iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117115

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01033574

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000012493.1	ENSTGUT00000013008.1	ENSTGUP00000012861.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-59	201.0	5	320

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl Nlg +C +NS+LQ+ ++   +++ l +    +++ + p ++ +++  ++  l+e+++ +k kav p++l  +l++  +e   + q+
   Q: 5    GLYNLGQSCCLNSLLQVFLMNIHFTRILRR---ITVPSS-PAQRRNNVPYQMLLLLEKMQCGKCKAVGPTDLACCLSEHRVE--LFVQH 87
           9***************************99...555544.568889******************************977766..89*** PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da  ++  l + l++++                          kk +  + +sdl+ + +++++ c++c  + + ++++l+l+lpv + 
   Q: 88   DAAQLFLTLWNLLKKQM--------------------------KKPELVEELSDLYTICIQEHLACQKCSFEVKNNSTMLTLPLPVLDA 150
           *****************..........................4566667799************************************ PP
   S: 180  eetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts. 267
           ++  +++l+dcL+ f+ +eel+g+n+++c++c +k++  +++kl +lP++L lhLkRf+f+++ ++ +k++ ++ fp+eLdl++ +t+ 
   Q: 151  NSHRLKTLEDCLQYFFHPEELTGQNMCFCQQCGRKTTFLQSMKLVHLPQTLALHLKRFCFERS-SRTQKLSLHLPFPQELDLREILTEs 238
           ************************************************************887.8889***************977773 PP
   S: 268  ...peekqke....kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......staYvlfYkrr 338
               +    +    + ++eL+avv HsG +s+GHY+ay+++ ++ kW++f+Ds+V +v++++v+ + g       +taY+lfY+++
   Q: 239  qcqAD----DsekgTWQFELFAVVAHSGLSSCGHYCAYIRSlTDCKWYCFNDSEVCQVSWDDVKCTYGhsnlcwrETAYLLFYMKK 320
           33322....23444999************************55566*******************888***************985 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

TEAIGLYNLG QSCCLNSLLQ VFLMNIHFTR ILRRITVPSS PAQRRNNVPY QMLLLLEKMQ 60
CGKCKAVGPT DLACCLSEHR VELFVQHDAA QLFLTLWNLL KKQMKKPELV EELSDLYTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGAAGCTA TTGGACTGTA CAACCTTGGG CAGAGCTGCT GTCTGAACTC TCTGCTCCAA 60
GTGTTCCTCA TGAACATACA CTTCACAAGG ATCCTCCGAA GGTACCTCCT GTTTGAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	54.43	6.00e-96	343.00
IUUC-Apl-004006	Anas platyrhynchos	76.09	4.00e-146	510.00
IUUC-Aca-005088	Anolis carolinensis	55.80	7.00e-94	337.00
IUUC-Ame-010606	Astyanax mexicanus	36.08	6.00e-45	174.00
IUUC-Bta-013036	Bos taurus	53.16	1.00e-96	345.00
IUUC-Cja-019052	Callithrix jacchus	51.41	1.00e-88	319.00
IUUC-Cfa-020554	Canis familiaris	55.70	8.00e-103	366.00
IUUC-Cpo-022421	Cavia porcellus	55.17	2.00e-100	358.00
IUUC-Csa-023737	Chlorocebus sabaeus	51.74	3.00e-58	217.00
IUUC-Cho-024807	Choloepus hoffmanni	45.36	2.00e-40	159.00
IUUC-Dre-027408	Danio rerio	35.83	1.00e-44	172.00
IUUC-Dno-029813	Dasypus novemcinctus	46.20	8.00e-71	259.00
IUUC-Dor-030532	Dipodomys ordii	54.89	1.00e-98	352.00
IUUC-Ete-032254	Echinops telfairi	52.50	8.00e-96	343.00
IUUC-Eca-033482	Equus caballus	54.43	5.00e-101	360.00
IUUC-Eeu-034451	Erinaceus europaeus	49.52	1.00e-55	208.00
IUUC-Fca-036313	Felis catus	56.92	4.00e-103	367.00
IUUC-Fal-037216	Ficedula albicollis	88.24	6.00e-171	592.00
IUUC-Gmo-038649	Gadus morhua	33.54	7.00e-49	187.00
IUUC-Gga-041082	Gallus gallus	73.68	2.00e-134	471.00
IUUC-Gac-042439	Gasterosteus aculeatus	37.54	3.00e-50	191.00
IUUC-Ggo-044957	Gorilla gorilla	52.21	8.00e-81	292.00
IUUC-Hsa-046381	Homo sapiens	56.01	4.00e-103	367.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	53.80	5.00e-99	353.00
IUUC-Loc-052688	Lepisosteus oculatus	37.30	2.00e-50	192.00
IUUC-Laf-054109	Loxodonta africana	56.92	4.00e-104	370.00
IUUC-Mcc-054814	Macaca mulatta	55.06	4.00e-102	364.00
IUUC-Meu-056253	Macropus eugenii	54.36	1.00e-79	288.00
IUUC-Mmr-061613	Microcebus murinus	55.70	4.00e-102	363.00
IUUC-Mdo-061890	Monodelphis domestica	53.29	8.00e-95	339.00
IUUC-Mmu-064329	Mus musculus	54.11	8.00e-93	333.00
IUUC-Mpu-066342	Mustela putorius furo	55.70	5.00e-103	367.00
IUUC-Mlu-067010	Myotis lucifugus	55.35	5.00e-100	357.00
IUUC-Nle-069148	Nomascus leucogenys	55.70	5.00e-103	367.00
IUUC-Opr-070988	Ochotona princeps	50.32	2.00e-44	172.00
IUUC-Ont-072039	Oreochromis niloticus	35.87	2.00e-48	185.00
IUUC-Oan-073740	Ornithorhynchus anatinus	47.48	2.00e-54	205.00
IUUC-Ocu-074498	Oryctolagus cuniculus	54.75	5.00e-94	337.00
IUUC-Ola-086753	Oryzias latipes	38.32	2.00e-50	192.00
IUUC-Oga-088497	Otolemur garnettii	55.41	9.00e-101	359.00
IUUC-Oar-089505	Ovis aries	55.66	3.00e-99	354.00
IUUC-Ptr-091656	Pan troglodytes	56.33	8.00e-105	373.00
IUUC-Pan-092498	Papio anubis	55.06	3.00e-102	364.00
IUUC-Psi-093409	Pelodiscus sinensis	64.24	4.00e-123	433.00
IUUC-Pfo-096507	Poecilia formosa	35.71	6.00e-47	180.00
IUUC-Pab-097828	Pongo abelii	54.86	2.00e-100	358.00
IUUC-Pca-100299	Procavia capensis	58.47	4.00e-59	221.00
IUUC-Pva-102972	Pteropus vampyrus	53.00	1.00e-94	339.00
IUUC-Rno-105738	Rattus norvegicus	52.85	9.00e-93	333.00
IUUC-Sha-107309	Sarcophilus harrisii	51.00	3.00e-85	307.00
IUUC-Sar-112983	Sorex araneus	53.31	8.00e-80	290.00
IUUC-Ssc-116049	Sus scrofa	54.89	1.00e-99	355.00
IUUC-Tru-118022	Takifugu rubripes	35.56	1.00e-45	176.00
IUUC-Tsy-118986	Tarsius syrichta	57.26	1.00e-34	139.00
IUUC-Tni-120306	Tetraodon nigroviridis	35.87	7.00e-46	177.00
IUUC-Tbe-127768	Tupaia belangeri	48.28	7.00e-56	210.00
IUUC-Ttr-128686	Tursiops truncatus	54.09	2.00e-96	345.00
IUUC-Xtr-132032	Xenopus tropicalis	43.93	2.00e-71	261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence