iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034122

UUCD1 version

UUC-EqC-01060

Ensembl Protein ID

ENSECAP00000007969.1

UniProt Accession

F7B7L7; F7B7L7_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000009628.1	ENSECAT00000010341.1	ENSECAP00000007969.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-68	231.9	198	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 198  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 277
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c+e d +s r+e+ +d++l+++g
   Q: 278  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKG 340
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ +lP+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 341  KK-----NIFESFVDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 423
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           ++ k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 424  TDPKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 504
           88777..*************************9834566************86666664446*******************87 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAGNHRLGPE AGDTDDPPRI TQNPVINGNV AMSDGHNTTE EDMEDDTSWR SEATFQFTVE 60
RFSRLSESVL SPPCFVRNLP WKIMVMPRFY PDRPHQKSVG FFLQCNAESD STSWSCHAQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAACCCCTC TCCAGCCCCA GCACATTCTG CCGCAGAGCC ATGCGGACAT GGCGGGGAAC 60
CACAGGCTGG GACCAGAAGG TGACTCAGGA CTTCAGATTG GGGTCCTTAA GGCTGATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0010216--P:maintenance of DNA methylation
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0050821--P:protein stabilization
GO:0006283--P:transcription-coupled nucleotide-excision repair
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ecb:100057484

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	33.30	3.00e-143	503.00
IUUC-Aml-002408	Ailuropoda melanoleuca	99.45	0.00e+00	2237.00
IUUC-Atr-003067	Amborella trichopoda	36.73	8.00e-123	434.00
IUUC-Apl-003558	Anas platyrhynchos	96.75	0.00e+00	2198.00
IUUC-Aca-004518	Anolis carolinensis	90.82	0.00e+00	2057.00
IUUC-Aly-006453	Arabidopsis lyrata	36.91	2.00e-160	560.00
IUUC-Ath-006591	Arabidopsis thaliana	36.33	3.00e-156	546.00
IUUC-Ago-007849	Ashbya gossypii	32.79	2.00e-139	490.00
IUUC-Acl-008327	Aspergillus clavatus	34.20	7.00e-171	594.00
IUUC-Afl-008491	Aspergillus flavus	34.85	3.00e-165	576.00
IUUC-Afu-008804	Aspergillus fumigatus	35.22	9.00e-163	567.00
IUUC-Ang-009776	Aspergillus niger	34.98	2.00e-162	566.00
IUUC-Aor-009998	Aspergillus oryzae	34.11	5.00e-157	548.00
IUUC-Ate-010428	Aspergillus terreus	34.79	6.00e-165	575.00
IUUC-Ame-010903	Astyanax mexicanus	93.36	0.00e+00	2129.00
IUUC-Bgr-012132	Blumeria graminis	32.10	7.00e-144	504.00
IUUC-Bta-013192	Bos taurus	98.89	0.00e+00	2206.00
IUUC-Bci-013924	Botrytis cinerea	34.04	5.00e-151	528.00
IUUC-Bdi-014920	Brachypodium distachyon	35.73	7.00e-157	548.00
IUUC-Bol-015224	Brassica oleracea	36.68	4.00e-157	549.00
IUUC-Bra-017448	Brassica rapa	36.46	1.00e-156	547.00
IUUC-Cel-018219	Caenorhabditis elegans	33.66	2.00e-155	543.00
IUUC-Cja-019006	Callithrix jacchus	98.16	0.00e+00	2203.00
IUUC-Cfa-020361	Canis familiaris	99.36	0.00e+00	2233.00
IUUC-Cpo-022320	Cavia porcellus	98.89	0.00e+00	2202.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	43.84	2.00e-91	329.00
IUUC-Csa-024050	Chlorocebus sabaeus	99.35	0.00e+00	2217.00
IUUC-Cho-024434	Choloepus hoffmanni	89.91	0.00e+00	1431.00
IUUC-Cin-025689	Ciona intestinalis	54.40	0.00e+00	1212.00
IUUC-Csv-025963	Ciona savignyi	52.32	0.00e+00	1162.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.42	1.00e-151	530.00
IUUC-Cne-026968	Cryptococcus neoformans	36.67	0.00e+00	628.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.69	6.00e-115	409.00
IUUC-Dre-028510	Danio rerio	93.54	0.00e+00	2130.00
IUUC-Dno-029696	Dasypus novemcinctus	98.99	0.00e+00	2222.00
IUUC-Dor-030611	Dipodomys ordii	83.75	0.00e+00	975.00
IUUC-Dse-031433	Dothistroma septosporum	34.83	5.00e-147	515.00
IUUC-Dme-031583	Drosophila melanogaster	48.86	0.00e+00	1039.00
IUUC-Ete-033191	Echinops telfairi	97.05	0.00e+00	2182.00
IUUC-Eeu-035292	Erinaceus europaeus	77.83	0.00e+00	681.00
IUUC-Fca-036377	Felis catus	99.26	0.00e+00	2229.00
IUUC-Fal-036964	Ficedula albicollis	96.87	0.00e+00	2159.00
IUUC-Fox-037695	Fusarium oxysporum	33.49	3.00e-159	556.00
IUUC-Fso-038084	Fusarium solani	33.54	4.00e-159	555.00
IUUC-Gmo-038644	Gadus morhua	93.04	0.00e+00	2123.00
IUUC-Ggr-040029	Gaeumannomyces graminis	33.67	1.00e-157	550.00
IUUC-Gga-040944	Gallus gallus	97.01	0.00e+00	2190.00
IUUC-Gac-041740	Gasterosteus aculeatus	93.50	0.00e+00	2128.00
IUUC-Gma-043300	Glycine max	36.54	5.00e-168	585.00
IUUC-Ggo-044947	Gorilla gorilla	99.17	0.00e+00	2229.00
IUUC-Hsa-046278	Homo sapiens	99.35	0.00e+00	2217.00
IUUC-Hvu-047749	Hordeum vulgare	37.12	3.00e-142	499.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	98.93	0.00e+00	1898.00
IUUC-Kpa-049121	Komagataella pastoris	31.12	4.00e-126	446.00
IUUC-Lch-049847	Latimeria chalumnae	96.19	0.00e+00	2176.00
IUUC-Lpe-051505	Leersia perrieri	35.40	7.00e-143	501.00
IUUC-Loc-052234	Lepisosteus oculatus	93.73	0.00e+00	1420.00
IUUC-Lma-053169	Leptosphaeria maculans	36.76	6.00e-168	585.00
IUUC-Laf-053566	Loxodonta africana	99.26	0.00e+00	2212.00
IUUC-Mcc-055549	Macaca mulatta	99.26	0.00e+00	2207.00
IUUC-Meu-056887	Macropus eugenii	87.97	0.00e+00	1280.00
IUUC-Mor-057149	Magnaporthe oryzae	34.78	2.00e-159	556.00
IUUC-Mpo-057536	Magnaporthe poae	33.61	3.00e-158	552.00
IUUC-Mtr-058583	Medicago truncatula	37.17	5.00e-164	572.00
IUUC-Mla-058899	Melampsora laricipopulina	36.89	2.00e-171	596.00
IUUC-Mga-060148	Meleagris gallopavo	96.41	0.00e+00	2204.00
IUUC-Mvi-060207	Microbotryum violaceum	37.82	0.00e+00	635.00
IUUC-Mmr-060946	Microcebus murinus	99.07	0.00e+00	2211.00
IUUC-Mdo-062079	Monodelphis domestica	90.47	0.00e+00	1973.00
IUUC-Mmu-063678	Mus musculus	98.42	0.00e+00	2196.00
IUUC-Mac-065416	Musa acuminata	36.98	5.00e-157	548.00
IUUC-Mpu-066744	Mustela putorius furo	99.24	0.00e+00	2166.00
IUUC-Mlu-067949	Myotis lucifugus	98.43	0.00e+00	2207.00
IUUC-Nfi-068342	Neosartorya fischeri	35.56	1.00e-162	567.00
IUUC-Ncr-068818	Neurospora crassa	33.80	4.00e-163	568.00
IUUC-Nle-070064	Nomascus leucogenys	99.26	0.00e+00	2215.00
IUUC-Opr-071001	Ochotona princeps	97.07	0.00e+00	1825.00
IUUC-Ont-072095	Oreochromis niloticus	93.17	0.00e+00	2126.00
IUUC-Oan-073483	Ornithorhynchus anatinus	97.82	0.00e+00	2143.00
IUUC-Ocu-073967	Oryctolagus cuniculus	98.10	0.00e+00	2133.00
IUUC-Oba-075811	Oryza barthii	33.70	8.00e-141	494.00
IUUC-Obr-076514	Oryza brachyantha	36.41	2.00e-155	543.00
IUUC-Ogl-077038	Oryza glaberrima	35.70	1.00e-150	527.00
IUUC-Ogu-078265	Oryza glumaepatula	34.10	2.00e-136	480.00
IUUC-Oin-079513	Oryza indica	34.77	7.00e-142	498.00
IUUC-Olo-081067	Oryza longistaminata	33.64	7.00e-139	488.00
IUUC-Ome-081879	Oryza meridionalis	36.19	5.00e-151	528.00
IUUC-Oni-082409	Oryza nivara	33.46	3.00e-140	493.00
IUUC-Opu-083199	Oryza punctata	35.17	4.00e-147	515.00
IUUC-Oru-085109	Oryza rufipogon	35.67	1.00e-146	514.00
IUUC-Osa-085418	Oryza sativa	37.24	4.00e-131	462.00
IUUC-Ola-086640	Oryzias latipes	93.50	0.00e+00	2123.00
IUUC-Olu-087874	Ostreococcus lucimarinus	33.67	2.00e-143	503.00
IUUC-Oga-089059	Otolemur garnettii	91.96	0.00e+00	2030.00
IUUC-Oar-089710	Ovis aries	98.71	0.00e+00	2220.00
IUUC-Ptr-091334	Pan troglodytes	99.17	0.00e+00	2229.00
IUUC-Pan-091717	Papio anubis	99.52	0.00e+00	2149.00
IUUC-Psi-093933	Pelodiscus sinensis	96.49	0.00e+00	2197.00
IUUC-Pma-094648	Petromyzon marinus	82.13	0.00e+00	1725.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.16	8.00e-150	524.00
IUUC-Ppa-096020	Physcomitrella patens	34.71	4.00e-162	565.00
IUUC-Pfo-096181	Poecilia formosa	93.08	0.00e+00	2123.00
IUUC-Pab-098231	Pongo abelii	96.59	0.00e+00	2159.00
IUUC-Pop-100083	Populus trichocarpa	36.52	1.00e-159	557.00
IUUC-Pca-100543	Procavia capensis	81.77	0.00e+00	1028.00
IUUC-Ppe-101523	Prunus persica	35.95	2.00e-154	540.00
IUUC-Pva-102472	Pteropus vampyrus	97.97	0.00e+00	2180.00
IUUC-Pgr-103463	Puccinia graminis	36.79	1.00e-170	593.00
IUUC-Ptt-103716	Puccinia triticina	37.85	1.00e-167	583.00
IUUC-Pte-104360	Pyrenophora teres	36.23	2.00e-151	530.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	35.85	1.00e-149	524.00
IUUC-Rno-105816	Rattus norvegicus	98.61	0.00e+00	2205.00
IUUC-Sce-106230	Saccharomyces cerevisiae	29.93	9.00e-123	435.00
IUUC-Sha-107439	Sarcophilus harrisii	97.95	0.00e+00	2185.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	33.27	5.00e-140	492.00
IUUC-Spo-108019	Schizosaccharomyces pombe	34.63	4.00e-145	509.00
IUUC-Smo-109308	Selaginella moellendorffii	35.95	4.00e-152	532.00
IUUC-Sit-110367	Setaria italica	36.25	1.00e-157	550.00
IUUC-Sly-111337	Solanum lycopersicum	37.97	4.00e-164	572.00
IUUC-Stu-112387	Solanum tuberosum	36.75	2.00e-165	576.00
IUUC-Sar-113685	Sorex araneus	97.97	0.00e+00	2199.00
IUUC-Sbi-114037	Sorghum bicolor	36.52	2.00e-158	553.00
IUUC-Sre-115156	Sporisorium reilianum	36.68	0.00e+00	629.00
IUUC-Ssc-116297	Sus scrofa	99.35	0.00e+00	2217.00
IUUC-Tgu-116767	Taeniopygia guttata	96.76	0.00e+00	2199.00
IUUC-Tru-118208	Takifugu rubripes	93.22	0.00e+00	2097.00
IUUC-Tsy-119277	Tarsius syrichta	89.93	0.00e+00	728.00
IUUC-Tni-119890	Tetraodon nigroviridis	93.22	0.00e+00	2098.00
IUUC-Tca-121696	Theobroma cacao	36.50	2.00e-156	546.00
IUUC-Tre-122169	Trichoderma reesei	32.61	2.00e-153	536.00
IUUC-Tvi-122600	Trichoderma virens	34.24	1.00e-160	560.00
IUUC-Tae-125264	Triticum aestivum	35.84	2.00e-155	543.00
IUUC-Tur-126287	Triticum urartu	35.22	1.00e-149	524.00
IUUC-Tme-127045	Tuber melanosporum	35.26	4.00e-166	578.00
IUUC-Tbe-127696	Tupaia belangeri	87.62	1.00e-159	556.00
IUUC-Ttr-129161	Tursiops truncatus	98.99	0.00e+00	2220.00
IUUC-Uma-129535	Ustilago maydis	37.28	0.00e+00	640.00
IUUC-Vda-129708	Verticillium dahliae	32.99	5.00e-159	555.00
IUUC-Vvi-131048	Vitis vinifera	35.70	2.00e-158	553.00
IUUC-Xtr-132073	Xenopus tropicalis	92.13	0.00e+00	2071.00
IUUC-Xma-133949	Xiphophorus maculatus	92.80	0.00e+00	2116.00
IUUC-Yli-134527	Yarrowia lipolytica	32.98	1.00e-139	491.00
IUUC-Zma-135550	Zea mays	35.25	3.00e-148	519.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence