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Tag Content
UUCD2 ID IUUC-Xtr-132949
UUCD1 version UUC-XeT-01087
Ensembl Protein ID ENSXETP00000032749.3
UniProt Accession F7DC76; F7DC76_XENTR
Genbank Protein ID ENSXETP00000032749
Protein Name Ubiquitin-specific peptidase 37
Genbank Nucleotide ID AAMC01028420
Gene Name usp37
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000014977.3 ENSXETT00000032749.3 ENSXETP00000032749.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.60e-81 274.3 341 959
UBD/Alpha-Helix/UIM 3.40e-06 26.7 837 854
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L+++++++++ll+   + ++ +  k p+++l++ +++l+++    + + k+   +++++a++++ae+fsgy
   Q: 341  QGFSNLGNTCYMNAILQSLFSLQPFAHDLLK---QGIPYR--KIPTNALIRRFAHLLAKKDicSPEVKKDLLKKVKSAISATAERFSGY 424
           69*****************************...999988..68*************9987779999999******************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +q+Da+Efl+++ldql+e++ k +++ k+e+++ d+    + +++  ++ ++++++ +F+++++++i+c+ c+++ +++e+f+dls+++
   Q: 425  MQNDAHEFLSQCLDQLKEDMGKLNKTWKTELSSGDDVPGVKANDDLSTRIYTCPVTCNFEFEVQHSIICKICGETVNKREQFNDLSIDL 513
           ********************886666667777778888888899********************************************* PP
   S: 177  pgkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
           p++++ +++ s+qd+L+ f++ e le    y cekc +k+ a+ ++k+++lP++LilhLkR+sf+   + ++k+ ++v +p+ L+ls++
   Q: 514  PRRKKPSPSrSIQDSLDLFFRLEDLE----YACEKCSGKS-ATVMHKFSRLPRILILHLKRYSFNVILSLNNKVGQQVVIPRYLTLSSH 597
           ***99987669**************9....********99.9*********************************************** PP
   S: 265  cts...................................................................................... 267
           ct+                                                                                      
   Q: 598  CTEstrtplslgwnaqtalnarplklsqmvnsctmststplrkqmfkaanslpvcldsesddeqikrcvshsqricdmelkeqqcedkd 686
           ***99999999999999999999999999999999999999999999999999999999999999999999999999998888888888 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 687  knsllakkeaskcletgdacfdemnddelvaavlemskketslseshddedklssspdtgfggdddvqeiaenhepmeeervktsiltn 775
           88888888888888888888888888888888888887777777777777777777777777777777777777777666666666666 PP
   S: 268  .....................peekqke............................................................. 274
                                p     e                                                             
   Q: 776  lgvlqysdmakdfdenkenktP-----Easqndvdwlqydlerereeqelqqalaqslqeqearemkedddlkratelslqefnntlmd 859
           6666666666666666555550.....05555555555555555555566666666666666777777777777777777777778888 PP
   S: 275  ...................................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleet 326
                                              +++Y+Li+vv+H G s+ssGHY+++v++ +++ W++++D +V+ ++e++v++++
   Q: 860  gmvsdedsgneevldmeyseaeteelkknaetgdlPHSYRLISVVSHIGsSSSSGHYISDVYDVRKQaWFTYNDLEVSRTQETTVQSDR 948
           88888888888888888888888888999999999****************************88888********************* PP
   S: 327  gstaYvlfYkr 337
           ++++Y++fY++
   Q: 949  DRSGYIFFYMH 959
           *********98 PP
   

   UBD/Alpha-Helix/UIM
   S: 1    dEdeeLqlAlalSlqEee 18
           +Ed++L +A +lSlqE +
   Q: 837  KEDDDLKRATELSLQEFN 854
           69**************76 PP
   
Organism Xenopus tropicalis
Protein Sequence
(Fasta)
MALHSLHGPI RIHCLKVGTS KWKEGCCEVI EKDNKYCLVV NYNAGGMPTR FQLNQNIKTI 60
VVKPNGGTQS RFMLTLKDAS SLTIDKVPLK DAENLKHFLE SLDKATIVLL VKSNQGSGSF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132949|DUB,USP;UBD,UIM|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCAAATTGGT GCTTGCGTGA CAGTCGGCGC TCTGAGAGAA CTGGAAGGAG AGCAAGGAGA 60
ACCAGAGAAG GTGAGGGACG GGGGGCCGCC GGGAGAAGCA TACAATCACA GTGACAGGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132949|DUB,USP;UBD,UIM|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001400 Ailuropoda melanoleuca 65.33 0.00e+00 1139.00
IUUC-Apl-004033 Anas platyrhynchos 68.54 0.00e+00 1238.00
IUUC-Aca-005370 Anolis carolinensis 63.92 0.00e+00 1122.00
IUUC-Ame-011884 Astyanax mexicanus 57.06 0.00e+00 928.00
IUUC-Bta-012725 Bos taurus 64.34 0.00e+00 1113.00
IUUC-Cja-019939 Callithrix jacchus 64.88 0.00e+00 1106.00
IUUC-Cfa-020835 Canis familiaris 65.16 0.00e+00 1154.00
IUUC-Cpo-022067 Cavia porcellus 63.80 0.00e+00 1006.00
IUUC-Cre-022867 Chlamydomonas reinhardtii 28.80 5.00e-22 99.80
IUUC-Csa-023085 Chlorocebus sabaeus 65.15 0.00e+00 1133.00
IUUC-Cho-024390 Choloepus hoffmanni 49.04 2.00e-91 330.00
IUUC-Cin-025496 Ciona intestinalis 33.80 2.00e-45 176.00
IUUC-Csv-025812 Ciona savignyi 32.50 3.00e-39 156.00
IUUC-Dre-028255 Danio rerio 56.43 0.00e+00 883.00
IUUC-Dno-028986 Dasypus novemcinctus 64.50 0.00e+00 1114.00
IUUC-Dor-031062 Dipodomys ordii 55.31 3.00e-167 582.00
IUUC-Ete-032359 Echinops telfairi 56.83 2.00e-149 523.00
IUUC-Eca-033964 Equus caballus 65.10 0.00e+00 1136.00
IUUC-Eeu-034492 Erinaceus europaeus 63.57 1.00e-157 550.00
IUUC-Fca-036359 Felis catus 65.46 0.00e+00 1143.00
IUUC-Fal-037640 Ficedula albicollis 68.41 0.00e+00 1205.00
IUUC-Gmo-039600 Gadus morhua 54.84 0.00e+00 873.00
IUUC-Gga-040126 Gallus gallus 68.27 0.00e+00 1167.00
IUUC-Gac-041557 Gasterosteus aculeatus 54.46 0.00e+00 840.00
IUUC-Ggo-045571 Gorilla gorilla 62.79 0.00e+00 985.00
IUUC-Hsa-046043 Homo sapiens 65.12 0.00e+00 1119.00
IUUC-Itr-048207 Ictidomys tridecemlineatus 64.91 0.00e+00 1115.00
IUUC-Lch-050357 Latimeria chalumnae 61.82 0.00e+00 927.00
IUUC-Loc-052849 Lepisosteus oculatus 59.68 0.00e+00 954.00
IUUC-Laf-054570 Loxodonta africana 64.03 0.00e+00 1086.00
IUUC-Mcc-054989 Macaca mulatta 63.98 0.00e+00 1030.00
IUUC-Meu-056273 Macropus eugenii 47.89 7.00e-111 395.00
IUUC-Mga-059814 Meleagris gallopavo 66.67 0.00e+00 1153.00
IUUC-Mmr-061726 Microcebus murinus 65.35 0.00e+00 1132.00
IUUC-Mdo-062974 Monodelphis domestica 67.11 0.00e+00 1187.00
IUUC-Mmu-064069 Mus musculus 63.13 0.00e+00 1075.00
IUUC-Mpu-066008 Mustela putorius furo 65.26 0.00e+00 1123.00
IUUC-Mlu-068224 Myotis lucifugus 35.98 7.00e-120 424.00
IUUC-Nle-069259 Nomascus leucogenys 65.05 0.00e+00 1113.00
IUUC-Opr-070882 Ochotona princeps 63.36 1.00e-102 368.00
IUUC-Ont-072441 Oreochromis niloticus 55.05 0.00e+00 866.00
IUUC-Oan-073151 Ornithorhynchus anatinus 73.95 1.00e-102 365.00
IUUC-Ocu-074879 Oryctolagus cuniculus 64.75 0.00e+00 1110.00
IUUC-Ola-087007 Oryzias latipes 52.77 0.00e+00 820.00
IUUC-Oga-088385 Otolemur garnettii 64.69 0.00e+00 1126.00
IUUC-Oar-090305 Ovis aries 65.25 0.00e+00 1137.00
IUUC-Ptr-091299 Pan troglodytes 65.12 0.00e+00 1115.00
IUUC-Pan-091996 Papio anubis 65.80 0.00e+00 1111.00
IUUC-Psi-093176 Pelodiscus sinensis 67.90 0.00e+00 1225.00
IUUC-Pma-094331 Petromyzon marinus 45.72 0.00e+00 691.00
IUUC-Pfo-096503 Poecilia formosa 55.42 0.00e+00 848.00
IUUC-Pab-098543 Pongo abelii 68.68 0.00e+00 638.00
IUUC-Pca-101099 Procavia capensis 63.56 0.00e+00 880.00
IUUC-Pva-103163 Pteropus vampyrus 62.30 0.00e+00 752.00
IUUC-Rno-105766 Rattus norvegicus 63.40 0.00e+00 1073.00
IUUC-Sha-106610 Sarcophilus harrisii 63.88 0.00e+00 1089.00
IUUC-Sar-113624 Sorex araneus 39.71 1.00e-15 78.60
IUUC-Ssc-116353 Sus scrofa 64.31 0.00e+00 1100.00
IUUC-Tgu-116971 Taeniopygia guttata 68.07 0.00e+00 1180.00
IUUC-Tru-117932 Takifugu rubripes 44.41 4.00e-169 588.00
IUUC-Tsy-119185 Tarsius syrichta 61.61 0.00e+00 756.00
IUUC-Tni-119842 Tetraodon nigroviridis 61.28 4.00e-104 372.00
IUUC-Tbe-127281 Tupaia belangeri 50.82 4.00e-107 382.00
IUUC-Ttr-128177 Tursiops truncatus 70.79 0.00e+00 934.00
IUUC-Vpa-130031 Vicugna pacos 65.76 0.00e+00 1152.00
Created Date 25-Jun-2017

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