iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006876

UUCD1 version

UUC-ArT-01639

Ensembl Protein ID

AT4G36800.2

UniProt Accession

Q9SDY5; O23202; Q0WLB1; RCE1_ARATH

Genbank Protein ID

AAF19827.1; CAB16820.1; CAB80346.1; AEE86703.1; AEE86704.1; AAK82473.1; AAM19897.1; BAF02096.1

Protein Name

NEDD8-conjugating enzyme Ubc12; RUB1 carrier protein 1; RUB1-conjugating enzyme 1; RUB1-protein ligase 1

Genbank Nucleotide ID

AF202771; Z99708; AL161590; CP002687; CP002687; AY048210; AY097381; AK230295

Gene Name

RCE1; At4g36800; C7A10.560

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G36800	AT4G36800.2	AT4G36800.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	19218398; 12682009; 17220175

Classification

Family	E-value	Score	Start	End
E2/UBC	2.30e-37	128.8	34	167

Active Site

Position(s)	Description	Evidence
113	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           Rl+k+++el+  ++ +is    ++ dl+++ev i  p+d +Y++g+F +++++++ YP ++Pkvk+ tk++hPn++ +G+vCl+il+  e+W+p+l++
   Q: 34   RLHKDISELNLPSSCSISFPNGKD-DLMNFEVSIK-PDDGYYHNGTFVFTFQVSPVYPHEAPKVKCKTKVYHPNIDLEGNVCLNILR--EDWKPVLNI 127
           899*****9766666666655555.8*********.**************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++v++++  l++epn e+pln++aa  l++n++ ++++vr
   Q: 128  NTVIYGLFHLFTEPNSEDPLNHDAAAVLRDNPKLFETNVR 167
           **************************************98 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MIGLFKVKEK QREQAQNATR GGASVKKQSA GELRLHKDIS ELNLPSSCSI SFPNGKDDLM 60
NFEVSIKPDD GYYHNGTFVF TFQVSPVYPH EAPKVKCKTK VYHPNIDLEG NVCLNILRED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCAACCA TTTCTCTGCT GTTTCTTCGT CGTTTAGCTT CAGAGGACGA CAATCCGGTA 60
GGCGAGAGAG AGAGATTAAT CAATCGGCGA CCTTTTTAAT TCGCTCGTAA TTCGTTTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0016874--F:ligase activity
GO:0019788--F:NEDD8 transferase activity
GO:0045116--P:protein neddylation
GO:0009733--P:response to auxin

KEGG

ath:AT4G36800

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000196	Aegilops tauschii	78.23	4.00e-69	252.00
IUUC-Aml-002007	Ailuropoda melanoleuca	65.99	9.00e-57	211.00
IUUC-Atr-003170	Amborella trichopoda	86.41	3.00e-94	336.00
IUUC-Aca-005037	Anolis carolinensis	60.33	2.00e-65	240.00
IUUC-Aly-005638	Arabidopsis lyrata	100.00	2.00e-109	386.00
IUUC-Ago-007910	Ashbya gossypii	44.97	2.00e-34	137.00
IUUC-Ani-009422	Aspergillus nidulans	57.24	2.00e-49	187.00
IUUC-Ame-011382	Astyanax mexicanus	61.08	1.00e-66	244.00
IUUC-Bgr-012306	Blumeria graminis	51.67	2.00e-53	200.00
IUUC-Bci-013626	Botrytis cinerea	50.00	6.00e-53	199.00
IUUC-Bdi-014528	Brachypodium distachyon	78.14	2.00e-81	293.00
IUUC-Bol-015241	Brassica oleracea	97.84	1.00e-106	377.00
IUUC-Bra-016704	Brassica rapa	97.84	1.00e-106	377.00
IUUC-Cre-022865	Chlamydomonas reinhardtii	63.27	1.00e-53	201.00
IUUC-Dor-030851	Dipodomys ordii	39.52	1.00e-28	118.00
IUUC-Dse-031265	Dothistroma septosporum	55.43	2.00e-53	201.00
IUUC-Dme-032076	Drosophila melanogaster	57.61	4.00e-61	226.00
IUUC-Ete-032350	Echinops telfairi	47.37	1.00e-27	113.00
IUUC-Fca-035654	Felis catus	65.99	9.00e-57	211.00
IUUC-Gmo-039402	Gadus morhua	61.08	3.00e-66	243.00
IUUC-Gma-043805	Glycine max	87.50	4.00e-96	342.00
IUUC-Hvu-047056	Hordeum vulgare	74.86	1.00e-81	294.00
IUUC-Kpa-049315	Komagataella pastoris	46.89	8.00e-46	175.00
IUUC-Lpe-050743	Leersia perrieri	81.50	4.00e-82	296.00
IUUC-Laf-053463	Loxodonta africana	65.31	3.00e-56	209.00
IUUC-Meu-056085	Macropus eugenii	65.07	6.00e-56	208.00
IUUC-Mtr-058251	Medicago truncatula	85.87	6.00e-95	338.00
IUUC-Mvi-060449	Microbotryum violaceum	57.72	1.00e-49	188.00
IUUC-Mac-064967	Musa acuminata	83.15	2.00e-90	324.00
IUUC-Mlu-066955	Myotis lucifugus	64.90	3.00e-57	213.00
IUUC-Ncr-068944	Neurospora crassa	59.21	3.00e-50	190.00
IUUC-Nle-069051	Nomascus leucogenys	65.99	9.00e-57	211.00
IUUC-Opr-070635	Ochotona princeps	65.75	3.00e-56	209.00
IUUC-Ont-072348	Oreochromis niloticus	61.08	4.00e-66	243.00
IUUC-Oba-075825	Oryza barthii	81.42	7.00e-88	315.00
IUUC-Obr-076067	Oryza brachyantha	80.87	2.00e-87	314.00
IUUC-Ogl-077594	Oryza glaberrima	81.42	7.00e-88	315.00
IUUC-Ogu-078073	Oryza glumaepatula	81.42	7.00e-88	315.00
IUUC-Oin-080060	Oryza indica	73.37	3.00e-78	284.00
IUUC-Olo-080314	Oryza longistaminata	81.42	5.00e-88	315.00
IUUC-Ome-081713	Oryza meridionalis	81.42	6.00e-88	315.00
IUUC-Oni-082426	Oryza nivara	81.42	7.00e-88	315.00
IUUC-Opu-083942	Oryza punctata	81.61	5.00e-83	298.00
IUUC-Oru-085104	Oryza rufipogon	81.42	7.00e-88	315.00
IUUC-Osa-086168	Oryza sativa	81.42	7.00e-88	315.00
IUUC-Olu-087854	Ostreococcus lucimarinus	61.96	8.00e-64	235.00
IUUC-Oar-089623	Ovis aries	62.84	4.00e-51	192.00
IUUC-Ptr-091020	Pan troglodytes	65.75	3.00e-56	209.00
IUUC-Pan-092119	Papio anubis	65.99	9.00e-57	211.00
IUUC-Psi-093494	Pelodiscus sinensis	65.31	1.00e-56	211.00
IUUC-Pop-099484	Populus trichocarpa	85.87	1.00e-95	340.00
IUUC-Pca-100300	Procavia capensis	65.07	9.00e-56	207.00
IUUC-Ppe-101216	Prunus persica	85.87	8.00e-88	315.00
IUUC-Sce-106385	Saccharomyces cerevisiae	47.37	3.00e-37	147.00
IUUC-Sha-106899	Sarcophilus harrisii	65.31	2.00e-56	210.00
IUUC-Smo-109330	Selaginella moellendorffii	68.48	1.00e-77	281.00
IUUC-Sit-109702	Setaria italica	79.78	1.00e-79	287.00
IUUC-Sly-111045	Solanum lycopersicum	84.78	2.00e-93	333.00
IUUC-Stu-112655	Solanum tuberosum	83.15	7.00e-92	328.00
IUUC-Sbi-114357	Sorghum bicolor	78.69	3.00e-78	283.00
IUUC-Tni-119674	Tetraodon nigroviridis	51.89	3.00e-51	193.00
IUUC-Tca-121359	Theobroma cacao	86.96	4.00e-95	339.00
IUUC-Tae-125117	Triticum aestivum	75.41	7.00e-82	295.00
IUUC-Tur-126125	Triticum urartu	74.86	2.00e-82	297.00
IUUC-Tbe-127874	Tupaia belangeri	42.93	4.00e-35	139.00
IUUC-Ttr-128213	Tursiops truncatus	62.20	7.00e-57	211.00
IUUC-Vvi-131182	Vitis vinifera	86.41	5.00e-95	339.00
IUUC-Xtr-132742	Xenopus tropicalis	60.33	4.00e-65	239.00
IUUC-Yli-134467	Yarrowia lipolytica	53.89	6.00e-55	205.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence