iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006105.4	ENSCAFT00000015651.4	ENSCAFP00000014485.3
ENSCAFG00000006105.4	ENSCAFT00000009886.3	ENSCAFP00000009177.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-55	182.0	143	178
UBD/Beta-Prp	4.50e-81	272.6	59	312

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht +v+c +f +d +l+vs+s D+tik+WD++   +
   Q: 143  HTHWVRCAKFsPDgRLIVSCSEDKTIKIWDTTNKQC 178
           9**********999****************987665 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           hk+v+t+v+fsp ++lla++srd+t+++w  ++  + ++++ h+a+v++v+fs dg++l+t+seD+ ikvw++     +++l +h++ v
   Q: 59   HKDVVTSVQFSPLGNLLASASRDRTVRLWIPDKRGKSSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWNMYRQRFLYSLYRHTHWV 147
           89*************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
           ++ +fsp+g  +vs s+d+ti++wd+ ++qc++  +s   g+ n v ++p+g +++s++ D tv++Wd++ +kll++ +  h + v+++
   Q: 148  RCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVN-NFSDSVGFANFVDFNPNGTCIASAGSDHTVKIWDIRVNKLLQHYQV-HSGGVNCV 234
           *********************************.*********************************************8.******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlql 262
           sf+++g++++++s dgt+k+ dl +g+ ++tl+ght +v  v fs+ +e++ sg++D ++ +W  + +  ++  ++++
   Q: 235  SFHPSGNYIITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFSSGGADTQVLLWrtNFDYLNCKDMIKR 312
           ***************************************************************997777777777665 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

PLPFQEDPVL ERYFKGHKAA ITSVDFSPSG KQLATASWDT FLMLWNCKPQ ARAFRYVGHK 60
DVVTSVQFSP LGNLLASASR DRTVRLWIPD KRGKSSEFKA HTAPVRSVDF SADGQFLATA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCTCCCCT TCCAGGAGGA CCCGGTCCTG GAGCGGTATT TTAAGGGCCA CAAAGCTGCG 60
ATCACCTCCG TGGACTTCAG TCCCAGCGGC AAACAGCTTG GTGAGTTCTG CTCTGGGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0008283--P:cell proliferation
GO:0060271--P:cilium assembly
GO:0001895--P:retina homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002219	Ailuropoda melanoleuca	94.18	0.00e+00	862.00
IUUC-Apl-004219	Anas platyrhynchos	62.56	4.00e-161	560.00
IUUC-Aca-005197	Anolis carolinensis	59.00	7.00e-168	583.00
IUUC-Ame-011000	Astyanax mexicanus	56.09	1.00e-155	543.00
IUUC-Bta-012706	Bos taurus	92.37	0.00e+00	891.00
IUUC-Cja-019185	Callithrix jacchus	85.41	0.00e+00	816.00
IUUC-Cpo-022351	Cavia porcellus	84.52	0.00e+00	837.00
IUUC-Csa-023032	Chlorocebus sabaeus	85.41	0.00e+00	809.00
IUUC-Cho-024508	Choloepus hoffmanni	82.93	0.00e+00	690.00
IUUC-Dre-028703	Danio rerio	55.77	7.00e-155	540.00
IUUC-Dno-028915	Dasypus novemcinctus	91.22	0.00e+00	843.00
IUUC-Dor-030306	Dipodomys ordii	76.36	0.00e+00	657.00
IUUC-Ete-032353	Echinops telfairi	75.33	0.00e+00	687.00
IUUC-Eca-034136	Equus caballus	92.58	0.00e+00	836.00
IUUC-Eeu-034611	Erinaceus europaeus	81.40	0.00e+00	639.00
IUUC-Fca-036205	Felis catus	94.04	0.00e+00	817.00
IUUC-Fal-036947	Ficedula albicollis	52.22	5.00e-135	474.00
IUUC-Gga-040847	Gallus gallus	60.94	6.00e-161	560.00
IUUC-Ggo-045194	Gorilla gorilla	90.27	0.00e+00	882.00
IUUC-Hsa-047026	Homo sapiens	90.27	0.00e+00	882.00
IUUC-Itr-048943	Ictidomys tridecemlineatus	87.22	0.00e+00	810.00
IUUC-Lch-050067	Latimeria chalumnae	59.79	6.00e-171	593.00
IUUC-Loc-052409	Lepisosteus oculatus	59.06	4.00e-164	571.00
IUUC-Laf-053428	Loxodonta africana	91.54	0.00e+00	865.00
IUUC-Mcc-054772	Macaca mulatta	90.91	0.00e+00	881.00
IUUC-Meu-056496	Macropus eugenii	75.27	1.00e-166	579.00
IUUC-Mga-059276	Meleagris gallopavo	59.06	1.00e-161	562.00
IUUC-Mmr-061525	Microcebus murinus	90.27	0.00e+00	878.00
IUUC-Mdo-062351	Monodelphis domestica	71.51	0.00e+00	725.00
IUUC-Mmu-063834	Mus musculus	82.24	0.00e+00	813.00
IUUC-Mpu-066453	Mustela putorius furo	92.60	0.00e+00	884.00
IUUC-Mlu-067909	Myotis lucifugus	90.34	0.00e+00	817.00
IUUC-Nle-069206	Nomascus leucogenys	89.85	0.00e+00	881.00
IUUC-Opr-070566	Ochotona princeps	76.74	0.00e+00	731.00
IUUC-Oan-073726	Ornithorhynchus anatinus	68.14	1.00e-174	605.00
IUUC-Ocu-074639	Oryctolagus cuniculus	90.91	0.00e+00	884.00
IUUC-Ola-086913	Oryzias latipes	52.13	9.00e-142	496.00
IUUC-Oga-088061	Otolemur garnettii	91.20	0.00e+00	662.00
IUUC-Oar-090228	Ovis aries	86.80	0.00e+00	874.00
IUUC-Ptr-091420	Pan troglodytes	90.49	0.00e+00	884.00
IUUC-Pan-092228	Papio anubis	90.70	0.00e+00	880.00
IUUC-Psi-093309	Pelodiscus sinensis	63.91	3.00e-172	597.00
IUUC-Pab-098109	Pongo abelii	90.70	0.00e+00	886.00
IUUC-Pca-101012	Procavia capensis	69.13	0.00e+00	631.00
IUUC-Pva-102712	Pteropus vampyrus	92.18	0.00e+00	889.00
IUUC-Rno-105260	Rattus norvegicus	82.45	0.00e+00	814.00
IUUC-Sar-113446	Sorex araneus	78.44	0.00e+00	761.00
IUUC-Ssc-115794	Sus scrofa	95.05	0.00e+00	729.00
IUUC-Tgu-116770	Taeniopygia guttata	54.07	1.00e-140	492.00
IUUC-Tru-117968	Takifugu rubripes	54.33	3.00e-144	504.00
IUUC-Tsy-119316	Tarsius syrichta	75.00	0.00e+00	667.00
IUUC-Tni-119953	Tetraodon nigroviridis	48.31	9.00e-125	440.00
IUUC-Tbe-128071	Tupaia belangeri	86.41	0.00e+00	762.00
IUUC-Ttr-129267	Tursiops truncatus	92.18	0.00e+00	891.00
IUUC-Vpa-130823	Vicugna pacos	83.79	3.00e-178	617.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence