDSALNDPKMYVQTILDVHKKYN 374
           ****************************************************************8888999****************** PP
   S: 313  klvseaFnndakFlkaldkafetfvnknsvlka....akspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYk 397
            lv++aFnnda F+ aldka+ +f+n+n+v+k+    +kspEllAry+D+lL+kssk+++e+ele++l++v++vfkyi++kdvF+k+Y+
   Q: 375  ALVMSAFNNDAGFVAALDKACGRFINNNAVTKMaqssSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYA 463
           ***************************************************************************************** PP
   S: 398  khLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvs 486
           k+LakRL++++sas++aE+s+i+kLk++cg+e+tskL+rMfqd+ vS+dln+qFk++ +n+ e  ++++s++vLs+g+Wp++++   ++
   Q: 464  KMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLSNS-EPLDLDFSIQVLSSGSWPFQQSCT-FA 550
           *******************************************************888776.99******************7755.** PP
   S: 487  LPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsL 575
           LP+ele+++++f++fY ++hsgRkL+W+++l+++el ++++k++y+lq+stfQma+LL+fn++++++v++l+++++++ + L ++lq L
   Q: 551  LPSELERSYQRFTAFYASRHSGRKLTWLYHLSKGELVTNCFKNRYTLQASTFQMAILLQFNTENSYTVQQLADSSQIKIDILVQVLQIL 639
           ***************************************************************************************** PP
   S: 576  vsskkqvlkkepeskeieee 595
           ++sk  +l  e+e+++i+e 
   Q: 640  LKSK--LLVLEDENANIDEM 657
           ***9..77777777777664 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MSNPHGLKQI GLDQIWDDLR AGIQQVYTRQ SMAKSRYMEL YTHVYNYCTS VHQSNQTRGA 60
GVPPAKPSKK SPTPGGAQFV GLELYKRLKE FLKNYLTNLL KDGEDLMDES VLKFYTQQWE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCAGAAAGG AGGGATTCAT CTGACAAAAA GGAGGAGAGC AGACAGACGA TGTCGAACCC 60
CCACGGACTC AAACAGATCG GGCTGGACCA GATTTGGGAT GACCTGCGAG CGGGCATTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002277	Ailuropoda melanoleuca	95.85	0.00e+00	1510.00
IUUC-Apl-003503	Anas platyrhynchos	96.68	0.00e+00	1228.00
IUUC-Aca-005030	Anolis carolinensis	83.99	0.00e+00	1172.00
IUUC-Ago-007977	Ashbya gossypii	32.10	3.00e-116	412.00
IUUC-Acl-008190	Aspergillus clavatus	48.51	0.00e+00	662.00
IUUC-Afl-008542	Aspergillus flavus	49.27	4.00e-155	541.00
IUUC-Afu-009007	Aspergillus fumigatus	48.56	0.00e+00	644.00
IUUC-Ani-009290	Aspergillus nidulans	46.81	0.00e+00	684.00
IUUC-Ang-009600	Aspergillus niger	48.53	0.00e+00	664.00
IUUC-Aor-009978	Aspergillus oryzae	49.63	3.00e-172	598.00
IUUC-Ate-010584	Aspergillus terreus	47.63	0.00e+00	674.00
IUUC-Bgr-012209	Blumeria graminis	48.02	0.00e+00	654.00
IUUC-Bta-012878	Bos taurus	95.97	0.00e+00	1515.00
IUUC-Bci-013941	Botrytis cinerea	48.01	0.00e+00	712.00
IUUC-Cel-018294	Caenorhabditis elegans	46.61	0.00e+00	695.00
IUUC-Cja-018965	Callithrix jacchus	91.83	0.00e+00	1439.00
IUUC-Cfa-020671	Canis familiaris	95.97	0.00e+00	1515.00
IUUC-Cpo-021762	Cavia porcellus	95.97	0.00e+00	1515.00
IUUC-Csa-023873	Chlorocebus sabaeus	96.10	0.00e+00	1517.00
IUUC-Cho-024978	Choloepus hoffmanni	96.00	1.00e-112	400.00
IUUC-Cin-025547	Ciona intestinalis	72.97	0.00e+00	1121.00
IUUC-Csv-026083	Ciona savignyi	72.40	0.00e+00	1166.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	48.83	0.00e+00	681.00
IUUC-Cne-026919	Cryptococcus neoformans	42.98	0.00e+00	631.00
IUUC-Dre-027875	Danio rerio	97.53	0.00e+00	1477.00
IUUC-Dno-028931	Dasypus novemcinctus	96.10	0.00e+00	1511.00
IUUC-Dor-030846	Dipodomys ordii	96.10	0.00e+00	987.00
IUUC-Dse-031472	Dothistroma septosporum	46.16	0.00e+00	627.00
IUUC-Dme-031793	Drosophila melanogaster	62.95	0.00e+00	948.00
IUUC-Ete-033112	Echinops telfairi	84.84	3.00e-161	561.00
IUUC-Eca-034309	Equus caballus	95.97	0.00e+00	1515.00
IUUC-Eeu-034450	Erinaceus europaeus	73.77	0.00e+00	629.00
IUUC-Fca-036330	Felis catus	92.52	0.00e+00	1452.00
IUUC-Fal-036899	Ficedula albicollis	95.82	0.00e+00	1319.00
IUUC-Fox-037705	Fusarium oxysporum	48.94	0.00e+00	658.00
IUUC-Fso-038367	Fusarium solani	49.36	0.00e+00	678.00
IUUC-Gmo-038708	Gadus morhua	93.93	0.00e+00	1456.00
IUUC-Ggr-039917	Gaeumannomyces graminis	47.24	0.00e+00	679.00
IUUC-Gga-041038	Gallus gallus	96.10	0.00e+00	1517.00
IUUC-Gac-041820	Gasterosteus aculeatus	95.99	0.00e+00	1516.00
IUUC-Ggo-045154	Gorilla gorilla	79.78	0.00e+00	1070.00
IUUC-Hsa-046034	Homo sapiens	96.10	0.00e+00	1517.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	95.97	0.00e+00	1515.00
IUUC-Kpa-049231	Komagataella pastoris	38.43	4.00e-132	465.00
IUUC-Lch-049673	Latimeria chalumnae	95.71	0.00e+00	1506.00
IUUC-Loc-052490	Lepisosteus oculatus	97.40	0.00e+00	1509.00
IUUC-Lma-053191	Leptosphaeria maculans	48.84	0.00e+00	670.00
IUUC-Laf-054582	Loxodonta africana	95.84	0.00e+00	1514.00
IUUC-Mcc-055162	Macaca mulatta	95.19	0.00e+00	1497.00
IUUC-Meu-055904	Macropus eugenii	83.67	2.00e-153	536.00
IUUC-Mor-057035	Magnaporthe oryzae	46.92	0.00e+00	647.00
IUUC-Mpo-057555	Magnaporthe poae	47.24	0.00e+00	679.00
IUUC-Mla-059021	Melampsora laricipopulina	47.87	0.00e+00	660.00
IUUC-Mga-060078	Meleagris gallopavo	96.10	0.00e+00	1517.00
IUUC-Mvi-060519	Microbotryum violaceum	47.29	0.00e+00	677.00
IUUC-Mmr-061312	Microcebus murinus	96.10	0.00e+00	1517.00
IUUC-Mdo-062867	Monodelphis domestica	95.84	0.00e+00	1511.00
IUUC-Mmu-063336	Mus musculus	96.10	0.00e+00	1517.00
IUUC-Mpu-066400	Mustela putorius furo	95.67	0.00e+00	1317.00
IUUC-Mlu-067800	Myotis lucifugus	95.98	0.00e+00	1511.00
IUUC-Nfi-068384	Neosartorya fischeri	50.73	0.00e+00	647.00
IUUC-Ncr-068965	Neurospora crassa	48.45	0.00e+00	680.00
IUUC-Nle-069729	Nomascus leucogenys	96.10	0.00e+00	1517.00
IUUC-Ont-071729	Oreochromis niloticus	95.58	0.00e+00	1488.00
IUUC-Oan-073309	Ornithorhynchus anatinus	96.23	0.00e+00	1519.00
IUUC-Ocu-074661	Oryctolagus cuniculus	95.06	0.00e+00	1472.00
IUUC-Ola-087422	Oryzias latipes	95.20	0.00e+00	1497.00
IUUC-Oga-088130	Otolemur garnettii	96.10	0.00e+00	1517.00
IUUC-Oar-089510	Ovis aries	94.41	0.00e+00	1446.00
IUUC-Ptr-090665	Pan troglodytes	96.10	0.00e+00	1517.00
IUUC-Pan-092218	Papio anubis	96.10	0.00e+00	1517.00
IUUC-Psi-093175	Pelodiscus sinensis	95.97	0.00e+00	1515.00
IUUC-Pma-094502	Petromyzon marinus	89.48	0.00e+00	1409.00
IUUC-Pno-095067	Phaeosphaeria nodorum	48.71	0.00e+00	696.00
IUUC-Pfo-096705	Poecilia formosa	95.84	0.00e+00	1530.00
IUUC-Pab-097578	Pongo abelii	96.10	0.00e+00	1517.00
IUUC-Pca-100242	Procavia capensis	91.24	0.00e+00	1051.00
IUUC-Pva-102155	Pteropus vampyrus	84.55	0.00e+00	1295.00
IUUC-Pgr-103297	Puccinia graminis	46.25	0.00e+00	669.00
IUUC-Ptt-103706	Puccinia triticina	45.54	1.00e-93	338.00
IUUC-Pte-104257	Pyrenophora teres	48.84	0.00e+00	695.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	48.91	0.00e+00	695.00
IUUC-Rno-105939	Rattus norvegicus	96.10	0.00e+00	1517.00
IUUC-Sce-106293	Saccharomyces cerevisiae	31.52	4.00e-113	402.00
IUUC-Sha-106949	Sarcophilus harrisii	96.23	0.00e+00	1518.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	42.34	2.00e-157	549.00
IUUC-Spo-108280	Schizosaccharomyces pombe	41.06	2.00e-164	573.00
IUUC-Sre-114984	Sporisorium reilianum	45.40	5.00e-180	624.00
IUUC-Ssc-115829	Sus scrofa	95.34	0.00e+00	1497.00
IUUC-Tgu-116950	Taeniopygia guttata	96.10	0.00e+00	1517.00
IUUC-Tru-118558	Takifugu rubripes	95.06	0.00e+00	1503.00
IUUC-Tsy-118934	Tarsius syrichta	94.65	0.00e+00	701.00
IUUC-Tni-120460	Tetraodon nigroviridis	94.94	0.00e+00	1509.00
IUUC-Tre-122223	Trichoderma reesei	49.79	0.00e+00	644.00
IUUC-Tvi-122539	Trichoderma virens	44.66	1.00e-174	606.00
IUUC-Tme-126926	Tuber melanosporum	48.07	0.00e+00	685.00
IUUC-Tbe-127369	Tupaia belangeri	93.29	0.00e+00	627.00
IUUC-Ttr-129022	Tursiops truncatus	90.08	0.00e+00	1100.00
IUUC-Uma-129341	Ustilago maydis	45.97	9.00e-173	600.00
IUUC-Vda-129857	Verticillium dahliae	47.59	0.00e+00	649.00
IUUC-Vpa-130166	Vicugna pacos	90.11	0.00e+00	1173.00
IUUC-Xtr-131818	Xenopus tropicalis	95.71	0.00e+00	1501.00
IUUC-Xma-134206	Xiphophorus maculatus	97.01	0.00e+00	1489.00
IUUC-Yli-134486	Yarrowia lipolytica	39.49	9.00e-152	530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence