iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aly-005581

UUCD1 version

UUC-ArL-01235

Ensembl Protein ID

fgenesh2_kg.2__801__AT1G65650.1

UniProt Accession

D7KSF3; D7KSF3_ARALL

Genbank Protein ID

EFH64696.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

GL348714

Gene Name

UCH2; ARALYDRAFT_475671

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.2__801__AT1G65650.1	fgenesh2_kg.2__801__AT1G65650.1	fgenesh2_kg.2__801__AT1G65650.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.30e-76	258.0	2	321

Active Site

Position(s)	Description	Evidence
82	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
157	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdedi 84
           +w+++esdPg+ft+l+++  vk++ qveelysLd ++l+ + +pv+gl++lFk++  ++  r          ++ +d 
   Q: 2    SWCTIESDPGVFTELIQQMQVKGV-QVEELYSLDLDSLNNL-RPVYGLIFLFKWQVGEKDDR---------PTI-QDQ 67
           7***********************.****************.*************9888888.........233.688 PP
   S: 85   iktiffakqvigNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrse 162
           ++++ffa+qvi+N+Cat+A+l  lln  ++  d+G++ls lke+tk + ++ k+la++n+++++++hns+ar+e++  
   Q: 68   VSNLFFANQVINNACATQAILAILLNSPEV--DIGPELSALKEFTKNFPSDLKGLAINNSEAIRAAHNSFARPEPFVP 143
           99*************************999..********************************************98 PP
   S: 163  perqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkkketeelkdklkvvr.aflerikllesdeirfnll 239
           +e+++++   ++++++hf+sy++++g lyeldglk+ P+ lg++  ++   + lk v+    eri+ +++ eirfnll
   Q: 144  EEQKAAT---KDDDVYHFISYIPVDGVLYELDGLKEGPISLGPCPGDQTGIEWLKMVQpVIQERIERYSQSEIRFNLL 218
           8877555...59********************************77765555555555445***************** PP
   S: 240  aivadrrviktlrlnvlkid.................keLlkLlkdieseeekieaqlddekekrkkfkiddirRten 300
           a+ ++r+ i+t+ l+ l+ +                 + + +L +++ s +e  + ++  e+ek  k+  ++irR++n
   Q: 219  AVIKNRKDIYTAELKELQRQreqllqqantcvdkseaEAVNALIEEVGSGIEAASDKIVMEEEKFMKWRTENIRRKHN 296
           *************998877789**************97788************************************* PP
   S: 301  ydeficifikdlaregilrklveet 325
           y  f++ f+k la++++l+ l e+ 
   Q: 297  YIPFLFNFLKLLAEKKQLKPLIEKA 321
           ********************99984 PP

Organism

Arabidopsis lyrata

Protein Sequence
(Fasta)

MSWCTIESDP GVFTELIQQM QVKGVQVEEL YSLDLDSLNN LRPVYGLIFL FKWQVGEKDD 60
RPTIQDQVSN LFFANQVINN ACATQAILAI LLNSPEVDIG PELSALKEFT KNFPSDLKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTGGCTAA GTTAAACCCT AATTCCCAAA TTGGAGTCAC GAAAGCAATC TCCAAATCTA 60
TCTCATTCGG TTCGAAGAAG CTTCAAAGGC GATTCCTTTA CTTTAGCTAA CTAGTAAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0010016--P:shoot system morphogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_475671

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	73.39	1.00e-135	475.00
IUUC-Aml-001866	Ailuropoda melanoleuca	47.22	9.00e-83	299.00
IUUC-Atr-002966	Amborella trichopoda	71.47	3.00e-128	451.00
IUUC-Apl-003306	Anas platyrhynchos	43.66	1.00e-75	276.00
IUUC-Aca-004763	Anolis carolinensis	47.04	6.00e-82	296.00
IUUC-Ath-007283	Arabidopsis thaliana	97.88	1.00e-176	610.00
IUUC-Ago-007999	Ashbya gossypii	42.19	8.00e-31	126.00
IUUC-Acl-008231	Aspergillus clavatus	51.90	1.00e-62	232.00
IUUC-Afl-008557	Aspergillus flavus	51.25	2.00e-60	224.00
IUUC-Afu-008988	Aspergillus fumigatus	51.67	2.00e-61	228.00
IUUC-Ani-009420	Aspergillus nidulans	42.77	1.00e-64	239.00
IUUC-Ang-009859	Aspergillus niger	48.98	4.00e-60	224.00
IUUC-Aor-010145	Aspergillus oryzae	51.25	2.00e-60	224.00
IUUC-Ate-010347	Aspergillus terreus	47.84	1.00e-60	226.00
IUUC-Ame-010791	Astyanax mexicanus	48.63	2.00e-85	308.00
IUUC-Bgr-012298	Blumeria graminis	42.28	1.00e-59	222.00
IUUC-Bta-013251	Bos taurus	48.15	2.00e-83	301.00
IUUC-Bci-013786	Botrytis cinerea	42.01	2.00e-62	232.00
IUUC-Bdi-014132	Brachypodium distachyon	74.55	9.00e-132	462.00
IUUC-Bol-015611	Brassica oleracea	89.70	4.00e-160	556.00
IUUC-Bra-017769	Brassica rapa	89.70	2.00e-160	556.00
IUUC-Cel-018604	Caenorhabditis elegans	39.70	7.00e-64	236.00
IUUC-Cja-019768	Callithrix jacchus	43.18	1.00e-77	282.00
IUUC-Cfa-020207	Canis familiaris	47.22	9.00e-83	299.00
IUUC-Cpo-021925	Cavia porcellus	44.75	7.00e-76	276.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	51.70	2.00e-84	304.00
IUUC-Csa-023958	Chlorocebus sabaeus	48.15	3.00e-83	301.00
IUUC-Cho-024928	Choloepus hoffmanni	55.41	8.00e-18	83.60
IUUC-Cin-025771	Ciona intestinalis	43.87	5.00e-71	260.00
IUUC-Csv-026149	Ciona savignyi	43.75	8.00e-75	273.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	35.42	6.00e-48	183.00
IUUC-Cne-026955	Cryptococcus neoformans	31.52	3.00e-45	174.00
IUUC-Cme-027104	Cyanidioschyzon merolae	30.53	1.00e-45	176.00
IUUC-Dre-027409	Danio rerio	46.50	9.00e-84	302.00
IUUC-Dno-028921	Dasypus novemcinctus	47.22	1.00e-82	299.00
IUUC-Dor-030891	Dipodomys ordii	38.93	1.00e-39	157.00
IUUC-Dse-031170	Dothistroma septosporum	41.34	3.00e-61	228.00
IUUC-Dme-031677	Drosophila melanogaster	46.36	2.00e-77	281.00
IUUC-Ete-032646	Echinops telfairi	46.15	5.00e-43	168.00
IUUC-Eca-033776	Equus caballus	46.05	4.00e-74	270.00
IUUC-Eeu-035305	Erinaceus europaeus	43.96	5.00e-38	150.00
IUUC-Fca-035846	Felis catus	43.59	3.00e-78	284.00
IUUC-Fal-037597	Ficedula albicollis	46.51	1.00e-73	268.00
IUUC-Fox-037670	Fusarium oxysporum	47.39	3.00e-51	194.00
IUUC-Fso-038243	Fusarium solani	48.26	1.00e-51	196.00
IUUC-Gmo-038499	Gadus morhua	44.44	1.00e-75	275.00
IUUC-Ggr-039975	Gaeumannomyces graminis	45.27	2.00e-53	201.00
IUUC-Gga-040904	Gallus gallus	47.89	1.00e-85	308.00
IUUC-Gac-042058	Gasterosteus aculeatus	47.84	3.00e-83	301.00
IUUC-Gma-043030	Glycine max	81.08	1.00e-146	511.00
IUUC-Ggo-044699	Gorilla gorilla	43.67	3.00e-71	261.00
IUUC-Hsa-046227	Homo sapiens	47.22	2.00e-83	301.00
IUUC-Hvu-047359	Hordeum vulgare	73.62	9.00e-135	472.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	43.66	1.00e-77	282.00
IUUC-Lch-049829	Latimeria chalumnae	48.60	8.00e-82	296.00
IUUC-Lpe-050899	Leersia perrieri	75.86	1.00e-130	458.00
IUUC-Loc-052264	Lepisosteus oculatus	47.08	2.00e-80	291.00
IUUC-Lma-053110	Leptosphaeria maculans	52.19	2.00e-56	211.00
IUUC-Laf-053639	Loxodonta africana	47.22	9.00e-83	299.00
IUUC-Mcc-055506	Macaca mulatta	48.15	4.00e-83	301.00
IUUC-Meu-056267	Macropus eugenii	43.15	6.00e-49	188.00
IUUC-Mor-057001	Magnaporthe oryzae	47.11	1.00e-57	216.00
IUUC-Mpo-057608	Magnaporthe poae	45.60	2.00e-37	147.00
IUUC-Mtr-057731	Medicago truncatula	79.64	2.00e-142	497.00
IUUC-Mla-059016	Melampsora laricipopulina	44.66	1.00e-43	168.00
IUUC-Mga-060178	Meleagris gallopavo	46.47	3.00e-76	277.00
IUUC-Mvi-060353	Microbotryum violaceum	37.92	2.00e-53	201.00
IUUC-Mmr-060738	Microcebus murinus	47.22	3.00e-83	300.00
IUUC-Mdo-062266	Monodelphis domestica	52.40	3.00e-61	227.00
IUUC-Mmu-063619	Mus musculus	48.15	3.00e-83	300.00
IUUC-Mac-065301	Musa acuminata	77.47	3.00e-146	510.00
IUUC-Mpu-066058	Mustela putorius furo	47.53	2.00e-82	298.00
IUUC-Mlu-067292	Myotis lucifugus	47.84	3.00e-83	300.00
IUUC-Nfi-068275	Neosartorya fischeri	51.48	1.00e-61	229.00
IUUC-Ncr-068713	Neurospora crassa	39.70	5.00e-59	220.00
IUUC-Nle-069013	Nomascus leucogenys	48.15	2.00e-83	302.00
IUUC-Opr-070628	Ochotona princeps	42.00	2.00e-71	262.00
IUUC-Ont-072688	Oreochromis niloticus	46.77	1.00e-81	295.00
IUUC-Oan-073004	Ornithorhynchus anatinus	52.38	1.00e-62	232.00
IUUC-Ocu-074303	Oryctolagus cuniculus	47.53	3.00e-82	298.00
IUUC-Oba-075002	Oryza barthii	74.85	5.00e-132	462.00
IUUC-Obr-076392	Oryza brachyantha	73.98	4.00e-129	453.00
IUUC-Ogl-077271	Oryza glaberrima	74.85	5.00e-132	462.00
IUUC-Ogu-078493	Oryza glumaepatula	75.15	4.00e-133	466.00
IUUC-Oin-080084	Oryza indica	75.15	4.00e-133	466.00
IUUC-Olo-080803	Oryza longistaminata	74.85	9.00e-133	465.00
IUUC-Ome-081146	Oryza meridionalis	73.94	7.00e-132	462.00
IUUC-Oni-082146	Oryza nivara	75.15	4.00e-133	466.00
IUUC-Opu-083633	Oryza punctata	75.86	2.00e-128	451.00
IUUC-Oru-084789	Oryza rufipogon	75.15	4.00e-133	466.00
IUUC-Osa-086196	Oryza sativa	75.15	4.00e-133	466.00
IUUC-Ola-087126	Oryzias latipes	47.22	2.00e-82	298.00
IUUC-Olu-087665	Ostreococcus lucimarinus	43.83	8.00e-70	256.00
IUUC-Oga-089140	Otolemur garnettii	43.59	2.00e-78	285.00
IUUC-Oar-090296	Ovis aries	47.68	1.00e-81	295.00
IUUC-Ptr-090566	Pan troglodytes	47.22	2.00e-83	301.00
IUUC-Pan-092052	Papio anubis	48.15	4.00e-83	301.00
IUUC-Psi-093723	Pelodiscus sinensis	47.18	1.00e-73	269.00
IUUC-Pma-094568	Petromyzon marinus	50.72	3.00e-60	224.00
IUUC-Pno-095120	Phaeosphaeria nodorum	50.00	1.00e-55	209.00
IUUC-Ppa-095761	Physcomitrella patens	70.26	1.00e-128	452.00
IUUC-Pfo-096210	Poecilia formosa	47.84	2.00e-83	301.00
IUUC-Pab-098463	Pongo abelii	47.22	3.00e-83	301.00
IUUC-Pop-099109	Populus trichocarpa	75.98	3.00e-140	490.00
IUUC-Pca-100108	Procavia capensis	52.38	5.00e-68	250.00
IUUC-Ppe-101176	Prunus persica	80.24	7.00e-142	495.00
IUUC-Pva-102629	Pteropus vampyrus	52.84	9.00e-70	256.00
IUUC-Pgr-103419	Puccinia graminis	45.83	4.00e-55	207.00
IUUC-Pte-104207	Pyrenophora teres	54.55	8.00e-40	155.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	52.84	1.00e-59	222.00
IUUC-Rno-105579	Rattus norvegicus	42.18	5.00e-71	260.00
IUUC-Sha-106894	Sarcophilus harrisii	46.53	1.00e-69	255.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	40.66	2.00e-65	241.00
IUUC-Spo-108371	Schizosaccharomyces pombe	44.59	3.00e-71	260.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	41.05	1.00e-50	192.00
IUUC-Smo-109396	Selaginella moellendorffii	73.09	9.00e-129	452.00
IUUC-Sit-110630	Setaria italica	73.33	2.00e-132	464.00
IUUC-Sly-110972	Solanum lycopersicum	80.45	2.00e-143	501.00
IUUC-Stu-112185	Solanum tuberosum	81.57	8.00e-156	541.00
IUUC-Sar-113294	Sorex araneus	41.43	3.00e-70	258.00
IUUC-Sbi-113951	Sorghum bicolor	72.73	1.00e-129	455.00
IUUC-Ssc-115501	Sus scrofa	46.03	1.00e-75	275.00
IUUC-Tgu-117152	Taeniopygia guttata	46.51	1.00e-73	268.00
IUUC-Tru-118388	Takifugu rubripes	46.91	1.00e-82	299.00
IUUC-Tsy-119109	Tarsius syrichta	47.22	3.00e-83	301.00
IUUC-Tni-120048	Tetraodon nigroviridis	47.22	4.00e-83	300.00
IUUC-Tca-121750	Theobroma cacao	80.00	3.00e-152	530.00
IUUC-Tre-122130	Trichoderma reesei	47.01	1.00e-56	212.00
IUUC-Tvi-122284	Trichoderma virens	47.41	3.00e-52	197.00
IUUC-Tae-124082	Triticum aestivum	73.93	4.00e-136	476.00
IUUC-Tme-127187	Tuber melanosporum	44.19	4.00e-70	257.00
IUUC-Tbe-127619	Tupaia belangeri	40.79	8.00e-56	209.00
IUUC-Ttr-128867	Tursiops truncatus	45.99	6.00e-57	213.00
IUUC-Vda-129912	Verticillium dahliae	38.28	1.00e-55	209.00
IUUC-Vpa-130552	Vicugna pacos	52.66	3.00e-61	228.00
IUUC-Vvi-130881	Vitis vinifera	79.34	8.00e-145	505.00
IUUC-Xtr-131934	Xenopus tropicalis	49.24	2.00e-87	314.00
IUUC-Xma-133312	Xiphophorus maculatus	47.52	1.00e-83	301.00
IUUC-Yli-134487	Yarrowia lipolytica	41.28	2.00e-51	195.00
IUUC-Zma-135639	Zea mays	63.49	7.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence