iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017171.3	ENSMMUT00000024141.3	ENSMMUP00000022588.3
ENSMMUG00000017171.3	ENSMMUT00000024140.3	ENSMMUP00000022587.3
ENSMMUG00000017171.3	ENSMMUT00000011385.3	ENSMMUP00000010669.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.70e-19	69.6	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.70e-08	31.4	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 51   DVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++r+A+l+d+++L ++ +++ilk+F
   Q: 150  ENILDVYRLAELFDLSRLTEQLDTYILKNF 179
           8***************************** PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAEEQEFTQL CKLPAQPSHP HCVNNTYRSA QHSQALLRGL LALRDSGILF DVVLVVEGRH 60
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCCTCCC TCCTGCTGCG AGCGCGGCCT CGGCTGGCGG CGGCACCAGG TCAGCTGCGA 60
GGCGTGGGCC GGGCGGGTCG CGCGGCGGCG AACGCGGGGG GCGGGCGGCA AGCAGGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	97.47	0.00e+00	1021.00
IUUC-Apl-004081	Anas platyrhynchos	79.96	0.00e+00	843.00
IUUC-Aca-005015	Anolis carolinensis	65.12	0.00e+00	709.00
IUUC-Ame-011712	Astyanax mexicanus	59.76	3.00e-173	602.00
IUUC-Bta-012594	Bos taurus	93.58	0.00e+00	982.00
IUUC-Cja-019752	Callithrix jacchus	98.44	0.00e+00	792.00
IUUC-Cfa-020884	Canis familiaris	97.86	0.00e+00	1024.00
IUUC-Cpo-021711	Cavia porcellus	96.89	0.00e+00	1018.00
IUUC-Csa-023211	Chlorocebus sabaeus	99.81	0.00e+00	1041.00
IUUC-Dre-028395	Danio rerio	61.65	0.00e+00	627.00
IUUC-Dno-030096	Dasypus novemcinctus	93.58	0.00e+00	979.00
IUUC-Dor-030709	Dipodomys ordii	95.95	0.00e+00	706.00
IUUC-Eca-033388	Equus caballus	97.67	0.00e+00	1021.00
IUUC-Eeu-034616	Erinaceus europaeus	84.24	0.00e+00	863.00
IUUC-Fca-035815	Felis catus	97.67	0.00e+00	1021.00
IUUC-Fal-037311	Ficedula albicollis	82.48	0.00e+00	821.00
IUUC-Gmo-039571	Gadus morhua	47.80	3.00e-131	462.00
IUUC-Gga-040992	Gallus gallus	79.77	0.00e+00	843.00
IUUC-Gac-042041	Gasterosteus aculeatus	57.67	1.00e-164	573.00
IUUC-Ggo-045141	Gorilla gorilla	92.41	0.00e+00	961.00
IUUC-Hsa-045984	Homo sapiens	99.61	0.00e+00	1038.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	97.86	0.00e+00	1025.00
IUUC-Lch-049700	Latimeria chalumnae	57.71	1.00e-171	596.00
IUUC-Loc-052141	Lepisosteus oculatus	63.41	0.00e+00	673.00
IUUC-Laf-053487	Loxodonta africana	95.65	0.00e+00	982.00
IUUC-Meu-055937	Macropus eugenii	73.54	0.00e+00	760.00
IUUC-Mga-059953	Meleagris gallopavo	79.77	0.00e+00	843.00
IUUC-Mmr-061743	Microcebus murinus	97.08	0.00e+00	1009.00
IUUC-Mdo-062328	Monodelphis domestica	83.66	0.00e+00	883.00
IUUC-Mmu-063979	Mus musculus	94.55	0.00e+00	993.00
IUUC-Mpu-066750	Mustela putorius furo	97.86	0.00e+00	1022.00
IUUC-Mlu-066960	Myotis lucifugus	96.11	0.00e+00	1003.00
IUUC-Nle-069690	Nomascus leucogenys	99.54	0.00e+00	903.00
IUUC-Opr-071059	Ochotona princeps	87.96	0.00e+00	894.00
IUUC-Ont-072004	Oreochromis niloticus	59.80	2.00e-165	575.00
IUUC-Oan-073172	Ornithorhynchus anatinus	61.35	1.00e-175	609.00
IUUC-Ola-086599	Oryzias latipes	58.45	3.00e-171	595.00
IUUC-Oga-087980	Otolemur garnettii	96.50	0.00e+00	1004.00
IUUC-Oar-089956	Ovis aries	79.75	0.00e+00	723.00
IUUC-Ptr-090598	Pan troglodytes	99.54	0.00e+00	907.00
IUUC-Pan-092387	Papio anubis	99.63	0.00e+00	1129.00
IUUC-Psi-093484	Pelodiscus sinensis	80.93	0.00e+00	864.00
IUUC-Pma-094224	Petromyzon marinus	50.60	5.00e-143	501.00
IUUC-Pfo-096149	Poecilia formosa	60.21	4.00e-173	601.00
IUUC-Pab-098097	Pongo abelii	99.42	0.00e+00	1038.00
IUUC-Pca-100118	Procavia capensis	95.41	0.00e+00	701.00
IUUC-Pva-103174	Pteropus vampyrus	98.83	1.00e-89	323.00
IUUC-Rno-105350	Rattus norvegicus	94.92	0.00e+00	996.00
IUUC-Sha-106817	Sarcophilus harrisii	86.01	5.00e-73	268.00
IUUC-Sar-113490	Sorex araneus	96.21	0.00e+00	648.00
IUUC-Ssc-115827	Sus scrofa	95.14	0.00e+00	998.00
IUUC-Tgu-116748	Taeniopygia guttata	82.82	0.00e+00	834.00
IUUC-Tru-118644	Takifugu rubripes	58.73	1.00e-170	593.00
IUUC-Tsy-118888	Tarsius syrichta	90.41	0.00e+00	802.00
IUUC-Tni-120060	Tetraodon nigroviridis	54.94	3.00e-146	512.00
IUUC-Ttr-129183	Tursiops truncatus	94.52	0.00e+00	865.00
IUUC-Xtr-132780	Xenopus tropicalis	70.57	0.00e+00	742.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence