iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118099

UUCD1 version

UUC-TaR-00141

Ensembl Protein ID

ENSTRUP00000007326.1

UniProt Accession

H2S4K4; H2S4K4_TAKRU

Protein Name

Uncharacterized protein

Gene Name

KBTBD12 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000003125.1	ENSTRUT00000007371.1	ENSTRUP00000007326.1
ENSTRUG00000003125.1	ENSTRUT00000007372.1	ENSTRUP00000007327.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.20e-16	60.3	24	89
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.70e-06	25.7	123	153

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l  +g+ f++hk+vL+a S +F+a+f+ +l+e++ + +v ++dv +++++ ll+++Y g l++
   Q: 24   TDVVLLTEGVAFHCHKVVLSAFSAYFQAMFTCGLRETQ-GAEVLLRDVPAKCLQLLLDYMYQGNLPL 89
           7************************************9.*************************997 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nc+g+++ A+ ++++ L+d al+++++hF
   Q: 123  PSNCVGLYHWARNMGATGLADCALRYMCQHF 153
           89***************************** PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

SAQAEHGSHL LMYLQRMRAT QELTDVVLLT EGVAFHCHKV VLSAFSAYFQ AMFTCGLRET 60
QGAEVLLRDV PAKCLQLLLD YMYQGNLPLD NDNIQAVAAA AFLLDVDGAF RICQNHMEAN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGGCTCAGG CAGAGCACGG TTCACACCTG CTCATGTACT TGCAGAGGAT GAGGGCGACG 60
CAAGAGCTCA CCGACGTGGT CCTCCTGACA GAGGGTGTTG CTTTTCACTG CCACAAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030583--KBTBD12
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Mac-065468	Musa acuminata	27.51	2.00e-13	70.90
IUUC-Ont-071341	Oreochromis niloticus	79.54	0.00e+00	926.00
IUUC-Ola-087186	Oryzias latipes	73.93	0.00e+00	815.00
IUUC-Pfo-097513	Poecilia formosa	76.44	0.00e+00	838.00
IUUC-Sly-111467	Solanum lycopersicum	36.84	7.00e-10	58.50
IUUC-Tni-120396	Tetraodon nigroviridis	84.63	0.00e+00	1020.00
IUUC-Tur-126663	Triticum urartu	33.93	1.00e-10	61.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence