iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027450

UUCD1 version

UUC-DaR-01368

Ensembl Protein ID

ENSDARP00000107407.2

UniProt Accession

Q7ZUF3; Q7ZUF3_DANRE

Genbank Protein ID

AAH49139.1; AAI65255.1

Protein Name

Ube2h protein; Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

Genbank Nucleotide ID

AL590150; BC165255

Gene Name

ube2h

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000000019.8	ENSDART00000124452.2	ENSDARP00000107407.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.90e-34	118.7	30	143

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 26   dltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesvlls.iqsllaep 112
            l+e+ v++ Gp++tpYeggv+k+++++p++YPfk+P++ f++kifhPn++e+ G+vCl++++  ++W++ +++++++ s + +lla p
   Q: 30   GLNEFVVKFYGPQGTPYEGGVWKVRVDLPDKYPFKSPSIGFMNKIFHPNIDEAsGTVCLDVIN--QTWTALYDLTNIFESfLPQLLAYP 116
           4889************************************************99********9..*************66378999*** PP
   S: 113  npesplneeaaellkknreeykkkvre 139
           np +pln +aa ++ +++e+yk+k++e
   Q: 117  NPIDPLNGDAAAMYLHRPEDYKQKIKE 143
           ************************985 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSSPSPGKRR MDTDVVKLIE SKHEVTILSG LNEFVVKFYG PQGTPYEGGV WKVRVDLPDK 60
YPFKSPSIGF MNKIFHPNID EASGTVCLDV INQTWTALYD LTNIFESFLP QLLAYPNPID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACGACAGC TTGCCGTATG CCAATGTTCA AAAATACTCA GTTTCGGTAG AGGCCAAGGG 60
ATCGAGAATC AGTCGCAGAA GATTTGAGCA TCGGTCATCT GAAAGAGGAG TGTATAAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:368425

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000745	Aegilops tauschii	60.13	2.00e-52	198.00
IUUC-Aml-001260	Ailuropoda melanoleuca	98.36	5.00e-85	306.00
IUUC-Atr-002681	Amborella trichopoda	58.06	1.00e-52	198.00
IUUC-Apl-003547	Anas platyrhynchos	97.58	8.00e-72	262.00
IUUC-Aca-005224	Anolis carolinensis	98.18	1.00e-73	268.00
IUUC-Aly-005836	Arabidopsis lyrata	57.79	7.00e-52	196.00
IUUC-Ath-007534	Arabidopsis thaliana	57.79	5.00e-52	197.00
IUUC-Ago-007727	Ashbya gossypii	60.39	3.00e-52	197.00
IUUC-Acl-008119	Aspergillus clavatus	60.71	1.00e-56	212.00
IUUC-Afl-008412	Aspergillus flavus	62.10	4.00e-46	176.00
IUUC-Afu-008925	Aspergillus fumigatus	57.06	2.00e-53	202.00
IUUC-Ani-009294	Aspergillus nidulans	58.39	9.00e-52	196.00
IUUC-Ang-009805	Aspergillus niger	62.50	2.00e-56	211.00
IUUC-Aor-010201	Aspergillus oryzae	54.43	1.00e-47	182.00
IUUC-Ate-010441	Aspergillus terreus	66.67	5.00e-47	179.00
IUUC-Ame-010807	Astyanax mexicanus	75.96	5.00e-63	232.00
IUUC-Bta-012802	Bos taurus	98.36	5.00e-85	306.00
IUUC-Bdi-014415	Brachypodium distachyon	60.78	1.00e-52	198.00
IUUC-Bol-016385	Brassica oleracea	59.33	4.00e-51	193.00
IUUC-Bra-016989	Brassica rapa	59.33	1.00e-50	192.00
IUUC-Cel-018412	Caenorhabditis elegans	67.10	9.00e-66	243.00
IUUC-Cja-019571	Callithrix jacchus	73.94	5.00e-62	229.00
IUUC-Cfa-020811	Canis familiaris	98.36	5.00e-85	306.00
IUUC-Cpo-021889	Cavia porcellus	90.71	2.00e-75	274.00
IUUC-Cre-022956	Chlamydomonas reinhardtii	58.17	9.00e-52	196.00
IUUC-Csa-023289	Chlorocebus sabaeus	98.36	5.00e-85	306.00
IUUC-Cho-024517	Choloepus hoffmanni	76.50	9.00e-55	206.00
IUUC-Cin-025571	Ciona intestinalis	62.89	9.00e-54	202.00
IUUC-Cgl-026627	Colletotrichum gloeosporioides	65.12	7.00e-52	196.00
IUUC-Cne-027006	Cryptococcus neoformans	58.21	2.00e-47	182.00
IUUC-Cme-027171	Cyanidioschyzon merolae	60.00	3.00e-53	201.00
IUUC-Dno-029838	Dasypus novemcinctus	98.36	5.00e-85	306.00
IUUC-Dor-031119	Dipodomys ordii	98.36	5.00e-85	306.00
IUUC-Dse-031243	Dothistroma septosporum	61.78	3.00e-57	214.00
IUUC-Dme-031807	Drosophila melanogaster	77.60	2.00e-76	278.00
IUUC-Ete-032437	Echinops telfairi	74.86	1.00e-62	231.00
IUUC-Eca-034123	Equus caballus	98.27	1.00e-78	285.00
IUUC-Eeu-034543	Erinaceus europaeus	94.12	3.00e-34	137.00
IUUC-Fca-035502	Felis catus	98.36	5.00e-85	306.00
IUUC-Fal-037054	Ficedula albicollis	98.18	2.00e-74	271.00
IUUC-Fox-037912	Fusarium oxysporum	69.70	4.00e-41	159.00
IUUC-Fso-038148	Fusarium solani	61.18	2.00e-51	194.00
IUUC-Gmo-038858	Gadus morhua	96.72	7.00e-92	329.00
IUUC-Ggr-039749	Gaeumannomyces graminis	60.99	2.00e-48	184.00
IUUC-Gga-040942	Gallus gallus	98.36	5.00e-85	306.00
IUUC-Gac-042079	Gasterosteus aculeatus	96.17	5.00e-91	326.00
IUUC-Gma-042856	Glycine max	62.75	1.00e-54	205.00
IUUC-Hsa-046545	Homo sapiens	98.36	5.00e-85	306.00
IUUC-Hvu-047746	Hordeum vulgare	60.14	3.00e-49	187.00
IUUC-Itr-048474	Ictidomys tridecemlineatus	98.36	5.00e-85	306.00
IUUC-Kpa-049144	Komagataella pastoris	65.91	8.00e-50	189.00
IUUC-Lch-050589	Latimeria chalumnae	91.80	1.00e-75	275.00
IUUC-Lpe-051335	Leersia perrieri	60.13	5.00e-52	196.00
IUUC-Loc-052829	Lepisosteus oculatus	97.81	5.00e-80	290.00
IUUC-Lma-052971	Leptosphaeria maculans	60.31	4.00e-46	177.00
IUUC-Laf-053526	Loxodonta africana	96.72	6.00e-83	299.00
IUUC-Mcc-055611	Macaca mulatta	98.36	5.00e-85	306.00
IUUC-Meu-056722	Macropus eugenii	58.18	5.00e-35	140.00
IUUC-Mor-057278	Magnaporthe oryzae	67.46	3.00e-52	197.00
IUUC-Mpo-057484	Magnaporthe poae	65.22	3.00e-46	177.00
IUUC-Mtr-058579	Medicago truncatula	59.35	2.00e-53	201.00
IUUC-Mla-058926	Melampsora laricipopulina	64.24	2.00e-57	214.00
IUUC-Mga-059801	Meleagris gallopavo	98.36	5.00e-85	306.00
IUUC-Mvi-060244	Microbotryum violaceum	61.94	7.00e-56	209.00
IUUC-Mmr-061205	Microcebus murinus	98.36	5.00e-85	306.00
IUUC-Mdo-062038	Monodelphis domestica	98.23	2.00e-42	164.00
IUUC-Mmu-063974	Mus musculus	98.36	5.00e-85	306.00
IUUC-Mac-065158	Musa acuminata	63.87	3.00e-56	210.00
IUUC-Mpu-066759	Mustela putorius furo	98.36	5.00e-85	306.00
IUUC-Mlu-067674	Myotis lucifugus	92.78	1.00e-74	271.00
IUUC-Nfi-068618	Neosartorya fischeri	62.41	2.00e-51	194.00
IUUC-Ncr-068712	Neurospora crassa	69.17	8.00e-51	192.00
IUUC-Nle-069926	Nomascus leucogenys	98.36	5.00e-85	306.00
IUUC-Opr-070598	Ochotona princeps	98.36	5.00e-85	306.00
IUUC-Ont-071893	Oreochromis niloticus	97.81	4.00e-89	320.00
IUUC-Oan-073273	Ornithorhynchus anatinus	98.18	2.00e-74	271.00
IUUC-Ocu-074357	Oryctolagus cuniculus	99.25	7.00e-78	282.00
IUUC-Oba-075055	Oryza barthii	60.13	5.00e-52	196.00
IUUC-Obr-076538	Oryza brachyantha	59.48	9.00e-52	196.00
IUUC-Ogl-077784	Oryza glaberrima	60.13	5.00e-52	196.00
IUUC-Ogu-078045	Oryza glumaepatula	60.13	5.00e-52	196.00
IUUC-Oin-079163	Oryza indica	60.13	5.00e-52	196.00
IUUC-Olo-080847	Oryza longistaminata	54.79	1.00e-43	169.00
IUUC-Ome-081586	Oryza meridionalis	55.76	1.00e-49	189.00
IUUC-Oni-082913	Oryza nivara	60.13	5.00e-52	196.00
IUUC-Opu-083651	Oryza punctata	60.13	5.00e-52	196.00
IUUC-Oru-084980	Oryza rufipogon	60.13	5.00e-52	196.00
IUUC-Osa-085334	Oryza sativa	60.14	1.00e-48	185.00
IUUC-Ola-087423	Oryzias latipes	97.81	2.00e-93	334.00
IUUC-Oga-088412	Otolemur garnettii	98.36	5.00e-85	306.00
IUUC-Oar-090282	Ovis aries	95.91	6.00e-75	273.00
IUUC-Ptr-090470	Pan troglodytes	98.36	5.00e-85	306.00
IUUC-Pan-092552	Papio anubis	98.36	5.00e-85	306.00
IUUC-Psi-093516	Pelodiscus sinensis	91.30	1.00e-75	275.00
IUUC-Pno-094800	Phaeosphaeria nodorum	68.27	1.00e-43	169.00
IUUC-Ppa-095962	Physcomitrella patens	58.71	1.00e-53	202.00
IUUC-Pfo-097374	Poecilia formosa	98.91	1.00e-85	308.00
IUUC-Pab-098112	Pongo abelii	98.36	5.00e-85	306.00
IUUC-Pop-099923	Populus trichocarpa	61.29	5.00e-54	203.00
IUUC-Pca-100436	Procavia capensis	80.99	5.00e-63	233.00
IUUC-Ppe-101144	Prunus persica	61.94	4.00e-54	204.00
IUUC-Pva-102776	Pteropus vampyrus	97.81	4.00e-83	300.00
IUUC-Pgr-103325	Puccinia graminis	63.97	3.00e-52	197.00
IUUC-Ptt-104010	Puccinia triticina	62.41	1.00e-47	182.00
IUUC-Pte-104024	Pyrenophora teres	56.40	1.00e-53	202.00
IUUC-Pyt-104715	Pyrenophora triticirepentis	64.39	4.00e-51	193.00
IUUC-Rno-105699	Rattus norvegicus	97.27	1.00e-83	302.00
IUUC-Sce-106165	Saccharomyces cerevisiae	60.94	3.00e-43	168.00
IUUC-Sha-106524	Sarcophilus harrisii	98.18	4.00e-74	270.00
IUUC-Sja-107813	Schizosaccharomyces japonicus	61.59	2.00e-53	201.00
IUUC-Spo-108105	Schizosaccharomyces pombe	60.78	3.00e-54	204.00
IUUC-Ssl-108543	Sclerotinia sclerotiorum	55.48	4.00e-47	180.00
IUUC-Smo-108971	Selaginella moellendorffii	63.33	1.00e-55	208.00
IUUC-Sit-110211	Setaria italica	60.13	9.00e-52	197.00
IUUC-Sly-111324	Solanum lycopersicum	61.29	2.00e-54	204.00
IUUC-Stu-112525	Solanum tuberosum	60.13	2.00e-53	201.00
IUUC-Sar-113572	Sorex araneus	78.79	4.00e-49	187.00
IUUC-Sbi-113911	Sorghum bicolor	60.13	2.00e-52	197.00
IUUC-Sre-115027	Sporisorium reilianum	62.34	3.00e-58	217.00
IUUC-Ssc-116221	Sus scrofa	97.69	1.00e-76	278.00
IUUC-Tgu-116965	Taeniopygia guttata	98.18	5.00e-74	269.00
IUUC-Tru-117574	Takifugu rubripes	97.27	3.00e-80	290.00
IUUC-Tni-120422	Tetraodon nigroviridis	97.27	2.00e-80	291.00
IUUC-Tca-121140	Theobroma cacao	63.23	2.00e-55	208.00
IUUC-Tre-122110	Trichoderma reesei	64.89	2.00e-50	191.00
IUUC-Tvi-122592	Trichoderma virens	58.28	6.00e-49	186.00
IUUC-Tae-123161	Triticum aestivum	60.13	2.00e-52	198.00
IUUC-Tur-126414	Triticum urartu	59.48	5.00e-52	196.00
IUUC-Tme-127020	Tuber melanosporum	54.89	9.00e-40	155.00
IUUC-Tbe-128053	Tupaia belangeri	82.42	3.00e-54	204.00
IUUC-Ttr-128734	Tursiops truncatus	98.36	5.00e-85	306.00
IUUC-Uma-129334	Ustilago maydis	62.34	2.00e-58	218.00
IUUC-Vda-129953	Verticillium dahliae	57.74	3.00e-53	201.00
IUUC-Vpa-130729	Vicugna pacos	98.18	5.00e-74	269.00
IUUC-Vvi-131055	Vitis vinifera	60.13	1.00e-54	205.00
IUUC-Xtr-132368	Xenopus tropicalis	97.27	5.00e-84	303.00
IUUC-Xma-133864	Xiphophorus maculatus	98.91	1.00e-85	308.00
IUUC-Yli-134339	Yarrowia lipolytica	57.42	3.00e-56	210.00
IUUC-Zma-135728	Zea mays	59.18	2.00e-49	188.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence