iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055453

UUCD1 version

UUC-MaM-01019

Ensembl Protein ID

ENSMMUP00000018144.3

UniProt Accession

H9EWW6; F6TDF9; H9EWW6_MACMU

Genbank Protein ID

AFE66875.1; AFH32088.1

Protein Name

Ubiquitin-conjugating enzyme E2 T

Genbank Nucleotide ID

JSUE03003024; JU475284

Gene Name

UBE2T

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000013795.3	ENSMMUT00000019373.3	ENSMMUP00000018144.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.10e-45	155.0	6	145

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rlk+el+ l+++pp+gi++ ++++ ++++++++ilG ++tpYe+gvFkle+ +pe+YPf+PP+++flt+i+hPn++++G++Cl++lk  
   Q: 6    RLKRELHMLATEPPPGITCWQDKD-QMDDLRAQILGGANTPYEKGVFKLEVIIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKlp 93
           99**********************.7************************************************************998 PP
   S: 88   eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++ +W+p l++++vl+siq l++epnp++pl +++++++k n+  + k++r+
   Q: 94   PKGAWRPSLNIATVLTSIQLLMSEPNPDDPLMADISSEFKYNKPVFLKNARQ 145
           99******************************************99999875 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLRAQILG GANTPYEKGV FKLEVIIPER 60
YPFEPPQIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNIATVLTS IQLLMSEPNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCACAATC TTCTCCAGAC AGGGGGCGGA GCTACGCCAA CCGTCCGAGG TCGCGCAGGC 60
GCTGGTACCA AGTTGGTCCG CCGGTTGCCG CGTTGTGAGG GGTGTCCGCG CAGGTAAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005730--C:nucleolus
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006281--P:DNA repair
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination

KEGG

mcc:705911

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	56.29	1.00e-47	184.00
IUUC-Aml-001392	Ailuropoda melanoleuca	87.24	6.00e-102	362.00
IUUC-Atr-003069	Amborella trichopoda	47.45	3.00e-52	198.00
IUUC-Apl-003914	Anas platyrhynchos	80.77	2.00e-77	280.00
IUUC-Aca-004381	Anolis carolinensis	72.22	8.00e-83	299.00
IUUC-Aly-006059	Arabidopsis lyrata	53.16	3.00e-46	179.00
IUUC-Ath-007669	Arabidopsis thaliana	55.33	1.00e-43	171.00
IUUC-Ame-011372	Astyanax mexicanus	66.12	2.00e-70	258.00
IUUC-Bta-012479	Bos taurus	81.22	1.00e-92	331.00
IUUC-Bdi-014043	Brachypodium distachyon	49.50	1.00e-54	207.00
IUUC-Bol-016011	Brassica oleracea	51.61	1.00e-43	171.00
IUUC-Bra-017419	Brassica rapa	51.61	3.00e-43	169.00
IUUC-Cja-019773	Callithrix jacchus	91.92	3.00e-107	380.00
IUUC-Cfa-020043	Canis familiaris	89.29	2.00e-102	364.00
IUUC-Cpo-021481	Cavia porcellus	88.83	2.00e-103	367.00
IUUC-Csa-024083	Chlorocebus sabaeus	99.49	1.00e-115	408.00
IUUC-Cho-024386	Choloepus hoffmanni	89.07	3.00e-97	347.00
IUUC-Cin-025419	Ciona intestinalis	66.23	2.00e-63	233.00
IUUC-Csv-026224	Ciona savignyi	67.53	4.00e-64	237.00
IUUC-Cme-027179	Cyanidioschyzon merolae	49.68	2.00e-41	161.00
IUUC-Dre-028800	Danio rerio	76.92	4.00e-74	270.00
IUUC-Dno-029833	Dasypus novemcinctus	90.36	2.00e-105	374.00
IUUC-Ete-032625	Echinops telfairi	88.46	5.00e-76	275.00
IUUC-Eca-033821	Equus caballus	95.54	4.00e-88	316.00
IUUC-Eeu-034578	Erinaceus europaeus	86.13	3.00e-67	246.00
IUUC-Fca-036398	Felis catus	89.80	3.00e-103	367.00
IUUC-Fal-037564	Ficedula albicollis	71.72	3.00e-79	287.00
IUUC-Gmo-039142	Gadus morhua	80.89	1.00e-75	274.00
IUUC-Gga-041054	Gallus gallus	69.90	5.00e-77	280.00
IUUC-Gac-041370	Gasterosteus aculeatus	77.71	1.00e-74	271.00
IUUC-Ggo-045370	Gorilla gorilla	95.94	3.00e-113	400.00
IUUC-Hsa-046513	Homo sapiens	96.45	8.00e-114	402.00
IUUC-Hvu-047694	Hordeum vulgare	55.63	3.00e-49	189.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	87.82	1.00e-103	368.00
IUUC-Lch-050484	Latimeria chalumnae	72.67	4.00e-71	260.00
IUUC-Loc-051967	Lepisosteus oculatus	77.07	5.00e-74	270.00
IUUC-Laf-053377	Loxodonta africana	89.34	8.00e-106	375.00
IUUC-Meu-056745	Macropus eugenii	80.10	6.00e-92	329.00
IUUC-Mga-059729	Meleagris gallopavo	69.90	5.00e-77	280.00
IUUC-Mmr-060581	Microcebus murinus	91.88	4.00e-109	386.00
IUUC-Mdo-062434	Monodelphis domestica	81.63	4.00e-89	322.00
IUUC-Mmu-064379	Mus musculus	83.76	5.00e-96	343.00
IUUC-Mac-064647	Musa acuminata	56.94	2.00e-46	178.00
IUUC-Mpu-066713	Mustela putorius furo	87.82	6.00e-102	362.00
IUUC-Mlu-067525	Myotis lucifugus	90.91	3.00e-83	300.00
IUUC-Nle-069757	Nomascus leucogenys	95.94	2.00e-113	400.00
IUUC-Opr-070756	Ochotona princeps	84.26	9.00e-100	355.00
IUUC-Ont-071956	Oreochromis niloticus	72.58	1.00e-76	278.00
IUUC-Oan-072745	Ornithorhynchus anatinus	85.28	3.00e-83	300.00
IUUC-Ocu-074423	Oryctolagus cuniculus	88.32	2.00e-103	367.00
IUUC-Oba-075569	Oryza barthii	58.28	8.00e-50	191.00
IUUC-Obr-076131	Oryza brachyantha	58.28	8.00e-50	191.00
IUUC-Ogl-077132	Oryza glaberrima	58.28	8.00e-50	191.00
IUUC-Ogu-078880	Oryza glumaepatula	58.94	3.00e-50	192.00
IUUC-Oin-079748	Oryza indica	58.94	3.00e-50	192.00
IUUC-Olo-080501	Oryza longistaminata	58.94	1.00e-50	194.00
IUUC-Ome-081248	Oryza meridionalis	58.28	8.00e-50	191.00
IUUC-Oni-083033	Oryza nivara	58.94	3.00e-50	192.00
IUUC-Opu-083664	Oryza punctata	58.94	2.00e-50	193.00
IUUC-Oru-084580	Oryza rufipogon	58.94	3.00e-50	192.00
IUUC-Osa-085721	Oryza sativa	58.94	3.00e-50	192.00
IUUC-Ola-087559	Oryzias latipes	75.76	9.00e-74	269.00
IUUC-Oga-088420	Otolemur garnettii	91.41	4.00e-106	376.00
IUUC-Oar-090082	Ovis aries	78.39	3.00e-89	320.00
IUUC-Ptr-091134	Pan troglodytes	95.94	2.00e-113	400.00
IUUC-Pan-091735	Papio anubis	99.49	1.00e-115	408.00
IUUC-Psi-094064	Pelodiscus sinensis	74.33	2.00e-81	294.00
IUUC-Pma-094609	Petromyzon marinus	72.19	2.00e-67	247.00
IUUC-Ppa-095553	Physcomitrella patens	58.94	4.00e-50	192.00
IUUC-Pfo-096710	Poecilia formosa	68.59	9.00e-74	269.00
IUUC-Pab-098126	Pongo abelii	96.45	8.00e-114	402.00
IUUC-Pop-099108	Populus trichocarpa	54.61	1.00e-47	184.00
IUUC-Pca-100338	Procavia capensis	87.31	2.00e-101	360.00
IUUC-Ppe-101239	Prunus persica	57.97	2.00e-44	173.00
IUUC-Pva-102756	Pteropus vampyrus	79.45	4.00e-67	246.00
IUUC-Rno-105211	Rattus norvegicus	79.19	2.00e-89	321.00
IUUC-Sha-106969	Sarcophilus harrisii	74.63	7.00e-82	296.00
IUUC-Smo-109052	Selaginella moellendorffii	55.48	2.00e-45	174.00
IUUC-Sit-110464	Setaria italica	58.50	3.00e-48	186.00
IUUC-Sly-110971	Solanum lycopersicum	59.46	8.00e-48	185.00
IUUC-Stu-112126	Solanum tuberosum	60.14	4.00e-48	186.00
IUUC-Sar-113633	Sorex araneus	80.90	1.00e-91	328.00
IUUC-Sbi-114875	Sorghum bicolor	58.28	1.00e-49	191.00
IUUC-Ssc-116375	Sus scrofa	82.74	2.00e-90	324.00
IUUC-Tgu-117292	Taeniopygia guttata	81.70	7.00e-75	272.00
IUUC-Tru-118157	Takifugu rubripes	67.31	1.00e-59	221.00
IUUC-Tsy-119260	Tarsius syrichta	89.85	6.00e-104	369.00
IUUC-Tni-120162	Tetraodon nigroviridis	72.02	1.00e-73	268.00
IUUC-Tca-121255	Theobroma cacao	55.28	5.00e-37	149.00
IUUC-Tae-123184	Triticum aestivum	56.29	1.00e-47	184.00
IUUC-Tbe-127296	Tupaia belangeri	90.36	2.00e-106	377.00
IUUC-Ttr-128443	Tursiops truncatus	83.92	4.00e-95	340.00
IUUC-Vpa-130689	Vicugna pacos	80.20	6.00e-92	329.00
IUUC-Vvi-130925	Vitis vinifera	56.49	5.00e-47	180.00
IUUC-Xma-133779	Xiphophorus maculatus	71.58	3.00e-74	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence