iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000010902.1	ENSONIT00000013728.1	ENSONIP00000013718.1
ENSONIG00000010902.1	ENSONIT00000013729.1	ENSONIP00000013719.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.40e-10	39.0	13	87
E3 activity/RING/RING	9.60e-11	42.5	17	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqpl.teedlvPnltlrrliqawceen 72
           ++f C+I le+++ Pv++p+G+++ +++I  + + +++     +cP++++++ +  +l  nltl+++ +++ +  
   Q: 13   DQFTCSICLEVFNKPVTTPCGHSFCQTCISSYWDGSKRsaktyQCPLCKESFlKRPELHINLTLKEITEQFKQMA 87
           68*******************************8888889999********8688899***********998765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle f + p+++pCgH f+++C+   w + ++ s k+ +CPlC+
   Q: 17   CSICLEVFNK-PVTTPCGHSFCQTCIsSYW-DGSKRSAKTYQCPLCK 61
           ********99.***************5555.888889*********7 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAMSLPAAFL SEDQFTCSIC LEVFNKPVTT PCGHSFCQTC ISSYWDGSKR SAKTYQCPLC 60
KESFLKRPEL HINLTLKEIT EQFKQMASSP VAERLGGMEP SRSPSHHNQP LSPGFQRQRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAATCCA GACTGACAGG AGCAAGAGAA GGAGAGCAAC GAGCCACAGG GAACATCTCG 60
TACAAACACT CAAATATAAC CTCTCTCCTG AAACTGCAGG TAAGACATGT TAACTAACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0001666--P:response to hypoxia

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011213	Astyanax mexicanus	52.21	2.00e-167	582.00
IUUC-Dre-027365	Danio rerio	52.59	7.00e-177	613.00
IUUC-Gac-042042	Gasterosteus aculeatus	61.41	0.00e+00	700.00
IUUC-Pfo-097223	Poecilia formosa	64.62	0.00e+00	737.00
IUUC-Tru-118751	Takifugu rubripes	65.05	2.00e-150	526.00
IUUC-Tni-119658	Tetraodon nigroviridis	71.18	2.00e-175	608.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence