iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089108

Ensembl Protein ID

ENSOGAP00000020353.1

UniProt Accession

H0XW60; H0XW60_OTOGA

Genbank Protein ID

ENSOGAP00000020353

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03161062

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000026524.1	ENSOGAT00000026542.1	ENSOGAP00000020353.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-35	119.3	251	282
UBD/Beta-Prp	3.90e-58	197.0	74	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           H ++++++++ +d t+l+s+s+D+t k+WD++
   Q: 251  HDGGIYAISWsPDsTHLLSASGDKTSKIWDVS 282
           99*********999****************86 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 74   EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 162
           556666678*************************998777742334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +s+ ++l +Gs+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d k+g+ +  l  +++
   Q: 163  HNKVINSVDIKQSRpYRLTTGSDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKSGEKVCALggSKA 250
           ************998*****************9999998.99********************************************888 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
           h++ +y +s+++++++l+s+s d+t k+wd++ +++v t+   +
   Q: 251  HDGGIYAISWSPDSTHLLSASGDKTSKIWDVSMNSVVSTFPMGS 294
           ************************************99997544 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

RAGPGGSGLA RRSNKWARMP YEIKKVFASL PQVERGVSKI IGGDPKGNNF LYTNGKCVIL 60
RNIDNPAVAD IYTEHAHQVV VAKYAPSGFY IASGDVSGKL RIWDTTQKEH LLKYEYQPFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGTCCT CAGCGGCAGC GCGCAGGGCA GGCGTGAGCT GGCCTGAGAG CCCCGGCCTC 60
GCACCGCCCC CTGCACGCCC GGCACGCCCG GCGCCGCCTT CCGGCCCAGT CCCCGGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	34.33	4.00e-79	288.00
IUUC-Aml-002368	Ailuropoda melanoleuca	92.69	0.00e+00	1175.00
IUUC-Atr-003160	Amborella trichopoda	36.83	5.00e-113	401.00
IUUC-Apl-004012	Anas platyrhynchos	85.69	0.00e+00	1086.00
IUUC-Aca-004707	Anolis carolinensis	82.03	0.00e+00	1045.00
IUUC-Aly-006465	Arabidopsis lyrata	37.26	2.00e-108	386.00
IUUC-Ath-006740	Arabidopsis thaliana	36.45	2.00e-107	382.00
IUUC-Ago-007920	Ashbya gossypii	27.34	5.00e-71	262.00
IUUC-Acl-008262	Aspergillus clavatus	36.45	9.00e-106	377.00
IUUC-Afl-008471	Aspergillus flavus	30.50	2.00e-67	249.00
IUUC-Afu-008989	Aspergillus fumigatus	38.37	2.00e-95	342.00
IUUC-Ani-009167	Aspergillus nidulans	37.89	2.00e-115	409.00
IUUC-Ang-009595	Aspergillus niger	37.35	8.00e-102	364.00
IUUC-Aor-009908	Aspergillus oryzae	36.56	8.00e-102	364.00
IUUC-Ate-010580	Aspergillus terreus	37.38	5.00e-107	383.00
IUUC-Ame-011269	Astyanax mexicanus	60.00	2.00e-132	466.00
IUUC-Bgr-011996	Blumeria graminis	34.03	3.00e-105	375.00
IUUC-Bta-013278	Bos taurus	94.60	0.00e+00	1202.00
IUUC-Bci-013925	Botrytis cinerea	34.89	1.00e-104	374.00
IUUC-Bdi-014659	Brachypodium distachyon	34.63	1.00e-100	360.00
IUUC-Bol-016043	Brassica oleracea	34.85	6.00e-104	371.00
IUUC-Bra-017139	Brassica rapa	35.86	2.00e-106	379.00
IUUC-Cel-018417	Caenorhabditis elegans	41.05	7.00e-122	431.00
IUUC-Cja-019952	Callithrix jacchus	95.13	0.00e+00	1174.00
IUUC-Cfa-020225	Canis familiaris	95.09	0.00e+00	1186.00
IUUC-Cpo-021900	Cavia porcellus	93.89	0.00e+00	1167.00
IUUC-Csa-023028	Chlorocebus sabaeus	95.74	0.00e+00	1166.00
IUUC-Cho-025030	Choloepus hoffmanni	67.60	0.00e+00	754.00
IUUC-Cin-025152	Ciona intestinalis	55.21	4.00e-81	294.00
IUUC-Csv-025986	Ciona savignyi	36.60	1.00e-90	326.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.13	4.00e-110	391.00
IUUC-Cne-026814	Cryptococcus neoformans	34.29	4.00e-97	348.00
IUUC-Dre-027498	Danio rerio	80.51	9.00e-96	342.00
IUUC-Dno-029383	Dasypus novemcinctus	93.62	0.00e+00	1140.00
IUUC-Dor-030633	Dipodomys ordii	93.10	0.00e+00	1092.00
IUUC-Dse-031526	Dothistroma septosporum	38.08	2.00e-115	409.00
IUUC-Dme-031597	Drosophila melanogaster	48.52	3.00e-168	584.00
IUUC-Ete-032780	Echinops telfairi	83.80	0.00e+00	1046.00
IUUC-Eca-034306	Equus caballus	93.39	0.00e+00	1146.00
IUUC-Eeu-034531	Erinaceus europaeus	73.01	9.00e-136	476.00
IUUC-Fca-036301	Felis catus	95.87	0.00e+00	1203.00
IUUC-Fal-037361	Ficedula albicollis	87.03	0.00e+00	1127.00
IUUC-Fox-037924	Fusarium oxysporum	35.18	2.00e-99	356.00
IUUC-Fso-038199	Fusarium solani	34.52	2.00e-96	346.00
IUUC-Gmo-039238	Gadus morhua	71.73	0.00e+00	887.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.03	3.00e-94	339.00
IUUC-Gga-040235	Gallus gallus	88.40	0.00e+00	1108.00
IUUC-Gac-042363	Gasterosteus aculeatus	71.08	0.00e+00	917.00
IUUC-Gma-044189	Glycine max	36.20	3.00e-109	389.00
IUUC-Ggo-044632	Gorilla gorilla	94.45	0.00e+00	1147.00
IUUC-Hsa-045792	Homo sapiens	95.91	0.00e+00	1195.00
IUUC-Hvu-047517	Hordeum vulgare	34.09	2.00e-104	372.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	95.71	0.00e+00	1178.00
IUUC-Kpa-049183	Komagataella pastoris	33.12	1.00e-85	310.00
IUUC-Lch-050428	Latimeria chalumnae	75.97	0.00e+00	1009.00
IUUC-Lpe-051306	Leersia perrieri	35.33	1.00e-106	380.00
IUUC-Loc-052096	Lepisosteus oculatus	71.11	0.00e+00	898.00
IUUC-Lma-053313	Leptosphaeria maculans	38.96	3.00e-115	411.00
IUUC-Laf-054060	Loxodonta africana	91.23	0.00e+00	1146.00
IUUC-Mcc-055619	Macaca mulatta	94.45	0.00e+00	1146.00
IUUC-Meu-056689	Macropus eugenii	77.67	0.00e+00	637.00
IUUC-Mor-056940	Magnaporthe oryzae	35.05	4.00e-96	345.00
IUUC-Mpo-057557	Magnaporthe poae	28.21	8.00e-56	211.00
IUUC-Mtr-057922	Medicago truncatula	35.33	9.00e-107	380.00
IUUC-Mla-059103	Melampsora laricipopulina	32.58	8.00e-76	278.00
IUUC-Mga-060150	Meleagris gallopavo	88.01	0.00e+00	1093.00
IUUC-Mvi-060448	Microbotryum violaceum	30.82	2.00e-73	270.00
IUUC-Mmr-061226	Microcebus murinus	95.09	0.00e+00	1170.00
IUUC-Mdo-062674	Monodelphis domestica	91.00	0.00e+00	1144.00
IUUC-Mmu-064170	Mus musculus	94.27	0.00e+00	1178.00
IUUC-Mac-065124	Musa acuminata	36.98	5.00e-111	394.00
IUUC-Mpu-066001	Mustela putorius furo	92.11	0.00e+00	1168.00
IUUC-Mlu-067253	Myotis lucifugus	94.51	0.00e+00	1182.00
IUUC-Nfi-068550	Neosartorya fischeri	38.24	3.00e-110	392.00
IUUC-Ncr-068948	Neurospora crassa	36.36	6.00e-113	401.00
IUUC-Nle-070115	Nomascus leucogenys	91.74	0.00e+00	1074.00
IUUC-Opr-070254	Ochotona princeps	92.23	0.00e+00	1113.00
IUUC-Ont-071666	Oreochromis niloticus	74.47	0.00e+00	948.00
IUUC-Oan-073594	Ornithorhynchus anatinus	90.53	3.00e-166	577.00
IUUC-Ocu-074824	Oryctolagus cuniculus	93.13	0.00e+00	1132.00
IUUC-Oba-075010	Oryza barthii	35.71	8.00e-108	384.00
IUUC-Obr-076364	Oryza brachyantha	36.25	6.00e-109	388.00
IUUC-Ogl-077019	Oryza glaberrima	35.71	8.00e-108	384.00
IUUC-Ogu-078496	Oryza glumaepatula	35.71	8.00e-108	384.00
IUUC-Oin-080116	Oryza indica	35.88	3.00e-108	385.00
IUUC-Olo-080290	Oryza longistaminata	35.71	2.00e-107	383.00
IUUC-Ome-081969	Oryza meridionalis	35.71	1.00e-107	384.00
IUUC-Oni-082075	Oryza nivara	35.71	6.00e-108	384.00
IUUC-Opu-083959	Oryza punctata	35.92	8.00e-108	384.00
IUUC-Oru-084711	Oryza rufipogon	35.71	8.00e-108	384.00
IUUC-Osa-085958	Oryza sativa	35.88	3.00e-108	385.00
IUUC-Ola-086968	Oryzias latipes	75.65	0.00e+00	966.00
IUUC-Oar-089986	Ovis aries	88.94	0.00e+00	1108.00
IUUC-Ptr-091281	Pan troglodytes	96.03	0.00e+00	1183.00
IUUC-Pan-092585	Papio anubis	95.91	0.00e+00	1169.00
IUUC-Psi-093811	Pelodiscus sinensis	85.83	0.00e+00	1114.00
IUUC-Pma-094396	Petromyzon marinus	71.06	0.00e+00	915.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.84	2.00e-107	382.00
IUUC-Ppa-095876	Physcomitrella patens	36.04	3.00e-109	389.00
IUUC-Pfo-096973	Poecilia formosa	74.63	0.00e+00	986.00
IUUC-Pab-098391	Pongo abelii	95.58	0.00e+00	1170.00
IUUC-Pop-098850	Populus trichocarpa	36.08	3.00e-109	389.00
IUUC-Pca-100257	Procavia capensis	61.13	1.00e-93	337.00
IUUC-Ppe-101578	Prunus persica	37.28	3.00e-112	399.00
IUUC-Pva-102872	Pteropus vampyrus	89.69	0.00e+00	1137.00
IUUC-Pgr-103593	Puccinia graminis	32.45	2.00e-78	286.00
IUUC-Pte-104365	Pyrenophora teres	39.00	1.00e-110	393.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.68	3.00e-113	402.00
IUUC-Rno-105737	Rattus norvegicus	94.93	0.00e+00	1211.00
IUUC-Sce-106383	Saccharomyces cerevisiae	29.61	4.00e-68	252.00
IUUC-Sha-107084	Sarcophilus harrisii	89.03	0.00e+00	1010.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	34.75	3.00e-109	389.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.22	6.00e-94	338.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	34.89	6.00e-105	374.00
IUUC-Smo-109255	Selaginella moellendorffii	33.77	3.00e-97	349.00
IUUC-Sit-109962	Setaria italica	36.63	1.00e-109	390.00
IUUC-Sly-110897	Solanum lycopersicum	37.76	1.00e-113	403.00
IUUC-Stu-111971	Solanum tuberosum	37.76	4.00e-113	402.00
IUUC-Sar-113415	Sorex araneus	72.32	3.00e-109	388.00
IUUC-Sbi-114857	Sorghum bicolor	36.14	2.00e-107	382.00
IUUC-Sre-114900	Sporisorium reilianum	33.01	5.00e-90	325.00
IUUC-Tgu-117256	Taeniopygia guttata	87.31	0.00e+00	1120.00
IUUC-Tru-117871	Takifugu rubripes	69.84	0.00e+00	886.00
IUUC-Tsy-119172	Tarsius syrichta	97.08	2.00e-139	489.00
IUUC-Tni-120339	Tetraodon nigroviridis	69.00	0.00e+00	917.00
IUUC-Tca-121609	Theobroma cacao	36.88	1.00e-110	393.00
IUUC-Tre-122076	Trichoderma reesei	35.86	8.00e-94	337.00
IUUC-Tvi-122528	Trichoderma virens	34.68	1.00e-95	343.00
IUUC-Tae-123530	Triticum aestivum	34.47	8.00e-106	377.00
IUUC-Tur-126845	Triticum urartu	33.87	2.00e-77	283.00
IUUC-Tme-127217	Tuber melanosporum	34.49	9.00e-103	367.00
IUUC-Tbe-127526	Tupaia belangeri	93.28	0.00e+00	1167.00
IUUC-Ttr-128898	Tursiops truncatus	87.56	0.00e+00	1102.00
IUUC-Uma-129631	Ustilago maydis	31.66	2.00e-92	332.00
IUUC-Vda-129732	Verticillium dahliae	34.39	5.00e-90	325.00
IUUC-Vvi-131217	Vitis vinifera	37.58	5.00e-111	394.00
IUUC-Xtr-132860	Xenopus tropicalis	74.35	0.00e+00	952.00
IUUC-Xma-133830	Xiphophorus maculatus	74.63	0.00e+00	986.00
IUUC-Yli-134335	Yarrowia lipolytica	32.74	2.00e-74	273.00
IUUC-Zma-135907	Zea mays	36.30	3.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence