iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000012546.1	ENSONIT00000015810.1	ENSONIP00000015795.1
ENSONIG00000012546.1	ENSONIT00000015811.1	ENSONIP00000015796.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.40e-27	92.9	728	765
UBD/Beta-Prp	2.40e-41	142.3	632	890

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.fsd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt+ +  l  + + ++++sGs D+t++ WDlr   +++
   Q: 728  GHTGHILTLYtW-GgWMIASGSQDKTVRFWDLRVPSCVR 765
           799999999669.44*****************9888875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgk....ilvtgse.Drtikvwdlstg 84
           ++hhk+ i+cv++s  ++llatgs d+ +kv  +   ++       ++s h+++++++ f +  +    il++++  D +i+  d + g
   Q: 632  NKHHKGSIYCVAWSHCGQLLATGSNDKYVKVLPFNADTCnatgpDLEFSMHDGTIRDLAFMEGPEsggsILISAGAgDCNIYTTDCQRG 720
           58*****************************99999888888887899************887666677888765516788888***** PP
   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           + +h+l+gh+  +l+l     g  ++sGs+d+t+r wdl+  +c++    tl g+ ++v +v+v+p+g+ll++G  D+t++l+d++ g+
   Q: 721  QGLHALSGHTGHILTLYTWG-GWMIASGSQDKTVRFWDLRVPSCVRVvgtTLHGTGSAVASVAVDPSGRLLATGQEDSTCMLYDIRGGR 808
           ***************98888.8***********************99999*************************************** PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq...tgecvrtlng.htdnvksvrfspnderlvsgssDgsiriW 249
           +++t +  h ++++s+ f++   +l++gs+d+++++ dlq   t+   +t+ g h d v + r +p+d  +vs s+D+++ +W
   Q: 809  IVQTYRP-HSSDIRSVRFSPGAHHLLTGSYDNRIIISDLQgdlTKPLPQTVAGeHWDKVIQCRWHPHDRTFVSSSADRTVILW 890
           ******9.********************************9997777777777699************************999 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTAEETINIK EAEVTKLILD FLNSRKLHIS MLALEKESGV INGLYSDDML FLRQLILDGQ 60
WEEVMQFIQP LEGMDKFDKK RFRYIIFKQK FLEALCVNNA MSAAEDPLNL EITMQEAVKC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGCAG AGGAGACGAT CAACATAAAG GAGGCTGAGG TGACCAAGCT GATCCTGGAC 60
TTTCTCAACT CCAGGAAGCT GCACATTAGC ATGCTGGCCC TGGAGAAGGA AAGCGGTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR006595--CTLH_C
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018667	Caenorhabditis elegans	48.96	8.00e-96	345.00
IUUC-Cin-025112	Ciona intestinalis	44.55	8.00e-74	270.00
IUUC-Dme-032040	Drosophila melanogaster	52.57	1.00e-101	363.00
IUUC-Gac-041429	Gasterosteus aculeatus	84.73	0.00e+00	1448.00
IUUC-Ola-087341	Oryzias latipes	83.56	0.00e+00	1425.00
IUUC-Pfo-096439	Poecilia formosa	87.81	0.00e+00	1514.00
IUUC-Tru-117591	Takifugu rubripes	84.07	0.00e+00	1404.00
IUUC-Tni-120018	Tetraodon nigroviridis	79.72	0.00e+00	1435.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence