iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptt-103928

Ensembl Protein ID

PTTG_07616P0

UniProt Accession

A0A180G665; A0A180G665_PUCT1

Genbank Protein ID

OAV88146.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

ADAS02000206

Gene Name

PTTG_07616

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTTG_07616	PTTG_07616T0	PTTG_07616P0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.90e-49	165.7	267	779
UBD/Alpha-Helix/UBA	1.10e-17	62.8	631	669

Active Site

Position(s)	Description	Evidence
322	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
777	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 7    gNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeel...........................wkskkkavspre 72
           g  CY+ SvLQ+L+++p++++ +++     +++++++    +p  ++ +++ k+ + +                           +ks ++ ++p +
   Q: 267  GENCYIASVLQVLFALPPFQKRYFQgifeLHSSTCEA---ASPADCFDCQMSKIAHGMlsgryavsrctgeengardgshvpaqaTKSFQEGIKPMM 360
           778*****************99999977666667765...57899*************999999999999999999988888765599999****** PP
   S: 73   llkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepf 169
           +++ ++k ++efs+++qqDa Ef+++l++ ++++  +   +p             + +  +   +++   +  F+++l+++++c +c+ v  r+e+ 
   Q: 361  FKAFVGKGHPEFSTMRQQDADEFMRYLFQFIQRQARQ---SPA------------KASLLSALAESDLDPTLPFRFELEEKLQCTSCQCVRYRYEEQ 442
           ***********************************22...222............223345667777788899************************ PP
   S: 170  ldlslpvpgkeetkke..................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
             lslpvp    t +                   sl++cLesft+++++e    y+c++ck+k++a  + ++ ++P++L +h  Rf     +++++k
   Q: 443  EALSLPVPAVPVTPPAepesagitppgqttyqpvSLEECLESFTTPQTVE----YNCPRCKSKTTALTTSRIASFPKYLAIHTRRF--AIVNWVPKK 533
           ********88877555889999999999999999***************9....********************************..5577***** PP
   S: 249  inkkvefple.Ldlspfcts............................................................................. 267
           ++  v +  + +dl+++  +                                                                             
   Q: 534  LEIPVIIQGHqVDLEKYFGRgiqpgeetlpeveerapevsvnpetlsalesmgfptakcrkailetgdsgvesatswlfehmddvevaeapsaqvsh 630
           ********989*****999989999999988888888888888888888888887777777777777777777777777777777776666666655 PP
   S: 268  .............peekqke...........................................................kkkYeLiavvvHsG.sls 291
                        +     +                                                           + +++L + ++H+G s+ 
   Q: 631  neehvsmlmdmgfT-----SnqakkalgetdgnveravewlfshpdddgstianvgstvtsepagaavqngtrvgdkslPARFKLRGFISHKGpSVF 722
           55555555555550.....055555666666667777777777777777777788888888888888888888889999****************** PP
   S: 292  sGHYvayvkn..........ekgkWllfdDskVtevkeeevleetg..staYvlfYkr 337
           sGHYva+v++          + ++W+lf+D+kV + ++      ++    aY+++++r
   Q: 723  SGHYVAHVNSnlpahspsalKGEHWVLFNDEKVAVAEQGPLSH-EAmaPLAYIYLFER 779
           **********78777777644555*********9996655554.44579999999986 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           +e+ +  l++MGF+ ++a++aL ++++n+e+Ave+L+++
   Q: 631  NEEHVSMLMDMGFTSNQAKKALGETDGNVERAVEWLFSH 669
           789999*******************************97 PP

Organism

Puccinia triticina

Protein Sequence
(Fasta)

MAQSGLHPLA ALLNQVNLPT ARSVVYREEC TQCFDSQDSP SGIDVCLTCF NGGCVHFKHA 60
SNHAQKTGHR LAMNVQRTRK PDSHQRSPSA EPPLKKLAIT EQTEDQFDTK TLLVHYASAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCAAT CTGGCCTCCA TCCGTTGGCT GCACTCCTGA ACCAGGTCAA TTTGCCCACC 60
GCTCGCTCTG TCGTTTACCG TGAGGAATGT ACCCAATGTT TTGGTGAGTT GATGATATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	30.62	2.00e-71	261.00
IUUC-Aml-002104	Ailuropoda melanoleuca	30.40	1.00e-106	378.00
IUUC-Atr-002580	Amborella trichopoda	29.61	2.00e-89	322.00
IUUC-Apl-003774	Anas platyrhynchos	30.41	3.00e-102	364.00
IUUC-Aca-005368	Anolis carolinensis	30.60	2.00e-109	387.00
IUUC-Aly-005727	Arabidopsis lyrata	29.29	2.00e-90	324.00
IUUC-Ath-006974	Arabidopsis thaliana	29.36	4.00e-90	323.00
IUUC-Ago-007890	Ashbya gossypii	26.77	2.00e-69	254.00
IUUC-Acl-008057	Aspergillus clavatus	37.12	4.00e-137	479.00
IUUC-Afl-008547	Aspergillus flavus	36.92	3.00e-118	417.00
IUUC-Afu-008805	Aspergillus fumigatus	33.38	4.00e-109	386.00
IUUC-Ani-009441	Aspergillus nidulans	33.55	9.00e-101	358.00
IUUC-Ang-009720	Aspergillus niger	36.09	2.00e-136	477.00
IUUC-Aor-010111	Aspergillus oryzae	37.52	1.00e-142	498.00
IUUC-Ate-010531	Aspergillus terreus	34.10	2.00e-115	407.00
IUUC-Ame-011470	Astyanax mexicanus	29.25	3.00e-96	344.00
IUUC-Bgr-012183	Blumeria graminis	38.93	2.00e-142	497.00
IUUC-Bta-013179	Bos taurus	30.29	2.00e-105	374.00
IUUC-Bci-013858	Botrytis cinerea	36.71	5.00e-146	509.00
IUUC-Bdi-014904	Brachypodium distachyon	30.02	3.00e-83	301.00
IUUC-Bol-015536	Brassica oleracea	29.51	1.00e-92	332.00
IUUC-Bra-017939	Brassica rapa	30.58	2.00e-94	337.00
IUUC-Cel-018625	Caenorhabditis elegans	27.09	2.00e-63	235.00
IUUC-Cja-019063	Callithrix jacchus	29.97	1.00e-103	369.00
IUUC-Cfa-020976	Canis familiaris	31.13	1.00e-110	392.00
IUUC-Cpo-022265	Cavia porcellus	31.09	2.00e-111	394.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	29.27	5.00e-37	147.00
IUUC-Csa-024177	Chlorocebus sabaeus	30.77	5.00e-96	343.00
IUUC-Cho-024702	Choloepus hoffmanni	30.80	3.00e-64	237.00
IUUC-Cin-025411	Ciona intestinalis	27.52	9.00e-80	289.00
IUUC-Csv-026347	Ciona savignyi	28.26	1.00e-77	282.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	37.10	6.00e-133	466.00
IUUC-Cne-026831	Cryptococcus neoformans	40.22	3.00e-151	526.00
IUUC-Cme-027335	Cyanidioschyzon merolae	26.32	2.00e-36	145.00
IUUC-Dre-027982	Danio rerio	30.39	6.00e-94	336.00
IUUC-Dno-029034	Dasypus novemcinctus	30.62	4.00e-107	380.00
IUUC-Dor-030479	Dipodomys ordii	33.64	9.00e-42	163.00
IUUC-Dse-031467	Dothistroma septosporum	36.04	8.00e-142	495.00
IUUC-Dme-032075	Drosophila melanogaster	30.34	5.00e-91	326.00
IUUC-Ete-032865	Echinops telfairi	32.13	1.00e-63	236.00
IUUC-Eca-034059	Equus caballus	30.41	3.00e-106	377.00
IUUC-Eeu-035304	Erinaceus europaeus	31.85	3.00e-96	344.00
IUUC-Fca-035515	Felis catus	30.40	7.00e-107	379.00
IUUC-Fal-037271	Ficedula albicollis	31.24	6.00e-100	356.00
IUUC-Fox-037745	Fusarium oxysporum	37.93	2.00e-143	501.00
IUUC-Fso-038158	Fusarium solani	38.69	8.00e-146	508.00
IUUC-Gmo-039071	Gadus morhua	29.83	1.00e-89	322.00
IUUC-Ggr-040098	Gaeumannomyces graminis	37.52	2.00e-135	474.00
IUUC-Gga-040635	Gallus gallus	30.37	1.00e-108	385.00
IUUC-Gac-042528	Gasterosteus aculeatus	30.65	1.00e-95	342.00
IUUC-Gma-043614	Glycine max	29.94	6.00e-89	320.00
IUUC-Ggo-044602	Gorilla gorilla	30.48	5.00e-106	376.00
IUUC-Hsa-045959	Homo sapiens	30.48	5.00e-106	376.00
IUUC-Hvu-047563	Hordeum vulgare	31.45	2.00e-80	291.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	30.03	1.00e-107	381.00
IUUC-Kpa-049156	Komagataella pastoris	31.55	1.00e-107	382.00
IUUC-Lch-049648	Latimeria chalumnae	29.95	1.00e-101	362.00
IUUC-Lpe-051523	Leersia perrieri	30.33	4.00e-86	310.00
IUUC-Loc-052072	Lepisosteus oculatus	29.76	1.00e-92	332.00
IUUC-Lma-053216	Leptosphaeria maculans	37.14	7.00e-125	440.00
IUUC-Laf-054327	Loxodonta africana	30.29	5.00e-106	376.00
IUUC-Mcc-055443	Macaca mulatta	30.18	2.00e-105	374.00
IUUC-Meu-056298	Macropus eugenii	30.67	2.00e-70	258.00
IUUC-Mor-057106	Magnaporthe oryzae	38.27	1.00e-144	504.00
IUUC-Mpo-057589	Magnaporthe poae	37.81	2.00e-133	467.00
IUUC-Mtr-058680	Medicago truncatula	30.78	2.00e-98	351.00
IUUC-Mla-058903	Melampsora laricipopulina	48.67	0.00e+00	700.00
IUUC-Mga-059669	Meleagris gallopavo	30.10	5.00e-101	360.00
IUUC-Mvi-060476	Microbotryum violaceum	40.55	1.00e-142	498.00
IUUC-Mmr-060575	Microcebus murinus	30.47	7.00e-108	382.00
IUUC-Mdo-062183	Monodelphis domestica	30.89	1.00e-110	392.00
IUUC-Mmu-063592	Mus musculus	30.58	1.00e-108	385.00
IUUC-Mac-065634	Musa acuminata	27.60	5.00e-83	300.00
IUUC-Mpu-066082	Mustela putorius furo	31.31	1.00e-110	391.00
IUUC-Mlu-067345	Myotis lucifugus	29.82	8.00e-104	369.00
IUUC-Nfi-068558	Neosartorya fischeri	35.64	2.00e-125	441.00
IUUC-Ncr-068960	Neurospora crassa	37.20	1.00e-131	461.00
IUUC-Nle-070173	Nomascus leucogenys	31.21	2.00e-109	388.00
IUUC-Opr-070556	Ochotona princeps	30.62	2.00e-109	388.00
IUUC-Ont-071502	Oreochromis niloticus	30.56	2.00e-98	351.00
IUUC-Oan-072959	Ornithorhynchus anatinus	27.93	4.00e-26	108.00
IUUC-Ocu-074861	Oryctolagus cuniculus	31.09	4.00e-110	390.00
IUUC-Oba-075109	Oryza barthii	30.67	3.00e-89	321.00
IUUC-Obr-076292	Oryza brachyantha	30.84	6.00e-85	306.00
IUUC-Ogl-077065	Oryza glaberrima	30.87	2.00e-94	338.00
IUUC-Ogu-078776	Oryza glumaepatula	31.03	1.00e-91	328.00
IUUC-Oin-080048	Oryza indica	30.75	8.00e-93	332.00
IUUC-Olo-080711	Oryza longistaminata	33.91	4.00e-65	240.00
IUUC-Ome-081506	Oryza meridionalis	30.53	6.00e-81	293.00
IUUC-Oni-082320	Oryza nivara	30.20	8.00e-88	316.00
IUUC-Opu-083801	Oryza punctata	30.13	2.00e-83	301.00
IUUC-Oru-085139	Oryza rufipogon	30.31	6.00e-87	313.00
IUUC-Osa-085713	Oryza sativa	30.99	7.00e-96	342.00
IUUC-Ola-086951	Oryzias latipes	29.54	2.00e-91	328.00
IUUC-Olu-087822	Ostreococcus lucimarinus	29.97	4.00e-77	280.00
IUUC-Oga-088625	Otolemur garnettii	29.84	2.00e-106	378.00
IUUC-Oar-089995	Ovis aries	30.18	6.00e-104	369.00
IUUC-Ptr-090640	Pan troglodytes	30.82	7.00e-110	389.00
IUUC-Pan-091974	Papio anubis	29.74	1.00e-104	372.00
IUUC-Psi-093957	Pelodiscus sinensis	30.45	5.00e-108	383.00
IUUC-Pma-094242	Petromyzon marinus	28.15	7.00e-42	162.00
IUUC-Pno-094835	Phaeosphaeria nodorum	36.92	6.00e-106	376.00
IUUC-Ppa-095901	Physcomitrella patens	30.20	1.00e-97	348.00
IUUC-Pfo-097148	Poecilia formosa	30.30	5.00e-99	353.00
IUUC-Pab-098672	Pongo abelii	27.11	4.00e-81	294.00
IUUC-Pop-098855	Populus trichocarpa	29.90	1.00e-86	312.00
IUUC-Pca-100738	Procavia capensis	32.26	9.00e-78	283.00
IUUC-Ppe-101315	Prunus persica	28.84	2.00e-87	315.00
IUUC-Pva-102154	Pteropus vampyrus	30.02	5.00e-103	366.00
IUUC-Pgr-103343	Puccinia graminis	80.18	0.00e+00	1011.00
IUUC-Pte-104306	Pyrenophora teres	36.87	9.00e-116	409.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	36.93	1.00e-119	422.00
IUUC-Rno-105801	Rattus norvegicus	30.81	5.00e-108	383.00
IUUC-Sce-106304	Saccharomyces cerevisiae	26.28	2.00e-66	245.00
IUUC-Sha-107635	Sarcophilus harrisii	31.58	1.00e-112	398.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	34.95	8.00e-118	415.00
IUUC-Spo-108144	Schizosaccharomyces pombe	33.82	1.00e-118	418.00
IUUC-Smo-108703	Selaginella moellendorffii	30.81	6.00e-89	319.00
IUUC-Sit-110728	Setaria italica	31.01	8.00e-94	336.00
IUUC-Sly-111523	Solanum lycopersicum	30.20	2.00e-102	364.00
IUUC-Sar-113733	Sorex araneus	30.42	5.00e-35	140.00
IUUC-Sbi-114419	Sorghum bicolor	29.53	8.00e-88	316.00
IUUC-Sre-115225	Sporisorium reilianum	39.19	2.00e-144	504.00
IUUC-Ssc-115686	Sus scrofa	29.81	1.00e-106	379.00
IUUC-Tgu-117346	Taeniopygia guttata	30.11	3.00e-101	360.00
IUUC-Tru-118350	Takifugu rubripes	28.27	5.00e-88	317.00
IUUC-Tsy-119278	Tarsius syrichta	27.11	2.00e-72	265.00
IUUC-Tni-120658	Tetraodon nigroviridis	29.04	3.00e-87	314.00
IUUC-Tca-121585	Theobroma cacao	30.27	4.00e-84	303.00
IUUC-Tre-122043	Trichoderma reesei	38.55	3.00e-141	493.00
IUUC-Tvi-122303	Trichoderma virens	38.12	3.00e-140	490.00
IUUC-Tae-123798	Triticum aestivum	29.38	1.00e-85	309.00
IUUC-Tur-126732	Triticum urartu	28.13	1.00e-75	275.00
IUUC-Tme-126909	Tuber melanosporum	37.73	2.00e-138	484.00
IUUC-Tbe-127261	Tupaia belangeri	30.44	2.00e-48	185.00
IUUC-Ttr-129119	Tursiops truncatus	30.68	2.00e-48	185.00
IUUC-Uma-129599	Ustilago maydis	38.00	2.00e-144	504.00
IUUC-Vda-129688	Verticillium dahliae	38.08	5.00e-136	476.00
IUUC-Vpa-130170	Vicugna pacos	24.82	4.00e-34	137.00
IUUC-Vvi-131116	Vitis vinifera	29.62	6.00e-85	306.00
IUUC-Xtr-131953	Xenopus tropicalis	30.80	6.00e-100	356.00
IUUC-Xma-133837	Xiphophorus maculatus	30.18	3.00e-98	351.00
IUUC-Yli-134510	Yarrowia lipolytica	35.19	2.00e-110	391.00
IUUC-Zma-135786	Zea mays	29.51	5.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence