iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052586

Ensembl Protein ID

ENSLOCP00000017996.1

UniProt Accession

W5NBI7; W5NBI7_LEPOC

Genbank Protein ID

ENSLOCP00000017996

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01004949

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000014621.1	ENSLOCT00000018028.1	ENSLOCP00000017996.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-10	41.3	13	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            +++ y+++++++ +L + kGdv+++i   ++d +W k+ k+  g++G +P+n+v+k
   Q: 13   ECIAKYNFQGTTEQDLPFSKGDVLTII-GVTKDPNWYKA-KNNMGREGTIPANYVQK 67
           68999**********************.***********.69*************87 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSGIQTVWPS GTECIAKYNF QGTTEQDLPF SKGDVLTIIG VTKDPNWYKA KNNMGREGTI 60
PANYVQKREG VKSGGKLSLM PWFHGKITRE QAERLLYPPE TGLFLVREST NYPGDYTLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACGGGCAG TGGTGTGGCT GGCGAGGTGC GCACGCGCAG ACGAGCCGTC TGAATGAGGG 60
ACCATTTCCT CTTGGAGGCC TGTGTGTTTT GCAGCGACTG AAGGCCAGTT CCTCGGCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0060027--P:convergent extension involved in gastrulation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004391	Anolis carolinensis	88.00	0.00e+00	842.00
IUUC-Cin-025513	Ciona intestinalis	54.65	2.00e-145	508.00
IUUC-Csv-025899	Ciona savignyi	50.94	9.00e-135	473.00
IUUC-Fal-037215	Ficedula albicollis	89.56	0.00e+00	849.00
IUUC-Gmo-039103	Gadus morhua	91.20	0.00e+00	856.00
IUUC-Gga-040506	Gallus gallus	88.89	0.00e+00	845.00
IUUC-Meu-056387	Macropus eugenii	88.44	0.00e+00	843.00
IUUC-Mga-060040	Meleagris gallopavo	87.67	0.00e+00	822.00
IUUC-Mdo-061871	Monodelphis domestica	88.22	0.00e+00	842.00
IUUC-Ont-072457	Oreochromis niloticus	88.71	0.00e+00	831.00
IUUC-Ola-087366	Oryzias latipes	93.38	0.00e+00	837.00
IUUC-Oga-087928	Otolemur garnettii	87.78	0.00e+00	842.00
IUUC-Pfo-096126	Poecilia formosa	87.47	0.00e+00	825.00
IUUC-Sha-106987	Sarcophilus harrisii	88.44	0.00e+00	845.00
IUUC-Tru-118712	Takifugu rubripes	86.24	0.00e+00	801.00
IUUC-Tni-119856	Tetraodon nigroviridis	85.78	0.00e+00	808.00
IUUC-Xtr-132763	Xenopus tropicalis	82.71	0.00e+00	795.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence