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Tag Content
UUCD2 ID IUUC-Csv-025864
UUCD1 version UUC-CiS-00228
Ensembl Protein ID ENSCSAVP00000009686.1
UniProt Accession H2YWH5; H2YWH5_CIOSA
Protein Name Coatomer subunit alpha
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCSAVG00000005686.1 ENSCSAVT00000009804.1 ENSCSAVP00000009686.1
ENSCSAVG00000005686.1 ENSCSAVT00000009805.1 ENSCSAVP00000009687.1
ENSCSAVG00000005686.1 ENSCSAVT00000009806.1 ENSCSAVP00000009688.1
ENSCSAVG00000005686.1 ENSCSAVT00000009807.1 ENSCSAVP00000009689.1
ENSCSAVG00000005686.1 ENSCSAVT00000009808.1 ENSCSAVP00000009690.1
ENSCSAVG00000005686.1 ENSCSAVT00000009809.1 ENSCSAVP00000009691.1
ENSCSAVG00000005686.1 ENSCSAVT00000009810.1 ENSCSAVP00000009692.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.70e-31 105.8 50 80
UBD/Beta-Prp 3.00e-71 240.0 3 333
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++v++++f +  +l+vsG+dD +ik+W++
   Q: 50   HDGPVRGVCFhNQqPLFVSGGDDYKIKIWNY 80
           99********9667***************96 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           t +++++++++ + f+p++++++++  +g+i++wd+++ +l+ ++++h+++v+ v+f+++++++v+g++D+ ik+w+++ + c+ tl 
   Q: 3    TKFETKSARVKGLSFHPKRPWVLSSLHNGCIQLWDYRMCTLIDKFEEHDGPVRGVCFHNQQPLFVSGGDDYKIKIWNYKLRRCLFTLL 90
           67889999******************************************************************************** PP
   S: 92   ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............. 166
           gh d++++  f+ +  +++s+s+d+tir+w+++++ c+  +l+gh++ v+++++hp+++l+vs+slD+t r+Wd+             
   Q: 91   GHLDYIRTAVFHHEYPWILSASDDQTIRIWNWQSRNCIA-VLTGHNHYVMSAHFHPTEDLIVSASLDQTARVWDIsglrkknlspggs 177
           ***************************************.************************************************ PP
   S: 167  ........................ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksv 228
                                   +t++++++  +gh++ v++  f+++ + +v++++d+ vklw + +++   v++++gh +nv + 
   Q: 178  sieetirgtpgagsggpssielfgSTDFMVKHVLEGHDRGVNWACFHPSLPVVVTAADDRLVKLWRMNESKAweVDSCRGHYNNVACC 265
           ********************************9888********************************888878************** PP
   S: 229  rfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
            f+p++++++s+s+D+sir+Wd+ +++ ++++ +++ +++   + +++ n +++g  d+   i+kl++++p
   Q: 266  VFHPRQDLIISASEDKSIRVWDMGKRTSINSFRREE-RFWILGC-HPSLNLFAAGH-DNGMVIFKLERERP 333
           *********************************965.*******.78877777664.67899999988765 PP
   
Organism Ciona savignyi
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
Protein Sequence
(Fasta)
MLTKFETKSA RVKGLSFHPK RPWVLSSLHN GCIQLWDYRM CTLIDKFEEH DGPVRGVCFH 60
NQQPLFVSGG DDYKIKIWNY KLRRCLFTLL GHLDYIRTAV FHHEYPWILS ASDDQTIRIW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Csv-025864|E3,WD_repeat;UBD,Beta-Prp|Ciona savignyi
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTTTTCCGT TTAAGGTATT TATTTTGCTG AAAGTTTAGG TAAGGCTTAA ATTACCTAAC 60
ATCTGAAATT CTTCAGAGAA GCAACCTTCA CAATTGAACA GCAGAATGCT GACGAAGTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Csv-025864|E3,WD_repeat;UBD,Beta-Prp|Ciona savignyi
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000064 Aegilops tauschii 56.55 0.00e+00 981.00
IUUC-Aml-001758 Ailuropoda melanoleuca 70.47 0.00e+00 1823.00
IUUC-Atr-002493 Amborella trichopoda 59.05 0.00e+00 1008.00
IUUC-Apl-003385 Anas platyrhynchos 68.85 0.00e+00 1490.00
IUUC-Aca-005154 Anolis carolinensis 78.34 6.00e-104 367.00
IUUC-Aly-006020 Arabidopsis lyrata 56.72 0.00e+00 985.00
IUUC-Ath-007360 Arabidopsis thaliana 57.41 0.00e+00 989.00
IUUC-Ago-007992 Ashbya gossypii 42.43 0.00e+00 944.00
IUUC-Acl-008027 Aspergillus clavatus 54.53 0.00e+00 950.00
IUUC-Afl-008644 Aspergillus flavus 54.95 0.00e+00 957.00
IUUC-Afu-008964 Aspergillus fumigatus 47.55 0.00e+00 1137.00
IUUC-Ani-009379 Aspergillus nidulans 55.07 0.00e+00 955.00
IUUC-Ang-009756 Aspergillus niger 55.32 0.00e+00 963.00
IUUC-Aor-010174 Aspergillus oryzae 54.95 0.00e+00 957.00
IUUC-Ame-011229 Astyanax mexicanus 74.61 0.00e+00 1301.00
IUUC-Bgr-012300 Blumeria graminis 46.17 0.00e+00 1074.00
IUUC-Bta-012524 Bos taurus 71.22 0.00e+00 1813.00
IUUC-Bci-013781 Botrytis cinerea 54.77 0.00e+00 950.00
IUUC-Bdi-014549 Brachypodium distachyon 56.43 0.00e+00 978.00
IUUC-Bol-015967 Brassica oleracea 57.26 0.00e+00 984.00
IUUC-Bra-016978 Brassica rapa 56.79 0.00e+00 981.00
IUUC-Cel-018115 Caenorhabditis elegans 60.12 0.00e+00 1038.00
IUUC-Cja-019107 Callithrix jacchus 69.27 0.00e+00 1782.00
IUUC-Cfa-020675 Canis familiaris 70.48 0.00e+00 1791.00
IUUC-Cpo-021813 Cavia porcellus 71.46 0.00e+00 1835.00
IUUC-Cre-022969 Chlamydomonas reinhardtii 60.24 0.00e+00 1029.00
IUUC-Csa-023523 Chlorocebus sabaeus 71.54 0.00e+00 1834.00
IUUC-Cho-024704 Choloepus hoffmanni 60.02 0.00e+00 1379.00
IUUC-Cin-025572 Ciona intestinalis 89.15 0.00e+00 2154.00
IUUC-Cgl-026510 Colletotrichum gloeosporioides 55.54 0.00e+00 969.00
IUUC-Cne-027053 Cryptococcus neoformans 55.71 0.00e+00 966.00
IUUC-Cme-027222 Cyanidioschyzon merolae 39.21 3.00e-134 471.00
IUUC-Dre-027421 Danio rerio 70.10 0.00e+00 1768.00
IUUC-Dno-029303 Dasypus novemcinctus 71.07 0.00e+00 1822.00
IUUC-Dor-030290 Dipodomys ordii 64.77 0.00e+00 714.00
IUUC-Dse-031543 Dothistroma septosporum 54.06 0.00e+00 932.00
IUUC-Dme-031945 Drosophila melanogaster 70.35 0.00e+00 1175.00
IUUC-Ete-032873 Echinops telfairi 68.01 0.00e+00 1605.00
IUUC-Eca-033773 Equus caballus 68.93 0.00e+00 1758.00
IUUC-Eeu-034874 Erinaceus europaeus 60.38 0.00e+00 1025.00
IUUC-Fca-035739 Felis catus 70.72 0.00e+00 1790.00
IUUC-Fal-037263 Ficedula albicollis 66.51 0.00e+00 1617.00
IUUC-Fox-037738 Fusarium oxysporum 47.82 0.00e+00 1154.00
IUUC-Fso-038153 Fusarium solani 47.85 0.00e+00 1135.00
IUUC-Gmo-039602 Gadus morhua 65.41 0.00e+00 1626.00
IUUC-Ggr-039931 Gaeumannomyces graminis 54.42 0.00e+00 958.00
IUUC-Gga-040590 Gallus gallus 71.72 0.00e+00 1821.00
IUUC-Gac-041318 Gasterosteus aculeatus 70.09 0.00e+00 1781.00
IUUC-Gma-043567 Glycine max 58.40 0.00e+00 993.00
IUUC-Ggo-045029 Gorilla gorilla 70.71 0.00e+00 1827.00
IUUC-Hsa-046078 Homo sapiens 70.71 0.00e+00 1828.00
IUUC-Hvu-047556 Hordeum vulgare 50.40 0.00e+00 1203.00
IUUC-Itr-048881 Ictidomys tridecemlineatus 68.17 0.00e+00 1207.00
IUUC-Kpa-049256 Komagataella pastoris 51.13 0.00e+00 875.00
IUUC-Lch-049706 Latimeria chalumnae 74.91 0.00e+00 1315.00
IUUC-Lpe-051316 Leersia perrieri 56.67 0.00e+00 981.00
IUUC-Loc-051867 Lepisosteus oculatus 59.84 0.00e+00 973.00
IUUC-Lma-053138 Leptosphaeria maculans 55.00 0.00e+00 959.00
IUUC-Laf-053510 Loxodonta africana 71.58 0.00e+00 1818.00
IUUC-Mcc-055836 Macaca mulatta 70.79 0.00e+00 1825.00
IUUC-Meu-056238 Macropus eugenii 66.91 0.00e+00 944.00
IUUC-Mor-057172 Magnaporthe oryzae 46.29 0.00e+00 1116.00
IUUC-Mpo-057300 Magnaporthe poae 54.18 0.00e+00 957.00
IUUC-Mtr-058248 Medicago truncatula 58.82 0.00e+00 1012.00
IUUC-Mla-059019 Melampsora laricipopulina 55.71 0.00e+00 976.00
IUUC-Mga-059499 Meleagris gallopavo 71.44 0.00e+00 1814.00
IUUC-Mvi-060336 Microbotryum violaceum 56.22 0.00e+00 988.00
IUUC-Mmr-061102 Microcebus murinus 71.11 0.00e+00 1819.00
IUUC-Mdo-062594 Monodelphis domestica 71.30 0.00e+00 1830.00
IUUC-Mmu-063736 Mus musculus 70.47 0.00e+00 1822.00
IUUC-Mac-065398 Musa acuminata 54.46 0.00e+00 905.00
IUUC-Mpu-066701 Mustela putorius furo 70.52 0.00e+00 1805.00
IUUC-Mlu-067392 Myotis lucifugus 71.00 0.00e+00 1814.00
IUUC-Nfi-068270 Neosartorya fischeri 55.09 0.00e+00 956.00
IUUC-Ncr-068892 Neurospora crassa 55.30 0.00e+00 966.00
IUUC-Nle-069634 Nomascus leucogenys 76.42 0.00e+00 1117.00
IUUC-Opr-070952 Ochotona princeps 60.04 0.00e+00 1240.00
IUUC-Ont-072488 Oreochromis niloticus 71.10 0.00e+00 1784.00
IUUC-Oan-073184 Ornithorhynchus anatinus 64.60 2.00e-63 233.00
IUUC-Ocu-074211 Oryctolagus cuniculus 71.38 0.00e+00 1831.00
IUUC-Oba-075761 Oryza barthii 56.67 0.00e+00 983.00
IUUC-Obr-076429 Oryza brachyantha 56.31 0.00e+00 976.00
IUUC-Ogl-077364 Oryza glaberrima 56.67 0.00e+00 983.00
IUUC-Ogu-078257 Oryza glumaepatula 56.67 0.00e+00 982.00
IUUC-Oin-080029 Oryza indica 56.90 0.00e+00 983.00
IUUC-Olo-080895 Oryza longistaminata 57.40 0.00e+00 979.00
IUUC-Ome-081993 Oryza meridionalis 58.86 0.00e+00 931.00
IUUC-Oni-082874 Oryza nivara 56.67 0.00e+00 983.00
IUUC-Opu-083885 Oryza punctata 56.90 0.00e+00 983.00
IUUC-Oru-084274 Oryza rufipogon 56.67 0.00e+00 983.00
IUUC-Osa-085841 Oryza sativa 57.02 0.00e+00 984.00
IUUC-Ola-086921 Oryzias latipes 69.01 0.00e+00 1789.00
IUUC-Olu-087639 Ostreococcus lucimarinus 60.48 0.00e+00 1030.00
IUUC-Oga-087991 Otolemur garnettii 67.68 0.00e+00 1719.00
IUUC-Oar-089590 Ovis aries 71.22 0.00e+00 1830.00
IUUC-Ptr-090808 Pan troglodytes 70.71 0.00e+00 1827.00
IUUC-Pan-092475 Papio anubis 71.16 0.00e+00 1821.00
IUUC-Psi-093044 Pelodiscus sinensis 64.76 0.00e+00 1074.00
IUUC-Pno-094839 Phaeosphaeria nodorum 53.94 0.00e+00 894.00
IUUC-Ppa-095254 Physcomitrella patens 62.23 0.00e+00 1058.00
IUUC-Pfo-097493 Poecilia formosa 71.10 0.00e+00 1785.00
IUUC-Pab-098497 Pongo abelii 71.46 0.00e+00 1833.00
IUUC-Pop-100086 Populus trichocarpa 58.82 0.00e+00 1000.00
IUUC-Pca-100413 Procavia capensis 67.20 0.00e+00 805.00
IUUC-Ppe-101899 Prunus persica 58.82 0.00e+00 1011.00
IUUC-Pva-102126 Pteropus vampyrus 68.32 0.00e+00 1745.00
IUUC-Pgr-103376 Puccinia graminis 49.56 0.00e+00 1210.00
IUUC-Ptt-103978 Puccinia triticina 49.18 0.00e+00 749.00
IUUC-Pte-104126 Pyrenophora teres 54.72 0.00e+00 926.00
IUUC-Pyt-104778 Pyrenophora triticirepentis 45.70 5.00e-170 590.00
IUUC-Rno-105428 Rattus norvegicus 71.64 0.00e+00 1833.00
IUUC-Sce-106464 Saccharomyces cerevisiae 42.56 0.00e+00 925.00
IUUC-Sha-107301 Sarcophilus harrisii 71.00 0.00e+00 1807.00
IUUC-Sja-107961 Schizosaccharomyces japonicus 44.35 0.00e+00 1040.00
IUUC-Spo-108217 Schizosaccharomyces pombe 45.33 0.00e+00 1085.00
IUUC-Ssl-108643 Sclerotinia sclerotiorum 55.01 0.00e+00 953.00
IUUC-Smo-109582 Selaginella moellendorffii 60.93 0.00e+00 1042.00
IUUC-Sit-109697 Setaria italica 56.90 0.00e+00 984.00
IUUC-Sly-111759 Solanum lycopersicum 58.01 0.00e+00 1002.00
IUUC-Stu-112564 Solanum tuberosum 57.89 0.00e+00 999.00
IUUC-Sar-113313 Sorex araneus 62.56 0.00e+00 1038.00
IUUC-Sbi-114388 Sorghum bicolor 50.36 0.00e+00 1211.00
IUUC-Sre-115209 Sporisorium reilianum 56.11 0.00e+00 980.00
IUUC-Ssc-115933 Sus scrofa 71.38 0.00e+00 1831.00
IUUC-Tgu-117109 Taeniopygia guttata 60.65 5.00e-150 522.00
IUUC-Tru-117772 Takifugu rubripes 69.18 0.00e+00 1730.00
IUUC-Tsy-119105 Tarsius syrichta 62.28 0.00e+00 1553.00
IUUC-Tni-120556 Tetraodon nigroviridis 56.71 0.00e+00 1183.00
IUUC-Tca-121545 Theobroma cacao 59.36 0.00e+00 1011.00
IUUC-Tre-121951 Trichoderma reesei 55.78 0.00e+00 956.00
IUUC-Tvi-122359 Trichoderma virens 56.14 0.00e+00 970.00
IUUC-Tae-125527 Triticum aestivum 56.55 0.00e+00 981.00
IUUC-Tur-126754 Triticum urartu 56.43 0.00e+00 979.00
IUUC-Tme-127170 Tuber melanosporum 48.36 0.00e+00 1155.00
IUUC-Tbe-127882 Tupaia belangeri 53.91 3.00e-177 614.00
IUUC-Ttr-128217 Tursiops truncatus 68.72 0.00e+00 1759.00
IUUC-Uma-129337 Ustilago maydis 55.58 0.00e+00 978.00
IUUC-Vda-129828 Verticillium dahliae 46.85 0.00e+00 1116.00
IUUC-Vpa-130537 Vicugna pacos 70.05 0.00e+00 1797.00
IUUC-Vvi-130958 Vitis vinifera 58.70 0.00e+00 1003.00
IUUC-Xtr-132857 Xenopus tropicalis 67.88 0.00e+00 1677.00
IUUC-Xma-133138 Xiphophorus maculatus 70.85 0.00e+00 1782.00
IUUC-Yli-134399 Yarrowia lipolytica 49.71 0.00e+00 814.00
IUUC-Zma-135612 Zea mays 47.78 0.00e+00 1183.00
Created Date 25-Jun-2017

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