iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086716

UUCD1 version

UUC-OrL-01022

Ensembl Protein ID

ENSORLP00000025805.1

UniProt Accession

H2N2W5; H2N2W5_ORYLA

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Gene Name

wdr4; WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000020836.1	ENSORLT00000025805.1	ENSORLP00000025804.1
ENSORLG00000020836.1	ENSORLT00000025806.1	ENSORLP00000025805.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-08	33.4	185	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH   v++l+     + + l+sGs+Dgt+k+W++ +g++l+s
   Q: 185  GHRQFVSALHIpagrP-DWLLSGSGDGTVKLWEFESGRQLQS 225
           6888899999998766.779******************9986 PP

Organism

Oryzias latipes

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

RGNMRTLGFC GDWLVTSCGT KLVAVHTKED REAFVFDCSL AEKKPKQTKG DDTSEETGND 60
EVLAVATSAS GKLLALTDDT KRLVLFGCEP SWRCISTRWV VRRCTALTFS RAEDELLLAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTCGCGAG AACATCATGT TTGGAAAAGT AAAACATCGA CATAGAGGTT CGGCTTGTTA 60
GAATTTTCCC ACATAATCTG TTTGGTTCCG GAAAAACGAT GAAATGTTTC TGTATCTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	26.36	2.00e-08	53.50
IUUC-Atr-002431	Amborella trichopoda	30.46	3.00e-10	57.00
IUUC-Apl-003975	Anas platyrhynchos	40.46	5.00e-71	261.00
IUUC-Aca-005170	Anolis carolinensis	38.97	8.00e-62	230.00
IUUC-Aly-005769	Arabidopsis lyrata	30.71	4.00e-24	105.00
IUUC-Ath-006733	Arabidopsis thaliana	30.77	2.00e-24	107.00
IUUC-Acl-008151	Aspergillus clavatus	37.74	1.00e-14	74.30
IUUC-Afl-008518	Aspergillus flavus	31.94	9.00e-17	80.90
IUUC-Afu-009102	Aspergillus fumigatus	28.62	2.00e-16	80.50
IUUC-Ani-009442	Aspergillus nidulans	28.16	2.00e-16	80.50
IUUC-Aor-010133	Aspergillus oryzae	26.06	2.00e-17	83.60
IUUC-Ate-010465	Aspergillus terreus	26.21	4.00e-16	79.00
IUUC-Ame-010613	Astyanax mexicanus	52.65	8.00e-106	377.00
IUUC-Bgr-012067	Blumeria graminis	39.37	2.00e-18	86.70
IUUC-Bta-012788	Bos taurus	42.86	2.00e-75	275.00
IUUC-Bdi-014458	Brachypodium distachyon	34.38	6.00e-16	78.60
IUUC-Bol-016398	Brassica oleracea	36.00	7.00e-27	114.00
IUUC-Bra-016644	Brassica rapa	33.85	6.00e-26	113.00
IUUC-Cpo-021963	Cavia porcellus	42.16	3.00e-75	275.00
IUUC-Csa-024148	Chlorocebus sabaeus	43.68	3.00e-68	252.00
IUUC-Cne-026834	Cryptococcus neoformans	37.50	8.00e-25	108.00
IUUC-Dre-028427	Danio rerio	54.99	7.00e-118	417.00
IUUC-Dno-028881	Dasypus novemcinctus	37.91	1.00e-59	223.00
IUUC-Dor-030522	Dipodomys ordii	41.98	6.00e-74	271.00
IUUC-Dme-032136	Drosophila melanogaster	38.82	3.00e-22	99.40
IUUC-Fca-035833	Felis catus	43.30	1.00e-69	256.00
IUUC-Fal-037497	Ficedula albicollis	40.75	2.00e-74	272.00
IUUC-Gga-040547	Gallus gallus	40.68	1.00e-71	263.00
IUUC-Gac-041761	Gasterosteus aculeatus	55.15	7.00e-117	413.00
IUUC-Gma-043722	Glycine max	33.88	2.00e-22	100.00
IUUC-Ggo-045340	Gorilla gorilla	43.42	3.00e-70	258.00
IUUC-Hsa-046403	Homo sapiens	44.21	4.00e-72	265.00
IUUC-Hvu-047643	Hordeum vulgare	32.93	2.00e-18	86.70
IUUC-Itr-048103	Ictidomys tridecemlineatus	44.09	2.00e-78	286.00
IUUC-Kpa-049283	Komagataella pastoris	33.71	3.00e-19	89.40
IUUC-Lch-050682	Latimeria chalumnae	40.60	3.00e-79	288.00
IUUC-Lpe-050712	Leersia perrieri	32.05	7.00e-22	98.20
IUUC-Loc-052599	Lepisosteus oculatus	51.01	3.00e-109	388.00
IUUC-Laf-054390	Loxodonta africana	43.04	1.00e-75	276.00
IUUC-Mcc-054747	Macaca mulatta	43.95	8.00e-70	257.00
IUUC-Mtr-058600	Medicago truncatula	36.70	7.00e-26	111.00
IUUC-Mla-059135	Melampsora laricipopulina	28.40	6.00e-15	75.50
IUUC-Mga-059876	Meleagris gallopavo	40.11	8.00e-72	263.00
IUUC-Mvi-060359	Microbotryum violaceum	31.90	3.00e-14	73.60
IUUC-Mmr-061518	Microcebus murinus	44.24	8.00e-75	273.00
IUUC-Mac-065625	Musa acuminata	36.23	4.00e-23	102.00
IUUC-Nfi-068402	Neosartorya fischeri	27.10	3.00e-16	79.70
IUUC-Nle-069914	Nomascus leucogenys	42.11	2.00e-63	236.00
IUUC-Ont-071555	Oreochromis niloticus	56.88	8.00e-124	436.00
IUUC-Oan-072951	Ornithorhynchus anatinus	42.78	1.00e-75	276.00
IUUC-Ocu-074679	Oryctolagus cuniculus	43.42	1.00e-69	256.00
IUUC-Oba-075355	Oryza barthii	25.82	1.00e-09	57.80
IUUC-Obr-076769	Oryza brachyantha	34.05	9.00e-23	101.00
IUUC-Ogl-077168	Oryza glaberrima	30.49	2.00e-22	100.00
IUUC-Ogu-078275	Oryza glumaepatula	31.78	2.00e-09	57.40
IUUC-Oin-079207	Oryza indica	30.49	2.00e-22	100.00
IUUC-Oni-082437	Oryza nivara	25.82	2.00e-09	57.00
IUUC-Opu-084031	Oryza punctata	31.30	1.00e-22	100.00
IUUC-Oru-084380	Oryza rufipogon	25.82	2.00e-09	57.00
IUUC-Osa-085327	Oryza sativa	30.49	3.00e-22	99.40
IUUC-Olu-087708	Ostreococcus lucimarinus	25.77	3.00e-16	79.30
IUUC-Oar-090239	Ovis aries	42.93	1.00e-76	279.00
IUUC-Ptr-090851	Pan troglodytes	43.68	8.00e-71	260.00
IUUC-Pan-092558	Papio anubis	42.78	7.00e-68	250.00
IUUC-Psi-093792	Pelodiscus sinensis	38.62	4.00e-73	268.00
IUUC-Ppa-095757	Physcomitrella patens	31.52	1.00e-23	103.00
IUUC-Pfo-096465	Poecilia formosa	57.83	3.00e-126	444.00
IUUC-Pab-097722	Pongo abelii	43.77	1.00e-72	266.00
IUUC-Pop-098979	Populus trichocarpa	31.56	2.00e-24	106.00
IUUC-Pca-100753	Procavia capensis	39.38	3.00e-44	172.00
IUUC-Ppe-101515	Prunus persica	32.34	2.00e-22	99.80
IUUC-Sja-107780	Schizosaccharomyces japonicus	27.56	4.00e-15	75.50
IUUC-Spo-108251	Schizosaccharomyces pombe	26.97	7.00e-16	78.20
IUUC-Smo-108938	Selaginella moellendorffii	32.32	3.00e-21	95.90
IUUC-Sit-110020	Setaria italica	30.00	4.00e-21	95.90
IUUC-Sly-111543	Solanum lycopersicum	35.08	2.00e-22	100.00
IUUC-Stu-111925	Solanum tuberosum	33.48	1.00e-22	100.00
IUUC-Sbi-114061	Sorghum bicolor	32.26	7.00e-22	98.20
IUUC-Tgu-117321	Taeniopygia guttata	40.62	7.00e-70	257.00
IUUC-Tru-118454	Takifugu rubripes	58.42	1.00e-115	409.00
IUUC-Tni-119894	Tetraodon nigroviridis	54.25	6.00e-99	353.00
IUUC-Tca-121746	Theobroma cacao	32.97	1.00e-25	110.00
IUUC-Tae-124459	Triticum aestivum	33.06	8.00e-19	88.20
IUUC-Tur-126254	Triticum urartu	28.95	4.00e-10	58.90
IUUC-Tbe-127683	Tupaia belangeri	31.46	2.00e-24	106.00
IUUC-Ttr-129056	Tursiops truncatus	41.69	4.00e-71	261.00
IUUC-Vvi-131428	Vitis vinifera	34.48	2.00e-23	103.00
IUUC-Xma-133605	Xiphophorus maculatus	57.58	2.00e-127	448.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence