iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091256

UUCD1 version

UUC-PaT-01031

Ensembl Protein ID

ENSPTRP00000040235.3

UniProt Accession

H2R062; H2R062_PANTR

Genbank Protein ID

JAA08120.1; JAA13507.1; JAA34914.1

Protein Name

Ubiquitin-like modifier activating enzyme 5

Genbank Nucleotide ID

AACZ03026513; GABF01008638; GABE01009825

Gene Name

UBA5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000015404.5	ENSPTRT00000049800.3	ENSPTRP00000040235.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.00e-52	177.5	53	231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirl..wGeeaq.eklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnp 86
           Y+R+++l  +G++++ ek++++ v +vG+gg+G+ ++++L+ +G+g++ ++D+d+ve++n+nr F f+++++g sK+++a+++l+++np
   Q: 53   YSRLMALkrMGIVSDyEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSKVQAAEHTLRNINP 140
           9****************************************************************.*********************** PP
   S: 87   dvnveaheesiteleeeivFfkkf...........dvVvlaldnrearrkvnrlclnarvpliesgtlG..llGqvrviikgltecysc 162
           dv +e+h+++it+ e+ ++F++++           d+V++++dn+ear+++n++c ++    +esg+    + G+++ ii+g  +c  c
   Q: 141  DVLFEVHNYNITTVENFQHFMDRIsnggleegkpvDLVLSCVDNFEARMTINTACNELGQTWMESGVSEnaVSGHIQLIIPGESACFAC 229
           ******************************************************************9863367*************999 PP
   S: 163  sd 164
            +
   Q: 230  AP 231
           75 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAESVERLQQ RVQELERELA QERSLRVPRS GDGGGGRVRI EKMSSEVVDS NPYSRLMALK 60
RMGIVSDYEK IRTFAVAIVG VGGVGSVTAE MLTRCGIGKL LLFDYDKVEL ANMNRLFFQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTTTTTGC TGAGGGGGAG CGATGTCTGC GACGCACCGG AAGCGGCTCC GAGGAAGGCC 60
TGTGGGAGTC TCGGAGACGT GTCTGTCTGT GAGGCGCTGG GTGCACTTCC CCAGGGCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029752--D-isomer_DH_CS1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

PROSITE

PS00065--D_2_HYDROXYACID_DH_1

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0071566--F:UFM1 activating enzyme activity
GO:1990592--P:protein K69-linked ufmylation
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0034976--P:response to endoplasmic reticulum stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001324	Ailuropoda melanoleuca	96.12	0.00e+00	666.00
IUUC-Atr-002660	Amborella trichopoda	70.14	6.00e-112	397.00
IUUC-Apl-003722	Anas platyrhynchos	88.89	1.00e-160	558.00
IUUC-Aca-004584	Anolis carolinensis	88.60	8.00e-170	589.00
IUUC-Aly-005881	Arabidopsis lyrata	66.89	6.00e-110	390.00
IUUC-Ath-007286	Arabidopsis thaliana	71.02	1.00e-113	403.00
IUUC-Ame-011679	Astyanax mexicanus	83.33	3.00e-142	497.00
IUUC-Bta-012517	Bos taurus	96.16	0.00e+00	650.00
IUUC-Bdi-014894	Brachypodium distachyon	69.37	3.00e-111	394.00
IUUC-Bol-016054	Brassica oleracea	71.28	5.00e-114	404.00
IUUC-Bra-016708	Brassica rapa	61.90	3.00e-115	408.00
IUUC-Cel-018424	Caenorhabditis elegans	62.60	1.00e-118	419.00
IUUC-Cja-019825	Callithrix jacchus	97.05	5.00e-149	520.00
IUUC-Cfa-021160	Canis familiaris	96.53	0.00e+00	698.00
IUUC-Cpo-022255	Cavia porcellus	90.70	0.00e+00	644.00
IUUC-Csa-023827	Chlorocebus sabaeus	98.02	0.00e+00	712.00
IUUC-Cho-025078	Choloepus hoffmanni	90.76	0.00e+00	640.00
IUUC-Cin-025217	Ciona intestinalis	71.04	8.00e-153	533.00
IUUC-Dre-027578	Danio rerio	82.09	2.00e-165	575.00
IUUC-Dno-029330	Dasypus novemcinctus	91.21	0.00e+00	650.00
IUUC-Dor-030425	Dipodomys ordii	59.71	2.00e-106	378.00
IUUC-Dme-031645	Drosophila melanogaster	61.84	9.00e-130	456.00
IUUC-Ete-032912	Echinops telfairi	94.74	6.00e-55	207.00
IUUC-Eca-033247	Equus caballus	97.81	0.00e+00	658.00
IUUC-Eeu-034472	Erinaceus europaeus	96.29	4.00e-179	620.00
IUUC-Fca-035684	Felis catus	97.55	0.00e+00	669.00
IUUC-Fal-037654	Ficedula albicollis	86.41	4.00e-163	567.00
IUUC-Gmo-039449	Gadus morhua	68.03	9.00e-128	449.00
IUUC-Gga-041051	Gallus gallus	87.95	2.00e-169	588.00
IUUC-Gac-042325	Gasterosteus aculeatus	76.43	5.00e-166	577.00
IUUC-Gma-043136	Glycine max	67.52	1.00e-119	422.00
IUUC-Ggo-044414	Gorilla gorilla	99.50	0.00e+00	745.00
IUUC-Hsa-046777	Homo sapiens	99.50	0.00e+00	751.00
IUUC-Hvu-047549	Hordeum vulgare	67.97	1.00e-94	339.00
IUUC-Itr-048175	Ictidomys tridecemlineatus	95.99	0.00e+00	672.00
IUUC-Lch-050142	Latimeria chalumnae	81.73	1.00e-175	608.00
IUUC-Lpe-050769	Leersia perrieri	66.31	1.00e-101	363.00
IUUC-Loc-052405	Lepisosteus oculatus	83.75	1.00e-159	555.00
IUUC-Laf-054152	Loxodonta africana	95.54	0.00e+00	693.00
IUUC-Mcc-055618	Macaca mulatta	99.43	0.00e+00	642.00
IUUC-Meu-056486	Macropus eugenii	91.45	6.00e-167	580.00
IUUC-Mtr-057871	Medicago truncatula	71.99	4.00e-116	411.00
IUUC-Mga-059284	Meleagris gallopavo	87.95	8.00e-170	589.00
IUUC-Mmr-061242	Microcebus murinus	96.03	0.00e+00	674.00
IUUC-Mdo-063034	Monodelphis domestica	90.76	1.00e-179	622.00
IUUC-Mmu-064322	Mus musculus	88.80	0.00e+00	627.00
IUUC-Mac-065128	Musa acuminata	60.85	6.00e-69	258.00
IUUC-Mpu-066438	Mustela putorius furo	97.26	0.00e+00	664.00
IUUC-Mlu-067578	Myotis lucifugus	96.99	0.00e+00	661.00
IUUC-Nle-069542	Nomascus leucogenys	98.76	0.00e+00	705.00
IUUC-Opr-070710	Ochotona princeps	88.37	0.00e+00	632.00
IUUC-Ont-072067	Oreochromis niloticus	87.46	3.00e-162	564.00
IUUC-Oan-073593	Ornithorhynchus anatinus	88.92	1.00e-168	585.00
IUUC-Ocu-073964	Oryctolagus cuniculus	92.57	0.00e+00	678.00
IUUC-Oba-075476	Oryza barthii	64.76	3.00e-113	401.00
IUUC-Obr-076517	Oryza brachyantha	70.57	7.00e-112	397.00
IUUC-Ogu-078664	Oryza glumaepatula	65.08	1.00e-113	403.00
IUUC-Olo-081012	Oryza longistaminata	64.76	3.00e-113	401.00
IUUC-Ome-081129	Oryza meridionalis	69.58	3.00e-113	401.00
IUUC-Oni-082265	Oryza nivara	64.33	7.00e-112	397.00
IUUC-Opu-084121	Oryza punctata	70.57	2.00e-112	399.00
IUUC-Oru-084451	Oryza rufipogon	70.00	3.00e-97	348.00
IUUC-Osa-086132	Oryza sativa	64.76	3.00e-113	401.00
IUUC-Ola-086842	Oryzias latipes	81.84	3.00e-159	554.00
IUUC-Oga-088160	Otolemur garnettii	95.05	0.00e+00	656.00
IUUC-Oar-089362	Ovis aries	96.71	0.00e+00	660.00
IUUC-Pan-092913	Papio anubis	98.46	0.00e+00	685.00
IUUC-Psi-093740	Pelodiscus sinensis	89.74	2.00e-160	558.00
IUUC-Pma-094485	Petromyzon marinus	84.30	2.00e-107	380.00
IUUC-Ppa-095673	Physcomitrella patens	69.46	1.00e-113	403.00
IUUC-Pfo-096196	Poecilia formosa	82.45	2.00e-164	571.00
IUUC-Pab-098449	Pongo abelii	98.76	0.00e+00	743.00
IUUC-Pop-099049	Populus trichocarpa	66.35	6.00e-112	397.00
IUUC-Pca-100917	Procavia capensis	96.23	3.00e-120	424.00
IUUC-Ppe-101797	Prunus persica	69.46	2.00e-116	412.00
IUUC-Pva-102852	Pteropus vampyrus	97.28	0.00e+00	659.00
IUUC-Rno-105213	Rattus norvegicus	88.30	0.00e+00	630.00
IUUC-Sha-107569	Sarcophilus harrisii	85.33	0.00e+00	628.00
IUUC-Smo-109146	Selaginella moellendorffii	67.19	3.00e-114	405.00
IUUC-Sit-109794	Setaria italica	67.45	1.00e-114	406.00
IUUC-Sly-111622	Solanum lycopersicum	71.28	2.00e-114	405.00
IUUC-Stu-112522	Solanum tuberosum	70.63	6.00e-115	407.00
IUUC-Sar-113045	Sorex araneus	82.72	2.00e-166	577.00
IUUC-Sbi-113861	Sorghum bicolor	64.87	8.00e-114	403.00
IUUC-Ssc-115290	Sus scrofa	97.05	1.00e-163	568.00
IUUC-Tgu-117125	Taeniopygia guttata	86.34	9.00e-165	572.00
IUUC-Tru-118041	Takifugu rubripes	84.24	2.00e-167	582.00
IUUC-Tsy-119300	Tarsius syrichta	86.00	5.00e-153	533.00
IUUC-Tni-120310	Tetraodon nigroviridis	83.70	3.00e-161	560.00
IUUC-Tca-121405	Theobroma cacao	66.35	2.00e-115	408.00
IUUC-Tae-123656	Triticum aestivum	64.76	9.00e-113	400.00
IUUC-Tur-125985	Triticum urartu	68.86	2.00e-112	399.00
IUUC-Tbe-127478	Tupaia belangeri	75.25	1.00e-156	545.00
IUUC-Ttr-128169	Tursiops truncatus	75.50	2.00e-145	508.00
IUUC-Vpa-130508	Vicugna pacos	90.00	7.00e-162	562.00
IUUC-Vvi-131252	Vitis vinifera	66.67	1.00e-115	409.00
IUUC-Xtr-132776	Xenopus tropicalis	83.83	1.00e-164	572.00
IUUC-Xma-133110	Xiphophorus maculatus	81.38	3.00e-165	574.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence