iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041566

Ensembl Protein ID

ENSGACP00000021424.1

UniProt Accession

G3PUY7; G3PUY7_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000016237.1	ENSGACT00000021465.1	ENSGACP00000021424.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	2.70e-143	477.2	170	472
E3 adaptor/Cullin RING/DCX/DWD	1.30e-26	91.9	305	340

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWs+ n l+v+Lg++vylwsa+t++v++l+dl  ++d+vtsv w e+g+l+avGt+kg v+i+D++  +k
   Q: 170  PFKVLDAPELQDDFYLNLVDWSAGNLLSVGLGACVYLWSACTSQVTRLCDLsVDGDSVTSVCWNERGSLVAVGTHKGYVQIWDAAGGRK 258
           689************************************************999*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfke 177
           + +l+ghsarvgaL+Wn e+lssGsrd+ il+rdvr++    ++lq+h+qevCGlkw+ d+++LasGGnDn++ vw++ss  P++++++
   Q: 259  LTSLEGHSARVGALAWNGEQLSSGSRDRVILQRDVRTSPSAERRLQGHRQEVCGLKWSPDHQHLASGGNDNKLLVWNSSSLLPVQQYSD 347
           ***************************************************************************************** PP
   S: 178  hkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           h aavkaiawsP+q++lLasGGGtaDrc++fwntltg+ l++ dtgsqvc+l+wsk+++elvsthG+++n++ +wkypsl++va+l+gh
   Q: 348  HLAAVKAIAWSPHQHGLLASGGGTADRCLRFWNTLTGQALQSTDTGSQVCNLAWSKHANELVSTHGYSQNQVLVWKYPSLTQVAKLTGH 436
           ***************************************************************************************** PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ++Rvl+la+spdgeaivt+agDetlrfw++f+k++ 
   Q: 437  SYRVLYLAVSPDGEAIVTGAGDETLRFWNVFSKTRC 472
           ********************************9875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH  +v++l++ +d  +l+sG++D+++ vW+ ++  
   Q: 305  GHRQEVCGLKWsPDhQHLASGGNDNKLLVWNSSSLL 340
           8***********999***************976655 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MDQEYERRLL RQINHQNLPT EARLSKCGSA TCSPVSIRSG DRFIPTRAGS NWSINFHYAN 60
ENCRSPNQTH KVKDATSDSS KDAVAYAALL RNELLGAGIE SVPDTHTDDR RPSVRSQDSH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCAAG AGTACGAGAG ACGGCTGCTG AGGCAAATCA ACCACCAGAA CCTGCCGACA 60
GAGGCCCGCC TGTCAAAGGT CAGGCGCAGG GAATGATGGG AAATCCTTTC ATGGTTGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011773	Astyanax mexicanus	91.17	0.00e+00	918.00
IUUC-Dre-027860	Danio rerio	91.17	0.00e+00	921.00
IUUC-Fox-037814	Fusarium oxysporum	64.17	9.00e-124	436.00
IUUC-Gmo-039431	Gadus morhua	86.24	0.00e+00	874.00
IUUC-Loc-052240	Lepisosteus oculatus	85.42	0.00e+00	863.00
IUUC-Ont-071725	Oreochromis niloticus	96.10	0.00e+00	969.00
IUUC-Ola-086983	Oryzias latipes	92.89	0.00e+00	937.00
IUUC-Pfo-096991	Poecilia formosa	92.61	0.00e+00	895.00
IUUC-Tru-118528	Takifugu rubripes	92.49	0.00e+00	895.00
IUUC-Tni-120312	Tetraodon nigroviridis	93.24	0.00e+00	894.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence