iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088799

Ensembl Protein ID

ENSOGAP00000000921.2

UniProt Accession

H0WHQ6; H0WHQ6_OTOGA

Genbank Protein ID

ENSOGAP00000000921

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03103654

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000001030.2	ENSOGAT00000001031.2	ENSOGAP00000000921.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-29	101.3	1190	1224
UBD/Beta-Prp	1.30e-43	149.3	1294	1507

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v cl+ +d+ll +Gs D t+kvW+l tg  
   Q: 1190 GHTKAVLCLDSTDDLLFTGSKDRTCKVWNLVTGQE 1224
           89999***98666*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e++++++ ++p+g +++ +++ ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g       
   Q: 1294 SGENQINQIALNPTG-TFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQisNGqDLIITGSKDHYIKMFDVTEGALGTVsp 1379
           56789*********9.99**************************************9888*****************9998765466 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++++  + l+sGs D+ ++ Wdl++++ll++   +h+d v  l   +  + l+sg + g +klw++ t   v
   Q: 1380 thnFEPPHYDGIEALTIQG--DTLFSGSRDNGIKKWDLAQKDLLQQVPNAHKDWVCALGAVPGHPVLLSGCRGGILKLWNMDTFVPV 1464
           6878999999999999999..99************************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW...dlrsgdll 257
            +++gh+++++ + +   ++++ ++++D+++riW   +l+ g++ 
   Q: 1465 GEMKGHDSPINAICVN--STHIFTAADDRTVRIWkarNLQDGQIS 1507
           ***********99888..****************99999988876 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

LYNEEVLDLF DTTRDIDAKN KKSNIRIHED STGGIYTVGV TTRTVNTESE MMQCLKLGAL 60
SRTTASTQMN VQSSRSHAIF TIHVCQTRVC PQIDTENGTD NKIISESSQM NEFETLTAKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTCTTAGA GCTCTTTGCA CAGATTCTAC CCGCAGTAGC TTATTTATTT TTAATGATGT 60
AGAAACCTCT TTCAAGGCTC CTCAGTTGCT TGGCCTCTTG GCACTGTTTA TATACTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	95.21	0.00e+00	2719.00
IUUC-Apl-003353	Anas platyrhynchos	83.09	0.00e+00	2327.00
IUUC-Aca-004467	Anolis carolinensis	83.54	0.00e+00	2416.00
IUUC-Ame-011430	Astyanax mexicanus	65.64	0.00e+00	1302.00
IUUC-Bta-013485	Bos taurus	93.57	0.00e+00	2625.00
IUUC-Cel-018402	Caenorhabditis elegans	52.14	2.00e-98	354.00
IUUC-Cja-019385	Callithrix jacchus	92.34	0.00e+00	2637.00
IUUC-Cfa-020986	Canis familiaris	94.76	0.00e+00	2682.00
IUUC-Cpo-022297	Cavia porcellus	90.75	0.00e+00	2563.00
IUUC-Csa-023685	Chlorocebus sabaeus	93.64	0.00e+00	2673.00
IUUC-Cho-024531	Choloepus hoffmanni	91.01	0.00e+00	1073.00
IUUC-Cin-025160	Ciona intestinalis	47.98	6.00e-88	318.00
IUUC-Dre-028532	Danio rerio	65.54	0.00e+00	1311.00
IUUC-Dno-029972	Dasypus novemcinctus	89.92	0.00e+00	2488.00
IUUC-Ete-032872	Echinops telfairi	79.19	0.00e+00	1028.00
IUUC-Eca-033518	Equus caballus	94.49	0.00e+00	2682.00
IUUC-Fca-036197	Felis catus	95.28	0.00e+00	2682.00
IUUC-Fal-037534	Ficedula albicollis	82.79	0.00e+00	2344.00
IUUC-Gmo-039407	Gadus morhua	65.03	0.00e+00	1269.00
IUUC-Gga-040687	Gallus gallus	84.62	0.00e+00	1628.00
IUUC-Gac-041626	Gasterosteus aculeatus	66.38	0.00e+00	1964.00
IUUC-Ggo-044457	Gorilla gorilla	95.02	0.00e+00	2699.00
IUUC-Hsa-046372	Homo sapiens	95.02	0.00e+00	2696.00
IUUC-Lch-049786	Latimeria chalumnae	57.72	0.00e+00	1619.00
IUUC-Loc-052689	Lepisosteus oculatus	74.45	0.00e+00	2122.00
IUUC-Laf-054018	Loxodonta africana	88.50	0.00e+00	2455.00
IUUC-Mcc-055558	Macaca mulatta	94.82	0.00e+00	2689.00
IUUC-Meu-056080	Macropus eugenii	83.25	0.00e+00	1625.00
IUUC-Mga-059283	Meleagris gallopavo	84.99	0.00e+00	2366.00
IUUC-Mmr-060773	Microcebus murinus	95.26	0.00e+00	2645.00
IUUC-Mdo-062688	Monodelphis domestica	89.44	0.00e+00	2602.00
IUUC-Mmu-063997	Mus musculus	91.16	0.00e+00	2534.00
IUUC-Mpu-066354	Mustela putorius furo	92.79	0.00e+00	2662.00
IUUC-Mlu-067599	Myotis lucifugus	93.53	0.00e+00	2615.00
IUUC-Nle-069477	Nomascus leucogenys	95.15	0.00e+00	2700.00
IUUC-Opr-070188	Ochotona princeps	80.20	0.00e+00	1765.00
IUUC-Ont-071938	Oreochromis niloticus	66.99	0.00e+00	1344.00
IUUC-Oan-073055	Ornithorhynchus anatinus	87.66	0.00e+00	2332.00
IUUC-Ocu-074302	Oryctolagus cuniculus	91.76	0.00e+00	2603.00
IUUC-Ola-087491	Oryzias latipes	62.87	0.00e+00	1639.00
IUUC-Oar-089629	Ovis aries	92.00	0.00e+00	2617.00
IUUC-Pan-092214	Papio anubis	92.98	0.00e+00	2664.00
IUUC-Psi-093757	Pelodiscus sinensis	80.96	0.00e+00	2239.00
IUUC-Pfo-096978	Poecilia formosa	64.40	0.00e+00	1301.00
IUUC-Pab-097984	Pongo abelii	95.08	0.00e+00	2660.00
IUUC-Pca-101061	Procavia capensis	79.62	0.00e+00	1444.00
IUUC-Pva-102306	Pteropus vampyrus	92.66	0.00e+00	2588.00
IUUC-Rno-105354	Rattus norvegicus	89.91	0.00e+00	2501.00
IUUC-Sha-106938	Sarcophilus harrisii	88.50	0.00e+00	1792.00
IUUC-Ssc-115810	Sus scrofa	93.98	0.00e+00	2627.00
IUUC-Tgu-117076	Taeniopygia guttata	80.56	0.00e+00	2212.00
IUUC-Tru-117904	Takifugu rubripes	58.93	0.00e+00	1108.00
IUUC-Tsy-119020	Tarsius syrichta	93.18	0.00e+00	2685.00
IUUC-Tni-120813	Tetraodon nigroviridis	63.59	0.00e+00	1245.00
IUUC-Tbe-127494	Tupaia belangeri	79.74	0.00e+00	998.00
IUUC-Ttr-128393	Tursiops truncatus	86.75	0.00e+00	2419.00
IUUC-Vpa-130675	Vicugna pacos	81.71	0.00e+00	765.00
IUUC-Xtr-132829	Xenopus tropicalis	77.21	0.00e+00	2222.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence