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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064210
UUCD1 version UUC-MuM-00620
Ensembl Protein ID ENSMUSP00000022225.5
UniProt Accession Q8BGX0; Q8C2B6; Q8CDA4; Q8CDA7; TRI23_MOUSE
Genbank Protein ID BAC27156.1; BAC27160.1; BAC30304.1; BAC31152.1; BAC40654.1; AAH56390.1; AAH59017.1
Protein Name E3 ubiquitin-protein ligase TRIM23; ADP-ribosylation factor domain-containing protein 1; GTP-binding protein ARD-1; RING-type E3 ubiquitin transferase TRIM23; Tripartite motif-containing protein 23
Genbank Nucleotide ID AK030843; AK030862; AK039280; AK042070; AK088922; BC056390; BC059017
Gene Name Trim23; Arfd1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000021712.14 ENSMUST00000022225.11 ENSMUSP00000022225.5
ENSMUSG00000021712.14 ENSMUST00000069187.11 ENSMUSP00000070767.5
ENSMUSG00000021712.14 ENSMUST00000160230.1 ENSMUSP00000124425.1
ENSMUSG00000021712.14 ENSMUST00000069174.5 ENSMUSP00000069371.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 97.74 0.00e+00 1156.00 IUUC-Hsa-045801
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Acts as an E3 ubiquitin-protein ligase. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
 Acts as an E3 ubiquitin-protein ligase. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.
Protein Sequence
(Fasta)
MAALAVNKPG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 60
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGHIGQY GAAEEAIGTS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064210|E3,RING|Mus musculus
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Nucleotide Sequence
(Fasta)
ATGCGCCGAG GCTTCTGGGT AGGACGCTCA ACCCCTCCTC TCAGTAAAAG GCTCTCCTGC 60
AGCTGTGGCG CGGCTCCATC CAGGATGGCT GCCCTCGCTG TAAACAAGCC CGGAGCCGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064210|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0333--Golgi apparatus
KW-0342--GTP-binding
KW-0458--Lysosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003649--Bbox_C
IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR024156--Small_GTPase_ARF
IPR006689--Small_GTPase_ARF/SAR
IPR000315--Znf_B-box
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS51417--ARF
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00025--Arf
PF00643--zf-B_box
PF14634--zf-RING_5
PRINTS

PR00328--SAR1GTPBP
SMART

SM00502--BBC
SM00336--BBOX
SM00184--RING
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0000139--C:Golgi membrane
GO:0005765--C:lysosomal membrane
GO:0005634--C:nucleus
GO:0019003--F:GDP binding
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0042802--F:identical protein binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
GO:0007264--P:small GTPase mediated signal transduction
KEGG mmu:81003
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001685 Ailuropoda melanoleuca 98.44 0.00e+00 1132.00
IUUC-Apl-003280 Anas platyrhynchos 95.49 0.00e+00 1094.00
IUUC-Aca-004587 Anolis carolinensis 92.21 0.00e+00 1007.00
IUUC-Ame-010760 Astyanax mexicanus 88.72 0.00e+00 1054.00
IUUC-Bta-013139 Bos taurus 96.03 0.00e+00 1107.00
IUUC-Cel-018197 Caenorhabditis elegans 36.53 2.00e-95 343.00
IUUC-Cja-019407 Callithrix jacchus 97.56 0.00e+00 1123.00
IUUC-Cfa-020758 Canis familiaris 97.89 0.00e+00 1116.00
IUUC-Cpo-022050 Cavia porcellus 97.74 0.00e+00 1157.00
IUUC-Csa-023938 Chlorocebus sabaeus 97.74 0.00e+00 1125.00
IUUC-Cho-024793 Choloepus hoffmanni 69.86 0.00e+00 766.00
IUUC-Cin-025424 Ciona intestinalis 57.14 0.00e+00 638.00
IUUC-Csv-025949 Ciona savignyi 56.66 7.00e-180 623.00
IUUC-Dre-028835 Danio rerio 88.52 0.00e+00 1051.00
IUUC-Dno-029080 Dasypus novemcinctus 89.18 0.00e+00 1027.00
IUUC-Dor-031092 Dipodomys ordii 90.94 0.00e+00 1061.00
IUUC-Ete-033169 Echinops telfairi 84.15 0.00e+00 945.00
IUUC-Eca-033509 Equus caballus 98.78 0.00e+00 1137.00
IUUC-Eeu-034669 Erinaceus europaeus 99.12 5.00e-132 464.00
IUUC-Fca-035813 Felis catus 98.61 0.00e+00 1138.00
IUUC-Fal-037222 Ficedula albicollis 93.30 0.00e+00 1103.00
IUUC-Gmo-038996 Gadus morhua 87.91 0.00e+00 1046.00
IUUC-Gga-040181 Gallus gallus 94.29 0.00e+00 1114.00
IUUC-Gac-041763 Gasterosteus aculeatus 87.05 0.00e+00 1036.00
IUUC-Ggo-044808 Gorilla gorilla 91.84 0.00e+00 1058.00
IUUC-Hsa-045801 Homo sapiens 97.74 0.00e+00 1125.00
IUUC-Itr-048568 Ictidomys tridecemlineatus 98.43 0.00e+00 1133.00
IUUC-Lch-049531 Latimeria chalumnae 92.22 0.00e+00 1063.00
IUUC-Loc-052929 Lepisosteus oculatus 89.29 0.00e+00 1063.00
IUUC-Laf-053593 Loxodonta africana 98.43 0.00e+00 1134.00
IUUC-Mcc-055065 Macaca mulatta 97.74 0.00e+00 1125.00
IUUC-Meu-056372 Macropus eugenii 98.67 7.00e-131 461.00
IUUC-Mga-059665 Meleagris gallopavo 95.56 0.00e+00 961.00
IUUC-Mmr-061643 Microcebus murinus 98.43 0.00e+00 1132.00
IUUC-Mdo-062624 Monodelphis domestica 93.67 0.00e+00 1107.00
IUUC-Mpu-066292 Mustela putorius furo 98.03 0.00e+00 1095.00
IUUC-Mlu-066952 Myotis lucifugus 98.26 0.00e+00 1131.00
IUUC-Nle-069002 Nomascus leucogenys 97.74 0.00e+00 1125.00
IUUC-Opr-070405 Ochotona princeps 88.50 0.00e+00 1030.00
IUUC-Ont-071487 Oreochromis niloticus 88.37 0.00e+00 1046.00
IUUC-Oan-073274 Ornithorhynchus anatinus 96.36 0.00e+00 984.00
IUUC-Ocu-074788 Oryctolagus cuniculus 98.26 0.00e+00 1130.00
IUUC-Ola-086339 Oryzias latipes 86.96 0.00e+00 1038.00
IUUC-Oga-089037 Otolemur garnettii 98.26 0.00e+00 1132.00
IUUC-Oar-089458 Ovis aries 98.21 0.00e+00 1107.00
IUUC-Pan-092120 Papio anubis 97.06 0.00e+00 1112.00
IUUC-Psi-093157 Pelodiscus sinensis 92.92 0.00e+00 1107.00
IUUC-Pfo-096904 Poecilia formosa 87.61 0.00e+00 1037.00
IUUC-Pab-098358 Pongo abelii 97.74 0.00e+00 1125.00
IUUC-Pva-102674 Pteropus vampyrus 96.69 0.00e+00 1111.00
IUUC-Rno-105352 Rattus norvegicus 99.30 0.00e+00 1174.00
IUUC-Sha-106532 Sarcophilus harrisii 86.89 2.00e-61 226.00
IUUC-Sar-113483 Sorex araneus 95.65 5.00e-151 528.00
IUUC-Ssc-116170 Sus scrofa 98.61 0.00e+00 1139.00
IUUC-Tgu-116968 Taeniopygia guttata 93.74 0.00e+00 1097.00
IUUC-Tru-118246 Takifugu rubripes 87.76 0.00e+00 1034.00
IUUC-Tni-120692 Tetraodon nigroviridis 89.62 0.00e+00 1029.00
IUUC-Ttr-128956 Tursiops truncatus 98.43 0.00e+00 1134.00
IUUC-Vpa-130291 Vicugna pacos 91.64 0.00e+00 1070.00
IUUC-Xtr-132331 Xenopus tropicalis 91.89 0.00e+00 921.00
Created Date 25-Jun-2017

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